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1. 发明授权

US06222948B1 Multiple ultrasound image registration system, method and transducer 有权
公开(公告)号：US06222948B1
公开(公告)日：2001-04-24
申请号：US09502607
申请日：2000-02-11
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： G06K900
CPC分类号： A61B8/145 , A61B8/483 , G01S7/52034 , G01S7/52065 , G01S7/52071 , G01S7/52085 , G01S15/66 , G01S15/87 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G06T7/246
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

2. 发明授权

US06201900B1 Multiple ultrasound image registration system, method and transducer 有权
标题翻译：多重超声图像配准系统，方法和传感器
公开(公告)号：US06201900B1
公开(公告)日：2001-03-13
申请号：US09340542
申请日：1999-06-28
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： G06K900
CPC分类号： A61B8/145 , A61B8/483 , G01S7/52034 , G01S7/52065 , G01S7/52071 , G01S7/52085 , G01S15/66 , G01S15/87 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G06T7/246
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.
摘要翻译：超声波成像系统包括在图像数据阵列的每一端具有图像数据阵列和跟踪阵列的超声波换能器。跟踪阵列横向于图像数据阵列。来自图像数据阵列的图像用于重建目标的三维表示。基于来自跟踪阵列的数据的帧，运动估计器自动地估计图像数据的各个帧之间的相对移动。当传感器围绕图像数据阵列的方位角旋转时，目标的特征保持在跟踪阵列的图像平面内。使用跟踪阵列的图像平面中的这些特征的运动来估计针对三维重建所需的运动。类似的技术估计图像平面内的运动以产生扩展的视场。

3. 发明授权

US6102865A Multiple ultrasound image registration system, method and transducer 有权
公开(公告)号：US6102865A
公开(公告)日：2000-08-15
申请号：US346090
申请日：1999-07-01
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： A61B8/00 , G01S7/52 , G01S15/66 , G01S15/87 , G01S15/89 , G06T7/20 , A61B8/14
CPC分类号： A61B8/145 , A61B8/483 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G01S7/52085 , G06T7/2033 , G01S15/66 , G01S15/87 , G01S7/52034 , G01S7/52065 , G01S7/52071
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

4. 发明授权

US06360027B1 Multiple ultrasound image registration system, method and transducer 失效
标题翻译：多重超声图像配准系统，方法和传感器
公开(公告)号：US06360027B1
公开(公告)日：2002-03-19
申请号：US09669818
申请日：2000-09-26
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： G06K900
CPC分类号： A61B8/145 , A61B8/483 , G01S7/52034 , G01S7/52065 , G01S7/52071 , G01S7/52085 , G01S15/66 , G01S15/87 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G06T7/246
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.
摘要翻译：超声波成像系统包括在图像数据阵列的每一端具有图像数据阵列和跟踪阵列的超声波换能器。跟踪阵列横向于图像数据阵列。来自图像数据阵列的图像用于重构目标的三维表示。基于来自跟踪阵列的数据的帧，运动估计器自动地估计图像数据的各个帧之间的相对移动。当传感器围绕图像数据阵列的方位角旋转时，目标的特征保持在跟踪阵列的图像平面内。使用跟踪阵列的图像平面中的这些特征的运动来估计针对三维重建所需的运动。类似的技术估计图像平面内的运动以产生扩展的视场。

5. 发明授权

US6132376A Multiple ultrasonic image registration system, method and transducer 有权
标题翻译：多重超声波图像配准系统，方法和传感器
公开(公告)号：US6132376A
公开(公告)日：2000-10-17
申请号：US357200
申请日：1999-07-20
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： A61B8/00 , G01S7/52 , G01S15/66 , G01S15/87 , G01S15/89 , G06T7/20
CPC分类号： A61B8/145 , A61B8/483 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G01S7/52085 , G06T7/2033 , G01S15/66 , G01S15/87 , G01S7/52034 , G01S7/52065 , G01S7/52071
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.
摘要翻译：超声波成像系统包括在图像数据阵列的每一端具有图像数据阵列和跟踪阵列的超声波换能器。跟踪阵列横向于图像数据阵列。来自图像数据阵列的图像用于重构目标的三维表示。基于来自跟踪阵列的数据的帧，运动估计器自动地估计图像数据的各个帧之间的相对移动。当传感器围绕图像数据阵列的方位角旋转时，目标的特征保持在跟踪阵列的图像平面内。使用跟踪阵列的图像平面中的这些特征的运动来估计针对三维重建所需的运动。类似的技术估计图像平面内的运动以产生扩展的视场。

