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1. 发明申请

US20060145098A1 Real-time monitoring apparatus for biochemical reaction 有权
标题翻译：生化反应实时监测仪
公开(公告)号：US20060145098A1
公开(公告)日：2006-07-06
申请号：US10551784
申请日：2004-04-03
申请人： Jong-Soo Baek , Dong-Yeon Cho , Hanee Park , Han-Oh Park
发明人： Jong-Soo Baek , Dong-Yeon Cho , Hanee Park , Han-Oh Park
IPC分类号： G21G4/00
CPC分类号： G01N21/0332 , B01L7/52 , G01N21/6452 , G01N2021/6484
摘要： The present invention relates to an apparatus for real-time monitoring chemical reaction between various biomaterials. More particularly, the present invention directed to a real-time monitoring apparatus for biochemical reaction, which comprises parabolic mirror and/or an optical waveguide tube for effective irradiation of light over the whole plate with uniform intensity.
摘要翻译：本发明涉及一种用于实时监测各种生物材料之间的化学反应的装置。更具体地说，本发明涉及一种用于生物化学反应的实时监测装置，其包括抛物面反射镜和/或光波导管，用于以均匀的强度在整个板上有效地照射光。

2. 发明授权

US08139210B2 Real-time monitoring apparatus for biochemical reaction 有权
标题翻译：生化反应实时监测仪
公开(公告)号：US08139210B2
公开(公告)日：2012-03-20
申请号：US10551784
申请日：2004-04-03
申请人： Jong-Soo Baek , Dong-Yeon Cho , Hanee Park , Han-Oh Park
发明人： Jong-Soo Baek , Dong-Yeon Cho , Hanee Park , Han-Oh Park
IPC分类号： G01J3/00
CPC分类号： G01N21/0332 , B01L7/52 , G01N21/6452 , G01N2021/6484
摘要： The present invention relates to an apparatus for real-time monitoring chemical reaction between various biomaterials. More particularly, the present invention directed to a real-time monitoring apparatus for biochemical reaction, which comprises parabolic mirror and/or an optical waveguide tube for effective irradiation of light over the whole plate with uniform intensity.
摘要翻译：本发明涉及一种用于实时监测各种生物材料之间的化学反应的装置。更具体地说，本发明涉及一种用于生物化学反应的实时监测装置，其包括抛物面反射镜和/或光波导管，用于以均匀的强度在整个板上有效地照射光。

3. 发明授权

US08329106B2 Miniaturized apparatus for real-time monitoring 有权
标题翻译：用于实时监控的小型化设备
公开(公告)号：US08329106B2
公开(公告)日：2012-12-11
申请号：US11661410
申请日：2005-09-01
申请人： Han Oh Park , Hanee Park , Jong Soo Baek
发明人： Han Oh Park , Hanee Park , Jong Soo Baek
IPC分类号： G01N21/64 , B01J19/00
CPC分类号： G01N21/645 , B01L3/5025 , B01L7/525 , B01L2300/0838 , B01L2300/0841 , B01L2300/087
摘要： The present invention relates to a apparatus for quantitative continuous real-time monitoring to monitor a continuous reaction of biochemical reagent and the reaction, such as DNA. More particularly, the present invention is directed to a miniaturized apparatus for real-time monitoring of biochemical reaction, which comprises capillary tubes (100) wherein biochemical reaction mixture flow; a thermal conduction block (120) which is coiled with capillary tube several rounds in order and composed of several blocks for temperature control of which temperatures are different from each other for heating or cooling the biochemical reaction mixture which flow in capillary tube, and a temperature controller which controls the temperature of above temperature control block; a radiation part (130) to radiate the reaction mixture flowing through the capillary tube and a light receiving section (140) which receives and measures the intensity of the fluorescence generated from the capillary tubes.
摘要翻译：本发明涉及用于定量连续实时监测的装置，用于监测生物化学试剂和反应如DNA的连续反应。更具体地，本发明涉及一种用于实时监测生物化学反应的小型化装置，其包括其中生物化学反应混合物流动的毛细管（100）热传导块（120），其顺序地由毛细管螺旋成几圈，并且由用于温度彼此不同的温度控制的几个块组成，用于加热或冷却在毛细管中流动的生物化学反应混合物，温度控制器控制上述温度控制块的温度; 用于辐射流过毛细管的反应混合物的辐射部分（130）和接收并测量从毛细管产生的荧光强度的光接收部分（140）。

