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1. 发明授权

US6149592A Integrated fluoroscopic projection image data, volumetric image data, and surgical device position data 失效
标题翻译：集成荧光投影图像数据，体积图像数据和手术装置位置数据
公开(公告)号：US6149592A
公开(公告)日：2000-11-21
申请号：US980171
申请日：1997-11-26
申请人： Jeffrey H. Yanof , Pieter Gerhard Roos , Kenneth L. Freeman , Joseph S. Deucher , Andrew J. Ivan , Dominic J. Heuscher
发明人： Jeffrey H. Yanof , Pieter Gerhard Roos , Kenneth L. Freeman , Joseph S. Deucher , Andrew J. Ivan , Dominic J. Heuscher
IPC分类号： G01B15/00 , A61B6/03 , A61B6/12 , A61B19/00 , G06T1/00 , H04N7/18 , A61B5/00
CPC分类号： A61B90/36 , A61B6/027 , A61B6/584
摘要： A patient supported on a patient support (12) is moved into a bore (22) of a planning imaging device, such as a CT scanner (20). A three-dimensional diagnostic image in three-dimensional diagnostic image space is generated and stored in a memory (130). The patient is repositioned outside of the bore with a region of interest in alignment with a real time imaging device, such as a fluoroscopic imaging device (40). A surgical planning instrument (60), such as a pointer or biopsy needle (62), is mounted on an articulated arm (64). As the instrument is inserted into the region of interest, fluoroscopic images are generated and stored in a memory (140). The coordinate systems of the CT scanner, the fluoroscopic device, and the surgical instrument are correlated (102, 104, 112, 120) such that the instrument is displayed on both the CT images (134) and the fluoroscopic images (50), such that cursors move concurrently along the fluoroscopic and CT images, and the like. In a preferred embodiment in which the cursor on the CT image display is at an intersection of transverse, sagittal, and coronal planes, the displayed planes change as the cursor moves coordinating the displayed CT image planes with the position of the cursor on the fluoroscopic image.
摘要翻译：支撑在患者支架（12）上的患者被移动到诸如CT扫描器（20）的规划成像装置的孔（22）中。生成三维诊断图像空间中的三维诊断图像并将其存储在存储器（130）中。将患者重新定位在具有与实时成像装置（例如透视成像装置（40））对准的感兴趣区域的孔外。诸如指针或活检针（62）的手术计划仪器（60）安装在关节臂（64）上。当仪器被插入到感兴趣的区域中时，产生荧光图像并将其存储在存储器（140）中。 CT扫描仪，荧光检查装置和手术器械的坐标系相关（102,104,112,120），使得仪器显示在CT图像（134）和透视图像（50）两者上该光标沿荧光镜和CT图像同时移动等。在CT图像显示器上的光标位于横向，矢状和冠状平面的交叉处的优选实施例中，随着光标移动，显示的平面随着光标在荧光镜图像上的位置协调所显示的CT图像平面而变化。

2. 发明授权

US6031888A Fluoro-assist feature for a diagnostic imaging device 失效
公开(公告)号：US6031888A
公开(公告)日：2000-02-29
申请号：US979571
申请日：1997-11-26
申请人： Andrew J. Ivan , Leonard F. Plut , Joseph S. Deucher , Pieter Gerhard Roos , Kenneth L. Freeman , Marc Piscitelli , Dennis K. Everett
发明人： Andrew J. Ivan , Leonard F. Plut , Joseph S. Deucher , Pieter Gerhard Roos , Kenneth L. Freeman , Marc Piscitelli , Dennis K. Everett
IPC分类号： G01B15/00 , A61B6/00 , A61B6/03 , H04N7/18 , G01N23/00
CPC分类号： A61B6/4441 , A61B6/4464
摘要： A frame (A) of a diagnostic imaging device such as a CT scanner or an MRI device has a bore defining a patient examination region (12). A first x-ray source (B) is mounted to a frame (C) for rotation around the examination region (12). An arc of first radiation detectors (14) detects x-rays which have traversed the examination region. A first image reconstruction processor (18) reconstructs a tomographic image representation from signals generated by the first radiation detectors. A fluoroscopy device (D) is mechanically coupled to the diagnostic scanner for generating and displaying at least substantially real-time fluoroscopic projection image representations on a display monitor (60). A second x-ray source (32) transmits x-rays to an amorphous silicon flat panel radiation detector (36). A second image reconstruction processor (58) reconstructs the fluoroscopic projection image representations from signals generated by the flat panel radiation detector (36). A C-arm (30) supports the second x-ray source (32) and the flat panel radiation detector (36) in a plane offset from a plane of the C-arm. A movable mounting structure (E) is mechanically connected with the gantry (A) and the C-arm (30) to move the C-arm between a stored position and an operating position adjacent the bore.

