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    • 8. 发明授权
    • Array for rapid detection of a microorganism
    • 用于快速检测微生物的阵列
    • US08617874B2
    • 2013-12-31
    • US12464149
    • 2009-05-12
    • Stephanie Michelle MartinJohn Gavin MacDonaldJason LyeCurt SayreKimberlee Thompson
    • Stephanie Michelle MartinJohn Gavin MacDonaldJason LyeCurt SayreKimberlee Thompson
    • C12M1/34
    • C12Q1/04
    • A method for detecting a microorganism or class of microorganisms is provided. More specifically, the method employs an array that contains a plurality of discrete regions (referred to as “addresses”) spaced apart on a solid support in a predetermined pattern. The addresses are selected so that the array provides a distinct spectral response (e.g., pattern of colors) or “fingerprint” for a particular microorganism or class of microorganisms. For example, the array may provide a certain spectral response in the presence of one microorganism or class of microoryanisms (e.g., gram-negative bacteria), but provide a completely different spectral response in the presence of another microorganism or class of microorganisms (e.g., gram-positive bacteria). Detection of the spectral response provided by the array may thus allow for differentiation between microorganisms.
    • 提供了一种用于检测微生物或微生物类别的方法。 更具体地,该方法采用包含在固体支持体上以预定图案间隔开的多个离散区域(称为“地址”)的阵列。 选择地址使得阵列为特定微生物或微生物类提供不同的光谱响应(例如,颜色图案)或“指纹”。 例如,阵列可以在一种微生物或类微生物(例如,革兰氏阴性细菌)的存在下提供特定的光谱响应,但是在另一种微生物或一类微生物的存在下提供完全不同的光谱响应(例如, 革兰氏阳性细菌)。 由阵列提供的光谱响应的检测因此可以允许微生物之间的分化。