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1. 发明授权

US08408899B1 Dental delivery systems, related components and methods 有权
标题翻译：牙科输送系统，相关组件和方法
公开(公告)号：US08408899B1
公开(公告)日：2013-04-02
申请号：US11424525
申请日：2006-06-15
申请人： Joel P. Smith , Jonathan E. Myers , Paul H. Johnson , J. Rick Halbirt , Patrick W. Berry , Stephen N. Weiler , Harold Halvorson, Jr.
发明人： Joel P. Smith , Jonathan E. Myers , Paul H. Johnson , J. Rick Halbirt , Patrick W. Berry , Stephen N. Weiler , Harold Halvorson, Jr.
IPC分类号： A61C13/38 , B01L9/02
CPC分类号： A61G12/005 , A61C19/00 , A61G15/02 , A61G15/16
摘要： Described herein are various embodiments of a dental delivery system. For example, in one exemplary embodiment, a rear dental delivery system through which at least one of water, air and vacuum are delivered for use by a care giver in treating a patient occupying a nearby dental chair can include at least one movable arm that is pivotably mounted to a pivot connection and an upright mounted to the at least one movable arm. The pivot connection can be mounted at approximately a floor level and the at least one movable arm can be configured to pivot slightly above the floor level so as to reduce obstruction in a space separating the dental chair from the dental delivery system.
摘要翻译：这里描述的是牙科输送系统的各种实施例。例如，在一个示例性实施例中，后部牙齿输送系统通过其中的水，空气和真空中的至少一个被输送以供照护者使用以治疗占据附近的牙科椅子的患者，所述后牙齿递送系统可以包括至少一个可移动臂可枢转地安装到枢转连接件和安装到所述至少一个可动臂上的直立件。枢转连接可以安装在大约地板水平处，并且所述至少一个可动臂可以构造成稍微高于地板水平面，以便减少将牙科椅与牙科输送系统分开的空间中的阻塞。

2. 发明授权

US09464300B2 Multiblock copolymers 有权
标题翻译：多嵌段共聚物
公开(公告)号：US09464300B2
公开(公告)日：2016-10-11
申请号：US13127959
申请日：2009-11-06
申请人： Mary G. Prieve , Paul H. Johnson , Patrick S. Stayton , Allan S. Hoffman , Robert W. Overell , Anna S. Gall , Amber E. E. Paschal , Charbel Diab , Priyadarsi De , Michael S. DeClue , Sean D. Monahan
发明人： Mary G. Prieve , Paul H. Johnson , Patrick S. Stayton , Allan S. Hoffman , Robert W. Overell , Anna S. Gall , Amber E. E. Paschal , Charbel Diab , Priyadarsi De , Michael S. DeClue , Sean D. Monahan
IPC分类号： C12N15/87 , C08F293/00 , A61K31/713 , A61K48/00 , C08F220/28
CPC分类号： A61K31/713 , A61K47/545 , A61K47/58 , A61K47/6907 , A61K48/00 , C08F293/005 , C08F2220/286 , C08F2438/03 , C12N15/113 , C12N15/87 , C12N2310/14 , Y02A50/411 , C08F220/34
摘要： Provided herein are multiblock copolymers, as well as micelles and therapeutic compositions thereof.
摘要翻译：本文提供多嵌段共聚物，以及胶束和其治疗组合物。

