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1. 发明授权

US09271647B2 Methods for objectively determining the visual axis of the eye and measuring its refraction 有权
$Methods for objectively determining the visual axis of the eye and measuring its refraction$
标题翻译：客观地确定眼睛视轴并测量其折射的方法
公开(公告)号：US09271647B2
公开(公告)日：2016-03-01
申请号：US14102257
申请日：2013-12-10
申请人： Joe S. Wakil , Paul van Saarloos , Vasyl Molebny , Sergiy Molebny
发明人： Joe S. Wakil , Paul van Saarloos , Vasyl Molebny , Sergiy Molebny
IPC分类号： A61B3/14 , A61B3/00 , A61B3/107 , A61B3/10 , A61B3/103
CPC分类号： A61B3/107 , A61B3/0025 , A61B3/028 , A61B3/1015 , A61B3/103
摘要： Provided are methods for determining an axis of best vision of an eye or for objectively determining a visual axis of an eye and for making the most accurate measurement of refraction. Generally, an optical measuring device or instrument projects laser beams into the eye during a scan. Positions of the projected beams are detected and measured on the retina to produce a set of projections. Wave front tilt of radiation that is backscattered from the retina is calculated as a best fit from the set of projections. The axis of best vision or the visual axis is reconstructed from a set of those traces of chief rays exiting from the eye that cross the nodal point of the optical system of the eye and that are normal to the wave front tilts. Measuring with the Styles Crawford scans centered over this axis provides the most accurate objective refraction.
摘要翻译：提供了用于确定眼睛最佳视力的轴或用于客观地确定眼睛的视轴并且用于进行最准确的折射测量的方法。通常，光学测量装置或仪器在扫描期间将激光束投射到眼睛中。在视网膜上检测和测量投影光束的位置以产生一组投影。从视网膜反向散射的辐射的波前倾斜被计算为来自该组投影的最佳拟合。最佳视力或视轴的轴线是从眼睛中射出的主要射线的一组痕迹重新构成的，这些射线穿过眼睛的光学系统的节点并且与波前倾斜正交。用样式测量以该轴为中心的克劳福德扫描提供最准确的客观折射。

2. 发明申请

US20140160438A1 Methods for Objectively Determining the Visual Axis of the Eye and Measuring Its Refraction 审中-公开
$Methods for Objectively Determining the Visual Axis of the Eye and Measuring Its Refraction$
标题翻译：客观地确定眼睛视轴和测量其折射的方法
公开(公告)号：US20140160438A1
公开(公告)日：2014-06-12
申请号：US14102257
申请日：2013-12-10
申请人： Joe S. Wakil , Paul van Saarloos , Vasyl Molebny , Sergiy Molebny
发明人： Joe S. Wakil , Paul van Saarloos , Vasyl Molebny , Sergiy Molebny
IPC分类号： A61B3/107
CPC分类号： A61B3/107 , A61B3/0025 , A61B3/028 , A61B3/1015 , A61B3/103
摘要： Provided are methods for determining an axis of best vision of an eye or for objectively determining a visual axis of an eye and for making the most accurate measurement of refraction. Generally, an optical measuring device or instrument projects laser beams into the eye during a scan. Positions of the projected beams are detected and measured on the retina to produce a set of projections. Wave front tilt of radiation that is backscattered from the retina is calculated as a best fit from the set of projections. The axis of best vision or the visual axis is reconstructed from a set of those traces of chief rays exiting from the eye that cross the nodal point of the optical system of the eye and that are normal to the wave front tilts. Measuring with the Styles Crawford scans centered over this axis provides the most accurate objective refraction.
摘要翻译：提供了用于确定眼睛最佳视力的轴或用于客观地确定眼睛的视轴并且用于进行最准确的折射测量的方法。通常，光学测量装置或仪器在扫描期间将激光束投射到眼睛中。在视网膜上检测和测量投影光束的位置以产生一组投影。从视网膜反向散射的辐射的波前倾斜被计算为来自该组投影的最佳拟合。最佳视力或视轴的轴线是从眼睛中射出的主要射线的一组痕迹重新构成的，这些射线穿过眼睛的光学系统的节点并且与波前倾斜正交。用样式测量以该轴为中心的克劳福德扫描提供最准确的客观折射。

