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1. 发明申请

US20080137936A1 Method for providing a 3D X-ray image dataset of a patient's heart 有权
标题翻译：用于提供患者心脏的3D X射线图像数据集的方法
公开(公告)号：US20080137936A1
公开(公告)日：2008-06-12
申请号：US11980229
申请日：2007-10-30
申请人： Jan Boese , Joachim Hornegger , Gunter Lauritsch , Marcus Prummer
发明人： Jan Boese , Joachim Hornegger , Gunter Lauritsch , Marcus Prummer
IPC分类号： A61B6/00
CPC分类号： G06T7/20 , A61B5/7289 , A61B6/032 , A61B6/466 , A61B6/503 , A61B6/5288 , G06T2207/30048 , Y10S378/901
摘要： X-ray images are recorded of a patient's heart and the heartbeat phase is registered as that is done. The heartbeat phases are coarsely divided into intervals and all X-ray images that have been assigned heartbeat phase from the interval are used for reconstructing a 3D image dataset. The movement fields of the other 3D image datasets are then calculated for one of said 3D image datasets. Movement fields are vector fields indicating the movements of similar structures from one local area to the other. A departure is then made from the coarse interval division, and for each heartbeat phase a movement field is interpolated individually or at least for fairly short intervals from the movement fields determined in advance, which field is used for generating a deformed 3D image dataset that has been imaged onto a reference heartbeat phase. The deformed 3D image datasets are then added together.
摘要翻译：记录患者心脏的X射线图像，并记录心跳阶段。将心跳阶段粗略地划分为间隔，并且已经从间隔分配了心跳相位的所有X射线图像用于重建3D图像数据集。然后针对所述3D图像数据集之一计算其它3D图像数据集的运动场。运动场是指示类似结构从一个局部区域到另一个局部区域的运动的向量场。然后从粗间隔划分出发，并且对于每个心跳阶段，移动场单独或至少相对于预先确定的运动场的相当短的间隔进行内插，该场用于生成变形的3D图像数据集，其具有被成像到参考心跳期。然后将变形的3D图像数据集加在一起。

2. 发明申请

US20080205726A1 Method for providing extended possibilities when imaging a patient's heart 有权
标题翻译：在对患者心脏进行成像时提供扩展可能性的方法
公开(公告)号：US20080205726A1
公开(公告)日：2008-08-28
申请号：US12070884
申请日：2008-02-21
申请人： Jan Boese , Joachim Hornegger , Gunter Lauritsch , Marcus Prummer
发明人： Jan Boese , Joachim Hornegger , Gunter Lauritsch , Marcus Prummer
IPC分类号： G06K9/00
CPC分类号： G06T19/00 , A61B6/4441 , A61B6/486 , A61B6/503 , A61B6/5211 , A61B6/5264 , A61B6/5288 , G06T7/30 , G06T2207/10072 , G06T2207/10116 , G06T2207/10124 , G06T2207/30048 , G06T2210/41
摘要： The invention relates to the use of 2D projection images which belong to a specific common heart phase. A 3D image data set can be used to generate a reference projection image for the same projection angle for each of the 2D projection images and a differential image can be derived from the reference projection image and 2D projection image. The differential images are back-projected and combined in one 3D differential image data set and, by using this, a deformed 3D image data set is obtained from the previously recorded 3D image data set. Iterations guarantee that the deformed 3D image data set ensues with the smallest possible distance from the 2D projection images for the existing common heart phase. Finally, a 3D image data set is available for a different heart phase other than the reference heart phase and the possibilities for imaging a patient's heart are extended.
摘要翻译：本发明涉及属于特定共同心脏相位的二维投影图像的应用。可以使用3D图像数据集来为每个2D投影图像生成用于相同投影角的参考投影图像，并且可以从参考投影图像和2D投影图像导出差分图像。差分图像被反投影并组合在一个3D差分图像数据集中，并且通过使用它，从先前记录的3D图像数据集获得变形的3D图像数据集。迭代保证变形的3D图像数据集随着现有共同心脏相位的2D投影图像的最小可能距离而发生。最后，3D图像数据集可用于除参考心脏相以外的不同心脏相位，并且延长了对患者心脏进行成像的可能性。