3. 发明授权

US09415113B2 Targeting monomers and polymers having targeting blocks 有权
标题翻译：靶向具有靶向块的单体和聚合物
公开(公告)号：US09415113B2
公开(公告)日：2016-08-16
申请号：US13510279
申请日：2010-11-17
申请人： Sean D. Monahan , Paul H. Johnson , Michael S. DeClue , Priyadarsi De , Anna S. Gall , Patrick S. Stayton , Allan S. Hoffman , Charbel Diab
发明人： Sean D. Monahan , Paul H. Johnson , Michael S. DeClue , Priyadarsi De , Anna S. Gall , Patrick S. Stayton , Allan S. Hoffman , Charbel Diab
IPC分类号： A61K31/787 , C07D221/02 , A61K47/06 , A61K47/48
CPC分类号： A61K47/48176 , A61K47/551 , A61K47/557 , A61K47/58 , A61K47/62
摘要： Provided herein are monomers incorporating folate or other targeting agent, polymers prepared therefrom, polymers prepared therefrom having a therapeutic agent covalently coupled thereto, as well as micelles and therapeutic compositions thereof.
摘要翻译：本文提供了含有叶酸盐或其它靶向剂的单体，由其制备的聚合物，由其制备的聚合物，其具有与其共价偶联的治疗剂，以及胶束和其治疗组合物。

4. 发明申请

US20110143435A1 POLYMERIC CARRIER 有权
标题翻译：聚合载体
公开(公告)号：US20110143435A1
公开(公告)日：2011-06-16
申请号：US12992536
申请日：2009-05-13
申请人： Patrick S. Stayton , Allan S. Hoffman , Anthony J. Convertine , Craig L. Duvall , Danielle Benoit , Robert W. Overell , Paul H. Johnson , Anna S. Gall , Mary G. Prieve , Amber E.E. Paschal , Charbel Diab , Priyadarsi De
发明人： Patrick S. Stayton , Allan S. Hoffman , Anthony J. Convertine , Craig L. Duvall , Danielle Benoit , Robert W. Overell , Paul H. Johnson , Anna S. Gall , Mary G. Prieve , Amber E.E. Paschal , Charbel Diab , Priyadarsi De
IPC分类号： C12N5/071 , C08F8/40
CPC分类号： A61K47/488 , A61K9/1075 , A61K47/549 , A61K47/58 , A61K47/60 , A61K47/6907 , C08F293/005 , C12N15/113 , C12N15/87 , C12N2310/11 , C12N2310/14
摘要： Provided herein are polymeric carriers suitable for the delivery of polynucleotides (e.g. oligonucleotides) and/or other therapeutic agents into a living cell.
摘要翻译：本文提供适合于将多核苷酸（例如寡核苷酸）和/或其它治疗剂递送至活细胞的聚合物载体。

5. 发明授权

US5697115A Cleaning apparatus with triangular shaped mount for attachment and quick disconnect 失效
标题翻译：具有三角形安装座的清洁装置用于附接和快速断开
公开(公告)号：US5697115A
公开(公告)日：1997-12-16
申请号：US639661
申请日：1996-04-29
申请人： James F. Sciarra , Patrick N. Gutelius , Paul H. Johnson
发明人： James F. Sciarra , Patrick N. Gutelius , Paul H. Johnson
IPC分类号： A47L11/14 , A46B13/00 , F16D1/112 , A47L11/16
CPC分类号： F16D1/112 , A46B13/008 , Y10T403/7005
摘要： A cleaning apparatus having a housing, a motor, a transmission, an attachment stud, and a cleaning attachment removably connected to the stud. The stud has a leading section with a general triangular block shape and three generally triangular shaped cantilevered tips. The stud is received through a generally triangular shaped aperture in the cleaning attachment. The apparatus can reverse the normal rotation direction of the stud to allow the cleaning attachment to quickly disconnect from the stud without a user having to hold the cleaning attachment.
摘要翻译：具有外壳，电动机，变速器，附接柱和清洁附件的清洁装置可移除地连接到螺柱。螺柱具有一般的三角形块形状的前导部分和三个大致三角形的悬臂尖端。螺柱通过清洁附件中的大致三角形的孔容纳。该装置可以反转螺柱的正常旋转方向，以允许清洁附件快速地从螺柱脱离，而不需要用户固定清洁附件。

