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1. 发明授权

US11172960B2 Apparatus and method for septal punch 有权
公开(公告)号：US11172960B2
公开(公告)日：2021-11-16
申请号：US17192329
申请日：2021-03-04
申请人： James S. Gammie , Philip J. Haarstad , David Blaeser , Ryan Bauer , Stephen Roller , Rachael Quinn , Chetan Pasrija , Edwin Hlavka
发明人： James S. Gammie , Philip J. Haarstad , David Blaeser , Ryan Bauer , Stephen Roller , Rachael Quinn , Chetan Pasrija , Edwin Hlavka
IPC分类号： A61B17/34 , A61B17/00
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.

2. 发明申请

US20060089609A1 Devices and methods for tissue modification 有权
公开(公告)号：US20060089609A1
公开(公告)日：2006-04-27
申请号：US11251165
申请日：2005-10-15
申请人： Jeffery Bleich , Edwin Hlavka
发明人： Jeffery Bleich , Edwin Hlavka
IPC分类号： A61M5/32
CPC分类号： A61B17/320758 , A61B17/149 , A61B17/1659 , A61B17/1671 , A61B17/29 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3496 , A61B18/1477 , A61B18/1487 , A61B90/04 , A61B2017/00261 , A61B2017/00287 , A61B2017/003 , A61B2017/00867 , A61B2017/320004 , A61B2017/320044 , A61B2017/32006 , A61B2017/3445 , A61B2017/3447 , A61B2018/1407 , A61B2018/1425 , A61B2090/061 , A61B2090/08021 , A61F2/0045 , A61N1/0551 , A61N1/36017
摘要： Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.

3. 发明授权

US5397335A Trocar assembly with improved adapter seals 失效
标题翻译：具有改进的适配器密封件的套管针组件
公开(公告)号：US5397335A
公开(公告)日：1995-03-14
申请号：US93101
申请日：1993-07-13
申请人： Charles Gresl , Edwin Hlavka
发明人： Charles Gresl , Edwin Hlavka
IPC分类号： A61B17/34 , A61M5/00
CPC分类号： A61B17/3462
摘要： The present invention is directed to a medical device for performing endoscopic procedures comprising a trocar and a cannula assembly having slidable adapter seals. The cannula assembly has a housing at the proximal extracorporeal end of a cannula. A generally semi-circular track follows the periphery of the cannula housing and at least one adapter seal slidably is engaged with the track. The adapter seal comprises a plate that accommodates a sealing element with an aperture for receiving surgical instruments. The adapter seal has engagement means for maintaining the adapter seal in the track. In addition, the adapter seal has releasing means that can be acted upon to apply a countering-force against a tensioning means in order to remove the adapter seal from the cannula assembly.
摘要翻译：本发明涉及一种用于执行内窥镜手术的医疗装置，其包括具有可滑动的适配器密封件的套针针和插管组件。套管组件在套管的近端体外端具有壳体。大致半圆形的轨道跟随插管壳体的周边，并且至少一个适配器密封件可滑动地与轨道接合。适配器密封件包括容纳具有用于接收外科器械的孔的密封元件的板。适配器密封件具有用于将适配器密封件保持在轨道中的接合装置。此外，适配器密封件具有释放装置，其可以被作用于对张紧装置施加抵抗力，以便从套管组件移除适配器密封件。

