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1. 发明申请

US20070031043A1 System for and method of intelligently directed segmentation analysis for automated microscope systems 审中-公开
标题翻译：用于自动显微镜系统的智能定向分割分析系统和方法
公开(公告)号：US20070031043A1
公开(公告)日：2007-02-08
申请号：US11343544
申请日：2006-01-30
申请人： Cynthia Perz , Robert Ellis , Jose De La Torre-Bueno
发明人： Cynthia Perz , Robert Ellis , Jose De La Torre-Bueno
IPC分类号： G06K9/62 , G06K9/00
CPC分类号： G06K9/0014 , G06T7/11 , G06T2207/10056 , G06T2207/20016 , G06T2207/20021 , G06T2207/20076 , G06T2207/20132 , G06T2207/30024
摘要： The present disclosure includes systems and techniques relating to intelligently directed segmentation analysis for automated microscope systems. In general, in one implementation, the technique includes obtaining an image of at least a portion of a scan region including a biological specimen, partitioning the obtained image into zelles, determining one or more parameters of the zelles, performing a cluster analysis on the one or more parameters of the zelles, differentiating tissue of greater interest from tissue of lesser interest in the obtained image based on the cluster analysis and based on a test being performed for the biological specimen, and storing more information for the tissue of greater interest than information for the tissue of lesser interest. The cluster analysis can be a multivariate statistical cluster analysis, and the zelles can be test-dependent zelles (e.g., having dimensions defined according to the test being performed for the biological specimen).
摘要翻译：本公开包括与用于自动显微镜系统的智能定向分割分析有关的系统和技术。通常，在一个实施方式中，该技术包括获得包括生物样本的扫描区域的至少一部分的图像，将获得的图像划分为zelles，确定zell的一个或多个参数，对该图像执行聚类分析或更多参数，基于聚类分析，并且基于对生物样本进行的测试，并且比信息存储更多的感兴趣的组织的信息，将获得的图像中较不感兴趣的组织感兴趣的组织区分为更多的组织对于较不感兴趣的组织。聚类分析可以是多变量统计聚类分析，并且zelles可以是测试依赖性zelles（例如，具有根据为生物样本进行的测试而定义的维度）。

2. 发明申请

US20070280517A1 Serial section analysis for computer-controlled microscopic imaging 有权
标题翻译：计算机显微镜成像的序列分析
公开(公告)号：US20070280517A1
公开(公告)日：2007-12-06
申请号：US11472820
申请日：2006-06-21
申请人： Jose De La Torre-Bueno , Cynthia Perz , Robert Ellis
发明人： Jose De La Torre-Bueno , Cynthia Perz , Robert Ellis
IPC分类号： G06K9/00 , G06K9/32
CPC分类号： G06T7/33 , G06T2207/10056 , G06T2207/30024
摘要： Automated projection of serial section images in microscopic imaging systems. A computer-controlled microscope that is connected electrically to a controller that has a display device. A batch of serial section slides includes a series of serial section slides, each of which has a microscope slide, a sample, and an interesting area. If one of the images is misregistered, then the images may be transformed.
摘要翻译：在显微镜成像系统中自动投影串联图像。一种与具有显示装置的控制器电连接的计算机控制的显微镜。一批连续片幻灯片包括一系列连续片段幻灯片，每个幻灯片都有一个显微镜幻灯片，一个样本和一个有趣的区域。如果其中一个图像被错误注册，则可能会转换图像。

3. 发明申请

US20070029462A1 Repositioning inaccuracies in an automated imaging system 有权
标题翻译：在自动化成像系统中重新定位不准确
公开(公告)号：US20070029462A1
公开(公告)日：2007-02-08
申请号：US11198018
申请日：2005-08-04
申请人： Cynthia Perz , Robert Ellis
发明人： Cynthia Perz , Robert Ellis
IPC分类号： H01L27/00
CPC分类号： G03B5/00
摘要： Systems and techniques for reducing repositioning inaccuracies in imaging systems. Initial image data and positional information is received and cross-correlated with additional image data and positional information. An offset may be determined based on the cross-correlation.
摘要翻译：用于减少成像系统中重新定位不准确度的系统和技术。初始图像数据和位置信息被接收并与附加图像数据和位置信息相互关联。可以基于互相关来确定偏移。

