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1. 发明申请

US20070140540A1 Automated Detection of Objects in a Biological Sample 失效
标题翻译：生物样品中物体的自动检测
公开(公告)号：US20070140540A1
公开(公告)日：2007-06-21
申请号：US11674652
申请日：2007-02-13
申请人： Gina McLaren , Robert Ellis , James Douglass , Thomas Riding , James Ring
发明人： Gina McLaren , Robert Ellis , James Douglass , Thomas Riding , James Ring
IPC分类号： G06K9/00
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.
摘要翻译：提供了用于自动光学显微镜检测与细胞增殖性疾病相关的蛋白质的方法，系统和装置。

2. 发明申请

US20070206843A1 Method and Apparatus for Automated Image Analysis of Biological Specimens 有权
标题翻译：生物标本自动图像分析方法与装置
公开(公告)号：US20070206843A1
公开(公告)日：2007-09-06
申请号：US11685717
申请日：2007-03-13
申请人： James Douglass , Thomas Riding , James Ring , Gina McLaren , William Decker , Robert Ellis
发明人： James Douglass , Thomas Riding , James Ring , Gina McLaren , William Decker , Robert Ellis
IPC分类号： G06K9/00
CPC分类号： G06K9/3233 , G01N15/1475 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06K9/20 , G06K9/342 , G06K9/4609 , G06K9/4652 , G06T5/002 , G06T5/005 , G06T5/30 , G06T7/136 , G06T2207/10024 , G06T2207/10056 , G06T2207/20012 , G06T2207/20016 , G06T2207/30024
摘要： A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then filtered. The candidate interest pixels are morphologically processed and compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.
摘要翻译：用于生物标本的自动细胞分析的方法和装置以低倍率自动扫描以获取被分析以确定感兴趣的候选细胞对象的图像。低倍率图像从第一颜色空间转换为第二颜色空间。然后过滤颜色空间转换的图像。候选兴趣像素被形态地处理并与斑点参数进行比较，以识别对应于与生物样本的医学诊断相关的细胞或其他结构的候选对象。存储感兴趣对象的位置坐标，并以高倍率获取候选单元对象的附加图像。

3. 发明授权

US06546123B1 Automated detection of objects in a biological sample 失效
公开(公告)号：US06546123B1
公开(公告)日：2003-04-08
申请号：US09616817
申请日：2000-07-12
申请人： Gina McLaren , Robert Ellis
发明人： Gina McLaren , Robert Ellis
IPC分类号： G06K900
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.

4. 发明授权

US07558415B2 Automated detection of objects in a biological sample 失效
标题翻译：自动检测生物样品中的物体
公开(公告)号：US07558415B2
公开(公告)日：2009-07-07
申请号：US11674652
申请日：2007-02-13
申请人： Gina McLaren , Robert Ellis , James W. Douglass , Thomas J. Riding , James E. Ring
发明人： Gina McLaren , Robert Ellis , James W. Douglass , Thomas J. Riding , James E. Ring
IPC分类号： G06K9/00
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.
摘要翻译：提供了用于自动光学显微镜检测与细胞增殖性疾病相关的蛋白质的方法，系统和装置。

5. 发明申请

US20060080181A1 System for and method of generating sales proposals and contracts 审中-公开
标题翻译：生成销售提案和合同的制度和方法
公开(公告)号：US20060080181A1
公开(公告)日：2006-04-13
申请号：US10963778
申请日：2004-10-12
申请人： Curtis Fernandes , Gina McLaren , Robert Ellis
发明人： Curtis Fernandes , Gina McLaren , Robert Ellis
IPC分类号： G06Q30/00
CPC分类号： G06Q10/10 , G06Q30/00 , G06Q30/0601
摘要： Provided is a system for and method of generating sales proposals and contracts. The system comprises a computer, including a proposal generator program, a local sales policy file, and an unspecified number of sales proposals; a second computer, including a contract generator program, a master sales policy file, and an unspecified number of sales contracts; a communication network and a customer information database. A sales policy file can be downloaded. After negotiating with a customer, the system generates a proposal, determines whether the proposal is accepted by the customer, sends the proposal to a home office, determines whether the proposal is accepted by a manager, generates a contract, and updates a customer information database.
摘要翻译：提供了一种生成销售提案和合同的系统和方法。该系统包括计算机，包括提案生成程序，本地销售策略文件和未指定数量的销售提案; 第二台计算机，包括合同生成程序，主销售策略文件和未指定数量的销售合同; 通信网络和客户信息数据库。可以下载销售政策文件。在与客户协商后，系统生成提案，确定提案是否被客户接受，将提案发送到家庭办公室，确定提案是否被管理者接受，生成合同，更新客户信息数据库。