3. 发明申请

US20080013675A1 Method for evaluating projection datasets of an object undergoing examination 有权
标题翻译：评估正在进行检查的物体的投影数据集的方法
公开(公告)号：US20080013675A1
公开(公告)日：2008-01-17
申请号：US11824456
申请日：2007-06-29
申请人： Jan Boese , Gunter Lauritsch , Thomas Redel
发明人： Jan Boese , Gunter Lauritsch , Thomas Redel
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/4441 , Y10S378/901
摘要： An object (5) undergoing examination is located within the range of a swiveling axis (4) around which an X-ray source (1) is swiveled during a plurality of mutually discrete swiveling actions. An X-ray detector (2) is swiveled correspondingly so that it will at any time be located diametrically opposite the X-ray source (1) with reference to the swiveling axis (4). Projection datasets (P) of the object (5) undergoing examination are recorded at swiveling angles (α) of the X-ray source (1) during the swiveling actions and stored. Each projection dataset (P) is assigned the respective swiveling angle (α) and a recording instant (t). Together with the swiveling angle (α) assigned to the respective projection dataset (P), each data element of each projection dataset (P) defines a projection line along which an X-ray beam has traveled on its way from the X-ray source (1) to the X-ray detector (2). The projection datasets (P) form recording groups each of which corresponds with the projection datasets (P) that were recorded during a single swiveling action. A computer (15) determines at least one reconstruction group of reconstruction datasets using the projection datasets (P). Each reconstruction dataset contains at least one reconstruction data value assigned to a reconstruction line. Using a temporal interpolation, the computer (15) determines the reconstruction group's reconstruction datasets in such a way that they refer to a uniform reconstruction time. The computer (15) determines a reconstruction of the object (5) undergoing examination using the reconstruction group's reconstruction datasets.
摘要翻译：正在进行检查的物体（5）位于旋转轴线（4）的范围内，在多个相互离散的旋转动作期间，X射线源（1）绕其旋转。 X射线检测器（2）相应地旋转，使得它将随时相对于旋转轴线（4）与X射线源（1）沿径向相对。正在进行检查的物体（5）的投影数据集（P）在旋转动作期间以X射线源（1）的旋转角度（α）记录并存储。每个投影数据集（P）被分配相应的旋转角（α）和记录时刻（t）。与分配给相应的投影数据集（P）的旋转角（α）一起，每个投影数据集（P）的每个数据元素定义了一条投影线，X射线束沿着该投影线从X射线源（1）到X射线检测器（2）。投影数据集（P）形成记录组，每个记录组对应于在单次旋转动作期间记录的投影数据集（P）。计算机（15）使用投影数据集（P）确定重建数据集的至少一个重建组。每个重建数据集包含分配给重建线的至少一个重建数据值。使用时间插值，计算机（15）以这样的方式确定重建组的重建数据集，即它们指的是统一的重建时间。计算机（15）使用重建组的重建数据集确定正在进行检查的对象（5）的重构。