3. 发明申请

US20160135681A1 Methods for Objectively Determining the Visual Axis of the Eye and Measuring Its Refraction 审中-公开
$Methods for Objectively Determining the Visual Axis of the Eye and Measuring Its Refraction$
标题翻译：客观地确定眼睛视轴和测量其折射的方法
公开(公告)号：US20160135681A1
公开(公告)日：2016-05-19
申请号：US15007921
申请日：2016-01-27
申请人： Joe S. Wakil , Paul van Saarloos , Vasyl Molebny , Sergiy Molebny
发明人： Joe S. Wakil , Paul van Saarloos , Vasyl Molebny , Sergiy Molebny
IPC分类号： A61B3/10 , A61B3/12 , A61F9/008 , A61B3/00
CPC分类号： A61B3/1015 , A61B3/0008 , A61B3/0025 , A61B3/103 , A61B3/107 , A61B3/1225 , A61F9/00802
摘要： Provided herein are methods for objectively determining a visual axis of an eye. An optical axis of a measuring instrument is aligned with an unambiguously determinable axis of the eye which is the pupillary axis crossing the vertex of an anterior surface of a cornea and perpendicular to the vertex. A wave front tilt of radiation of a set of narrow laser beams backscattered from the retina is calculated as a tilt component in a polynomial that describes the wave front. The visual axis is reconstructed from a set of chief rays exiting from the eye after crossing nodal points of the optical system of the eye.
摘要翻译：本文提供了客观地确定眼睛的视轴的方法。测量仪器的光轴与眼睛的明确可确定的轴线对准，眼睛的轴线是与角膜前表面的顶点交叉并垂直于顶点的瞳孔轴线。从描述波前的多项式中的倾斜分量计算出从视网膜反向散射的一组窄激光束的波前倾斜。从穿过眼睛光学系统的节点之后，从眼睛出射的一组主要射线重构视轴。

4. 发明授权

US07303281B2 Method and device for determining refractive components and visual function of the eye for vision correction 有权
$Method and device for determining refractive components and visual function of the eye for vision correction$
标题翻译：用于确定视力矫正的眼睛屈光分量和视觉功能的方法和装置
公开(公告)号：US07303281B2
公开(公告)日：2007-12-04
申请号：US10714454
申请日：2003-11-14
申请人： Youssef S. Wakil , Vasyl Molebny , Ioannis G. Pallikaris , Sergiy Molebny , Tom Padrick
发明人： Youssef S. Wakil , Vasyl Molebny , Ioannis G. Pallikaris , Sergiy Molebny , Tom Padrick
IPC分类号： A61B3/10
CPC分类号： A61B3/1015 , A61B3/0025 , A61B3/103 , A61B3/107
摘要： A method and an instrument is provided for measuring aberration refraction of an eye with a first device for measuring the total aberration refraction of the eye and a second device for measuring the aberration refraction of the cornea of the eye. The component of aberration refraction caused by the lens caused by the lens is calculated using the measured total eye aberration refraction and the measured component of aberration refraction of the cornea mapped over the optical surfaces of the eye. Each component portion of the aberration refraction provides information usable for making appropriate corrective actions at the cornea, at the lens, or both as indicated by the mapped measurements and calculations.
摘要翻译：提供了一种用于测量眼睛的全像差折射的第一装置用于测量眼睛的像差折射的方法和装置，以及用于测量眼睛的角膜的像差折射的第二装置。使用所测量的全部眼球像差折射和映射在眼睛的光学表面上的角膜的像差折射的测量分量来计算由透镜引起的由透镜引起的像差折射的分量。像差折射的每个分量部分提供可用于在角膜，透镜或两者处进行适当校正动作的信息，如由映射的测量和计算所指示的。