6. 发明授权

US6014473A Multiple ultrasound image registration system, method and transducer 失效
公开(公告)号：US6014473A
公开(公告)日：2000-01-11
申请号：US916585
申请日：1997-08-22
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： A61B8/00 , G01S7/52 , G01S15/66 , G01S15/87 , G01S15/89 , G06T7/20 , G06K9/32
CPC分类号： A61B8/145 , A61B8/483 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G01S7/52085 , G06T7/2033 , G01S15/66 , G01S15/87 , G01S7/52034 , G01S7/52065 , G01S7/52071
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

7. 发明授权

US06489706B2 Medical diagnostic ultrasound transducer and method of manufacture 失效
标题翻译：医用诊断超声换能器及其制造方法
公开(公告)号：US06489706B2
公开(公告)日：2002-12-03
申请号：US09191653
申请日：1998-11-13
申请人： John W. Sliwa, Jr. , Rick L. Edmiston , Matthew T. Spigelmyer , Vaughn R. Marian, Jr. , John P. Mohr, III , John A. Hossack
发明人： John W. Sliwa, Jr. , Rick L. Edmiston , Matthew T. Spigelmyer , Vaughn R. Marian, Jr. , John P. Mohr, III , John A. Hossack
IPC分类号： H01L4104
CPC分类号： B06B1/0622 , B06B1/0607 , B06B2201/76
摘要： A plurality of piezomaterial bodies, such as panels or slices, are merged together to form a larger piezomaterial body. For example, a 0.75×22 cm polycrystalline piezomaterial body is formed, where the distances are along lateral or footprint dimensions. The thickness of the piezomaterial body is substantially less than either of the distances along first and second lateral dimensions that define the footprint. Preferably, each piezomaterial body has a panel shape, and a plurality of panels are merged to form a large multi-panel.
摘要翻译：多个压电材料体（例如面板或切片）被合并在一起以形成较大的压电材料体。例如，形成0.75×22cm的多晶压电材料体，其中距离沿着横向或覆盖尺寸。压电材料体的厚度基本上小于沿着限定覆盖区的第一和第二横向尺寸的任何一个距离。优选地，每个压电材料体具有面板形状，并且多个面板被合并以形成大的多面板。

8. 发明授权

US5749364A Method and apparatus for mapping pressure and tissue properties 失效
标题翻译：用于绘制压力和组织性质的方法和装置
公开(公告)号：US5749364A
公开(公告)日：1998-05-12
申请号：US667765
申请日：1996-06-21
申请人： John W. Sliwa, Jr. , Michelle L. Jung , Paul E. Chandler , Amin M. Hanafy , David J. Napolitano
发明人： John W. Sliwa, Jr. , Michelle L. Jung , Paul E. Chandler , Amin M. Hanafy , David J. Napolitano
IPC分类号： A61B8/00 , A61B8/08
CPC分类号： A61B8/481 , A61B8/04 , A61B8/08
摘要： The invention disclosed relates to a novel method of mapping and presenting fluid pressure information within a living body utilizing changes in acoustic behavior of microbubbles situated in a bodily fluid such as blood. Differences in the returned acoustic spectra from the microbubbles are related by an algorithm to fluid pressure which is colorized and presented in a manner similar to Doppler imaging. In a further aspect of the invention, the work output of an organ such as the heart may computed from the blood pressure information in association with flow information obtained through Doppler related imaging, which then, is presented in a colorized fashion. In a still further aspect, an improved method of assessing the health of tissue is disclosed utilizing changes in the acoustic spectra of microbubbles infused in the tissue in response to palpitation.
摘要翻译：本发明涉及利用位于诸如血液之类的体液中的微泡的声学行为的变化来映射和呈现活体内的流体压力信息的新方法。来自微泡的返回声谱中的差异通过与以多普勒成像相似的方式着色和呈现的流体压力的算法相关。在本发明的另一方面，可以根据通过多普勒相关成像获得的流量信息与血压信息计算诸如心脏的器官的工作输出，然后通过多普勒相关成像获得，然后以彩色方式呈现。在另一方面，利用在响应心悸输注在组织中的微泡的声谱的变化来公开评估组织健康的改进方法。