3. 发明授权

US06364526B2 Fluoro-assist feature for a diagnostic imaging device 失效
标题翻译：用于诊断成像设备的氟辅助功能
公开(公告)号：US06364526B2
公开(公告)日：2002-04-02
申请号：US09480514
申请日：2000-01-10
申请人： Andrew J. Ivan , Leonard F. Plut , Joseph S. Deucher , Pieter Gerhard Roos , Kenneth L. Freeman , Marc Piscitelli , Dennis K. Everett
发明人： Andrew J. Ivan , Leonard F. Plut , Joseph S. Deucher , Pieter Gerhard Roos , Kenneth L. Freeman , Marc Piscitelli , Dennis K. Everett
IPC分类号： H05G164
CPC分类号： A61B6/4441 , A61B6/4464
摘要： A frame (A) of a diagnostic imaging device such as a CT scanner or an MRI device has a bore defining a patient examination region (12). A first x-ray source (B) is mounted to a frame (C) for rotation around the examination region (12). An arc of first radiation detectors (14) detects x-rays which have traversed the examination region. A first image reconstruction processor (18) reconstructs a tomographic image representation from signals generated by the first radiation detectors. A fluoroscopy device (D) is mechanically coupled to the diagnostic scanner for generating and displaying at least substantially real-time fluoroscopic projection image representations on a display monitor (60). A second x-ray source (32) transmits x-rays to an amorphous silicon flat panel radiation detector (36). A second image reconstruction processor (58) reconstructs the fluoroscopic projection image representations from signals generated by the flat panel radiation detector (36). A C-arm (30) supports the second x-ray source (32) and the flat panel radiation detector (36) in a plane offset from a plane of the C-arm. A movable mounting structure (E) is mechanically connected with the gantry (A) and the C-arm (30) to move the C-arm between a stored position and an operating position adjacent the bore.
摘要翻译：诸如CT扫描仪或MRI装置的诊断成像装置的框架（A）具有限定了患者检查区域（12）的孔。第一x射线源（B）安装到框架（C）上以围绕检查区域（12）旋转。第一辐射检测器（14）的弧线检测穿过检查区域的X射线。第一图像重建处理器（18）从由第一辐射探测器产生的信号重建断层图像表示。荧光透视装置（D）机械耦合到诊断扫描器，用于在显示监视器（60）上产生和显示至少基本上实时的透视投影图像表示。第二x射线源（32）将x射线透射到非晶硅平板辐射探测器（36）。第二图像重构处理器（58）根据由平板辐射检测器（36）产生的信号重建荧光透视投影图像表示。 C臂（30）在与C形臂的平面偏移的平面中支撑第二x射线源（32）和平板辐射探测器（36）。可移动的安装结构（E）与机架（A）和C形臂（30）机械连接，以将C形臂移动到存储位置和邻近孔的操作位置之间。

4. 发明授权

US5960054A Angiographic system incorporating a computerized tomographic (CT) scanner 失效
标题翻译：结合计算机断层扫描仪（CT）扫描仪的血管造影系统
公开(公告)号：US5960054A
公开(公告)日：1999-09-28
申请号：US978901
申请日：1997-11-26
申请人： Kenneth L. Freeman , John J. Barni , David W. Hoffmeyer , Donald E. Negrelli , Kim S. Luckner , Joseph S. Deucher
发明人： Kenneth L. Freeman , John J. Barni , David W. Hoffmeyer , Donald E. Negrelli , Kim S. Luckner , Joseph S. Deucher
IPC分类号： A61B6/00 , A61B6/03 , A61B6/04 , G06T1/00 , H04N7/18 , H05G1/60
CPC分类号： A61B6/481 , A61B6/032 , A61B6/504 , A61B6/5235 , A61B6/0457
摘要： A gantry (A) has a bore defining a first patient examination region (12). A first x-ray source (B) is mounted to a frame (C) for rotation around the examination region (12). An arc of first radiation detectors (14) detects x-rays which have traversed the examination region. A first image reconstruction processor (18) reconstructs a tomographic image representation from signals generated by the first radiation detectors. An angiographic device (D) is positioned remote from the gantry along a longitudinal axis (25) for generating and displaying angiographic image representations on a display monitor (46). A second examination region is defined along the longitudinal axis (25) between a second x-ray source (36) and an image intensifier tube (38). A second processor (44) reconstructs the angiographic projection image representations from signals generated by the image intensifier tube (38). A C-arm (30) can be suspended from an overhead track (50) for supporting the second x-ray source (36) and the image intensifier tube (38). A common patient support (24-28) extends along the longitudinal axis between the gantry and the angiographic device for positioning a patient within the first and second examination regions. The patient support includes a slide mechanism (60-64) which permits the patient support to be retracted from the gantry. The processors (18, 44) can be a incorporated into a single controller (E) which fuses or combines an image generated by the angiographic imaging subsystem with an image generated by the tomographic imaging subsystem.
摘要翻译：台架（A）具有限定第一患者检查区域（12）的孔。第一x射线源（B）安装到框架（C）上以围绕检查区域（12）旋转。第一辐射检测器（14）的弧线检测穿过检查区域的X射线。第一图像重建处理器（18）从由第一辐射探测器产生的信号重建断层图像表示。血管造影装置（D）沿着纵向轴线（25）远离机架定位，用于在显示监视器（46）上生成和显示血管造影图像表示。沿着第二X射线源（36）和图像增强管（38）之间的纵向轴线（25）限定第二检查区域。第二处理器（44）根据由图像增压管（38）产生的信号重建血管造影投影图像表示。 C臂（30）可以悬挂在用于支撑第二x射线源（36）和图像增压管（38）的架空轨道（50）上。常见的患者支撑件（24-28）沿着纵向轴线延伸在台架和血管造影装置之间，以将患者定位在第一和第二检查区域内。患者支架包括滑动机构（60-64），其允许患者支撑件从机架中缩回。处理器（18,44）可以并入到将由血管造影成像子系统产生的图像与由断层图像子系统生成的图像融合或组合的单个控制器（E）中。