6. 发明授权

US5201609A Cellular landfill process and apparatus 失效
标题翻译：蜂窝填埋过程和设备
公开(公告)号：US5201609A
公开(公告)日：1993-04-13
申请号：US734796
申请日：1991-07-23
申请人： Paul H. Johnson
发明人： Paul H. Johnson
IPC分类号： B09B1/00 , E02D31/00
CPC分类号： E02D31/002 , B09B1/00
摘要： The present invention is directed to a process and apparatus wherein municipal refuse, and many other types of solid waste, are disposed of in a landfill repository that maintains them in a dry state indefinitely. This eliminates most environmental and many cost problems. The principal design feature of this landfill is its cellular internal structure, which has rows of contiguous, rectangular water- and gas-tight cells that are built on top of one another to form a high, multi-layered structure. These cells are simultaneously constructed and filled with solid waste in a series of short, incremental wall berm construction and filling steps on a one-cell-at-a-time basis in the top layer of the landfill. The sides of the structure and the tops of the cells in the top layer are continuously protected from rain infiltration by impervious covers, and uncontaminated rain waters, leachates, leakage, and gases are separately withdrawn from the system on a cell-by-cell basis by an internal plumbing and monitoring system. Biodegradation is used in cells in the top layer to produce methane gas.
摘要翻译：本发明涉及一种方法和装置，其中将城市垃圾和许多其它类型的固体废物处理在垃圾填埋库中，将其无限期地保持在干燥状态。这消除了大多数环境和许多成本问题。该垃圾填埋场的主要设计特征是其蜂窝内部结构，其具有连续的矩形水和气密电池排，其彼此顶部构成以形成高的多层结构。这些电池同时构造并填充固体废物，这些固体废物在垃圾填埋场的顶层中以一个单元为单位的一系列短的，增量的墙壁施工和填充步骤。顶层的结构侧面和顶部的细胞被不透水的盖子连续地防止雨渗入，未受污染的雨水，渗滤液，渗漏物和气体在逐个基础上分别从系统中抽出通过内部管道和监控系统。生物降解用于顶层的细胞中以产生甲烷气。

7. 发明授权

US4579567A Agglomerating carbon black using cyclone at entrance to bag filter 失效
标题翻译：使用气旋在袋式过滤器入口处聚集炭黑
公开(公告)号：US4579567A
公开(公告)日：1986-04-01
申请号：US651736
申请日：1984-09-18
申请人： Paul H. Johnson
发明人： Paul H. Johnson
IPC分类号： B01D46/02 , B01D50/00 , B01D29/14
CPC分类号： B01D46/02 , B01D50/002 , Y10S55/25
摘要： A cyclonic agglomerator is used in the inlet line for quenched carbon black smoke into a bag house to increase the efficiency of carbon black processing.
摘要翻译：在入口管线中使用旋风式聚集器将淬火的炭黑烟雾引入袋屋，以提高炭黑加工的效率。

8. 发明申请

US20110305660A1 OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION 有权
标题翻译：欧米茄官能团聚合物，结构官能团嵌段共聚物，聚合物生物聚合物和放射链扩展聚合
公开(公告)号：US20110305660A1
公开(公告)日：2011-12-15
申请号：US13133355
申请日：2009-12-08
申请人： Patrick S. Stayton , Allan S. Hoffman , Anthony J. Convertine , Scott M. Henry , Robert W. Overell , Paul H. Johnson
发明人： Patrick S. Stayton , Allan S. Hoffman , Anthony J. Convertine , Scott M. Henry , Robert W. Overell , Paul H. Johnson
IPC分类号： A61K31/795 , A61P9/00 , C08F120/56 , A61K31/787 , C08F120/34 , C08F293/00
CPC分类号： C08F293/005 , A61K47/58 , A61K49/0054 , C08F2/38 , C08F220/54 , C08F2438/03 , C12N15/111 , C12N2320/32
摘要： Polymeric compounds having spatially controlled bioconjugation sites are described. Functionalization is achieved by selective co-terminal chain extension of polymer chains by radical polymerization, such as reversible addition-fragmentation chain transfer (RAFT) polymerization.
摘要翻译：描述了具有空间控制的生物共轭位点的聚合物。官能化通过自由基聚合如可逆加成 - 断裂链转移（RAFT）聚合的聚合物链的选择性共末端链延伸来实现。