4. 发明授权

US09205425B2 Thermal cycling reaction block and continuous real-time monitoring apparatus using the same 有权
标题翻译：热循环反应块和使用其的连续实时监测装置
公开(公告)号：US09205425B2
公开(公告)日：2015-12-08
申请号：US12999696
申请日：2009-06-23
申请人： Han Oh Park , Hanee Park , Il Kyu Choi
发明人： Han Oh Park , Hanee Park , Il Kyu Choi
IPC分类号： B01L7/00 , B01L3/00 , G01N21/64
CPC分类号： B01L7/525 , B01L2300/0838 , B01L2300/0861 , B01L2300/1805 , G01N21/64 , G01N2021/6467
摘要： Disclosed is real-time monitoring apparatus comprising a thermal cycling reaction block having heating block which is formed of a hollow part and divided by an insulating layer, and a capillary tube through which a sample is flowed in and/or out and which is wound on the heating block so that the different temperatures are transferred and thus reaction cycle is repeatedly performed; a light source; a band pass filter; a condensing lens; a beam splitter; a reflecting mirror which is rotatably connected with a motor so as to transfer the excitation light reflected from the beam splitter to the capillary tube and reflect the fluorescence generated from the sample in the capillary tube; and a fluorescence detecting part.
摘要翻译：公开了一种实时监测装置，其包括具有加热块的热循环反应块，该加热块由中空部分形成并被绝缘层分开，毛细管通过该毛细管将样品流入和/或流出并且被卷绕在其上加热块，以便转移不同的温度，从而反复进行反应循环; 光源; 带通滤波器; 聚光透镜; 分束器; 反射镜，其与电动机可旋转地连接，以将从分束器反射的激发光转移到毛细管，并将从样品产生的荧光反射到毛细管中; 和荧光检测部。

5. 发明授权

US08427643B2 Real-time PCR monitoring apparatus 有权
标题翻译：实时PCR监测仪
公开(公告)号：US08427643B2
公开(公告)日：2013-04-23
申请号：US12598061
申请日：2008-06-17
申请人： Hanee Park , Il kyu Choi , Han Oh Park
发明人： Hanee Park , Il kyu Choi , Han Oh Park
IPC分类号： G01J4/00
CPC分类号： G01N21/6445 , G01J3/0224 , G01J3/4406 , G01N21/6452 , G01N2021/6478 , G01N2021/6484 , G01N2201/0631 , G01N2201/0636
摘要： The present invention relates to a real-time PCR monitoring apparatus for real-time monitoring production of reaction product produced during the reaction while performing nucleic acid amplification such as PCR for various kinds of trace samples. Specifically, the present invention relates to an apparatus for real-time monitoring biochemical reaction for efficiently dividing interference between an excitation light and a fluorescence, which includes a polarizer, a polarizing beam splitter, a polarization converter and so on.
摘要翻译：本发明涉及一种用于实时监测在反应过程中产生的反应产物的实时PCR监测装置，同时对各种痕量样品进行核酸扩增如PCR。具体地说，本发明涉及一种用于实时监测生化反应的装置，用于有效地分离激发光和荧光之间的干扰，其包括偏振器，偏振分束器，偏振转换器等。

