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1. 发明申请

US20070188746A1 OPTICAL SUBSTRATE FOR ENHANCED DETECTABILITY OF FLUORESCENCE 有权
标题翻译：用于增强荧光检测性能的光学基材
公开(公告)号：US20070188746A1
公开(公告)日：2007-08-16
申请号：US11739914
申请日：2007-04-25
申请人： Jorg Kraus , Johannes Edlinger , Max Wiki , Heidi Thome-Forster , Claus Heine-Kempkens , Bernd Maisenhoelder , Martin Kaspar
发明人： Jorg Kraus , Johannes Edlinger , Max Wiki , Heidi Thome-Forster , Claus Heine-Kempkens , Bernd Maisenhoelder , Martin Kaspar
IPC分类号： G01N21/01 , G01N21/64
CPC分类号： G02B5/285 , G01N21/0303 , G01N21/6452
摘要： A sample substrate adapted for use with fluorescence excitation light with a first wavelength. A reflector is disposed on a base. The reflector includes a reflecting multilayer interference coating with at least two layers. Not all of the layers L fulfill a quarterwave condition: dL·nL=(2N+1)·¼ wherein dL is a physical thickness of layer L, nL is an index of refraction of layer L at the first wavelength, N is an integer equal to or greater than zero and 1 is the first wavelength. Thicknesses of the layers ensure that any fluorescent sample material disposed on top of said multilayer interference coating would be located near an antinode of a standing wave formed by the excitation light with the first wavelength incident on said substrate.
摘要翻译：适用于具有第一波长的荧光激发光的样品基底。反射器设置在基座上。反射器包括具有至少两层的反射多层干涉涂层。并不是所有层L满足四分之一波长条件：dL.nL =（2N + 1）.¼其中dL是层L的物理厚度，nL是层L在第一波长的折射率，N是整数等于或大于零，1是第一波长。层的厚度确保设置在所述多层干涉涂层顶部的任何荧光样品材料将位于由入射到所述基底上的第一波长的激发光形成的驻波的波腹附近。

2. 发明授权

US07405819B2 Optical substrate for enhanced detectability of fluorescence 有权
标题翻译：用于增强荧光检测性的光学基底
公开(公告)号：US07405819B2
公开(公告)日：2008-07-29
申请号：US11739914
申请日：2007-04-25
申请人： Jorg Kraus , Johannes Edlinger , Max Wiki , Heidi Thome-Forster , Claus Heine-Kempkens , Bernd Maisenhoelder , Martin Kaspar
发明人： Jorg Kraus , Johannes Edlinger , Max Wiki , Heidi Thome-Forster , Claus Heine-Kempkens , Bernd Maisenhoelder , Martin Kaspar
IPC分类号： G01N21/64 , G01T1/10 , G02B5/28
CPC分类号： G02B5/285 , G01N21/0303 , G01N21/6452
摘要： A sample substrate adapted for use with fluorescence excitation light with a first wavelength. A reflector is disposed on a base. The reflector includes a reflecting multilayer interference coating with at least two layers. Not all of the layers L fulfill a quarterwave condition: dL·nL=(2N+1)·¼ wherein dL is a physical thickness of layer L, nL is an index of refraction of layer L at the first wavelength, N is an integer equal to or greater than zero and 1 is the first wavelength. Thicknesses of the layers ensure that any fluorescent sample material disposed on top of said multilayer interference coating would be located near an antinode of a standing wave formed by the excitation light with the first wavelength incident on said substrate.
摘要翻译：适用于具有第一波长的荧光激发光的样品基底。反射器设置在基座上。反射器包括具有至少两层的反射多层干涉涂层。并不是所有层L满足四分之一波长条件：dL.nL =（2N + 1）.¼其中dL是层L的物理厚度，nL是层L在第一波长的折射率，N是整数等于或大于零，1是第一波长。层的厚度确保设置在所述多层干涉涂层顶部的任何荧光样品材料将位于由入射到所述基底上的第一波长的激发光形成的驻波的波腹附近。

