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1. 发明授权

US5726167A Inhibition of phosphatidylinositol 3-kinase with viridin, demethoxyviridin, viridiol, demethoxyviridiol, virone, wortmannolone, and analogs thereof 失效
标题翻译：抑制磷脂酰肌醇3-激酶与维生素D，脱甲氧基维生素，维迪利醇，脱甲氧基维地里多，维罗酮，麦芽酮糖醇及其类似物
公开(公告)号：US5726167A
公开(公告)日：1998-03-10
申请号：US805704
申请日：1997-02-25
申请人： Jeffrey A. Dodge , Masahiko Sato , Chris J. Vlahos
发明人： Jeffrey A. Dodge , Masahiko Sato , Chris J. Vlahos
IPC分类号： A61K31/34 , A61K31/58 , A61K31/585 , A61P35/00 , C07J71/00
CPC分类号： A61K31/585 , A61K31/58
摘要： Viridin, viridiol, demethoxyviridin, demethoxyviridiol, virone, and wortmannolone, and analogs thereof, are inhibitors of phosphatidylinositol 3-kinase. The compounds are particularly useful for inhibiting phosphatidylinositol 3-kinase in vertebrates and for treating phosphatidylinositol 3-kinase-dependent conditions, especially neoplasms, restenosis and atherosclerosis, and bone disorders in vertebrates.
摘要翻译：维琳蛋白，维迪灵，脱甲氧基紫菜素，脱甲氧基维地里醇，维罗酮和麦芽糖酮及其类似物是磷脂酰肌醇3-激酶的抑制剂。该化合物特别可用于在脊椎动物中抑制磷脂酰肌醇3-激酶，并用于治疗磷脂酰肌醇3-激酶依赖性病症，特别是肿瘤，再狭窄和动脉粥样硬化以及脊椎动物中的骨骼疾病。

2. 发明授权

US5468773A Methods for inhibiting bone loss and cartilage degradation using wortmannin and its analogs 失效
标题翻译：使用渥曼青霉素及其类似物抑制骨丢失和软骨降解的方法
公开(公告)号：US5468773A
公开(公告)日：1995-11-21
申请号：US259315
申请日：1994-06-13
申请人： Jeffrey A. Dodge , Masahiko Sato
发明人： Jeffrey A. Dodge , Masahiko Sato
IPC分类号： C12P33/00 , A61K31/365 , A61K31/58 , A61P1/00 , A61P3/00 , A61P19/10 , C07J73/00 , C12R1/80 , A61K31/34
CPC分类号： A61K31/365
摘要： Wortmannin and certain of its analogs are inhibitors of bone loss/bone resorption and cartilage degradation.
摘要翻译：渥曼青霉素及其某些类似物是骨丢失/骨吸收和软骨降解的抑制剂。

3. 发明授权

US5545635A Inhibiting bone loss with equilenin 失效
标题翻译：用平衡抑制骨丢失
公开(公告)号：US5545635A
公开(公告)日：1996-08-13
申请号：US448061
申请日：1995-05-23
申请人： Henry U. Bryant , Jeffrey A. Dodge , Masahiko Sato , Na N. Yang
发明人： Henry U. Bryant , Jeffrey A. Dodge , Masahiko Sato , Na N. Yang
IPC分类号： A61K31/565 , A61P3/00 , A61P19/10 , A61P43/00 , C07J1/00 , A61K31/56
CPC分类号： A61K31/566 , A61K31/565 , A61K31/567
摘要： The present invention provides methods of inhibiting bone loss in humans comprising administering to a patient in need of treatment an effective amount of d-equilenin, 17.beta.-dihydroequilenin, and 17.alpha.-dihydroequilenin, and pharmaceutical formulations thereof.
摘要翻译：本发明提供了抑制人类骨丢失的方法，其包括向需要治疗的患者施用有效量的d-平衡蛋白，17β-二氢马来西林和17α-二氢马替林宁及其药物制剂。

4. 发明授权

US5441947A Methods of inhibiting vascular restenosis 失效
标题翻译：抑制血管再狭窄的方法
公开(公告)号：US5441947A
公开(公告)日：1995-08-15
申请号：US111796
申请日：1993-08-25
申请人： Jeffrey A. Dodge , Masahiko Sato
发明人： Jeffrey A. Dodge , Masahiko Sato
IPC分类号： C12P17/18 , A61K31/34 , A61K31/343 , A61K31/365 , A61P9/00 , C07D307/92 , C07D493/06 , A61K31/56
CPC分类号： A61K31/365 , A61K31/34 , Y10S514/929
摘要： Wortmannin and certain of its analogs are inhibitors of restinosis.
摘要翻译：渥曼青霉素及其某些类似物是再狭窄的抑制剂。