6. 发明申请

US20110159579A1 THERMAL CYCLING REACTION BLOCK AND CONTINUOUS REAL-TIME MONITORING APPARATUS USING THE SAME 有权
标题翻译：热循环反应块和连续实时监测装置
公开(公告)号：US20110159579A1
公开(公告)日：2011-06-30
申请号：US12999696
申请日：2009-06-23
申请人： Han Oh Park , Hanee Park , Il Kyu Choi
发明人： Han Oh Park , Hanee Park , Il Kyu Choi
IPC分类号： C12M1/00
CPC分类号： B01L7/525 , B01L2300/0838 , B01L2300/0861 , B01L2300/1805 , G01N21/64 , G01N2021/6467
摘要： Disclosed is real-time monitoring apparatus comprising a thermal cycling reaction block having heating block which is formed of a hollow part and divided by an insulating layer, and a capillary tube through which a sample is flowed in and/or out and which is wound on the heating block so that the different temperatures are transferred and thus reaction cycle is repeatedly performed; a light source; a band pass filter; a condensing lens; a beam splitter; a reflecting mirror which is rotatably connected with a motor so as to transfer the excitation light reflected from the beam splitter to the capillary tube and reflect the fluorescence generated from the sample in the capillary tube; and a fluorescence detecting part.
摘要翻译：公开了一种实时监测装置，其包括具有加热块的热循环反应块，该加热块由中空部分形成并被绝缘层分开，毛细管通过该毛细管将样品流入和/或流出并且被卷绕在其上加热块，以便转移不同的温度，从而反复进行反应循环; 光源; 带通滤波器; 聚光透镜; 分束器; 反射镜，其与电动机可旋转地连接，以将从分束器反射的激发光转移到毛细管，并将从样品产生的荧光反射到毛细管中; 和荧光检测部。

7. 发明申请

US20100085570A1 REAL-TIME PCR MONITORING APPARATUS 有权
标题翻译：实时PCR监测装置
公开(公告)号：US20100085570A1
公开(公告)日：2010-04-08
申请号：US12598061
申请日：2008-06-17
申请人： Hanee Park , Il Kyu Choi , Han Oh Park
发明人： Hanee Park , Il Kyu Choi , Han Oh Park
IPC分类号： G01N21/64 , G01J1/58
CPC分类号： G01N21/6445 , G01J3/0224 , G01J3/4406 , G01N21/6452 , G01N2021/6478 , G01N2021/6484 , G01N2201/0631 , G01N2201/0636
摘要： The present invention relates to a real-time PCR monitoring apparatus for real-time monitoring production of reaction product produced during the reaction while performing nucleic acid amplification such as PCR for various kinds of trace samples. Specifically, the present invention relates to an apparatus for real-time monitoring biochemical reaction for efficiently dividing interference between an excitation light and a fluorescence, which includes a polarizer, a polarizing beam splitter, a polarization converter and so on.
摘要翻译：本发明涉及一种用于实时监测在反应过程中产生的反应产物的实时PCR监测装置，同时对各种痕量样品进行核酸扩增如PCR。具体地说，本发明涉及一种用于实时监测生化反应的装置，用于有效地分离激发光和荧光之间的干扰，其包括偏振器，偏振分束器，偏振转换器等。

8. 发明授权

US06436698B2 Apparatus for automatic measuring of water toxicity 失效
标题翻译：用于自动测量水毒性的装置
公开(公告)号：US06436698B2
公开(公告)日：2002-08-20
申请号：US09761654
申请日：2001-01-18
申请人： Han Oh Park , Hanee Park , Il Kyu Choi
发明人： Han Oh Park , Hanee Park , Il Kyu Choi
IPC分类号： C12M136
CPC分类号： C12Q1/02 , G01N21/763 , G01N33/1826 , G01N33/1866 , G01N2520/00 , Y02A20/206
摘要： The present invention relates to an apparatus for automatic measuring of water toxicity. More specifically, the present invention provides an apparatus for automatic and continuous measuring of water toxicity and/or contamination using luminescent microorganisms living in freshwater.
摘要翻译：本发明涉及一种用于自动测量水毒性的装置。更具体地说，本发明提供一种用于利用居住在淡水中的发光微生物自动连续地测量水毒性和/或污染的装置。