3. 发明授权

US07227633B2 Optical substrate for enhanced detectability of fluorescence 有权
标题翻译：用于增强荧光检测性的光学基底
公开(公告)号：US07227633B2
公开(公告)日：2007-06-05
申请号：US10858792
申请日：2004-06-02
申请人： Jörg Kraus , Johannes Edlinger , Max Wiki , Heidi Thome-Forster , Claus Heine-Kempkens , Bernd Maisenhoelder , Martin Kaspar
发明人： Jörg Kraus , Johannes Edlinger , Max Wiki , Heidi Thome-Forster , Claus Heine-Kempkens , Bernd Maisenhoelder , Martin Kaspar
IPC分类号： G01N21/64 , G01T1/10 , G02B5/28
CPC分类号： G02B5/285 , G01N21/0303 , G01N21/6452
摘要： A sample substrate adapted for use with fluorescence excitation light with a first wavelength. A reflector is disposed on a base. The reflector includes a reflecting multilayer interference coating with at least two layers. Not all of the layers L fulfill a quarterwave condition: dL·nL=(2N+1)·1/4 wherein dL is a physical thickness of layer L, nL is an index of refraction of layer L at the first wavelength, N is an integer equal to or greater than zero and 1 is the first wavelength. Thicknesses of the layers ensure that any fluorescent sample material disposed on top of said multilayer interference coating would be located near an antinode of a standing wave formed by the excitation light with the first wavelength incident on said substrate.
摘要翻译：适用于具有第一波长的荧光激发光的样品基底。反射器设置在基座上。反射器包括具有至少两层的反射多层干涉涂层。并不是所有层L满足四分之一波长条件：dL.nL =（2N + 1）.1 / 4其中dL是层L的物理厚度，nL是第一波长的层L的折射率，N是等于或大于零的整数，第一波长为1。层的厚度确保设置在所述多层干涉涂层顶部的任何荧光样品材料将位于由入射到所述基底上的第一波长的激发光形成的驻波的波腹附近。

4. 发明授权

US06961490B2 Waveguide plate and process for its production and microtitre plate 失效
标题翻译：波导板及其生产工艺及微量滴定板
公开(公告)号：US06961490B2
公开(公告)日：2005-11-01
申请号：US09916114
申请日：2001-07-27
申请人： Bernd Maisenhoelder , Johannes Edlinger , Claus Heine-Kempkens , Michael Pawlak , Gert Duveneck
发明人： Bernd Maisenhoelder , Johannes Edlinger , Claus Heine-Kempkens , Michael Pawlak , Gert Duveneck
IPC分类号： G01N21/55 , G01N21/77 , G02B6/12 , G02B6/124 , G02B6/34
CPC分类号： G01N21/7743 , G01N21/552 , G01N21/648 , G02B6/124 , G02B6/136 , G02B6/34 , G02B2006/12107 , G02B2006/12147
摘要： A waveguide plate and a process for making the waveguide plate with a plate-like glass substrate (1), carrying a waveguiding layer (2), with at least one coupling grating on the surface carrying said waveguiding layer (2), which coupling grating is formed as a grating of lines with a period between 150 nm and 1000 nm, the extension of said grating being at least 5 cm with lines parallel to one another, wherein the coupling angle () varies by not more than 0.1_/cm along a line of said grating and wherein the absolute value of the deviation of the coupling angle () on said waveguide plate, from a predefined desired value, does not exceed 0.5_. The deviation from the average value of the coupling angle does not exceed 0.3_, preferably not 0.15_ on the whole waveguide plate. The waveguide plate is suitable as part of a sensor platform and of an arrangement of sample compartments for chemo-and bioanalytical investigations in order to produce a coupling grating formed as a line grating with a grating period between 100 nm and 2500 nm
摘要翻译：波导板和用于制造具有板状玻璃基板（1）的波导板的工艺，其在承载所述波导层（2）的表面上具有带有至少一个耦合光栅的波导层（2），该耦合光栅形成为具有150nm至1000nm之间的周期的线的光栅，所述光栅的延伸至少5cm，线彼此平行，其中耦合角（）沿着所述光栅的直线比0.1_ / cm，并且其中耦合角度的偏差的绝对值（）在预定的期望值上不超过0.5_。在整个波导板上与耦合角的平均值的偏差不超过0.3_，最好不超过0.15_。波导板适合作为传感器平台的一部分和用于化学和生物分析研究的样品室的布置的一部分，以便产生形成为具有在100nm和2500nm之间的光栅周期的线光栅的耦合光栅

