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1. 发明申请

US20060193778A1 Receptor-mediated uptake of peptides that bind the human transferrin receptor 审中-公开
公开(公告)号：US20060193778A1
公开(公告)日：2006-08-31
申请号：US10806477
申请日：2004-03-23
申请人： Jeffrey Engler , Jae Lee , James Collawn , Bryan Moore
发明人： Jeffrey Engler , Jae Lee , James Collawn , Bryan Moore
IPC分类号： A61K49/00 , A61K38/08 , A61K39/00
CPC分类号： C40B40/02 , A61K47/6425 , A61K47/644 , C07K7/06 , C07K7/08 , C07K2319/00 , C12N15/1037
摘要： Peptides have been discovered which are capable of binding to and internalizing with the human transferrin receptor (hTfR). The sequences HAIYPRH (Seq. ID No. 1) and THRPPMWSPVWP (Seq. ID No. 2) are capable of binding to and internalizing with the human transferrin receptor. When these molecules were fused with other molecules, the fusion product was internalized in cells expressing hTfR. The sequences have use for targeting other peptides and proteins into cells expressing hTfR.

2. 发明申请

US20060070395A1 Refrigerator 审中-公开
标题翻译：冰箱
公开(公告)号：US20060070395A1
公开(公告)日：2006-04-06
申请号：US11143458
申请日：2005-06-03
申请人： Jae Lee , Jae Lee , June Min
发明人： Jae Lee , Jae Lee , June Min
IPC分类号： F25D17/04 , F25D17/06
CPC分类号： F25D17/045 , F25D17/062 , F25D2317/0665 , F25D2317/067 , F25D2500/02
摘要： A refrigerator capable of adjusting a discharge position and a quantity of cold air discharged into the refrigerator. The refrigerator includes an inner panel installed at a rear surface of a storage chamber and having cold air outlets for forming a cooling channel. The refrigerator also includes a variable duct installed at one of the cold air outlets such that the variable duct can move back and forth to vary a length of the cooling channel, and a plurality of cold air distribution holes formed in the variable duct.
摘要翻译：一种能够调节排出位置的冰箱以及排入冰箱的冷气的量。冰箱包括安装在存储室的后表面的内板，并具有用于形成冷却通道的冷气出口。冰箱还包括安装在一个冷气出口处的可变管道，使得可变管道可前后移动以改变冷却通道的长度，以及形成在可变管道中的多个冷气分配孔。

3. 发明申请

US20080036055A1 Semiconductor package and method of making using leadframe having lead locks to secure leads to encapsulant 有权
标题翻译：半导体封装和使用具有引线锁的引线框的方法，以将引线固定到密封剂
公开(公告)号：US20080036055A1
公开(公告)日：2008-02-14
申请号：US11365246
申请日：2006-03-01
申请人： Jae Yee , Young Chung , Jae Lee , Terry Davis , Chung Han , Jae Ku , Jae Kwak , Sang Ryu
发明人： Jae Yee , Young Chung , Jae Lee , Terry Davis , Chung Han , Jae Ku , Jae Kwak , Sang Ryu
IPC分类号： H01L23/495 , H01L21/98
CPC分类号： H01L23/3107 , H01L23/4951 , H01L23/49541 , H01L23/49548 , H01L23/49551 , H01L24/32 , H01L24/48 , H01L24/73 , H01L2224/05599 , H01L2224/29007 , H01L2224/32014 , H01L2224/32245 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2224/85399 , H01L2924/00014 , H01L2924/01006 , H01L2924/01013 , H01L2924/01027 , H01L2924/01033 , H01L2924/01047 , H01L2924/0106 , H01L2924/01075 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/07802 , H01L2924/12042 , H01L2924/15311 , H01L2924/181 , H01L2924/00012 , H01L2924/3512 , H01L2924/00 , H01L2224/45015 , H01L2924/207 , H01L2224/45099
摘要： A lead frame for making a semiconductor package is disclosed. The leadframe's leads include a lead lock provided at a free end of each inner lead that is adapted to increase a bonding force of the inner lead to a resin encapsulate, thereby effectively preventing a separation of the inner lead from occurring in a singulation process involved in the fabrication of the semiconductor package. A semiconductor package fabricated using the lead frame and a fabrication method for the semiconductor package are also disclosed. The lead frame includes a paddle, a plurality of tie bars for supporting the corners of the paddle, a plurality of leads arranged at each of four sides or two facing sides of the paddle in such a fashion that they are spaced apart from an adjacent side of the paddle while extending perpendicularly to the associated side of the paddle, each of the leads having lead separation preventing means adapted to increase a bonding force of the lead to a resin encapsulate subsequently molded to encapsulate the lead frame for fabrication of the semiconductor package, and dam bars for supporting the leads and the tie bars. Additional package embodiments include exposed protrusions extending downward from the leads. The exposed protrusions are irradiated with a laser to remove set resin prior to a solder ball attachment step.
摘要翻译：公开了一种用于制造半导体封装的引线框架。引线框架的引线包括提供在每个内引线的自由端处的引线锁，其适于增加内引线与树脂封装件的结合力，从而有效地防止内引线的分离在所涉及的单个加工过程中发生制造半导体封装。还公开了使用引线框制造的半导体封装和用于半导体封装的制造方法。引线框架包括桨，用于支撑桨的角的多个连杆，多个引线，其布置在桨的四个侧面或两个相对的侧面中，使得它们与相邻侧面间隔开的叶片，同时垂直于桨叶的相关侧延伸，每个引线具有引线分离防止装置，其适于增加引线与随后模制的树脂封装件的结合力，以封装引线框架以制造半导体封装，和用于支撑引线和连接条的阻挡条。另外的封装实施例包括从引线向下延伸的暴露突起。在焊球附着步骤之前，用激光照射暴露的突起以去除固化树脂。