4. 发明申请

US20060067459A1 Method and device for generating a three-dimensional image data record of a moving object by means of X-ray tomography 有权
标题翻译：用于通过X射线层析成像生成运动物体的三维图像数据记录的方法和装置
公开(公告)号：US20060067459A1
公开(公告)日：2006-03-30
申请号：US11238552
申请日：2005-09-29
申请人： Jan Boese , Gunter Lauritsch
发明人： Jan Boese , Gunter Lauritsch
IPC分类号： H05G1/60
CPC分类号： G06T11/005 , A61B5/0402 , A61B5/0456 , A61B5/7207 , A61B6/02 , A61B6/032 , A61B6/503 , A61B6/504 , A61B6/541 , G06T2211/412 , G06T2211/421
摘要： A precise and comparatively simple method for generating a three-dimensional image data record of a moving object using X-ray tomography and a device that is particularly suitable for implementing the method with an X-ray emitter/detector unit supported such that it can be rotated and with an evaluation unit are specified. According to the invention a number of two-dimensional raw images are grouped according to a cyclical relative time at least two preliminary 3D image data records respectively are generated from raw images that correspond to one an-other according to this grouping, at least one movement matrix is derived by comparing two preliminary 3D image data re-cords used as the source data record and the target data record respectively, a 3D image data record with compensation for movement corresponding to a reference time of the source data record is generated by applying the or each movement matrix to the associated target data record and the or each 3D image data record with compensation for movement is added to at least one further 3D image data record with compensation for movement or to another preliminary 3D-image data record corresponding to the same reference time.
摘要翻译：一种用于使用X射线层析成像生成运动物体的三维图像数据记录的精确且相对简单的方法，以及特别适合于利用支持X射线发射器/检测器单元来实现该方法的装置，使得其可以指定了旋转和评估单元。根据本发明，根据循环相对时间对多个二维原始图像进行分组，分别根据该分组从对应于另一个的原始图像生成至少两个初步3D图像数据记录，至少一个运动通过比较分别用作源数据记录和目标数据记录的两个初步3D图像数据重新组合来导出矩阵，通过应用源数据记录的参考时间来对与移动源数据记录的参考时间相对应的移动进行补偿的3D图像数据记录或每个运动矩阵到相关联的目标数据记录，并且具有补偿运动的每个3D图像数据记录被添加到至少一个另外的3D图像数据记录，补偿运动或对应于其的另一预备3D图像数据记录参考时间。

5. 发明申请

US20070030945A1 Operating method for X-ray equipment 有权
标题翻译： X射线设备的操作方法
公开(公告)号：US20070030945A1
公开(公告)日：2007-02-08
申请号：US11400833
申请日：2006-04-07
申请人： Jan Boese , Gunter Lauritsch
发明人： Jan Boese , Gunter Lauritsch
IPC分类号： A61B6/00 , G01N23/00 , G21K1/12 , H05G1/60
CPC分类号： A61B6/4441 , A61B6/503 , A61B6/504 , A61B6/541
摘要： A control device pivots an X-ray arrangement repeatedly between two final angular positions about a pivot axis. It controls the X-ray arrangement such that, respectively at a plurality of angular positions at recording times, projections of an object to be examined arranged in the region of the pivot axis and moving iteratively are detected and supplied to the control device, which stores the projections and the corresponding angular positions. The control device also receives a phase signal referring to the object to be examined and assigns information corresponding to a phase position of the object to be examined to each stored projection. For the reconstruction, a computer selects those projections where the phase position corresponds at least approximately to a reconstruction phase position. For each angular position in which it has selected at least one of the projections the computer checks whether it has selected one or more projections. If the computer has selected a projection for an angular position, it determines this projection as a reconstruction projection. If the computer has selected a plurality of projections for an angular position, it detects the reconstruction projection using these projections. Using the reconstruction projections the computer then detects a three-dimensional reconstruction of the object to be examined.
摘要翻译：控制装置在关于枢转轴线的两个最终角位置之间重复地枢转X射线装置。它控制X射线布置，使得分别在记录时间的多个角位置处检测被布置在枢转轴线的区域并且迭代地移动的被检体的突起并被提供给控制装置，该控制装置存储突起和相应的角位置。控制装置还接收参照被检查对象的相位信号，并将与被检查对象的相位位置对应的信息分配给各存储的投影。对于重建，计算机选择相位位置至少大致对应于重建相位位置的那些投影。对于其中选择至少一个投影的每个角度位置，计算机检查其是否选择了一个或多个投影。如果计算机已经为角位置选择了一个投影，则它将该投影确定为重建投影。如果计算机已经为角位置选择了多个投影，则使用这些投影来检测重建投影。使用重建投影，计算机然后检测待检查对象的三维重建。