5. 发明申请

US20060008206A1 Waveguide plate and process for its production and microtitre plate 有权
标题翻译：波导板及其生产工艺及微量滴定板
公开(公告)号：US20060008206A1
公开(公告)日：2006-01-12
申请号：US11208765
申请日：2005-08-23
申请人： Bernd Maisenhoelder , Johannes Edlinger , Claus Heine-Kempkens , Michael Pawlak , Gert Duveneck
发明人： Bernd Maisenhoelder , Johannes Edlinger , Claus Heine-Kempkens , Michael Pawlak , Gert Duveneck
IPC分类号： G02B6/34
CPC分类号： G01N21/7743 , G01N21/552 , G01N21/648 , G02B6/124 , G02B6/136 , G02B6/34 , G02B2006/12107 , G02B2006/12147
摘要： A waveguide plate and a process for making the waveguide plate with a plate-like glass substrate (1), carrying a waveguiding layer (2), with at least one coupling grating on the surface carrying said waveguiding layer (2), which coupling grating is formed as a grating of lines with a period between 150 nm and 1000 nm, the extension of said grating being at least 5 cm with lines parallel to one another, wherein the coupling angle (θ) varies by not more than 0.1°/cm along a line of said grating and wherein the absolute value of the deviation of the coupling angle (θ) on said waveguide plate, from a predefined desired value, does not exceed 0.5°. The deviation from the average value of the coupling angle does not exceed 0.3°, preferably not 0.15° on the whole waveguide plate. The waveguide plate is suitable as part of a sensor platform and of an arrangement of sample compartments for chemo-and bioanalytical investigations in order to produce a coupling grating formed as a line grating with a grating period between 100 nm and 2500 nm.
摘要翻译：波导板和用于制造具有板状玻璃基板（1）的波导板的工艺，其在承载所述波导层（2）的表面上具有带有至少一个耦合光栅的波导层（2），该耦合光栅形成为具有150nm和1000nm之间的周期的线的光栅，所述光栅的延伸至少5cm，线彼此平行，其中耦合角（θ）变化不超过0.1°/ cm 沿着所述光栅的线，并且其中所述波导板上的耦合角（θ）与预定的期望值的偏差的绝对值不超过0.5°。与整个波导板的耦合角度的平均值的偏差不超过0.3°，最好不超过0.15°。波导板适合作为传感器平台的一部分和用于化学和生物分析研究的样品室的布置的一部分，以便产生形成为具有在100nm和2500nm之间的光栅周期的线光栅的耦合光栅。

6. 发明申请

US20070014017A1 METHOD FOR GENERATING ELECTROMAGNETIC FIELD DISTRIBUTIONS 审中-公开
标题翻译：用于生成电磁场分布的方法
公开(公告)号：US20070014017A1
公开(公告)日：2007-01-18
申请号：US11462819
申请日：2006-08-07
申请人： Heidi Thome-Forster , Claus Heine-Kempkens
发明人： Heidi Thome-Forster , Claus Heine-Kempkens
IPC分类号： G02B5/18
CPC分类号： G01N21/6452 , G01N21/4788 , G01N21/774 , G01N21/7746
摘要： This invention relates to a platform (11) and a method for generating electromagnetic field distributions. The invention relates in particular to optical sensors for measuring biological or chemical substances. The platform (11) according to the invention comprises a substrate (13), a structured layer (19) and, positioned between the substrate (13) and the structured layer (19), a multilayer assembly (17), said components being so matched relative to one another that upon appropriate impingement by electromagnetic radiation an electromagnetic field distribution is generated that is at a maximum within the structured layer (19).
摘要翻译：本发明涉及平台（11）和产生电磁场分布的方法。本发明特别涉及用于测量生物或化学物质的光学传感器。根据本发明的平台（11）包括衬底（13），结构化层（19），并且位于衬底（13）和结构化层（19）之间，多层组件（17），所述组件如此相对于彼此匹配，在通过电磁辐射适当冲击时，产生在结构化层（19）内处于最大值的电磁场分布。