4. 发明申请

US20080014462A1 ORGANIC EL DEVICE 有权
标题翻译：有机EL设备
公开(公告)号：US20080014462A1
公开(公告)日：2008-01-17
申请号：US11861595
申请日：2007-09-26
申请人： Myung KIM , Hyung Oh , Jae Kyung , Sung Kim , Jae Lee , Young Han , Chun Park , Jong Yoon , Sae Park
发明人： Myung KIM , Hyung Oh , Jae Kyung , Sung Kim , Jae Lee , Young Han , Chun Park , Jong Yoon , Sae Park
IPC分类号： B32B9/00
CPC分类号： H01L51/5088 , H01L51/0052 , H01L51/0059 , H01L2251/5346 , Y10S428/917
摘要： An organic EL device is disclosed, which has an organic multilayer between a first electrode and a second electrode, the organic multilayer comprising a hole injection layer formed on the first electrode, and formed of a mixture of at least one selected from organic materials and at least one selected from inorganic materials; a hole transport layer having at least one layer on the hole injection layer; and an emitting layer formed on the hole transport layer.
摘要翻译：公开了一种有机EL器件，其在第一电极和第二电极之间具有有机多层，所述有机层包含在第一电极上形成的空穴注入层，并且由选自有机材料中的至少一种和至少一种选自无机材料; 在空穴注入层上具有至少一层的空穴传输层; 以及形成在空穴传输层上的发光层。

5. 发明申请

US20080006048A1 ICE TRAY ASSEMBLY AND REFRIGERATOR HAVING THE SAME 审中-公开
标题翻译：冰箱组件和具有相同功能的冰箱
公开(公告)号：US20080006048A1
公开(公告)日：2008-01-10
申请号：US11770526
申请日：2007-06-28
申请人： Jong YOON , Byeong Kang , Young Woo Kim , Sang Park , Jae Lee
发明人： Jong YOON , Byeong Kang , Young Woo Kim , Sang Park , Jae Lee
IPC分类号： F25C1/22
CPC分类号： F25D23/04 , F25C1/24 , F25C2305/022 , F25C2400/06 , F25C2400/12 , F25C2400/14 , F25C2500/06 , F25D2323/122
摘要： An ice tray assembly and a refrigerator having the same are disclosed. The ice tray assembly includes an outer case on which a water container is mounted, and an inner case detachably mounted in the outer case to include ice trays which are supplied with water from the water container. The ice tray assembly includes the inner case which is detachable therefrom, thereby facilitating washing. Further, the ice trays can be supplied with water at once without water leakage and ice cubes made in the ice trays can be separated from the ice trays at once.
摘要翻译：公开了一种冰盘组件及其制造商。冰盘组件包括安装有水容器的外壳和可拆卸地安装在外壳中的内壳，以包括从水容器供应水的冰盘。冰盘组件包括可拆卸的内壳，从而便于洗涤。此外，冰盘可以一次供水，没有漏水，冰盘中制成的冰块可以与冰盘一次分离。