5. 发明申请

US20050007551A1 Method and device for determining refractive components and visual function of the eye for vision correction 有权
$Method and device for determining refractive components and visual function of the eye for vision correction$
标题翻译：用于确定视力矫正的眼睛屈光分量和视觉功能的方法和装置
公开(公告)号：US20050007551A1
公开(公告)日：2005-01-13
申请号：US10714454
申请日：2003-11-14
申请人： Youssef Wakil , Vasyl Molebny , Ioannis Pallikaris , Sergiy Molebny , Tom Padrick
发明人： Youssef Wakil , Vasyl Molebny , Ioannis Pallikaris , Sergiy Molebny , Tom Padrick
IPC分类号： A61B20060101 , A61B3/00 , A61B3/10 , A61B3/103 , A61B3/107
CPC分类号： A61B3/1015 , A61B3/0025 , A61B3/103 , A61B3/107
摘要： A method and an instrument is provided for measuring aberration refraction of an eye with a first device for measuring the total aberration refraction of the eye and a second device for measuring the aberration refraction of the cornea of the eye. The component of aberration refraction caused by the lens caused by the lens is calculated using the measured total eye aberration refraction and the measured component of aberration refraction of the cornea mapped over the optical surfaces of the eye. Each component portion of the aberration refraction provides information usable for making appropriate corrective actions at the cornea, at the lens, or both as indicated by the mapped measurements and calculations.
摘要翻译：提供了一种用于测量眼睛的全像差折射的第一装置用于测量眼睛的像差折射的方法和装置，以及用于测量眼睛的角膜的像差折射的第二装置。使用所测量的全部眼球像差折射和映射在眼睛的光学表面上的角膜的像差折射的测量分量来计算由透镜引起的由透镜引起的像差折射的分量。像差折射的每个分量部分提供可用于在角膜，透镜或两者处进行适当校正动作的信息，如由映射的测量和计算所指示的。

6. 再颁专利

USRE42782E1 Method and device for synchronous mapping of the total refraction non-homogeneity of the eye and its refractive components 有权
$Method and device for synchronous mapping of the total refraction non-homogeneity of the eye and its refractive components$
标题翻译：用于同步映射眼睛的全折射非均匀性及其折射分量的方法和装置
公开(公告)号：USRE42782E1
公开(公告)日：2011-10-04
申请号：US10876200
申请日：2004-06-23
申请人： Vasyl Molebny , Ioannis Pallikaris , Youssef Wakil , Sergiy Molebny
发明人： Vasyl Molebny , Ioannis Pallikaris , Youssef Wakil , Sergiy Molebny
IPC分类号： A61B3/10
CPC分类号： A61B3/1015
摘要： An instrument for measuring aberration refraction of an eye is provided, having: a lens system defining an instrument optical axis and an alignment device for aligning the visual axis of the eye with the instrument optical axis. A light source produces a probing beam that is projected through the lens system parallel to the instrument optical axis and is selectably positionable partially off-set from the instrument optical axis for entering the eye parallel to the instrument optical axis at a plurality of locations on the cornea of the eye. A first photodetector measures the position of a first portion of the probing beam light scattered back from the retina of the eye to measure aberration refraction of the eye at a plurality of locations. A second photodetector synchronously measures the position of a second portion of the probing beam light reflected back from the cornea of the eye.
摘要翻译：提供了一种用于测量眼睛的像差折射的仪器，其具有：定义仪器光轴的透镜系统和用于使眼睛的视轴与仪器光轴对准的对准装置。光源产生探测光束，该探测光束平行于仪器光轴投影通过透镜系统，并且可选择地从仪器光轴偏置定位，用于在多个位置上平行于仪器光轴进入眼睛眼角膜第一光电检测器测量从眼睛的视网膜散射回来的探测光束的第一部分的位置，以测量多个位置处的眼睛的像差折射。第二光电检测器同步地测量从眼睛的角膜反射回来的探测光束的第二部分的位置。