6. 发明申请

US20060285632A1 Method and device for reconstructing a 3D image data set of a moving object 有权
标题翻译：用于重建移动物体的3D图像数据集的方法和装置
公开(公告)号：US20060285632A1
公开(公告)日：2006-12-21
申请号：US11453604
申请日：2006-06-15
申请人： Jan Boese , Gunter Lauritsch
发明人： Jan Boese , Gunter Lauritsch
IPC分类号： A61B6/00 , G01N23/00 , G21K1/12 , H05G1/60
CPC分类号： A61B6/032 , A61B6/5217 , A61B6/541 , G06T11/005 , G06T2211/404 , G06T2211/412 , Y10S378/901
摘要： The invention relates to a method and device for reconstructing a 3D image data set of a moving object from a set of projection images, which were recorded at least partially one after the other from different projection directions. The projection images are hereby assigned by ECG gating to a motion phase of the object in each instance and an incomplete 3D image of the object is computed in this motion phase from these few projection images using local tomography. Motion fields are determined from these 3D images and are used during the final 3D image reconstruction for motion corrections.
摘要翻译：本发明涉及一种用于从一组投影图像重建运动物体的3D图像数据集的方法和装置，其从不同的投影方向至少部分地一个接一个地记录。因此，通过ECG门控将投影图像分配给每个实例中的对象的运动相位，并且使用局部断层摄影从这些几个投影图像在该运动相位中计算对象的不完整3D图像。运动场由这些3D图像确定，并在运动校正的最终3D图像重建期间使用。

7. 发明授权

US08103075B2 Method for providing extended possibilities when imaging a patient's heart 有权
标题翻译：在对患者心脏进行成像时提供扩展可能性的方法
公开(公告)号：US08103075B2
公开(公告)日：2012-01-24
申请号：US12070884
申请日：2008-02-21
申请人： Jan Boese , Joachim Hornegger , Günter Lauritsch , Marcus Prümmer
发明人： Jan Boese , Joachim Hornegger , Günter Lauritsch , Marcus Prümmer
IPC分类号： G06K9/00
CPC分类号： G06T19/00 , A61B6/4441 , A61B6/486 , A61B6/503 , A61B6/5211 , A61B6/5264 , A61B6/5288 , G06T7/30 , G06T2207/10072 , G06T2207/10116 , G06T2207/10124 , G06T2207/30048 , G06T2210/41
摘要： The invention relates to the use of 2D projection images which belong to a specific common heart phase. A 3D image data set can be used to generate a reference projection image for the same projection angle for each of the 2D projection images and a differential image can be derived from the reference projection image and 2D projection image. The differential images are back-projected and combined in one 3D differential image data set and, by using this, a deformed 3D image data set is obtained from the previously recorded 3D image data set. Iterations guarantee that the deformed 3D image data set ensues with the smallest possible distance from the 2D projection images for the existing common heart phase. Finally, a 3D image data set is available for a different heart phase other than the reference heart phase and the possibilities for imaging a patient's heart are extended.
摘要翻译：本发明涉及属于特定共同心脏相位的二维投影图像的应用。可以使用3D图像数据集来为每个2D投影图像生成用于相同投影角的参考投影图像，并且可以从参考投影图像和2D投影图像导出差分图像。差分图像被反投影并组合在一个3D差分图像数据集中，并且通过使用它，从先前记录的3D图像数据集获得变形的3D图像数据集。迭代保证变形的3D图像数据集随着现有共同心脏相位的2D投影图像的最小可能距离而发生。最后，3D图像数据集可用于除参考心脏相以外的不同心脏相位，并且延长了对患者心脏进行成像的可能性。

