专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07004928B2 Autonomous, ambulatory analyte monitor or drug delivery device 有权
公开(公告)号：US07004928B2
公开(公告)日：2006-02-28
申请号：US10131268
申请日：2002-04-23
申请人： John Gregory Aceti , Sterling Eduard McBride , Richard Morgan Moroney, III , Christopher Carter Gregory , Peter John Zanzucchi
发明人： John Gregory Aceti , Sterling Eduard McBride , Richard Morgan Moroney, III , Christopher Carter Gregory , Peter John Zanzucchi
IPC分类号： A61M5/00 , A61M5/315 , A61B5/00 , B65D81/00
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/150022 , A61B5/150076 , A61B5/150213 , A61B5/150389 , A61B5/150503 , A61B5/150526 , A61B5/150755 , A61B5/15087 , A61B5/150969 , A61B5/15109 , A61B5/15119 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6833 , A61B2560/0412 , A61B2560/0443 , A61M37/0015 , A61M2037/0023 , A61M2037/0038 , A61M2209/088 , A61M2230/201 , G01N33/491
摘要： The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.

2. 发明授权

US06923764B2 Analyte monitor 有权
标题翻译：分析物监测仪
公开(公告)号：US06923764B2
公开(公告)日：2005-08-02
申请号：US10347620
申请日：2003-01-22
申请人： John Gregory Aceti , Zvi Gerald Loewy , Richard Morgan Moroney, III , Christopher Carter Gregory , Peter John Zanzucchi
发明人： John Gregory Aceti , Zvi Gerald Loewy , Richard Morgan Moroney, III , Christopher Carter Gregory , Peter John Zanzucchi
IPC分类号： A61B5/145 , A61B5/00 , A61B5/1459 , A61B5/15 , A61B5/151 , A61B5/157
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150229 , A61B5/150389 , A61B5/150473 , A61B5/150511 , A61B5/150755 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , G06F19/00
摘要： Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.
摘要翻译：提供了一种具有壳体的分析物监测装置，该装置包括：多个针，每个针具有尖端，缩回位置，其中尖端从壳体延伸适合于刺穿皮肤的距离; 电动或弹簧动力的推针装置，其可移动以分别接合每个针，以使其从缩回位置移动到延伸位置; 位于壳体内的能源; 多个分析位点，包括分析制剂，每个分析制剂适于从针头接收液体以润湿分析制剂; 适于在分析场所引导光的一个或多个光源; 一个或多个适于从分析位置接收光的光检测器; 和处理器。

3. 发明授权

US06540675B2 Analyte monitor 有权
公开(公告)号：US06540675B2
公开(公告)日：2003-04-01
申请号：US09741755
申请日：2000-12-20
申请人： John Gregory Aceti , Zvi Gerald Loewy , Richard Morgan Moroney, III , Christopher Carter Gregory , Peter John Zanzucchi
发明人： John Gregory Aceti , Zvi Gerald Loewy , Richard Morgan Moroney, III , Christopher Carter Gregory , Peter John Zanzucchi
IPC分类号： A61B500
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150229 , A61B5/150389 , A61B5/150473 , A61B5/150511 , A61B5/150755 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , G06F19/00
摘要： Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