6. 发明申请

US20080001556A1 Circuit and method for sensing open-circuit lamp of a backlight unit and display device with circuit for sensing open-circuit lamp of backlight unit 有权
标题翻译：用于感测背光单元的开路灯和用于感测背光单元的开路灯的显示装置的电路和方法
公开(公告)号：US20080001556A1
公开(公告)日：2008-01-03
申请号：US11898312
申请日：2007-09-11
申请人： Hyun-Il Shin , Jae Lee , Chang-Ho Lee
发明人： Hyun-Il Shin , Jae Lee , Chang-Ho Lee
IPC分类号： H05B41/36
CPC分类号： H05B41/2855 , H05B37/03
摘要： A circuit for sensing an open-circuit lamp is provided. The circuit includes a reference voltage output unit, a voltage sensor, and a comparator. The reference voltage output unit provides a reference voltage. The voltage sensor detects a sensed voltage corresponding to a status of a lamp. The status of the lamp includes an open-circuit status and a closed-circuit status. The comparator compares the sensed voltage with the reference voltage and outputs a result indicating the status of the lamp.
摘要翻译：提供了用于感测开路灯的电路。电路包括参考电压输出单元，电压传感器和比较器。参考电压输出单元提供参考电压。电压传感器检测对应于灯状态的感测电压。灯的状态包括开路状态和闭路状态。比较器将检测到的电压与参考电压进行比较，并输出指示灯状态的结果。

7. 发明申请

US20070298129A1 Compounds and compositions for treating neuronal death or neurological dysfunction 审中-公开
标题翻译：用于治疗神经元死亡或神经功能障碍的化合物和组合物
公开(公告)号：US20070298129A1
公开(公告)日：2007-12-27
申请号：US11804588
申请日：2007-05-18
申请人： Byoung Gwag , Young Lee , Jin Shin , Sung Cho , Jae Noh , Jae Cho , Ki Kim , Hyang Lim , Jae Lee , Han Byun , Sun Ko , Sun Son , Sun Park
发明人： Byoung Gwag , Young Lee , Jin Shin , Sung Cho , Jae Noh , Jae Cho , Ki Kim , Hyang Lim , Jae Lee , Han Byun , Sun Ko , Sun Son , Sun Park
IPC分类号： A61K33/00 , A61K31/196 , A61P25/00 , A61P25/16 , A61P25/28 , C07C229/56
CPC分类号： A61K31/137 , A61K31/195 , A61K31/24 , A61K31/60 , A61K33/00 , A61K45/06 , A61K2300/00
摘要： The present invention relates to 2-hydroxy-alkylamino-benzoic acid derivatives and to a combination of cell necrosis inhibitor and lithium, process for the preparation of the derivatives or the combination, pharmaceutical formulation containing the derivatives or the combination, and use of the derivatives or the combination by either concomitant or sequential administration for improvement of treatment of neuronal death or neurological dysfunction. The derivatives and the combination of the present invention are useful for treating neurological diseases, such as amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), spinal muscular atrophy, Alzheimer's disease, Parkinson's disease, Huntington's disease, stroke, traumatic brain injury or spinal cord injury; and for treating ocular diseases such as glaucoma, diabetic retinopathy or macular degeneration.
摘要翻译：本发明涉及2-羟基 - 烷基氨基 - 苯甲酸衍生物和细胞坏死物抑制剂与锂的组合，制备衍生物或组合的方法，含有衍生物或组合的药物制剂及其衍生物的用途或通过伴随或连续施用来改善神经元死亡或神经功能障碍的治疗的组合。本发明的衍生物和组合可用于治疗神经系统疾病，例如肌萎缩性侧索硬化（ALS，Lou Gehrig's disease），脊髓性肌萎缩症，阿尔茨海默氏病，帕金森病，亨廷顿病，中风，创伤性脑损伤或脊髓伤害并用于治疗眼部疾病如青光眼，糖尿病性视网膜病变或黄斑变性。

