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1. 发明授权

US06864989B2 Method for illuminating an object with light from a laser light source 有权
标题翻译：用于用来自激光光源的光照射物体的方法
公开(公告)号：US06864989B2
公开(公告)日：2005-03-08
申请号：US09939726
申请日：2001-08-28
申请人： Rafael Storz , Johann Engelhardt , Holger Birk
发明人： Rafael Storz , Johann Engelhardt , Holger Birk
IPC分类号： G02B26/06 , G02B21/00 , G02B21/06 , G02F1/01 , H01S3/00 , G01B11/24
CPC分类号： G02B21/0024 , G02B21/0056
摘要： A method for illuminating an object with light (2) from a laser light source (3), preferably in a confocal scanning microscope (1). With the method according to the invention, it is possible to reduce the coherence length of the laser light, so that disruptive interference phenomena can be substantially eliminated. Should interference phenomena nevertheless be formed, these are to be influenced in such a way that they have no effect on the detection. The method according to the invention is characterized in that the phase angle of the light field is varied by a modulator in such a way that interference phenomena do not occur in the optical beam path, or occur only to an undetectable extent, within a predeterminable time interval.
摘要翻译：优选在共焦扫描显微镜（1）中从激光光源（3）用光（2）照射物体的方法。利用根据本发明的方法，可以减少激光的相干长度，从而可以基本上消除破坏性干扰现象。应该如何形成干扰现象，这些影响将不会对检测产生影响。根据本发明的方法的特征在于，光场的相位角由调制器改变，使得在预定时间内在光束路径中不发生干涉现象或仅发生不可检测的程度间隔。

2. 发明授权

US06796699B2 Laser illuminator and method 有权
标题翻译：激光照明器及方法
公开(公告)号：US06796699B2
公开(公告)日：2004-09-28
申请号：US09881212
申请日：2001-06-15
申请人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
发明人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
IPC分类号： F21V1400
CPC分类号： G02B6/02376 , B82Y20/00 , G02B6/02366 , G02B6/02371 , G02B6/1225 , G02B6/2552 , G02B21/002 , G02B21/0032 , G02B21/0056 , G02B21/0064 , G02B21/0076 , G02B21/008 , G02B21/06 , G02B27/0994 , H01S3/005 , H01S3/1625 , H01S3/1636
摘要： A method for illuminating an object (79). The method is characterized by the steps of injecting (1) the light beam (13) from a laser (9) into a microstructured optical element (19), which spectrally broadens the light of the light beam (13), shaping (3) the spectrally broadened light (31) to form an illumination light beam (29), and directing (5) the illumination light beam (29) onto the object (79). An instrument (7) for illuminating an object (79). The instrument comprises a laser (9) that emits a light beam (13), which is directed onto a microstructured optical element (19) that spectrally broadens the light from the laser. A optical means (33) which shapes the spectrally broadened light (31) to form an illumination light beam (29) is arranged downstream of the microstructured optical element (19).
摘要翻译：一种照明物体（79）的方法。该方法的特征在于以下步骤：将来自激光器（9）的光束（13）注入到微结构化光学元件（19）中，该光学元件光谱（13）的光线变宽，成形（3）光谱变宽的光（31）形成照明光束（29），并将照明光束（29）引导到物体（79）上。一种用于照明物体（79）的仪器（7）。仪器包括发射光束（13）的激光器（9），该激光器被引导到光学拓宽来自激光器的光的微结构化光学元件（19）上。形成光谱变宽的光（31）以形成照明光束（29）的光学装置（33）布置在微结构化光学元件（19）的下游。

3. 发明授权

US06567164B2 Entangled-photon microscope and confocal microscope 有权
公开(公告)号：US06567164B2
公开(公告)日：2003-05-20
申请号：US09880825
申请日：2001-06-15
申请人： Holger Birk , Rafael Storz , Johann Engelhardt
发明人： Holger Birk , Rafael Storz , Johann Engelhardt
IPC分类号： G01N2163
CPC分类号： G02B6/02328 , B82Y20/00 , G02B6/02347 , G02B6/02361 , G02B6/02366 , G02B6/02371 , G02B6/1225 , G02B6/2552 , G02B21/002 , G02B21/0032 , G02B21/0056 , G02B21/0064 , G02B21/0076 , G02B21/008 , G02B21/06 , H01S3/005 , H01S3/1625 , H01S3/1636
摘要： The invention discloses an entangled-photon microscope (1) having a light source (3) and an objective (31). The entangled-photon microscope (1) has a microstructured optical element (11), in which entangled photons can be produced, between the light source (3) and the objective (31), the entangled photons propagating in a beam (15) inside and outside the microstructured optical element.