4. 发明授权

US08303518B2 Autonomous, ambulatory analyte monitor or drug delivery device 有权
标题翻译：自主，动态分析物监测或药物输送装置
公开(公告)号：US08303518B2
公开(公告)日：2012-11-06
申请号：US11311667
申请日：2005-12-20
申请人： John Gregory Aceti , Sterling Eduard Mcbride , Richard Morgan Moroney , Christopher Carter Gregory , Peter John Zanzucchi
发明人： John Gregory Aceti , Sterling Eduard Mcbride , Richard Morgan Moroney , Christopher Carter Gregory , Peter John Zanzucchi
IPC分类号： A61B5/00
CPC分类号： A61B5/150984 , A61B5/1411 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/150022 , A61B5/150076 , A61B5/150213 , A61B5/150389 , A61B5/150503 , A61B5/150526 , A61B5/150755 , A61B5/15087 , A61B5/150969 , A61B5/15109 , A61B5/15119 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , A61B5/155 , A61B5/157 , A61B5/681 , A61B5/6833 , A61B2560/0412 , A61B2560/0443 , A61M37/0015 , A61M2037/0023 , A61M2037/0038 , A61M2209/088 , A61M2230/201 , G01N33/491
摘要： The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.
摘要翻译：本发明涉及分析物监测/药物（药剂）递送装置。本发明适用于监测各种血液成分如葡萄糖。该装置具有至少部分地包围设置在载体和电子部分上的多个微针的壳体。每个微针与相应的微通道流体连通。每个微针都可单独寻址。也就是说，每个微针可以通过致动器单独地延伸和缩回。电子部分包括处理器和相关联的电路（例如，存储器，支持电子设备等），电动机等，传感器，电源（例如电池）和可选的接口。通常，处理器控制设备的操作，并且与致动器，电动机，传感器和接口进行数据通信。本发明提供自主操作，即不用户干预。本发明可以任选地提供校准而不需要用户的干预。本发明还可以提供昼夜半连续监测。本发明可以提供多达四个或更多周的操作。本发明可以提供尺寸相对较小并因此不显眼的装置。本发明还可以为具有远程控制和交互式电子设备的设备提供。本发明还可以用于递送包括高效药物在内的各种药剂，以最小化患者干预并使不适程度最小化。

5. 发明授权

US07585278B2 Analyte monitor 有权
公开(公告)号：US07585278B2
公开(公告)日：2009-09-08
申请号：US10722074
申请日：2003-11-24
申请人： John Gregory Aceti , Zvi Gerald Lowey , Richard Morgan Moroney , Christopher Carter Gregory , Peter John Zanzucchi
发明人： John Gregory Aceti , Zvi Gerald Lowey , Richard Morgan Moroney , Christopher Carter Gregory , Peter John Zanzucchi
IPC分类号： A61B5/00
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150229 , A61B5/150389 , A61B5/150473 , A61B5/150511 , A61B5/150755 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , G06F19/00
摘要： Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

6. 发明授权

US06723072B2 Plunger assembly for patient infusion device 失效
标题翻译：用于患者输液装置的柱塞组件
公开(公告)号：US06723072B2
公开(公告)日：2004-04-20
申请号：US10163690
申请日：2002-06-06
申请人： J. Christopher Flaherty , Christopher Carter Gregory , Derek Dwayne Mahoney , John Michael Margicin
发明人： J. Christopher Flaherty , Christopher Carter Gregory , Derek Dwayne Mahoney , John Michael Margicin
IPC分类号： A61M3100
CPC分类号： A61M5/1452 , A61M5/14248 , A61M5/16809 , A61M5/31511 , A61M2205/0266
摘要： A device for delivering fluid, such as insulin, to a patient. The device includes an exit port assembly, a syringe-like reservoir including a side wall extending along a longitudinal axis towards an outlet connected to the exit port assembly, and a plunger assembly received in the reservoir. The plunger assembly includes a two-way shape memory element connecting first and second lateral segments, and having a changeable length decreasing from an uncharged length to a charged length when at least one charge is applied to the shape memory element. Successively applying a charge and removing the charge from the two-way shape memory element causes longitudinal movement of the plunger assembly towards the outlet of the reservoir in order to cause fluid to be dispensed from the reservoir to the exit port assembly.
摘要翻译：用于向患者输送诸如胰岛素的流体的装置。该装置包括出口端口组件，注射器状容器，其包括沿着纵向轴线朝连接到出口端口组件的出口延伸的侧壁以及容纳在容器中的柱塞组件。柱塞组件包括连接第一和第二横向段的双向形状记忆元件，并且当至少一个电荷施加到形状记忆元件时，具有从不带电长度减小到带电长度的可变长度。连续地施加电荷并从双向形状记忆元件去除电荷导致柱塞组件朝向储存器的出口的纵向运动，以便使流体从储存器分配到出口端口组件。