4. 发明授权

US08888713B2 Safety blood collection assembly with indicator 有权
标题翻译：带指示器的安全采血组件
公开(公告)号：US08888713B2
公开(公告)日：2014-11-18
申请号：US12206299
申请日：2008-09-08
申请人： Jamieson Crawford , Robert Ellis , Bradley M. Wilkinson , Benjamin Bartfeld , C. Mark Newby , Chee Leong Alvin Tan , Jon Moh , Stanley Sim , Neville Yu Leng Chia
发明人： Jamieson Crawford , Robert Ellis , Bradley M. Wilkinson , Benjamin Bartfeld , C. Mark Newby , Chee Leong Alvin Tan , Jon Moh , Stanley Sim , Neville Yu Leng Chia
IPC分类号： A61B5/00 , B65D81/00 , A61B5/15 , A61M5/32 , A61M5/50
CPC分类号： A61B5/1535 , A61B5/1422 , A61B5/1444 , A61B5/15003 , A61B5/150213 , A61B5/150259 , A61B5/150389 , A61B5/150496 , A61B5/150572 , A61B5/150587 , A61B5/150603 , A61B5/150641 , A61B5/150656 , A61B5/150671 , A61B5/150717 , A61B5/150732 , A61B5/1545 , A61M5/3202 , A61M5/3216 , A61M5/5086 , A61M2005/3217
摘要： A blood collection assembly includes a housing and a cannula extending distally from the housing including a patient end, and a cannula shield removably engaged with a portion of the housing. The cannula shield is capable of shielding at least the patient end of the cannula, and includes a safety shield engagement. The assembly includes a pivoting safety shield engaged with a portion of the housing, which is transitionable from a retracted position in which the patient end of the cannula is exposed, to an extended position in which the patient end of the cannula is shielded by at least a portion of the safety shield. The safety shield includes at least one locking tab releasably engageable with the safety shield engagement, wherein the locking tab is fixedly engageable with a portion of the housing in the extended position.
摘要翻译：采血组件包括壳体和从壳体向远侧延伸的套管，包括患者端，以及可拆卸地与壳体的一部分接合的套管屏蔽。插管屏蔽能够至少屏蔽插管的患者端，并且包括安全屏蔽接合。该组件包括与壳体的一部分接合的枢转安全护罩，其可从套管的患者端露出的缩回位置转换到其中插管的患者端至少被屏蔽的延伸位置安全护罩的一部分。安全护罩包括可释放地与安全屏蔽接合部接合的至少一个锁定突舌，其中锁定突出部可在伸出位置与壳体的一部分牢固地接合。

5. 发明授权

US08548633B2 Battery pack control circuit for handheld battery operated device 有权
标题翻译：手持电池供电装置的电池组控制电路
公开(公告)号：US08548633B2
公开(公告)日：2013-10-01
申请号：US12956990
申请日：2010-11-30
申请人： Paul Adams , Robert Ellis , James Newton
发明人： Paul Adams , Robert Ellis , James Newton
IPC分类号： G05D3/12
CPC分类号： F21V29/70 , F21L4/005 , H01M10/052 , H01M10/345 , H01M10/425 , H01M10/48
摘要： A heat sink for a handheld device is formed as a one piece chassis for supporting heat-producing circuits inside the device while having heat radiating surfaces outside the device. In another embodiment a battery pack control circuit under microprocessor control allows battery packs having different battery chemistries and characteristics to be interchanged in the same device without switches or adapters. Control of operating modes of the device despite changes in the battery pack including battery chemistry, state of charge, available voltage, or desired operating mode are automatic. The microprocessor measures the battery pack characteristics, using look up tables in a suitable program to adjust the circuit operating modes. The microprocessor also responds to sequential switch contact closures in setting operating modes.
摘要翻译：用于手持设备的散热器形成为一体式底架，用于在设备内部具有热辐射表面的同时支撑设备内部的发热电路。在另一个实施例中，微处理器控制下的电池组控制电路允许具有不同电池化学性质和特性的电池组在没有开关或适配器的同一装置中互换。尽管包括电池化学，充电状态，可用电压或所需的操作模式在内的电池组发生变化，但是控制器件的工作模式是自动的。微处理器测量电池组特性，使用适当程序中的查找表来调整电路工作模式。在设置工作模式时，微处理器还会响应顺序开关触点闭合。

6. 发明申请

US20100211402A1 Clinical Guidelines Engine 有权
标题翻译：临床指南引擎
公开(公告)号：US20100211402A1
公开(公告)日：2010-08-19
申请号：US12377301
申请日：2008-01-03
申请人： Timothy Eggena , Bryan Rosenberger , Robert Hale , Robert Nary , Robert Ellis , Patrick Cline
发明人： Timothy Eggena , Bryan Rosenberger , Robert Hale , Robert Nary , Robert Ellis , Patrick Cline
IPC分类号： G06Q10/00 , G06Q50/00 , G06F3/048
CPC分类号： G06F19/327 , G06F19/00 , G06Q10/10 , G06Q50/22 , G16H40/20
摘要： A medical guideline integration engine is presented. The engine imports medical guideline information from disparate sources based on various guideline standards into a knowledge base. The knowledge base houses the information in a database. Upon request, the engine retrieves the information from the knowledge base and converts the information into a desired guideline format.
摘要翻译：介绍了医疗指南整合引擎。引擎根据各种指导标准将不同来源的医疗指南信息输入知识库。知识库将信息存储在数据库中。根据请求，引擎从知识库中检索信息，并将信息转换成所需的准则格式。

