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1. 发明授权

US5348533A Pheresis apparatus 失效
标题翻译：排血装置
公开(公告)号：US5348533A
公开(公告)日：1994-09-20
申请号：US936569
申请日：1992-08-27
申请人： Jean Papillon , Frederick J. York
发明人： Jean Papillon , Frederick J. York
IPC分类号： A61M1/36 , A61M1/00
CPC分类号： A61M1/3693 , A61M1/3696 , A61M1/3643 , A61M2205/3393
摘要： The length of time required to draw, centrifugally separate, harvest blood components and return blood components is reduced by providing a two-arm pheresis system in which blood is drawn from one arm, anticoagulated and pumped into an input reservoir then transferred into a centrifuge bowl for separation, while separated blood components are harvested and returned to the donor from an output reservoir via another arm.
摘要翻译：抽取，离心分离，收集血液成分和返回血液成分所需的时间长短通过提供双臂血液分离系统来减少，其中血液从一只手臂抽出，抗凝和泵入输入储器，然后转移到离心机碗中用于分离，而分离的血液成分被收集并且通过另一个臂从输出储存器返回给供体。

2. 发明授权

US5643193A Apparatus for collection washing and reinfusion of shed blood 失效
标题翻译：用于收集洗涤和输出流血的装置
公开(公告)号：US5643193A
公开(公告)日：1997-07-01
申请号：US571496
申请日：1995-12-13
申请人： Jean Papillon , Etienne Pages
发明人： Jean Papillon , Etienne Pages
IPC分类号： A61M1/02 , A61M1/00 , A61M1/36 , A61M37/00
CPC分类号： A61M1/3693 , A61M1/3621 , A61M1/3692 , A61M1/3696 , A61M1/0011 , A61M2205/3306 , A61M2205/3344 , A61M2205/3351 , A61M2205/3393 , B04B2005/0478
摘要： An integrated, vacuum-driven shed blood processing system that collects, dilutes, filters and washes postoperatively shed blood and concentrates red blood cells for reinfusion to the patient. The location of the centrifuge bowl between the surgical site and the vacuum source used to clean the site allows the immediate collection of shed blood in the bowl without an intermediate reservoir or an additional pump. In conjunction with a modified centrifuge bowl having a sealed aperture in its floor that permits reinfusion directly from the bowl without an additional reinfusion bag or reverse pump, this configuration processes blood for reinfusion using fewer steps and components yet without loss of functionality. Dilution of the blood upon its introduction into the system reduces the tendency to coagulate and allows the use of lower bowl rotation speeds. Slower rotation reduces red blood cell damage and lowers power requirements, which improves portability.
摘要翻译：一个集成的真空驱动的棚式血液处理系统，在术后收集，稀释，过滤和洗涤血液，并将红血细胞浓缩至患者的再灌注。手术部位和用于清洁部位的真空源之间的离心机碗的位置允许在碗中立即收集流出的血液，而不需要中间储存器或额外的泵。结合具有在其地板中具有密封孔的修改的离心机碗，其允许直接从碗再灌输而不需要额外的再灌注袋或反向泵，该配置使用较少的步骤和组件处理血液用于再灌注而不失去功能。血液在引入系统时的稀释降低了凝结的倾向，并允许使用较低的碗转速。较慢的旋转可减少红细胞损伤并降低功率需求，从而提高便携性。

3. 发明授权

US5971948A Apparatus for collection, washing, and reinfusion of shed blood 失效
标题翻译：用于收集，洗涤和输送流血的装置
公开(公告)号：US5971948A
公开(公告)日：1999-10-26
申请号：US818314
申请日：1997-03-14
申请人： Etienne Pages , Jean Papillon
发明人： Etienne Pages , Jean Papillon
IPC分类号： A61M1/02 , A61M1/00 , A61M1/36 , A61M37/00
CPC分类号： A61M1/3693 , A61M1/3621 , A61M1/3692 , A61M1/3696 , A61M1/0011 , A61M2205/3306 , A61M2205/3344 , A61M2205/3351 , A61M2205/3393 , B04B2005/0478
摘要： An integrated, vacuum-driven shed blood processing system that collects, dilutes, filters and washes postoperatively shed blood and concentrates red blood cells for reinfusion to the patient. The location of the centrifuge bowl between the surgical site and the vacuum source used to clean the site allows the immediate collection of shed blood in the bowl without an intermediate reservoir or an additional pump. In conjunction with a modified centrifuge bowl having a sealed aperture in its floor that permits reinfusion directly from the bowl without an additional reinfusion bag or reverse pump, this configuration processes blood for reinfusion using fewer steps and components yet without loss of functionality. Dilution of the blood upon its introduction into the system reduces the tendency to coagulate and allows the use of lower bowl rotation speeds. Slower rotation reduces red blood cell damage and lowers power requirements, which improves portability.
摘要翻译：一个集成的真空驱动的棚式血液处理系统，在术后收集，稀释，过滤和洗涤血液，并将红血细胞浓缩至患者的再灌注。手术部位和用于清洁部位的真空源之间的离心机碗的位置允许在碗中立即收集流出的血液，而不需要中间储存器或额外的泵。结合具有在其地板中具有密封孔的修改的离心机碗，其允许直接从碗再灌输而不需要额外的再灌注袋或反向泵，该配置使用较少的步骤和组件处理血液用于再灌注而不失去功能。血液在引入系统时的稀释降低了凝结的倾向，并允许使用较低的碗转速。较慢的旋转可减少红细胞损伤并降低功率需求，从而提高便携性。

4. 发明授权

US5387187A Red cell apheresis method 失效
标题翻译：红细胞单采法
公开(公告)号：US5387187A
公开(公告)日：1995-02-07
申请号：US203884
申请日：1994-03-01
申请人： Claude Fell , Jean Papillon
发明人： Claude Fell , Jean Papillon
IPC分类号： A61M1/02 , A61M1/30 , A61M1/36 , A61M37/00
CPC分类号： A61M1/3693 , A61M1/30 , A61M1/304 , A61M1/3696 , A61M2205/7518
摘要： The present invention provides an apheresis apparatus and method for separating blood. A phlebotomy needle draws anticoagulated whole blood from a donor into a separation chamber. The separation chamber separates plasma from higher density blood components. The plasma is displaced to a plasma collection bag. The separation process is terminated and the higher density blood components remaining in the separation chamber are diluted with saline solution and are returned to the donor via the phlebotomy needle. Anticoagulated whole blood is drawn again from the donor into the separation chamber. The separation chamber again separates plasma from higher density blood components in the separation chamber. The separation process is then terminated and the donor is disconnected. The higher density blood components remaining in the separation chamber are displaced to a bag for collecting higher density blood components and is rejuvenated with additive solution.
摘要翻译：本发明提供了一种用于分离血液的分离装置和方法。静脉注射针将供体的抗凝血全血抽入分离室。分离室将血浆与较高密度的血液成分分离。将等离子体置换到血浆收集袋。分离过程终止，残留在分离室中的较高密度的血液成分用盐水溶液稀释，并通过静脉注射针返回给供体。抗凝血全血从供体再次抽入分离室。分离室再次将血浆与分离室中较高密度的血液成分分离。然后分离过程终止，供体断开。残留在分离室中的较高密度的血液成分被移动到用于收集较高密度血液成分的袋子中，并且用添加剂溶液进行复原。

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