7. 发明授权

US06656158B2 Dispenser for patient infusion device 失效
标题翻译：用于患者输液装置的分配器
公开(公告)号：US06656158B2
公开(公告)日：2003-12-02
申请号：US10128203
申请日：2002-04-23
申请人： Derek Dwayne Mahoney , John T. Garibotto , Kerry Dennis O'Mara , Christopher Carter Gregory , John Michael Margicin , J. Christopher Flaherty
发明人： Derek Dwayne Mahoney , John T. Garibotto , Kerry Dennis O'Mara , Christopher Carter Gregory , John Michael Margicin , J. Christopher Flaherty
IPC分类号： A61M3700
CPC分类号： A61M5/1452 , A61M5/14546 , A61M2005/14506 , A61M2205/0266 , A61M2205/3592
摘要： A device for delivering fluid, such as insulin for example, to a patient. The device includes an exit port assembly, a syringe-like reservoir including a side wall extending towards an outlet connected to the exit port assembly. A threaded lead screw is received in the reservoir and a plunger has an outer periphery linearly slideable along the side wall of the reservoir and an inner periphery threadedly received on the lead screw. The plunger is non-rotatable with respect to the side wall such that rotating the lead screw causes the plunger to advance within the reservoir and force fluid through the outlet. The device also includes a dispenser having a return element for causes rotation of the lead screw, and a shape memory element. A changeable length of the shape memory element decreasing from an uncharged length to a charged length resets the return element.
摘要翻译：用于将例如胰岛素等流体输送给患者的装置。该装置包括出口端口组件，注射器状容器，其包括朝向连接到出口端口组件的出口延伸的侧壁。螺纹导螺杆被容纳在储存器中，并且柱塞具有沿着储存器的侧壁可线性滑动的外周边和螺纹地接纳在导螺杆上的内周边。柱塞相对于侧壁是不可旋转的，从而旋转导螺杆使得柱塞在储存器内前进并且迫使流体通过出口。该装置还包括具有用于引导丝杠旋转的返回元件和形状记忆元件的分配器。形状记忆元件的可变长度从不带电长度减小到带电长度，使返回元件复位。

8. 发明授权

US06387710B1 Automated sample processor 失效
标题翻译：自动样品处理器
公开(公告)号：US06387710B1
公开(公告)日：2002-05-14
申请号：US09433155
申请日：1999-11-03
申请人： Zvi Gerald Loewy , Christopher Carter Gregory , Zygmunt Marian Andrevski
发明人： Zvi Gerald Loewy , Christopher Carter Gregory , Zygmunt Marian Andrevski
IPC分类号： G01N110
CPC分类号： B01L3/502 , B01L2400/0478 , B01L2400/0622 , B01L2400/0644 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： Provided is a liquid handling device comprising: a cylindrical actuator cavity in a substrate, the actuator cavity intersected by two or more actuator channels; one or more chambers with an access channel adapted to connect to a separate one of actuator channels; and a actuator comprising (a) a cylindrical body having a cylinder axis and having therein a liquid-handling compartment with, arrayed along the cylinder axis, a first end and a second end, the liquid-handling compartment being closed at the second end, (b) a dispensing channel located at the second end and traversing the cylindrical body, the dispensing channel adapted to be separately aligned with the actuator channels, wherein the actuator is adapted to receive in a seal-tight manner a plunger that operates to confine an effective chamber defined by the plunger and the second end by moving toward the second end or to expand the effective chamber by moving toward the first end. Preferably, one or more of the chambers are formed within the substrate.
摘要翻译：提供了一种液体处理装置，包括：在基板中的圆柱形致动器空腔，致动器空腔与两个或更多个致动器通道相交; 一个或多个腔室，其具有适于连接到单独的一个致动器通道的进入通道; 以及致动器，包括（a）具有气缸轴线的圆筒体，并且具有沿着气缸轴线排列的液体处理室，第一端和第二端，液体处理室在第二端处封闭，（b）分配通道，位于第二端并横穿圆柱体，分配通道适于与致动器通道单独对准，其中致动器适于以密封方式接收柱塞，其操作以限制通过朝向第二端移动而通过柱塞和第二端限定的有效室，或者通过向第一端移动而使有效室膨胀。优选地，一个或多个室形成在衬底内。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式