7. 发明授权

US07380942B2 Method for measuring the wave aberrations of the eye 失效
标题翻译：测量眼睛波像差的方法
公开(公告)号：US07380942B2
公开(公告)日：2008-06-03
申请号：US10530132
申请日：2003-10-06
申请人： Sergiy Molebny , Vasyl Molebny , LaMar Frederick Laster
发明人： Sergiy Molebny , Vasyl Molebny , LaMar Frederick Laster
IPC分类号： A61B3/14 , A61B3/00
CPC分类号： A61B3/1015
摘要： Provided herein are methods for measuring wave aberrations of the eye. Retinal scattered radiation from a probing laser beam is detected, the wave front tilt is measured as first partial derivatives along known coordinates in a discrete set of the pupil points, the wave front is approximated from this data as functions of the pupil coordinates and the wave aberrations of the eye are thereby calculated. Partial derivatives are determined at any pupil point by spline approximation using the values in a discrete number of points in which the wave front tilts are measured. This set of points may be located along concentric circles or along one of the orthogonal axes. The wave front is reconstructed using numerical integration along the radii with the initial integration point in the center of the pupil. Wave aberrations are calculated from wave front data reconstructed in the form of splines.
摘要翻译：本文提供了测量眼睛波像差的方法。检测到来自探测激光束的视网膜散射辐射，波前倾斜被测量为沿着瞳孔点的离散集合中的已知坐标的第一偏导数，波阵面从该数据近似为瞳孔坐标和波的函数从而计算出眼睛的像差。通过样条逼近，在任何瞳孔点处使用在波前倾斜测量的离散点数中的值来确定部分导数。这组点可以沿同心圆或沿着正交轴之一定位。使用沿着半径的数字积分来重建波前，其初始积分点在瞳孔的中心。波形像差是以样条曲线形式重构的波前数据计算的。

8. 发明授权

US07311400B2 Determining clinical refraction of eye 有权
$Determining clinical refraction of eye$
标题翻译：确定眼睛的临床折射
公开(公告)号：US07311400B2
公开(公告)日：2007-12-25
申请号：US10475153
申请日：2002-04-16
申请人： Youssef Wakil , Vasyl V. Molebny , Sergiy Molebny , Ioannis Pallikaris
发明人： Youssef Wakil , Vasyl V. Molebny , Sergiy Molebny , Ioannis Pallikaris
IPC分类号： A61B3/10
CPC分类号： A61B3/107 , A61B3/022 , A61B3/1015
摘要： Eye refraction is measured to achieve desired quality via a selected vision characteristics. A characteristic of vision is selected to correlate to the desired quality of vision from a group of vision characteristics comprising acuity, Strehl ratio, contrast sensitivity, night vision, day vision, and depth of focus, dynamic refraction over a period of time during focus accommodation, and dynamic refraction over a period of time during pupil constriction and dilation. Wavefront aberration measurements are used to objectively measure the state of the eye refraction that defines the desired vision characteristic. The measured state of refraction is expressed with a mathematical function enabling correction of the pre-selected vision characteristic to achieve the desired quality of vision. The mathematical expression function may be a Zernike polynomial having both second order and higher order terms or a function determined by spline mathematical calculations. Pre-selected vision characteristics may be determined using ray tracing technology.
摘要翻译：通过选择的视觉特性测量眼睛折射以达到期望的质量。视觉特征被选择为与来自一组视力特征（包括敏锐度，Strehl比，对比敏感度，夜视，日视力和焦点深度）的视觉特性相关联，在聚焦住宿期间的一段时间内的动态折射，以及在瞳孔缩窄和扩张期间的一段时间内的动态折射。波前像差测量用于客观测量定义所需视觉特性的眼睛折射状态。测量的折射率用能够校正预先选择的视觉特性以实现期望的视觉质量的数学功能来表示。数学表达式函数可以是具有二阶和高阶项的Zernike多项式或由样条数学计算确定的函数。可以使用光线跟踪技术来确定预先选择的视觉特征。