9. 发明授权

US5751122A Digital convergence correction system 失效
标题翻译：数字融合校正系统
公开(公告)号：US5751122A
公开(公告)日：1998-05-12
申请号：US583976
申请日：1996-01-11
申请人： Hanee Park
发明人： Hanee Park
IPC分类号： H04N9/28 , H01J29/62 , H04N3/22
CPC分类号： H04N9/28
摘要： Digital convergence correction system for correcting misconvergence on a screen of a multi-mode projection television, including a first memory part for storing adjustment point data for every mode of multi-modes, a second memory part for storing convergence correction data in accordance with the adjustment point data, a control part for producing the convergence correction data using the adjustment point data stored in the first memory part for writing the convergence correction data on the second memory part and outputting the convergence correction data stored in the second memory part, and a time sharing processing unit for controlling the control part to share time in producing the convergence correction data and renewing convergence correction data in the second memory part and outputting the convergence correction data stored already in the second memory part for preventing overlap of the producing and storing time and the outputting time.
摘要翻译：数字会聚校正系统，用于校正多模式投影电视的屏幕上的失会聚，包括用于存储每种模式的模式的调整点数据的第一存储器部分，用于存储根据调整的会聚校正数据的第二存储器部分点数据，用于使用存储在第一存储器部分中的调整点数据产生会聚校正数据的控制部分，用于将会聚校正数据写入第二存储器部分，并输出存储在第二存储器部分中的会聚校正数据，以及时间共享处理单元，用于控制控制部分，以共享产生会聚校正数据的时间并更新第二存储器部分中的会聚校正数据，并输出已经存储在第二存储器部分中的会聚校正数据，以防止生产和存储时间的重叠，以及输出时间。

10. 发明申请

US20080032416A1 Miniaturized Apparatus For Real-Time Monitoring 有权
标题翻译：用于实时监控的小型化设备
公开(公告)号：US20080032416A1
公开(公告)日：2008-02-07
申请号：US11661410
申请日：2005-09-01
申请人： Han Park , Hanee Park , Jong Baek
发明人： Han Park , Hanee Park , Jong Baek
IPC分类号： G01N21/64 , B01J19/00
CPC分类号： G01N21/645 , B01L3/5025 , B01L7/525 , B01L2300/0838 , B01L2300/0841 , B01L2300/087
摘要： The present invention relates to a apparatus for quantitative continuous real-time monitoring to monitor a continuous reaction of biochemical reagent and the reaction, such as DNA. More particularly, the present invention is directed to a miniaturized apparatus for real-time monitoring of biochemical reaction, which comprises capillary tubes (100) wherein biochemical reaction mixture flow; a thermal conduction block (120) which is coiled with capillary tube several rounds in order and composed of several blocks for temperature control of which temperatures are different from each other for heating or cooling the biochemical reaction mixture which flow in capillary tube, and a temperature controller which controls the temperature of above temperature control block; a radiation part (130) to radiate the reaction mixture flowing through the capillary tube and a light receiving section (140) which receives and measures the intensity of the fluorescence generated from the capillary tubes.
摘要翻译：本发明涉及用于定量连续实时监测的装置，用于监测生物化学试剂和反应如DNA的连续反应。更具体地，本发明涉及一种用于实时监测生物化学反应的小型化装置，其包括其中生物化学反应混合物流动的毛细管（100）热传导块（120），其顺序地由毛细管螺旋成几圈，并且由用于温度彼此不同的温度控制的几个块组成，用于加热或冷却在毛细管中流动的生物化学反应混合物，温度控制器控制上述温度控制块的温度; 用于辐射流过毛细管的反应混合物的辐射部分（130）和接收并测量从毛细管产生的荧光强度的光接收部分（140）。

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