7. 发明授权

US07057822B2 System for projecting an image using narrow band light sources 有权
公开(公告)号：US07057822B2
公开(公告)日：2006-06-06
申请号：US10369374
申请日：2003-02-19
申请人： Johannes Edlinger , Claus Heine-Kempkens
发明人： Johannes Edlinger , Claus Heine-Kempkens
IPC分类号： G02B27/10
CPC分类号： G02B27/1086 , G02B27/1026 , G02B27/145 , H04N9/3164 , H04N9/3167
摘要： The invention provides an image projection system including a first light source and a second light source. Light from the first light source is limited to a finite number of limited wavelength intervals. An imaging device is adapted for modulating light from the first and second light sources. A beam combiner is provided to combine light from the light sources and direct the combined light to the imaging device. Modulated light from the imaging device is directed to a lens.

8. 发明授权

US07026046B2 Component comprising submicron hollow spaces 失效
标题翻译：组件包括亚微米空心空间
公开(公告)号：US07026046B2
公开(公告)日：2006-04-11
申请号：US11104186
申请日：2005-04-12
申请人： Johannes Edlinger , Claus Heine-Kempkens , Othmar Züger
发明人： Johannes Edlinger , Claus Heine-Kempkens , Othmar Züger
IPC分类号： B32B5/14 , B32B3/26 , G02B27/28 , C23C16/00
CPC分类号： G02B1/118 , B01D21/0012 , B01D39/2051 , B01L3/502707 , B01L3/50273 , B01L3/502753 , B01L3/502761 , B01L3/502792 , B01L2200/0647 , B01L2200/0668 , B01L2200/141 , B01L2300/0681 , B01L2300/0816 , B01L2300/0825 , B01L2300/16 , B01L2400/0406 , B01L2400/0409 , B01L2400/086 , B81B1/002 , B81B2201/047 , B81B2201/10 , B81B2203/0338 , B81C1/00119 , C23C14/04 , C23C14/046 , G02B5/1809 , G02B5/1847 , G02B5/3058 , G02B5/3083 , G02B2006/12097 , Y10S428/913 , Y10T428/24612 , Y10T428/24942 , Y10T428/249953 , Y10T428/249961 , Y10T428/249975 , Y10T428/249977 , Y10T428/249979 , Y10T428/24998 , Y10T428/31678 , Y10T436/111666 , Y10T436/112499 , Y10T436/25375 , Y10T436/255
摘要： An optical component or an analytical platform includes a substrate, an array of microstructures on the substrate and microchannels formed by side walls of adjacent microstructures, a width of the microchannels varies as a function of distance to the substrate, the width continuously decreasing with increasing distance from the substrate within at least one distance-interval. In a method for producing such a component or such a platform a substrate with an array of surface microstructures is coated in a vapor treatment in such a way that shadowing effects of the coating mechanism narrow at least partially a width of the upper parts of side walls of the microstructures thereby forming at least partially embedded microchannels.
摘要翻译：光学部件或分析平台包括基板，基板上的微结构阵列和由相邻微结构的侧壁形成的微通道，微通道的宽度随着距衬底的距离而变化，宽度随着距离的增加而连续减小在至少一个距离间隔内的衬底。在用于制造这种部件或这种平台的方法中，具有表面微结构阵列的基板以蒸气处理方式被涂覆，使得涂覆机构的遮蔽效应至少部分地缩小了侧壁上部的宽度从而形成至少部分嵌入的微通道。