9. 发明授权

US5652398A Fixed-volume injector with backflush capability 失效
标题翻译：具有反吹能力的固定量注射器
公开(公告)号：US5652398A
公开(公告)日：1997-07-29
申请号：US609223
申请日：1996-03-01
申请人： Paul H. Johnson
发明人： Paul H. Johnson
IPC分类号： G01N30/02 , G01N30/08 , G01N30/16 , G01N30/20 , G01N30/38 , G01N30/40 , G01N30/60 , G01N30/00
CPC分类号： G01N30/60 , G01N30/16 , G01N30/20 , G01N30/40 , G01N2030/025 , G01N2030/085 , G01N2030/205 , G01N2030/385 , G01N2030/402 , G01N30/6095
摘要： A fixed-volume injector assembly having backflush capability is useful for injecting a sample into a gas chromatograph. The injector assembly has a sampling mode of operation, an injection mode of operation and a backflush mode of operation. In the sampling mode, sample is drawn into sampling chamber (11). In the injection mode, sample is injected into an injection channel which conducts the sample to a destination stream. In the backflush mode, carrier fluid flows through the injector assembly in the opposite direction. The injector assembly is designed to connect to precolumn (28) and analytical column (20) so that, in the backflush mode, precolumn (28) is backflushed. Advantages of the injector assembly include the ability to pressurize the sample before injection and to use a single carrier fluid source. In addition, the flow channels of the injector assembly are readily miniaturized.
摘要翻译：具有反吹能力的固定量的注射器组件可用于将样品注入气相色谱仪中。喷射器组件具有采样操作模式，喷射操作模式和反吹操作模式。在取样模式下，将样品吸入取样室（11）。在注射模式中，将样品注入到将样品传导到目标流的注入通道中。在反吹模式下，载体流体沿相反方向流过喷射器组件。喷射器组件被设计成连接到预柱（28）和分析柱（20），使得在反冲模式中，预柱（28）被反冲洗。注射器组件的优点包括在注射之前对样品加压并使用单载体流体源的能力。此外，喷射器组件的流动通道容易地小型化。

10. 发明授权

US5187075A Cloning and expression of a variant gene of platelet factor 4 and compositions thereof to modulate immune responses 失效
标题翻译：平板因子4的变异基因的克隆和表达及其组合物来调节免疫应答
公开(公告)号：US5187075A
公开(公告)日：1993-02-16
申请号：US302425
申请日：1989-01-26
申请人： Christopher J. Green , Paul H. Johnson
发明人： Christopher J. Green , Paul H. Johnson
IPC分类号： C12N15/09 , A61K38/00 , A61P37/04 , C07K1/22 , C07K14/00 , C07K14/52 , C12N1/21 , C12N15/12 , C12N15/19 , C12P21/02 , C12R1/19
CPC分类号： C07K14/522 , A61K38/00 , Y10S530/829
摘要： The present invention provides for the purification from native sources or the cloning and expression of a variant form of platelet factor 4 and also provides recombinant DNA vectors and methods for the expression and recovery of the platelet factor 4 variant. Also provided are compositions and methods for modulating immune responses in mammals comprising immunomodulating effective amounts of platelet factor 4 variant.
摘要翻译：本发明提供从天然来源的纯化或血小板因子4的变体形式的克隆和表达，并提供用于表达和回收血小板因子4变体的重组DNA载体和方法。还提供了用于调节哺乳动物中的免疫应答的组合物和方法，包括免疫调节有效量的血小板因子4变体。

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