7. 发明授权

US07682565B2 Assay apparatus and method using microfluidic arrays 有权
标题翻译：使用微流控阵列的测定装置和方法
公开(公告)号：US07682565B2
公开(公告)日：2010-03-23
申请号：US10744580
申请日：2003-12-22
申请人： John Linton , Karl Yoder , Robert Hess , Leila Hasan , Robert Ellis , Tanya S. Kanigan , Kristine Friesen , Arrin Katz , Colin Brenan , Tom Morrison , Javier Garcia
发明人： John Linton , Karl Yoder , Robert Hess , Leila Hasan , Robert Ellis , Tanya S. Kanigan , Kristine Friesen , Arrin Katz , Colin Brenan , Tom Morrison , Javier Garcia
IPC分类号： G01N31/22 , G01N21/01 , G01N21/77
CPC分类号： C12Q1/6858 , B01L3/5025 , B01L3/5027 , B01L3/508 , B01L3/50853 , B01L3/50857 , B01L7/52 , B01L2200/16 , B01L2300/021 , B01L2300/0609 , B01L2300/0636 , B01L2300/0819 , B01L2300/0829 , B01L2300/16 , B01L2300/1822 , B01L2300/1838 , G01N21/03 , G01N21/15 , G01N21/253 , G01N2021/0346 , G01N2021/056 , G01N2021/158 , Y10T436/11 , Y10T436/25 , Y10T436/2575
摘要： A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.
摘要翻译：用于容纳至少一个样品和试剂用于分析的系统。该系统包括一对平行的盖，其至少一个是透光的，其中一对透光盖形成顶部，并且其中一对形成底部。框架设置在盖之间，以相对于盖限定内部空间。框架和盖子彼此相关联以形成壳体，该壳体基本上与液体紧密。微流体阵列设置在内部体积中。阵列包括具有一对相对表面的厚度的材料片，以及穿过表面之间的厚度的多个通孔，通孔包含至少一个样品和试剂。

8. 外观设计

USD611139S1 Safety blood collection needle device 有权
标题翻译：安全采血针装置
公开(公告)号：USD611139S1
公开(公告)日：2010-03-02
申请号：US29323445
申请日：2008-08-26
申请人： Jamieson Crawford , Robert Ellis , Benjamin Bartfeld , Bradley M. Wilkinson , Neville Yu Leng Chia
设计人： Jamieson Crawford , Robert Ellis , Benjamin Bartfeld , Bradley M. Wilkinson , Neville Yu Leng Chia

9. 发明申请

US20070159008A1 Circuit for illuminating multiple light emitting devices 有权
标题翻译：用于照亮多个发光器件的电路
公开(公告)号：US20070159008A1
公开(公告)日：2007-07-12
申请号：US11329338
申请日：2006-01-10
申请人： Bijan Bayat , James Newton , Robert Ellis
发明人： Bijan Bayat , James Newton , Robert Ellis
IPC分类号： B23K11/24
CPC分类号： F21L4/02 , F21V29/75 , F21V29/76 , F21Y2115/10 , H05B33/0803 , H05B33/0815 , Y10T307/74
摘要： A single drive circuit is configured to drive disparate current loads of first and second combinations of compact light emitting devices with respective regulated constant currents. Standard push ON, push OFF latching switches provide independent control of the two lighting loads wherein each switch operates in three states including momentary ON, continuous ON, and OFF. The circuit is readily adapted to providing continuous or pulsed drive to the lighting arrays. Circuits for dimming control, strobe control, and a low battery indicator are also described.
摘要翻译：单个驱动电路被配置为驱动具有相应调节恒定电流的小型发光器件的第一和第二组合的不同电流负载。标准按钮ON，推OFF闭锁开关提供对两个照明负载的独立控制，其中每个开关以三个状态操作，包括瞬时ON，连续ON和OFF。该电路容易适用于向照明阵列提供连续或脉冲驱动。还描述了用于调光控制，频闪控制和低电量指示器的电路。

10. 发明申请

US20070140540A1 Automated Detection of Objects in a Biological Sample 失效
标题翻译：生物样品中物体的自动检测
公开(公告)号：US20070140540A1
公开(公告)日：2007-06-21
申请号：US11674652
申请日：2007-02-13
申请人： Gina McLaren , Robert Ellis , James Douglass , Thomas Riding , James Ring
发明人： Gina McLaren , Robert Ellis , James Douglass , Thomas Riding , James Ring
IPC分类号： G06K9/00
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.
摘要翻译：提供了用于自动光学显微镜检测与细胞增殖性疾病相关的蛋白质的方法，系统和装置。

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