4. 发明申请

US20070198046A1 Surgical visualization tool 审中-公开
标题翻译：手术可视化工具
公开(公告)号：US20070198046A1
公开(公告)日：2007-08-23
申请号：US11356581
申请日：2006-02-17
申请人： Edwin Hlavka , Gregory Brucker , Steven Savage , Adam Berman
发明人： Edwin Hlavka , Gregory Brucker , Steven Savage , Adam Berman
IPC分类号： A61M29/00
CPC分类号： A61B1/00165 , A61B1/00082 , A61B1/018 , A61B1/3132
摘要： The tool for enhancing visualization during surgery includes a shaft having a balloon member at a distal end. A fluid conduit through the shaft permits passing and inflation fluid into the balloon to selectively inflate the balloon. The balloon is formed of a material transparent to a wavelength of interest. A waveguide extends within the shaft into the interior of the balloon to visualize anatomical features external to the balloon.
摘要翻译：用于在手术期间增强可视化的工具包括在远端具有气囊构件的轴。通过轴的流体导管允许通过和充气流体进入球囊以选择性地使球囊膨胀。气球由对感兴趣的波长透明的材料形成。波导在轴内延伸到气囊的内部，以可视化气球外部的解剖特征。

5. 发明申请

US20060057560A1 System and method for denaturing and fixing collagenous tissue 有权
公开(公告)号：US20060057560A1
公开(公告)日：2006-03-16
申请号：US11185432
申请日：2005-07-19
申请人： Edwin Hlavka , Frederic Moll , Robert Younge , Daniel Wallace
发明人： Edwin Hlavka , Frederic Moll , Robert Younge , Daniel Wallace
IPC分类号： A61B17/00 , C12Q1/00
CPC分类号： A61B18/1492 , A61B17/00234 , A61B17/3478 , A61B18/1477 , A61B34/20 , A61B34/25 , A61B34/30 , A61B34/37 , A61B34/71 , A61B34/76 , A61B2017/00199 , A61B2017/00243 , A61B2018/1425 , A61B2034/102 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/301 , A61B2034/715 , A61B2034/742 , A61B2090/065 , A61B2090/378
摘要： A method for modifying a geometry of a collagenous tissue mass includes heating the collagenous tissue mass to a temperature sufficient to cause denaturation, and introducing a biocompatible fixative, such as genepin, into the collagenous tissue mass.

6. 发明申请

US20050247558A1 Electrokinetic delivery systems, devices and methods 有权
标题翻译：电动输送系统，装置和方法
公开(公告)号：US20050247558A1
公开(公告)日：2005-11-10
申请号：US11112867
申请日：2005-04-21
申请人： Deon Anex , Phillip Paul , David Neyer , Edwin Hlavka
发明人： Deon Anex , Phillip Paul , David Neyer , Edwin Hlavka
IPC分类号： A61M5/142 , A61M5/145 , A61M5/148 , A61M5/172 , B67D99/00 , F04B19/00 , F04B43/04 , B67D5/00
CPC分类号： A61M5/14276 , A61M5/14248 , A61M5/1483 , A61M5/1723 , A61M2005/14513 , A61M2205/52 , A61M2230/201 , F04B19/006 , F04B43/043 , Y10T137/0318 , Y10T137/0357 , Y10T137/0368 , Y10T137/0379 , Y10T137/218
摘要： A method of pumping fluid including the steps of providing an electrokinetic pump comprising a pair of double-layer capacitive electrodes having a capacitance of at least 10−2 Farads/cm2 and being connectable to a power source, a porous dielectric material disposed between the electrodes and a reservoir containing pump fluid; connecting the electrodes to a power source; and moving pump fluid out of the reservoir substantially without the occurrence of Faradaic processes in the pump. The invention also includes an electrokinetic pump system having a pair of double-layer capacitive electrodes having a capacitance of at least 10−2 Farads/cm2; a porous dielectric material disposed between the electrodes; a reservoir containing pump fluid; and a power source connected to the electrodes; the electrodes, dielectric material and power source being adapted to move the pump fluid out of the reservoir substantially without the occurrence of Faradaic processes in the pump.
摘要翻译：一种泵送流体的方法，包括以下步骤：提供电动泵，其包括一对具有至少10欧/平方厘米/平方厘米的电容的双层电容电极和可连接到电源，设置在电极之间的多孔介电材料和容纳泵流体的储存器; 将电极连接到电源; 并将泵流体从储存器中移出基本上不会在泵中发生法拉第过程。本发明还包括具有一对双电容电极的电动泵系统，电容器具有至少10欧/平方英尺/平方厘米的电容; 设置在电极之间的多孔电介质材料; 包含泵液的储存器; 以及连接到所述电极的电源; 电极，电介质材料和电源适于将泵流体基本上移出储存器，而不会在泵中发生法拉第过程。