9. 发明授权

US09089287B2 Image-guided ablation system and method for monitoring an ablation procedure 有权
标题翻译：图像引导消融系统和消融程序监测方法
公开(公告)号：US09089287B2
公开(公告)日：2015-07-28
申请号：US12346132
申请日：2008-12-30
申请人： John W. Sliwa, Jr. , Stephen A. Morse
发明人： John W. Sliwa, Jr. , Stephen A. Morse
IPC分类号： A61B8/00 , A61B18/14 , A61B8/12 , A61B8/08 , A61B18/02 , A61B18/18 , A61B18/20 , A61B19/00 , A61N7/02
CPC分类号： A61B8/12 , A61B8/00 , A61B8/0841 , A61B8/4245 , A61B8/445 , A61B8/463 , A61B18/02 , A61B18/14 , A61B18/18 , A61B18/20 , A61B2090/3782 , A61B2090/3784 , A61N7/02 , A61N7/022
摘要： An ablation system comprises a tool including an shaft having proximal and distal end portions, a handle at the proximal end portion, and a lumen extending between the proximal and distal end portions. The system further includes an ablation subsystem comprised of an ablation element at the distal end portion of the shaft, and an ablation source connected to the ablation element. The system further includes an imaging subsystem comprising an ultrasound imaging transducer disposed proximate the ablation element. The transducer is pivotally attached to the shaft or the ablation element to allow the transducer to articulate between stowed and deployed positions. The imaging subsystem further comprises a processor connected to the transducer configured to receive image data acquired by the transducer, and to generate an image corresponding thereto. The imaging subsystem still further includes a display connected to the processor configured to display the generated image.
摘要翻译：消融系统包括工具，其包括具有近端部分和远端部分的轴，在近端部分处的手柄以及在近端部分和远端部分之间延伸的内腔。该系统还包括消融子系统，其包括在轴的远端部分处的消融元件和连接到消融元件的消融源。该系统还包括成像子系统，其包括邻近消融元件设置的超声成像换能器。换能器枢转地附接到轴或消融元件，以允许换能器在收起位置和展开位置之间铰接。成像子系统还包括连接到换能器的处理器，其被配置为接收由换能器获取的图像数据，并且生成与其对应的图像。成像子系统还包括连接到处理器的显示器，其被配置为显示生成的图像。

10. 发明授权

US06359367B1 Micromachined ultrasonic spiral arrays for medical diagnostic imaging 失效
标题翻译：用于医疗诊断成像的微加工超声波螺旋阵列
公开(公告)号：US06359367B1
公开(公告)日：2002-03-19
申请号：US09455881
申请日：1999-12-06
申请人： Thilaka S. Sumanaweera , Sevig Ayter , John W. Sliwa, Jr.
发明人： Thilaka S. Sumanaweera , Sevig Ayter , John W. Sliwa, Jr.
IPC分类号： H02N100
CPC分类号： B06B1/0292
摘要： Spiral, sparse spiral, substantially spiral or substantially sparse spiral transducer arrays comprising capacitive micromachined ultrasonic transducer elements disposed on a silicon substrate, and ultrasound imaging systems employing same. The transducer elements are respectively coupled to a plurality of amplifiers. Imager electronics are coupled to each of the amplifiers and drives the transducer elements and/or generates an output of the spiral transducer array. The amplifiers may be located in the silicon substrate containing the transducer elements, or on a separate substrate that is interconnected to the substrate containing the transducer elements using bumps, for example. Electrical interconnection to the transducer elements may readily be achieved without interfering with the acoustic output of the transducer elements.
摘要翻译：包括设置在硅衬底上的电容微加工超声换能器元件的螺旋，稀疏螺旋，基本螺旋或基本上稀疏的螺旋形换能器阵列，以及采用其的超声成像系统。换能器元件分别耦合到多个放大器。成像仪电子器件耦合到每个放大器并驱动换能器元件和/或产生螺旋换能器阵列的输出。放大器可以位于包含换能器元件的硅衬底中，或者位于使用例如使用凸块互连到包含换能器元件的衬底的单独衬底上。可以容易地实现与换能器元件的电互连，而不会干扰换能器元件的声输出。

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