9. 发明授权

US06884500B2 Component comprising submicron hollow spaces 失效
公开(公告)号：US06884500B2
公开(公告)日：2005-04-26
申请号：US10366095
申请日：2003-02-12
申请人： Johannes Edlinger , Claus Heine-Kempkens , Othmar Züger
发明人： Johannes Edlinger , Claus Heine-Kempkens , Othmar Züger
IPC分类号： B01D21/00 , B01D39/20 , B01L3/00 , B81B1/00 , C23C14/04 , G02B5/18 , G02B5/30 , G02B6/12 , B32B5/14 , B32B3/26 , G02B5/20
CPC分类号： G02B1/118 , B01D21/0012 , B01D39/2051 , B01L3/502707 , B01L3/50273 , B01L3/502753 , B01L3/502761 , B01L3/502792 , B01L2200/0647 , B01L2200/0668 , B01L2200/141 , B01L2300/0681 , B01L2300/0816 , B01L2300/0825 , B01L2300/16 , B01L2400/0406 , B01L2400/0409 , B01L2400/086 , B81B1/002 , B81B2201/047 , B81B2201/10 , B81B2203/0338 , B81C1/00119 , C23C14/04 , C23C14/046 , G02B5/1809 , G02B5/1847 , G02B5/3058 , G02B5/3083 , G02B2006/12097 , Y10S428/913 , Y10T428/24612 , Y10T428/24942 , Y10T428/249953 , Y10T428/249961 , Y10T428/249975 , Y10T428/249977 , Y10T428/249979 , Y10T428/24998 , Y10T428/31678 , Y10T436/111666 , Y10T436/112499 , Y10T436/25375 , Y10T436/255
摘要： An optical component or an analytical platform includes a substrate, an array of microstructures on the substrate and microchannels formed by side walls of adjacent microstructures, a width of the microchannels varies as a function of distance to the substrate, the width continuously decreasing with increasing distance from the substrate within at least one distance-interval. In a method for producing such a component or such a platform a substrate with an array of surface microstructures is coated in a vapor treatment in such a way that shadowing effects of the coating mechanism narrow at least partially a width of the upper parts of side walls of the microstructures thereby forming at least partially embedded microchannels.

10. 发明申请

US20060147679A1 Component comprising submicron hollow spaces 有权
公开(公告)号：US20060147679A1
公开(公告)日：2006-07-06
申请号：US11368813
申请日：2006-03-06
申请人： Johannes Edlinger , Claus Heine-Kempkens , Othmar Zuger
发明人： Johannes Edlinger , Claus Heine-Kempkens , Othmar Zuger
IPC分类号： B32B3/00
CPC分类号： G02B1/118 , B01D21/0012 , B01D39/2051 , B01L3/502707 , B01L3/50273 , B01L3/502753 , B01L3/502761 , B01L3/502792 , B01L2200/0647 , B01L2200/0668 , B01L2200/141 , B01L2300/0681 , B01L2300/0816 , B01L2300/0825 , B01L2300/16 , B01L2400/0406 , B01L2400/0409 , B01L2400/086 , B81B1/002 , B81B2201/047 , B81B2201/10 , B81B2203/0338 , B81C1/00119 , C23C14/04 , C23C14/046 , G02B5/1809 , G02B5/1847 , G02B5/3058 , G02B5/3083 , G02B2006/12097 , Y10S428/913 , Y10T428/24612 , Y10T428/24942 , Y10T428/249953 , Y10T428/249961 , Y10T428/249975 , Y10T428/249977 , Y10T428/249979 , Y10T428/24998 , Y10T428/31678 , Y10T436/111666 , Y10T436/112499 , Y10T436/25375 , Y10T436/255
摘要： An optical component or an analytical platform includes a substrate, an array of microstructures on the substrate and microchannels formed by side walls of adjacent microstructures, a width of the microchannels varies as a function of distance to the substrate, the width continuously decreasing with increasing distance from the substrate within at least one distance-interval. In a method for producing such a component or such a platform a substrate with an array of surface microstructures is coated in a vapor treatment in such a way that shadowing effects of the coating mechanism narrow at least partially a width of the upper parts of side walls of the microstructures thereby forming at least partially embedded microchannels.

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