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1. 发明申请

US20110009801A1 DEVICES AND METHODS FOR TREATMENT OF OBESITY 有权
标题翻译：用于治疗肥胖的装置和方法
公开(公告)号：US20110009801A1
公开(公告)日：2011-01-13
申请号：US12677227
申请日：2008-09-12
申请人： David Blaeser , Dale Spencer
发明人： David Blaeser , Dale Spencer
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61B17/064 , A61B17/0644 , A61B2017/00818 , A61F2/04 , A61F2002/045
摘要： A device for isolating tissue in the digestive tract including a biocompatible portion having a surface sized to cover the tissue to be isolated and also includes a plurality of micro-anchors attached to the biocompatible portion and extending from the surface, the micro-anchors sized to penetrate the mucosa of the tissue. A method for isolating tissue in the digestive tract in which an isolation element is delivered to a desired location in the digestive system; the isolation element having fixed thereto a plurality of micro-anchors. The method also includes attaching the isolation element to tissue at the desired location by causing the micro-anchors to penetrate the mucosa of the tissue.
摘要翻译：一种用于分离消化道中的组织的装置，包括生物相容部分，其具有尺寸适于覆盖要分离的组织的表面，并且还包括附接到生物相容部分并从表面延伸的多个微锚，所述微锚尺寸为穿透组织的粘膜。一种用于分离消化道中的组织的方法，其中分离元件被递送到消化系统中的期望位置; 该隔离元件固定有多个微锚。该方法还包括通过使微锚定体穿透组织的粘膜而将隔离元件附接到期望位置处的组织。

2. 发明申请

US20060036284A1 PFO closure devices and related methods of use 有权
公开(公告)号：US20060036284A1
公开(公告)日：2006-02-16
申请号：US11249317
申请日：2005-10-14
申请人： David Blaeser , Peter Keith , Jerome Grudem , Scott Olson , Steven Hackett , Thomas Ressemann , Joel Phillips , Mark Christianson , Dennis Wahr
发明人： David Blaeser , Peter Keith , Jerome Grudem , Scott Olson , Steven Hackett , Thomas Ressemann , Joel Phillips , Mark Christianson , Dennis Wahr
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/00491 , A61B17/0057 , A61B17/0401 , A61B2017/00575 , A61B2017/00592 , A61B2017/00615 , A61B2017/0409 , A61B2017/0458 , A61B2017/0464 , A61B2017/0474 , A61B2017/0496 , A61B2017/22051
摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

3. 发明申请

US20050131447A1 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US20050131447A1
公开(公告)日：2005-06-16
申请号：US11034824
申请日：2005-01-14
申请人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
发明人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
IPC分类号： A61B17/00 , A61B17/12 , A61B17/22 , A61B19/00 , A61F2/06 , A61F2/82 , A61F2/84 , A61M25/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Prior to advancing a device across a stenosis to be treated, normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped. While blood flow is stopped, the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。抽真空组件包括限定具有近端和远端的抽空腔的细长管。近侧密封表面设置在管的近端部分上，并被构造成与引导导管的内腔形成密封。远端密封表面设置在管的远端部分上并构造成与血管形成密封。使用排气鞘组件治疗血管的方法包括通过引导导管将排空鞘组件推进到血管中。在将装置推进通过待治疗的狭窄之前，停止在狭窄附近的血管中的正常顺行血流。当血流停止时，狭窄处理。在血管内引起逆行血流，以便在处理进入抽真空鞘组件期间将栓塞物移走。

4. 发明申请

US20210196320A1 APPARATUS AND METHOD FOR SEPTAL PUNCH 有权
公开(公告)号：US20210196320A1
公开(公告)日：2021-07-01
申请号：US17192329
申请日：2021-03-04
申请人： James S. GAMMIE , Philip J. HAARSTAD , David BLAESER , Ryan BAUER , Stephen ROLLER , Rachael QUINN , Chetan PASRIJA , Edwin HLAVKA
发明人： James S. GAMMIE , Philip J. HAARSTAD , David BLAESER , Ryan BAUER , Stephen ROLLER , Rachael QUINN , Chetan PASRIJA , Edwin HLAVKA
IPC分类号： A61B17/34
摘要： In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.