8. 发明授权

US08027526B2 Method for providing a 3D X-ray image dataset of a patient's heart 有权
标题翻译：用于提供患者心脏的3D X射线图像数据集的方法
公开(公告)号：US08027526B2
公开(公告)日：2011-09-27
申请号：US11980229
申请日：2007-10-30
申请人： Jan Boese , Joachim Hornegger , Günter Lauritsch , Marcus Prümmer
发明人： Jan Boese , Joachim Hornegger , Günter Lauritsch , Marcus Prümmer
IPC分类号： A61B6/03
CPC分类号： G06T7/20 , A61B5/7289 , A61B6/032 , A61B6/466 , A61B6/503 , A61B6/5288 , G06T2207/30048 , Y10S378/901
摘要： X-ray images are recorded of a patient's heart and the heartbeat phase is registered as that is done. The heartbeat phases are coarsely divided into intervals and all X-ray images that have been assigned heartbeat phase from the interval are used for reconstructing a 3D image dataset. The movement fields of the other 3D image datasets are then calculated for one of said 3D image datasets. Movement fields are vector fields indicating the movements of similar structures from one local area to the other. A departure is then made from the coarse interval division, and for each heartbeat phase a movement field is interpolated individually or at least for fairly short intervals from the movement fields determined in advance, which field is used for generating a deformed 3D image dataset that has been imaged onto a reference heartbeat phase. The deformed 3D image datasets are then added together.
摘要翻译：记录患者心脏的X射线图像，并记录心跳阶段。将心跳阶段粗略划分为间隔，并且已经从间隔分配了心跳期的所有X射线图像用于重建3D图像数据集。然后针对所述3D图像数据集之一计算其它3D图像数据集的运动场。运动场是指示类似结构从一个局部区域到另一个局部区域的运动的向量场。然后从粗间隔划分出发，并且对于每个心跳阶段，移动场单独或至少相对于预先确定的运动场的相当短的间隔进行内插，该场用于生成变形的3D图像数据集，其具有被成像到参考心跳期。然后将变形的3D图像数据集加在一起。

9. 发明授权

US10719986B2 Method and system for virtual percutaneous valve implantation 有权
公开(公告)号：US10719986B2
公开(公告)日：2020-07-21
申请号：US12975714
申请日：2010-12-22
申请人： Dominik Zaeuner , Razvan Ioan Ionasec , Bogdan Georgescu , Yefeng Zheng , Dorin Comaniciu , Ingmar Voigt , Jan Boese
发明人： Dominik Zaeuner , Razvan Ioan Ionasec , Bogdan Georgescu , Yefeng Zheng , Dorin Comaniciu , Ingmar Voigt , Jan Boese
IPC分类号： G06T17/00 , G06T19/00 , G16H50/50 , G06F19/00
摘要： A method and system for virtual percutaneous valve implantation is disclosed. A patient-specific anatomical model of a heart valve is estimated based on 3D cardiac medical image data and an implant model representing a valve implant is virtually deployed into the patient-specific anatomical model of the heart valve. A library of implant models, each modeling geometrical properties of a corresponding valve implant, is maintained. The implant models maintained in the library are virtually deployed into the patient specific anatomical model of the heart valve to select an implant type and size and deployment location and orientation for percutaneous valve implantation.

10. 发明授权

US09014423B2 Method and system for catheter tracking in fluoroscopic images using adaptive discriminant learning and measurement fusion 有权
标题翻译：使用自适应判别学习和测量融合的荧光镜图像中导管跟踪的方法和系统
公开(公告)号：US09014423B2
公开(公告)日：2015-04-21
申请号：US13412882
申请日：2012-03-06
申请人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： G06K9/00 , A61B6/00 , A61B6/12 , G06T7/20
CPC分类号： A61B6/487 , A61B6/12 , A61B6/503 , G06T7/246 , G06T2207/10016 , G06T2207/10064 , G06T2207/20076 , G06T2207/20081 , G06T2207/30021 , G06T2207/30048
摘要： A method and system for adaptive discriminant learning and measurement fusion for image based catheter tracking is disclosed. An adaptive discriminant model is trained online based on a tracked object, such as a pigtail catheter tip, in at least one previous frame of a fluoroscopic image sequence. The object is tracked in the current frame of the fluoroscopic image sequence based at least on the adaptive discriminant model trained online. The object may be tracked in the current frame based on a fusion of three types of measurement models including the adaptive discriminant model trained online, an object detection model trained offline, and an online appearance model.
摘要翻译：公开了一种用于基于图像的导管跟踪的自适应判别学习和测量融合的方法和系统。在荧光镜像图像序列的至少一个先前帧中，基于跟踪对象（例如尾纤导管尖端）在线训练自适应判别模型。至少基于在线训练的自适应判别模型，在透视图像序列的当前帧中跟踪对象。基于三种类型的测量模型的融合，可以在当前帧中跟踪对象，包括在线训练的自适应判别模型，离线训练的对象检测模型和在线外观模型。

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