8. 发明申请

US20070257404A1 Polyester Conjugated Yarn Having High Self-Crimping Properties and Method of Manufacturing the Same 审中-公开
标题翻译：具有高自卷曲性能的聚酯共轭纱线及其制造方法
公开(公告)号：US20070257404A1
公开(公告)日：2007-11-08
申请号：US10554329
申请日：2004-04-21
申请人： Do Kim , Jae Lee , Sun Kim , Young Choi
发明人： Do Kim , Jae Lee , Sun Kim , Young Choi
IPC分类号： D01F8/14
CPC分类号： D01F8/14
摘要： Disclosed is a polyester conjugated yarn, including two types of polymers having a large intrinsic viscosity difference subjected to bi-component spinning so as to be longitudinally arranged in a side-by-side sectional structure, in which the twp types of polymers are polyethyleneterephthalate having intrinsic viscosity of 0.45-0.65 as a first polymer and polytrimethyleneterephthalate having intrinsic viscosity of 0.90-1.10 as a second polymer. The polyester conjugated yarn is advantageous in terms of superior spinnability and high uniformity index. In addition, the polyester conjugated yarn can exhibit high self-crimping properties through relaxation-heat treatment of the dyeing and finishing process, and as well, can be applied to manufacture woven/knit fabrics having softness to the touch, beautiful colors, and high drapery and bulk properties, due to inherent characteristics of polytrimentyleneterephthalate.
摘要翻译：公开了一种聚酯复合纱线，其包括两种类型的具有特征粘度差的聚合物，其经受双组分纺丝以纵向布置成并排剖面结构，其中twp类型的聚合物是聚对苯二甲酸乙二醇酯，其具有作为第一聚合物的特性粘度为0.45-0.65，特性粘度为0.90-1.10的聚三亚甲基对苯二甲酸酯作为第二聚合物。聚酯复合纱在优异的可纺性和高均匀性指数方面是有利的。此外，聚酯复合纱可以通过染色和整理过程的松弛热处理显示出高的自卷曲性，并且还可以应用于制造具有触感柔软度，美丽的颜色和高度的编织/针织织物由于聚对苯二甲酸对苯二甲酸酯的固有特性，帷幔和散装性能。

9. 发明申请

US20070249818A1 Method for the Preparation of 2'-Deoxy-2',2'-Difluorocytidine 失效
标题翻译： 2'-脱氧-2'，2'-二氟胞苷的制备方法
公开(公告)号：US20070249818A1
公开(公告)日：2007-10-25
申请号：US11573869
申请日：2003-12-29
申请人： Jaeheon Lee , Gha Seung Park , Moonsub Lee , Hyo-Jeong Bang , Jae Lee , Cheol Kim , Chang-Ju Choi , Han Kyong Kim , Hoe Chul Lee , Young-Kil Chang , Gwan Lee
发明人： Jaeheon Lee , Gha Seung Park , Moonsub Lee , Hyo-Jeong Bang , Jae Lee , Cheol Kim , Chang-Ju Choi , Han Kyong Kim , Hoe Chul Lee , Young-Kil Chang , Gwan Lee
IPC分类号： C07H19/00
CPC分类号： C07H19/04 , Y02P20/55
摘要： This invention relates to an improved method for stereoselectively preparing 2¢¥-deoxy-2¢¥,2¢¥-difluorocytidine of formula (I), which comprises the steps of reacting a 1-halo ribofuranose compound of formula (III) with a nucleobase of formula (IV) in a solvent to obtain a nucleoside of formula (II) with removing the silyl halide of formula (V) produced during the reaction; and deprotecting the nucleoside of formula (II) to obtain 2¢¥-deoxy-2¢¥,2¢¥-difluorocytidine of formula (I).
摘要翻译：本发明涉及一种用于立体选择性制备式（I）的2'-二脱氧-2¢¥，2¢-二氟胞苷的改进方法，其包括以下步骤：使式（III）的1-卤代呋喃核糖化合物与（IV）的核碱基在溶剂中得到式（II）的核苷，同时除去反应中产生的式（Ⅴ）的甲硅烷基卤化物; 并使式（II）的核苷脱保护，得到式（I）的2¢¥脱氧-2¢¥，2¢¥ - 二氟胞苷。

10. 发明申请

US20070241676A1 Organic electroluminescence device and method for fabricating the same 有权
标题翻译：有机电致发光元件及其制造方法
公开(公告)号：US20070241676A1
公开(公告)日：2007-10-18
申请号：US11783825
申请日：2007-04-12
申请人： Sang Park , Myung Kim , Jae Lee , Eun Cha , Sung Pieh , Kyung Lee , Chang Sung
发明人： Sang Park , Myung Kim , Jae Lee , Eun Cha , Sung Pieh , Kyung Lee , Chang Sung
IPC分类号： H01L51/54 , H01L51/52
CPC分类号： H01L51/5096 , H01L51/5044 , Y10T428/24942 , Y10T428/2495
摘要： Disclosed herein is an organic electroluminescent (EL) device comprising an intermediate layer made of at least one selected from a hole blocking material and an electron blocking material.
摘要翻译：本文公开了一种有机电致发光（EL）装置，其包括由选自空穴阻挡材料和电子阻挡材料中的至少一种制成的中间层。

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