5. 发明授权

US11244459B2 Method for segmentation of grayscale images and segmented area tracking 有权
公开(公告)号：US11244459B2
公开(公告)日：2022-02-08
申请号：US16714104
申请日：2019-12-13
申请人： Masahiko Sato , Sachiko Sato , Ann Rancourt
发明人： Masahiko Sato , Sachiko Sato , Ann Rancourt
IPC分类号： G06T7/13 , G06T7/181 , G06T3/40 , G06K9/00 , G06T7/12 , G06T7/246 , G06T7/11 , G06T7/187
摘要： The present invention is directed to a method for segmentation and tracking of objects recorded in a grayscale video stream and three-dimensional image slices obtained from various devices, including microscopes, video cameras, medical apparatus, and remote sensing devices, using an approach to correct background, segment images using an improved approach, track a segmented area by evaluating surrounding information of the area, analyze data, and create archives of video streams or three-dimensional image slices, segmented areas and the results of tracking.

6. 发明授权

US08818218B2 Photosensor and image forming device incorporating the same 有权
标题翻译：包含其的光传感器和图像形成装置
公开(公告)号：US08818218B2
公开(公告)日：2014-08-26
申请号：US13539774
申请日：2012-07-02
申请人： Sohichiroh Naka , Toshio Yanata , Masahiko Sato , Masataka Akaishi , Masafumi Hashiguchi
发明人： Sohichiroh Naka , Toshio Yanata , Masahiko Sato , Masataka Akaishi , Masafumi Hashiguchi
IPC分类号： G03G15/00
CPC分类号： G03G15/5058 , G03G2215/00616 , G03G2215/0132
摘要： A photosensor includes a light emitting element to emit light to a target object, a light receiving element to receive the light emitted from the light emitting element and reflected by the target object, and a circuit board on which the light emitting element and the light receiving element are mounted, including at least one protrusion thereon. The light emitting element and the light receiving element each have a terminal. The at least one protrusion is configured to support one of the light emitting element and the light receiving element in a contact manner in a state that the terminal is electrically connected to the circuit board.
摘要翻译：光传感器包括向目标物体发光的发光元件，用于接收从发光元件发射并被目标物体反射的光的光接收元件，以及发光元件和光接收的电路板元件被安装，其上包括至少一个突起。发光元件和光接收元件各自具有端子。所述至少一个突起构造成在所述端子电连接到所述电路板的状态下以接触方式支撑所述发光元件和所述光接收元件中的一个。

7. 发明授权

US08583877B2 Fiber channel connection storage controller 失效
标题翻译：光纤通道连接存储控制器
公开(公告)号：US08583877B2
公开(公告)日：2013-11-12
申请号：US12564167
申请日：2009-09-22
申请人： Akemi Sanada , Toshio Nakano , Hidehiko Iwasaki , Masahiko Sato , Kenji Muraoka , Kenichi Takamoto , Masaaki Kobayashi
发明人： Akemi Sanada , Toshio Nakano , Hidehiko Iwasaki , Masahiko Sato , Kenji Muraoka , Kenichi Takamoto , Masaaki Kobayashi
IPC分类号： G06F12/14
CPC分类号： G06F21/78 , G06F3/0622 , G06F3/0635 , G06F3/0637 , G06F3/0659 , G06F3/0665 , G06F3/067 , G06F21/6218 , G06F21/6272 , G06F2221/2129 , G06F2221/2141 , G06F2221/2149
摘要： A storage system adapted to be coupled to a plurality of host devices via a fiber channel. The storage system including a plurality of storage devices, at least a portion of the plurality of storage devices corresponding to a logical unit of a plurality of logical units, the logical unit having a logical unit number (LUN). The storage system also including a storage control device having a cache memory and controlling to store data, addressed to the LUN, into the portion of the plurality of storage devices. The storages system also including an input device being adapted to be used to set information, which is used to prevent an unauthorized access to the logical unit and which corresponds to a relationship between a host device of the plurality of host devices and the logical unit.
摘要翻译：一种适于经由光纤通道耦合到多个主机设备的存储系统。所述存储系统包括多个存储装置，所述多个存储装置的至少一部分对应于多个逻辑单元的逻辑单元，所述逻辑单元具有逻辑单元号（LUN）。存储系统还包括具有高速缓存存储器并且控制将存储到LUN的数据存储到多个存储设备的部分中的存储控制设备。所述存储系统还包括适于用于设置信息的输入设备，所述信息用于防止对所述逻辑单元的未经授权的访问，并且对应于所述多个主机设备的主机设备与所述逻辑单元之间的关系。