4. 发明授权

US07110645B2 Method and instrument for microscopy 有权
标题翻译：显微镜法和仪器
公开(公告)号：US07110645B2
公开(公告)日：2006-09-19
申请号：US10964034
申请日：2004-10-13
申请人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
发明人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
IPC分类号： G02B6/06 , G02B21/00
CPC分类号： G02B6/02376 , B82Y20/00 , G02B6/02366 , G02B6/02371 , G02B6/1225 , G02B6/2552 , G02B21/002 , G02B21/0024 , G02B21/0032 , G02B21/0056 , G02B21/0064 , G02B21/0068 , G02B21/0076 , G02B21/008 , G02B21/06 , H01S3/005 , H01S3/1625 , H01S3/1636 , Y10S385/901
摘要： A microscope includes a light source that emits an illuminating light beam for illumination of a specimen, a beam splitter separating measuring light out of the illuminating light beam, and an apparatus for determining the light power level of the illuminating light beam. The apparatus for determining the light power level of the illuminating light beam receives the measuring light and includes an apparatus for simultaneous color-selective detection of the measuring light.
摘要翻译：显微镜包括发射用于照射样本的照明光束的光源，分离出照射光束的测量光的分束器和用于确定照明光束的光功率水平的装置。用于确定照明光束的光功率电平的装置接收测量光，并且包括用于同时对测量光进行颜色选择性检测的装置。

5. 发明授权

US06909540B2 Microscope objective, microscope, and method for imaging a specimen 有权
标题翻译：显微镜目标，显微镜和成像成像方法
公开(公告)号：US06909540B2
公开(公告)日：2005-06-21
申请号：US10308608
申请日：2002-12-02
申请人： Johann Engelhardt , Rafael Storz
发明人： Johann Engelhardt , Rafael Storz
IPC分类号： G02B7/04 , G02B21/00 , G02B21/02 , G02B21/24
CPC分类号： G02B21/02 , G02B21/241
摘要： A microscope objective that comprises an objective housing and contains several lens elements, at least one lens element being arranged displaceably in motor-driven fashion within the objective housing, is disclosed. A microscope and a method for imaging a specimen are additionally disclosed.
摘要翻译：公开了一种显微镜物镜，其包括物镜壳体并且包含若干透镜元件，至少一个透镜元件以电机驱动的方式在物镜壳体内可移位地布置。另外公开了用于成像试样的显微镜和方法。

6. 发明授权

US07002717B1 Apparatus for beam deflection 有权
标题翻译：光束偏转装置
公开(公告)号：US07002717B1
公开(公告)日：2006-02-21
申请号：US09681014
申请日：2000-11-20
申请人： Rafael Storz , Johann Engelhardt , Holger Birk , Joachim Bradl
发明人： Rafael Storz , Johann Engelhardt , Holger Birk , Joachim Bradl
IPC分类号： G02B26/08
CPC分类号： G02B21/0048
摘要： The invention concerns an apparatus for beam deflection, in particular for scanning microscopy, a light beam being deflectable by a mirror arrangement that is alternatingly rotatable by a rotary drive. The apparatus for beam deflection makes possible maximum variability in terms of frequency range and maximally achievable oscillation frequency, and is thus usable in flexible and versatile fashion. It moreover allows almost any desired angular offset from the zero point position to be established, and is characterized in that the rotary drive comprises two mutually independent drive units which rotate the mirror arrangement, together or mutually independently, about a rotation axis.
摘要翻译：本发明涉及一种用于光束偏转的装置，特别是用于扫描显微镜的光束，可通过由旋转驱动器交替旋转的反射镜装置偏转。用于光束偏转的装置在频率范围和最大可实现的振荡频率方面可能是最大的可变性，因此可以灵活和多用途的方式使用。此外，它允许几乎任何期望的从零点位置的角度偏移被建立，并且其特征在于，旋转驱动器包括两个相互独立的驱动单元，其将反射镜装置围绕旋转轴线一起或相互独立地旋转。

7. 发明申请

US20050111816A1 Method and instrument for microscopy 有权
标题翻译：显微镜法和仪器
公开(公告)号：US20050111816A1
公开(公告)日：2005-05-26
申请号：US10964034
申请日：2004-10-13
申请人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
发明人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
IPC分类号： G02B6/02 , G02B6/122 , G02B6/255 , G02B21/00 , G02B21/06 , G02B27/00 , H01S3/00 , H01S3/16 , G02B6/00
CPC分类号： G02B6/02376 , B82Y20/00 , G02B6/02366 , G02B6/02371 , G02B6/1225 , G02B6/2552 , G02B21/002 , G02B21/0024 , G02B21/0032 , G02B21/0056 , G02B21/0064 , G02B21/0068 , G02B21/0076 , G02B21/008 , G02B21/06 , H01S3/005 , H01S3/1625 , H01S3/1636 , Y10S385/901
摘要： A microscope includes a light source that emits an illuminating light beam for illumination of a specimen, a beam splitter separating measuring light out of the illuminating light beam, and an apparatus for determining the light power level of the illuminating light beam. The apparatus for determining the light power level of the illuminating light beam receives the measuring light and includes an apparatus for simultaneous color-selective detection of the measuring light.
摘要翻译：显微镜包括发射用于照射样本的照明光束的光源，分离出照射光束的测量光的分束器和用于确定照明光束的光功率水平的装置。用于确定照明光束的光功率电平的装置接收测量光，并且包括用于同时对测量光进行颜色选择性检测的装置。