6. 发明授权

US07177454B2 Automated detection of objects in a biological sample 有权
标题翻译：自动检测生物样品中的物体
公开(公告)号：US07177454B2
公开(公告)日：2007-02-13
申请号：US10358114
申请日：2003-02-03
申请人： Gina McLaren , Robert Ellis , James W. Douglass , Thomas J. Riding , James E. Ring
发明人： Gina McLaren , Robert Ellis , James W. Douglass , Thomas J. Riding , James E. Ring
IPC分类号： G06K9/00 , G09G5/02
CPC分类号： G01N1/312 , G01N15/1468 , G01N15/1475 , G01N2015/1472 , G01N2015/1488 , G01N2015/1497 , G02B21/244 , G02B21/367 , G06K9/00127 , G06K9/00134 , G06T7/60
摘要： A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.
摘要翻译：提供了用于自动光学显微镜检测与细胞增殖性疾病相关的蛋白质的方法，系统和装置。

7. 发明授权

US08888713B2 Safety blood collection assembly with indicator 有权
标题翻译：带指示器的安全采血组件
公开(公告)号：US08888713B2
公开(公告)日：2014-11-18
申请号：US12206299
申请日：2008-09-08
申请人： Jamieson Crawford , Robert Ellis , Bradley M. Wilkinson , Benjamin Bartfeld , C. Mark Newby , Chee Leong Alvin Tan , Jon Moh , Stanley Sim , Neville Yu Leng Chia
发明人： Jamieson Crawford , Robert Ellis , Bradley M. Wilkinson , Benjamin Bartfeld , C. Mark Newby , Chee Leong Alvin Tan , Jon Moh , Stanley Sim , Neville Yu Leng Chia
IPC分类号： A61B5/00 , B65D81/00 , A61B5/15 , A61M5/32 , A61M5/50
CPC分类号： A61B5/1535 , A61B5/1422 , A61B5/1444 , A61B5/15003 , A61B5/150213 , A61B5/150259 , A61B5/150389 , A61B5/150496 , A61B5/150572 , A61B5/150587 , A61B5/150603 , A61B5/150641 , A61B5/150656 , A61B5/150671 , A61B5/150717 , A61B5/150732 , A61B5/1545 , A61M5/3202 , A61M5/3216 , A61M5/5086 , A61M2005/3217
摘要： A blood collection assembly includes a housing and a cannula extending distally from the housing including a patient end, and a cannula shield removably engaged with a portion of the housing. The cannula shield is capable of shielding at least the patient end of the cannula, and includes a safety shield engagement. The assembly includes a pivoting safety shield engaged with a portion of the housing, which is transitionable from a retracted position in which the patient end of the cannula is exposed, to an extended position in which the patient end of the cannula is shielded by at least a portion of the safety shield. The safety shield includes at least one locking tab releasably engageable with the safety shield engagement, wherein the locking tab is fixedly engageable with a portion of the housing in the extended position.
摘要翻译：采血组件包括壳体和从壳体向远侧延伸的套管，包括患者端，以及可拆卸地与壳体的一部分接合的套管屏蔽。插管屏蔽能够至少屏蔽插管的患者端，并且包括安全屏蔽接合。该组件包括与壳体的一部分接合的枢转安全护罩，其可从套管的患者端露出的缩回位置转换到其中插管的患者端至少被屏蔽的延伸位置安全护罩的一部分。安全护罩包括可释放地与安全屏蔽接合部接合的至少一个锁定突舌，其中锁定突出部可在伸出位置与壳体的一部分牢固地接合。