7. 发明申请

US20050184122A1 Method and apparatus for performing catheter-based annuloplasty using local plications 审中-公开
标题翻译：使用局部麻醉进行基于导管的瓣膜成形术的方法和装置
公开(公告)号：US20050184122A1
公开(公告)日：2005-08-25
申请号：US11111044
申请日：2005-04-21
申请人： Edwin Hlavka , Paul Spence
发明人： Edwin Hlavka , Paul Spence
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61B17/068 , A61B19/00 , A61F2/24 , A61M20060101
CPC分类号： A61B17/00234 , A61B17/0469 , A61B17/0487 , A61B17/0643 , A61B17/0644 , A61B2017/00243 , A61B2017/00349 , A61B2017/00867 , A61B2017/0417 , A61B2017/0462 , A61B2017/0464 , A61B2017/0472 , A61B2017/0496 , A61B2017/0649
摘要： A minimally invasive method of performing annuloplasty. According to one aspect, a method for performing annuloplasty includes creating a first plication in the tissue near a mitral valve of a heart, using at least a first plication element, and creating a second plication in the tissue near the mitral valve such that the second plication is substantially coupled to the first plication.
摘要翻译：进行瓣膜成形术的微创方法。根据一个方面，一种用于进行瓣膜成形术的方法包括使用至少第一pl裂元件在心脏的二尖瓣附近的组织中产生第一脓肿，并在二尖瓣附近的组织中产生第二脓肿，使得第二折叠基本上与第一塌陷相耦合。

8. 发明申请

US20060095059A1 Devices and methods for tissue modification 有权
公开(公告)号：US20060095059A1
公开(公告)日：2006-05-04
申请号：US11251199
申请日：2005-10-15
申请人： Jeffery Bleich , Edwin Hlavka , Vahid Saadat , Steven Spisak , David Miller , James Yurchenco
发明人： Jeffery Bleich , Edwin Hlavka , Vahid Saadat , Steven Spisak , David Miller , James Yurchenco
IPC分类号： A61B17/32
CPC分类号： A61B17/320758 , A61B1/3135 , A61B17/149 , A61B17/1659 , A61B17/1671 , A61B17/29 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3496 , A61B18/1477 , A61B18/1487 , A61B90/04 , A61B90/361 , A61B2017/00261 , A61B2017/00287 , A61B2017/003 , A61B2017/00867 , A61B2017/00907 , A61B2017/320004 , A61B2017/320044 , A61B2017/32006 , A61B2017/3445 , A61B2017/3447 , A61B2018/1407 , A61B2018/1425 , A61B2090/061 , A61B2090/08021 , A61F2/0045 , A61N1/0551 , A61N1/36017
摘要： Methods and apparatus are provided for selective surgical removal of tissue, e.g., for enlargement of diseased spinal structures, such as impinged lateral recesses and pathologically narrowed neural foramen. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. Once the sharp tip of the needle is in the epidural space, it is converted to a blunt tipped instrument for further safe advancement. A specially designed epidural catheter that is used to cover the previously sharp needle tip may also contain a fiberoptic cable. Further embodiments of the current invention include a double barreled epidural needle or other means for placement of a working channel for the placement of tools within the epidural space, beside the epidural instrument. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. In one variation, a tissue abrasion device is provided including a thin belt or ribbon with an abrasive cutting surface. The device may be placed through the neural foramina of the spine and around the anterior border of a facet joint. Once properly positioned, a medical practitioner may enlarge the lateral recess and neural foramina via frictional abrasion, i.e., by sliding the abrasive surface of the ribbon across impinging tissues. A nerve stimulator optionally may be provided to reduce a risk of inadvertent neural abrasion. Additionally, safe epidural placement of the working barrier and epidural tissue modification tools may be further improved with the use of electrical nerve stimulation capabilities within the invention that, when combined with neural stimulation monitors, provide neural localization capabilities to the surgeon. The device optionally may be placed within a protective sheath that exposes the abrasive surface of the ribbon only in the area where tissue removal is desired. Furthermore, an endoscope may be incorporated into the device in order to monitor safe tissue removal. Finally, tissue remodeling within the epidural space may be ensured through the placement of compression dressings against remodeled tissue surfaces, or through the placement of tissue retention straps, belts or cables that are wrapped around and pull under tension aspects of the impinging soft tissue and bone in the posterior spinal canal.