8. 发明授权

US08566592B2 Authenticating method for short-distance radio devices and a short-distance radio device 有权
公开(公告)号：US08566592B2
公开(公告)日：2013-10-22
申请号：US12662434
申请日：2010-04-16
申请人： Masahiko Sato , Hidekazu Ikeda
发明人： Masahiko Sato , Hidekazu Ikeda
IPC分类号： H04L29/06
CPC分类号： H04W12/06 , H04L9/3273 , H04L63/0869 , H04L2209/80 , H04W84/18
摘要： The invention provides a method for making mutual authentication between short-distance radio devices automatically or after confirmation by users, and a short-distance radio device for realizing the method. In a condition where a plurality of radio devices exist, each of the radio devices comprising a data communicating unit for performing short-distance radio communication and an authenticating unit for performing authentication of the radio device, the authenticating unit performs mutual authentication between two radio devices automatically or after confirmation by users of the radio devices when the two radio devices come closer to each other to such an extent that coverage areas of radio waves generated by the radio devices overlap with each other.

9. 发明申请

US20130217061A1 Apparatus for Systematic Single Cell Tracking of Distinctive Cellular Events 审中-公开
标题翻译：用于系统性单细胞跟踪特异性细胞事件的装置
公开(公告)号：US20130217061A1
公开(公告)日：2013-08-22
申请号：US13880793
申请日：2011-10-07
申请人： Masahiko Sato , Sachiko Sato
发明人： Masahiko Sato , Sachiko Sato
IPC分类号： C12Q1/02
CPC分类号： G01N33/5091 , C12M41/46 , C12Q1/02 , G01N33/5017 , G02B21/367
摘要： An apparatus for quantitative identification of distinctive cellular events occurring in a cell population using a non-fluorescence approach. The apparatus comprises an image acquisition unit having a Differential Interference Contrast microscope with a camera, a light source, an environmental chamber allowing carrying out cell culture of at least one cell in a cell population; the image acquisition unit acquiring images of the cell population, at predetermined time points; a cell tracker for individually tracking the at least one cell of the cell population in the images; a distinctive cellular event detector for detecting an occurrence of a distinctive cellular event; a report generator; wherein the distinctive cellular event is selected from the group consisting of: tripolar, tetrapolar, quadpolar cell division, cell fusion, cell death, impaired cell division, cell shape alteration, nuclear shape alteration, inner cellular material accumulation, cell enlargement, engulfing, hyper-mobilization, hypo-mobilization and prolonged doubling time.
摘要翻译：用于使用非荧光方法定量鉴定发生在细胞群体中的特异性细胞事件的装置。该装置包括具有相机的差分干涉对比显微镜的图像获取单元，光源，允许在细胞群体中进行至少一个细胞的细胞培养的环境室; 所述图像获取单元在预定时间点获取所述细胞群体的图像; 用于单独跟踪图像中的细胞群体的至少一个细胞的细胞跟踪器; 用于检测特征性细胞事件的发生的特征性细胞事件检测器; 报告生成器其中特征性细胞事件选自：三极，四极，四极细胞分裂，细胞融合，细胞死亡，细胞分裂受损，细胞形状改变，核形态改变，内细胞物质积累，细胞增殖，吞噬，超 - 动员不足，延长倍增时间。

10. 发明授权

US08375168B2 Method and system of collection performance data for storage network 失效
标题翻译：存储网络采集性能数据的方法和系统
公开(公告)号：US08375168B2
公开(公告)日：2013-02-12
申请号：US13448057
申请日：2012-04-16
申请人： Naoto Matsunami , Takashi Oeda , Akira Yamamoto , Yasuyuki Mimatsu , Masahiko Sato
发明人： Naoto Matsunami , Takashi Oeda , Akira Yamamoto , Yasuyuki Mimatsu , Masahiko Sato
IPC分类号： G06F12/00
CPC分类号： G06F3/0635 , G06F3/0611 , G06F3/067 , G06F3/0689
摘要： This invention provides a user or an operator with a management apparatus or method for displaying logical connection information between an interface connected to a computer and a switch and a storage system or a logical unit in the storage system in a virtual storage system, wherein the switch receives a first access request from said computer, converts said first access request to a second access request to one of said plural storage systems, and sends said second access request to one of said plural storage systems or one logical unit.
摘要翻译：本发明为用户或操作者提供一种管理装置或方法，用于在连接到计算机的接口与交换机之间显示逻辑连接信息，以及在虚拟存储系统中的存储系统中的存储系统或逻辑单元，其中开关从所述计算机接收第一访问请求，将所述第一访问请求转换为所述多个存储系统之一的第二访问请求，并将所述第二访问请求发送到所述多个存储系统之一或一个逻辑单元。

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