8. 发明授权

US08548633B2 Battery pack control circuit for handheld battery operated device 有权
标题翻译：手持电池供电装置的电池组控制电路
公开(公告)号：US08548633B2
公开(公告)日：2013-10-01
申请号：US12956990
申请日：2010-11-30
申请人： Paul Adams , Robert Ellis , James Newton
发明人： Paul Adams , Robert Ellis , James Newton
IPC分类号： G05D3/12
CPC分类号： F21V29/70 , F21L4/005 , H01M10/052 , H01M10/345 , H01M10/425 , H01M10/48
摘要： A heat sink for a handheld device is formed as a one piece chassis for supporting heat-producing circuits inside the device while having heat radiating surfaces outside the device. In another embodiment a battery pack control circuit under microprocessor control allows battery packs having different battery chemistries and characteristics to be interchanged in the same device without switches or adapters. Control of operating modes of the device despite changes in the battery pack including battery chemistry, state of charge, available voltage, or desired operating mode are automatic. The microprocessor measures the battery pack characteristics, using look up tables in a suitable program to adjust the circuit operating modes. The microprocessor also responds to sequential switch contact closures in setting operating modes.
摘要翻译：用于手持设备的散热器形成为一体式底架，用于在设备内部具有热辐射表面的同时支撑设备内部的发热电路。在另一个实施例中，微处理器控制下的电池组控制电路允许具有不同电池化学性质和特性的电池组在没有开关或适配器的同一装置中互换。尽管包括电池化学，充电状态，可用电压或所需的操作模式在内的电池组发生变化，但是控制器件的工作模式是自动的。微处理器测量电池组特性，使用适当程序中的查找表来调整电路工作模式。在设置工作模式时，微处理器还会响应顺序开关触点闭合。

9. 发明申请

US20100211402A1 Clinical Guidelines Engine 有权
标题翻译：临床指南引擎
公开(公告)号：US20100211402A1
公开(公告)日：2010-08-19
申请号：US12377301
申请日：2008-01-03
申请人： Timothy Eggena , Bryan Rosenberger , Robert Hale , Robert Nary , Robert Ellis , Patrick Cline
发明人： Timothy Eggena , Bryan Rosenberger , Robert Hale , Robert Nary , Robert Ellis , Patrick Cline
IPC分类号： G06Q10/00 , G06Q50/00 , G06F3/048
CPC分类号： G06F19/327 , G06F19/00 , G06Q10/10 , G06Q50/22 , G16H40/20
摘要： A medical guideline integration engine is presented. The engine imports medical guideline information from disparate sources based on various guideline standards into a knowledge base. The knowledge base houses the information in a database. Upon request, the engine retrieves the information from the knowledge base and converts the information into a desired guideline format.
摘要翻译：介绍了医疗指南整合引擎。引擎根据各种指导标准将不同来源的医疗指南信息输入知识库。知识库将信息存储在数据库中。根据请求，引擎从知识库中检索信息，并将信息转换成所需的准则格式。

10. 发明授权

US07682565B2 Assay apparatus and method using microfluidic arrays 有权
标题翻译：使用微流控阵列的测定装置和方法
公开(公告)号：US07682565B2
公开(公告)日：2010-03-23
申请号：US10744580
申请日：2003-12-22
申请人： John Linton , Karl Yoder , Robert Hess , Leila Hasan , Robert Ellis , Tanya S. Kanigan , Kristine Friesen , Arrin Katz , Colin Brenan , Tom Morrison , Javier Garcia
发明人： John Linton , Karl Yoder , Robert Hess , Leila Hasan , Robert Ellis , Tanya S. Kanigan , Kristine Friesen , Arrin Katz , Colin Brenan , Tom Morrison , Javier Garcia
IPC分类号： G01N31/22 , G01N21/01 , G01N21/77
CPC分类号： C12Q1/6858 , B01L3/5025 , B01L3/5027 , B01L3/508 , B01L3/50853 , B01L3/50857 , B01L7/52 , B01L2200/16 , B01L2300/021 , B01L2300/0609 , B01L2300/0636 , B01L2300/0819 , B01L2300/0829 , B01L2300/16 , B01L2300/1822 , B01L2300/1838 , G01N21/03 , G01N21/15 , G01N21/253 , G01N2021/0346 , G01N2021/056 , G01N2021/158 , Y10T436/11 , Y10T436/25 , Y10T436/2575
摘要： A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.
摘要翻译：用于容纳至少一个样品和试剂用于分析的系统。该系统包括一对平行的盖，其至少一个是透光的，其中一对透光盖形成顶部，并且其中一对形成底部。框架设置在盖之间，以相对于盖限定内部空间。框架和盖子彼此相关联以形成壳体，该壳体基本上与液体紧密。微流体阵列设置在内部体积中。阵列包括具有一对相对表面的厚度的材料片，以及穿过表面之间的厚度的多个通孔，通孔包含至少一个样品和试剂。

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