8. 发明授权

US06567212B1 Vibration damping device for microscopes and microscope with a vibration damping device 有权
标题翻译：具有减振装置的显微镜和显微镜振动阻尼装置
公开(公告)号：US06567212B1
公开(公告)日：2003-05-20
申请号：US09639592
申请日：2000-08-16
申请人： Johann Engelhardt , Rafael Storz
发明人： Johann Engelhardt , Rafael Storz
IPC分类号： G02B2100
CPC分类号： G02B21/24
摘要： A Vibration damping device for a microscope comprises a housing. In the housing a foam rubber defining a cavity is formed which encloses a weight. The foam rubber has a plurality of interconnected pores. The housing is of the vibration damping device has in one embodiment a rectangular shape.
摘要翻译：用于显微镜的振动阻尼装置包括壳体。在壳体中形成限定空腔的泡沫橡胶，其包围重物。泡沫橡胶具有多个互连孔。在一个实施例中，壳体是减振装置的矩形形状。

9. 发明授权

US06898367B2 Method and instrument for microscopy 有权
标题翻译：显微镜法和仪器
公开(公告)号：US06898367B2
公开(公告)日：2005-05-24
申请号：US09881049
申请日：2001-06-15
申请人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
发明人： Holger Birk , Rafael Storz , Johann Engelhardt , Kyra Moellmann
IPC分类号： G02B6/02 , G02B6/122 , G02B6/255 , G02B21/00 , G02B21/06 , G02B27/00 , H01S3/00 , H01S3/16 , G02B6/00 , H01S3/30
CPC分类号： G02B6/02376 , B82Y20/00 , G02B6/02366 , G02B6/02371 , G02B6/1225 , G02B6/2552 , G02B21/002 , G02B21/0024 , G02B21/0032 , G02B21/0056 , G02B21/0064 , G02B21/0068 , G02B21/0076 , G02B21/008 , G02B21/06 , H01S3/005 , H01S3/1625 , H01S3/1636 , Y10S385/901
摘要： A method for illuminating is disclosed, which is characterized by the steps of injecting (1) the light beam (13) from a laser (9) into a optical element (19), which spectrally broadens the light of the light beam (13) and shaping (3) the spectrally broadened light (31) to form an illumination light beam (29). An instrument (7) for illuminating is furthermore disclosed, which comprises a laser (9) that emits a light beam (13), which is directed onto a optical element (19) that spectrally broadens the light from the laser. A optical means (33) which shapes the spectrally broadened light (31) to form an illumination light beam (29) is arranged downstream of the microstructured optical element (19).
摘要翻译：公开了一种用于照明的方法，其特征在于以下步骤：将来自激光器（9）的光束（13）注入到光学元件（19）中，该光学元件使光束（13）的光谱扩展，以及（3）使光谱变宽的光（31）成形以形成照明光束（29）。此外还公开了一种用于照明的仪器（7），其包括发射光束（13）的激光（9），所述激光（9）被引导到光学元件（19）上，所述光学元件（19）对来自激光器的光进行光谱加宽。形成光谱变宽的光（31）以形成照明光束（29）的光学装置（33）布置在微结构化光学元件（19）的下游。

10. 发明授权

US06737635B2 Apparatus for combining light and confocal scanning microscope 有权
标题翻译：用于组合光和共焦扫描显微镜的装置
公开(公告)号：US06737635B2
公开(公告)日：2004-05-18
申请号：US09825273
申请日：2001-04-03
申请人： Johann Engelhardt , Juergen Hoffmann , Rafael Storz , Heinrich Ulrich , Joerg Bewersdorf , Holger Birk
发明人： Johann Engelhardt , Juergen Hoffmann , Rafael Storz , Heinrich Ulrich , Joerg Bewersdorf , Holger Birk
IPC分类号： H01J4014
CPC分类号： G02B21/0068 , G02B21/0032 , G02B21/0056 , G02B27/283
摘要： The present invention concerns an apparatus for combining light from at least two laser light sources, preferably in the context of confocal scanning microscopy, and in order to make laser light sources of low output power usable as light sources, in particular for confocal scanning microscopy, is characterized in that the light from the laser light sources has at least approximately the same wavelength; and that at least one beam combining unit that combines the light beams in at least largely lossless fashion is provided.
摘要翻译：本发明涉及一种用于组合来自至少两个激光源的光的装置，优选在共聚焦扫描显微镜的上下文中，并且为了使得可用作光源的低输出功率的激光光源，特别是用于共聚焦扫描显微镜，其特征在于，来自激光光源的光具有至少大致相同的波长; 并且提供以至少大部分无损方式组合光束的至少一个光束组合单元。

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