9. 发明申请

US20060089640A1 Devices and methods for tissue modification 有权
公开(公告)号：US20060089640A1
公开(公告)日：2006-04-27
申请号：US11251204
申请日：2005-10-15
申请人： Jeffery Bleich , Edwin Hlavka
发明人： Jeffery Bleich , Edwin Hlavka
IPC分类号： A61B18/18
CPC分类号： A61B17/320758 , A61B17/149 , A61B17/1659 , A61B17/1671 , A61B17/29 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3496 , A61B18/1477 , A61B18/1487 , A61B90/04 , A61B2017/00261 , A61B2017/00287 , A61B2017/003 , A61B2017/00867 , A61B2017/320004 , A61B2017/320044 , A61B2017/32006 , A61B2017/3445 , A61B2017/3447 , A61B2018/1407 , A61B2018/1425 , A61B2090/061 , A61B2090/08021 , A61F2/0045 , A61N1/0551 , A61N1/36017
摘要： Methods and apparatus are provided for selective surgical removal of tissue. In one variation, tissue may be ablated, resected, removed, or otherwise remodeled by standard small endoscopic tools delivered into the epidural space through an epidural needle. The sharp tip of the needle in the epidural space, can be converted to a blunt tipped instrument for further safe advancement. The current invention includes specific tools that enable safe tissue modification in the epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. A nerve stimulator may be provided to reduce a risk of inadvertent neural abrasion.

10. 发明授权

US08202315B2 Catheter-based annuloplasty using ventricularly positioned catheter 有权
标题翻译：基于导管的瓣膜成形术使用心室定位导管
公开(公告)号：US08202315B2
公开(公告)日：2012-06-19
申请号：US12848995
申请日：2010-08-02
申请人： Edwin Hlavka , Jonathan Podmore , Paul A. Spence
发明人： Edwin Hlavka , Jonathan Podmore , Paul A. Spence
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B17/0487 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/08 , A61B17/083 , A61B2017/00004 , A61B2017/00243 , A61B2017/00783 , A61B2017/00867 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0472 , A61B2017/048 , A61B2017/0488 , A61B2017/0496 , A61B2017/081 , A61F2/2442 , A61F2/2448 , A61F2/246 , A61F2/2466
摘要： The present invention relates to a minimally invasive method of performing annuloplasty. According to one aspect of the present invention, a method for performing annuloplasty includes accessing a left ventricle of a heart to provide a discrete plication element to the left ventricle, and engaging the plication element to tissue near a mitral valve of the heart. Engaging the plication element includes causing the plication element to gather a portion of the tissue to create a plication. In one embodiment, accessing the left ventricle of the heart to provide the plication element includes accessing the left ventricle of the heart using a catheter arrangement.
摘要翻译：本发明涉及执行瓣环成形术的微创方法。根据本发明的一个方面，一种用于进行瓣膜成形术的方法包括进入心脏的左心室以向左心室提供离散的折叠元件，并且将折叠元件接合到心脏二尖瓣附近的组织。使折叠元件接合包括使折叠元件收集组织的一部分以产生折痕。在一个实施例中，进入心脏的左心室以提供脓肿元件包括使用导管装置进入心脏的左心室。

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