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    • 2. 发明授权
    • Anti-inflammatory and antimicrobial uses for bioactive glass compositions
    • 用于生物活性玻璃组合物的抗炎和抗微生物用途
    • US06756060B1
    • 2004-06-29
    • US09560046
    • 2000-04-27
    • David C. GreenspanJon K. WestSean LeeJames L. MeyersMason Diamond
    • David C. GreenspanJon K. WestSean LeeJames L. MeyersMason Diamond
    • A61K914
    • A61Q1/02A61K8/25A61K45/06A61L15/18A61L15/44A61L15/46A61Q5/00A61Q17/005A61Q19/00C03C4/0007Y10S424/13Y10S514/829Y10S514/83Y10S514/831Y10S514/859Y10S514/861Y10S514/862Y10S514/863Y10S514/864Y10S514/886Y10S514/887Y10S514/951Y10S514/965
    • Compositions and methods for treating wounds to significantly reduce the healing time, reduce the incidence of scar formation, improve the success of skin grafts, reduce the inflammatory response and providing anti-bacterial treatments to a patient in need thereof, that include small non-interlinked particles of bioactive glass or highly porous bioactive glass, are disclosed. Anti-bacterial solutions derived from bioactive glass, and methods of preparation and use thereof, are also disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with anti-bacterial agents and/or anti-inflammatory agents. The compositions can include an appropriate carrier for topical administration. Anti-bacterial properties can be imparted to implanted materials, such as prosthetic implants, sutures, stents, screws, plates, tubes, and the like, by incorporating small bioactive glass particles or porous bioactive glass into or onto the implanted materials. Anti-bacterial properties can also be imparted to devices used for in vitro and ex vivo cell culture by incorporating non-interlinked particles of bioactive glass into the devices. Anti-bacterial compositions derived from aqueous extracts of bioactive glass are also disclosed. These compositions can be used, for example, in food preparation, solutions used for cell culture, and buffer solutions, such as i.v. solutions.
    • 用于治疗创伤以显着减少愈合时间的组合物和方法,减少瘢痕形成的发生率,改善皮肤移植物的成功,减少炎症反应并向有需要的患者提供抗菌治疗,包括小的非相互连接 公开了生物活性玻璃或高度多孔生物活性玻璃的颗粒。 还公开了衍生自生物活性玻璃的抗菌溶液及其制备和使用方法。 组合物包括单独的或与抗细菌剂和/或抗炎剂组合的生物活性玻璃的非互连颗粒。 组合物可以包括用于局部给药的合适的载体。 通过将小生物活性玻璃颗粒或多孔生物活性玻璃并入到植入的材料中,可将植物材料(例如假体植入物,缝合线,支架,螺钉,板,管等)赋予抗菌性能。 通过将非生物活性玻璃的非互连颗粒结合到装置中,也可以将抗细菌性质赋予用于体外和离体细胞培养的装置。 还公开了衍生自生物活性玻璃的水提取物的抗菌组合物。 这些组合物可用于例如食品制备,用于细胞培养的溶液和缓冲溶液,例如静脉内。 解决方案
    • 3. 发明授权
    • Multibeam side-look sonar system grating side lobe reduction technique
    • 多光束侧视声纳系统光栅旁瓣缩小技术
    • US5515337A
    • 1996-05-07
    • US425550
    • 1995-04-20
    • George A. GilmourJames L. MeyersLeslie M. James
    • George A. GilmourJames L. MeyersLeslie M. James
    • G01S7/52G01S15/89G10K11/34
    • G10K11/348G01S15/8902G01S7/52003Y10S367/905
    • A multibeam side-look sonar system includes a projecting transducer that projects a beam of acoustic energy to insonify a target area and a receiving transducer having a plurality of transducer elements arranged in a linear array. Each of the transducer elements generates a beam signal in response to acoustic energy reflected from the target area. A beamforming circuit, coupled to the receiving transducer, processes the beam signals generated by the transducer elements to form a beam pattern. The beam pattern for an end beam on the receiving transducer has a main lobe and grating side lobes. One of the grating side lobes may be insonified by the projected beam of acoustic energy. A shading circuit, coupled between the receiving transducer and the beamforming circuit, amplifies the beam signals with respective gains, and adjusts each of the respective gains to reduce an amplitude level of the grating side lobe insonified by the projected beam of acoustic energy.
    • 多光束侧视声纳系统包括投影换能器,其投影声能束以使目标区域发散,以及具有以线性阵列排列的多个换能器元件的接收换能器。 每个换能器元件响应于从目标区域反射的声能产生波束信号。 耦合到接收换能器的波束成形电路处理由换能器元件产生的波束信号以形成波束图案。 接收换能器上端束的波束图具有主瓣和光栅旁瓣。 光栅旁瓣中的一个可能被投射的声能束声强化。 耦合在接收换能器和波束形成电路之间的遮蔽电路用各自的增益来放大波束信号,并且调整相应的增益中的每一个以减小被投射的声能束声强化的光栅侧波瓣的振幅电平。