5. 发明授权

US09198633B2 Computed tomography perfusion phantom and method use thereof 有权
标题翻译：计算机断层扫描灌注模型及其方法使用
公开(公告)号：US09198633B2
公开(公告)日：2015-12-01
申请号：US13985179
申请日：2012-07-27
申请人： Kenneth L. Freeman , Stephen P. Dechant
发明人： Kenneth L. Freeman , Stephen P. Dechant
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： A61B6/583 , A61B6/032 , A61B6/481 , A61B6/504 , A61B6/507
摘要： A computed tomography perfusion phantom includes a scanned plane configured to align with an imaging plane of a CT device. A sample rod extends through the scan plane and includes a plurality of adjacent cells. The plurality of adjacent cells are each constructed of materials having predetermined CT numbers and the plurality of adjacent cells include cell of a plurality of CT numbers. A drive motor is coupled to the sample rod and the drive motor moves the sample rod through the scan plane. A method of calibrating a CT device with the perfusion phantom includes aligning the scan plane of the perfusion phantom with an imaging plane of the CT device. The drive motor moves the sample rod through the scan plane of the perfusion phantom. A plurality of CT number measurements of the sample rod are acquired through the scanned plane of the perfusion phantom.
摘要翻译：计算机断层摄影灌注模型包括配置成与CT装置的成像平面对准的扫描平面。样品杆延伸穿过扫描平面并且包括多个相邻的单元。多个相邻单元各自由具有预定CT编号的材料构成，并且多个相邻单元包括多个CT编号的单元。驱动马达与样品杆相连，驱动马达将样品棒移动通过扫描平面。使用灌注体模校准CT装置的方法包括将灌注体模的扫描平面与CT装置的成像平面对准。驱动电机将样品棒移动通过灌注模型的扫描平面。通过灌注模型的扫描平面获取样品棒的多个CT数量测量值。

6. 发明申请

US20140133636A1 Computed Tomography Perfusion Phantom and Method Use Thereof 有权
标题翻译：计算机断层扫描灌注幻影及其使用方法
公开(公告)号：US20140133636A1
公开(公告)日：2014-05-15
申请号：US13985179
申请日：2012-07-27
申请人： Kenneth L. Freeman , Stephen P. Dechant
发明人： Kenneth L. Freeman , Stephen P. Dechant
IPC分类号： A61B6/00
CPC分类号： A61B6/583 , A61B6/032 , A61B6/481 , A61B6/504 , A61B6/507
摘要： A computed tomography perfusion phantom includes a scanned plane configured to align with an imaging plane of a CT device. A sample rod extends through the scan plane and includes a plurality of adjacent cells. The plurality of adjacent cells are each constructed of materials having predetermined CT numbers and the plurality of adjacent cells include cell of a plurality of CT numbers. A drive motor is coupled to the sample rod and the drive motor moves the sample rod through the scan plane. A method of calibrating a CT device with the perfusion phantom includes aligning the scan plane of the perfusion phantom with an imaging plane of the CT device. The drive motor moves the sample rod through the scan plane of the perfusion phantom. A plurality of CT number measurements of the sample rod are acquired through the scanned plane of the perfusion phantom.
摘要翻译：计算机断层摄影灌注模型包括配置成与CT装置的成像平面对准的扫描平面。样品杆延伸穿过扫描平面并且包括多个相邻的单元。多个相邻单元各自由具有预定CT编号的材料构成，并且多个相邻单元包括多个CT编号的单元。驱动马达与样品杆相连，驱动马达将样品棒移动通过扫描平面。使用灌注体模校准CT装置的方法包括将灌注体模的扫描平面与CT装置的成像平面对准。驱动电机将样品棒移动通过灌注模型的扫描平面。通过灌注模型的扫描平面获取样品棒的多个CT数量测量值。