9. 发明申请

US20060170868A1 Method for measuring the wave aberrations of the eye 失效
标题翻译：测量眼睛波像差的方法
公开(公告)号：US20060170868A1
公开(公告)日：2006-08-03
申请号：US10530132
申请日：2003-10-06
申请人： Sergiy Molebny , Molebny Vasyl , Laster LaMar
发明人： Sergiy Molebny , Molebny Vasyl , Laster LaMar
IPC分类号： A61B3/10 , A61B3/00
CPC分类号： A61B3/1015
摘要： The invention relates to medical instrumentation, in particular to diagnostic measuring devices, and can be applied, for example, for high-accuracy vision correction. This method uses probing the eye with a thin laser beam, detecting the radiation scattered by retina, measuring the wave front tilt in the form of first partial derivatives along the coordinates in a discrete set of the pupil points with known coordinates, approximating the wave front from said data as functions of pupil coordinates and calculating the wave aberrations of the eye. Partial derivatives are determined in any point of the pupil by means of spline approximation using the values in a discrete number of points, in which the wave front tilts are measured. This set of points can be located along concentric circles or along one of the orthogonal axes. The wave front is reconstructed using numerical integration along the radii with the initial integration point in the center of the pupil. The wave aberrations are calculated on base of wave front data reconstructed in the form of splines.
摘要翻译：本发明涉及医疗仪器，特别涉及诊断测量装置，并且可以应用于例如高精度视力矫正。该方法使用细激光束探测眼睛，检测由视网膜散射的辐射，以具有已知坐标的瞳孔点的离散组中的坐标测量以第一偏导数形式的波前倾斜，近似波前从所述数据作为瞳孔坐标的函数并计算眼睛的波像差。通过使用离散数量的点中的值进行样条逼近，在瞳孔的任何点处确定部分导数，其中测量波前倾斜。这组点可以沿同心圆或正交轴之一定位。使用沿着半径的数字积分来重建波前，其初始积分点在瞳孔的中心。基于以样条形式重构的波前数据计算波像差。

10. 发明申请

US20050057723A1 Determining clinical refraction of eye 有权
$Determining clinical refraction of eye$
标题翻译：确定眼睛的临床折射
公开(公告)号：US20050057723A1
公开(公告)日：2005-03-17
申请号：US10475153
申请日：2002-04-16
申请人： Youssef Wakil , Vasyi Molebny , Sergiy Molebny , Ioannis Pallikaris
发明人： Youssef Wakil , Vasyi Molebny , Sergiy Molebny , Ioannis Pallikaris
IPC分类号： A61B3/107 , A61B3/00
CPC分类号： A61B3/107 , A61B3/022 , A61B3/1015
摘要： A method of measuring eye refraction to achieve desired quality according to a selected vision characteristics comprising the steps of selecting a characteristic of vision to correlate to the desired quality of vision from a group of vision characteristics comprising acuity, Strehl ratio, contrast sensitivity, night vision, day vision, and depth of focus, dynamic refraction over a period of time during focus accommodation, and dynamic refraction over a period of time during pupil constriction and dilation; using wavefront aberration measurements to objectively measure the state of the eye refraction that defines the desired vision characteristic; and expressing the measured state of refraction with a mathematical function to enable correction of the pre-selected vision characteristic to achieve the desired quality of vision. The mathematical function of expression may be a Zernike polynomial having both second order and higher order terms or a function determined by spline mathematical calculations. The pre-selected desired vision characteristics may be determined using ray tracing technology.
摘要翻译：一种测量眼睛折射以根据所选择的视觉特征实现期望质量的方法，包括以下步骤：从包括敏锐度，Strehl比，对比敏感度，夜视的视觉特征组中选择视觉特征与期望的视力相关，视力和焦点深度，焦点住宿期间的一段时间的动态折射，以及瞳孔缩小和扩张期间的一段时间的动态折射; 使用波前像差测量来客观地测量定义所需视觉特征的眼睛折射状态; 并用数学函数表达测量的折射状态，以使得能够校正预先选择的视觉特征以实现期望的视觉质量。表达式的数学函数可以是具有二阶和高阶项的Zernike多项式或由样条数学计算确定的函数。可以使用光线跟踪技术来确定预先选择的期望视觉特征。

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