7. 发明授权

US06366796B1 Method and apparatus for planning brachytherapy surgical procedures 失效
标题翻译：用于规划近距离放射治疗手术的方法和装置
公开(公告)号：US06366796B1
公开(公告)日：2002-04-02
申请号：US09426929
申请日：1999-10-22
申请人： Jeffrey M. Yanof , Kenneth L. Freeman , Barry L. Werner
发明人： Jeffrey M. Yanof , Kenneth L. Freeman , Barry L. Werner
IPC分类号： A61B505
CPC分类号： A61N5/103 , A61B34/10 , A61B90/36 , A61B2017/3411 , A61N5/1001 , A61N2005/1012 , A61N2005/1061
摘要： A tomographic scanner includes an imaging device for obtaining images of the anatomy of a patient. A localizer device such as an articulated arm includes a base portion mounted in a fixed relationship to the imaging device and a free end adapted for selective movement into varied positions near a patient body disposed on the imaging device. A guide device such as grid lattice is attached to the free end of the arm. A position transducer associated with the localizer device generates information as to the position of the localizer and hence the position of the guide device in scanner coordinates. The guide device contains a plurality of needle guides. The position of the guide device is displayed in relation to images of the anatomy of the patient. This information is used by the operator to guide the insertion of brachytherapy seeds in a desired pattern and location in relation to the anatomy of the patient.
摘要翻译：断层扫描仪包括用于获得患者解剖结构的图像的成像装置。诸如关节臂的定位器装置包括以与成像装置固定的关系安装的基部，以及适于选择性地移动到设置在成像装置上的患者身体附近的不同位置的自由端。诸如栅格的引导装置附接到臂的自由端。与定位器装置相关联的位置传感器产生关于定位器的位置的信息，并因此产生导向装置在扫描器坐标中的位置的信息。引导装置包含多个针引导件。相对于患者的解剖结构的图像显示引导装置的位置。操作者使用该信息来指导将近距离放射治疗种子插入相对于患者的解剖结构的期望的图案和位置。

8. 发明授权

US5841830A 3D CT fluoroscopy 失效
标题翻译： 3D CT透视
公开(公告)号：US5841830A
公开(公告)日：1998-11-24
申请号：US802618
申请日：1997-02-19
申请人： John J. Barni , Kenneth L. Freeman , Gary A. Kaufmann , Darrell M. Smith
发明人： John J. Barni , Kenneth L. Freeman , Gary A. Kaufmann , Darrell M. Smith
IPC分类号： A61B6/03 , G06T1/00 , G06T11/00
CPC分类号： A61B6/032 , A61B6/4085 , G06T11/005 , A61B10/0233 , A61B6/027 , A61B90/11 , G06T2211/428 , Y10S378/901
摘要： A radiation source which generates a radiation cone-beam (14) and a two-dimensional radiation detector are spiralled continuously around and longitudinally relative to an imaging volume. Image data from the two-dimensional display is reconstructed (30.sub.1, 30.sub.2, . . . 30.sub.n) into a volumetric, physiological image stored in a subject memory (32). During an interventional surgical procedure with a surgical instrument (42), the x-ray source is gated to operate intermittently, e.g., at 60.degree. angular intervals, at a reduced radiation intensity by an x-ray tube control (40). The additional data is reconstructed into a three-dimensional image representation of the surgical instrument and stored in an instrument memory (34). An operator image selection processor (60) causes data retrieval circuits (62a, 62b) to retrieve like slices or other image representations from the subject and instrument memories. The retrieved data is combined (64) such that a resultant human-readable display (68) shows the instrument superimposed on the anatomical image. The surgical instrument volumetric image is continuously updated such that the display represents a real time display of the surgical instrument illustrating its advancement through the imaging region.
摘要翻译：产生辐射锥形束（14）和二维辐射检测器的辐射源相对于成像体积连续地围绕并且纵向地螺旋化。来自二维显示器的图像数据被重建（301,302，...，30n）成存储在被摄体存储器（32）中的体积生理图像。在用外科器械（42）进行的介入手术过程中，x射线源通过X射线管控制（40）以较低的辐射强度选通间歇地操作，例如以60°角间隔进行操作。附加数据被重建成手术器械的三维图像表示并存储在仪器存储器（34）中。操作员图像选择处理器（60）使得数据检索电路（62a，62b）从对象和仪器存储器中检索类似的切片或其他图像表示。所检索的数据被组合（64），使得所得到的人类可读显示器（68）示出了叠加在解剖图像上的仪器。手术器械体积图像被连续地更新，使得显示器表示外科器械的实时显示，说明其通过成像区域的进展。

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