5. 发明申请

US20150374524A1 DEVICES AND METHODS FOR TREATMENT OF OBESITY 审中-公开
标题翻译：用于治疗肥胖的装置和方法
公开(公告)号：US20150374524A1
公开(公告)日：2015-12-31
申请号：US14847486
申请日：2015-09-08
申请人： David Blaeser , Dale Spencer
发明人： David Blaeser , Dale Spencer
IPC分类号： A61F5/00 , A61B17/064
CPC分类号： A61F5/0076 , A61B17/064 , A61B17/0644 , A61B2017/00818 , A61F2/04 , A61F2002/045
摘要： A device for isolating tissue in the digestive tract including a biocompatible portion having a surface sized to cover the tissue to be isolated and also includes a plurality of micro-anchors attached to the biocompatible portion and extending from the surface, the micro-anchors sized to penetrate the mucosa of the tissue. A method for isolating tissue in the digestive tract in which an isolation element is delivered to a desired location in the digestive system; the isolation element having fixed thereto a plurality of micro-anchors. The method also includes attaching the isolation element to tissue at the desired location by causing the micro-anchors to penetrate the mucosa of the tissue.
摘要翻译：一种用于分离消化道中的组织的装置，包括生物相容部分，其具有尺寸适于覆盖要分离的组织的表面，并且还包括附接到生物相容部分并从表面延伸的多个微锚，所述微锚尺寸为穿透组织的粘膜。一种用于分离消化道中的组织的方法，其中分离元件被递送到消化系统中的期望位置; 该隔离元件固定有多个微锚。该方法还包括通过使微锚定体穿透组织的粘膜而将隔离元件附接到期望位置处的组织。

6. 发明授权

US09155608B2 Devices and methods for treatment of obesity 有权
标题翻译：用于治疗肥胖的装置和方法
公开(公告)号：US09155608B2
公开(公告)日：2015-10-13
申请号：US12677227
申请日：2008-09-12
申请人： David Blaeser , Dale Spencer
发明人： David Blaeser , Dale Spencer
IPC分类号： A61F2/04 , A61B19/00 , A61F2/36 , A61B17/064 , A61F5/00 , A61B17/00
CPC分类号： A61F5/0076 , A61B17/064 , A61B17/0644 , A61B2017/00818 , A61F2/04 , A61F2002/045
摘要： A device for isolating tissue in the digestive tract including a biocompatible portion having a surface sized to cover the tissue to be isolated and also includes a plurality of micro-anchors attached to the biocompatible portion and extending from the surface, the micro-anchors sized to penetrate the mucosa of the tissue. A method for isolating tissue in the digestive tract in which an isolation element is delivered to a desired location in the digestive system; the isolation element having fixed thereto a plurality of micro-anchors. The method also includes attaching the isolation element to tissue at the desired location by causing the micro-anchors to penetrate the mucosa of the tissue.
摘要翻译：一种用于分离消化道中的组织的装置，包括生物相容部分，其具有尺寸适于覆盖要分离的组织的表面，并且还包括附接到生物相容部分并从表面延伸的多个微锚，所述微锚尺寸为穿透组织的粘膜。一种用于分离消化道中的组织的方法，其中分离元件被递送到消化系统中的期望位置; 该隔离元件固定有多个微锚。该方法还包括通过使微锚定体穿透组织的粘膜而将隔离元件附接到期望位置处的组织。

7. 发明申请

US20070016250A1 Closure devices, related delivery methods, and related methods of use 有权
标题翻译：关闭装置，相关的运送方式和相关的使用方法
公开(公告)号：US20070016250A1
公开(公告)日：2007-01-18
申请号：US11522158
申请日：2006-09-16
申请人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
发明人： David Blaeser , Jerome Grudem , Scott Olson , Mark Christianson , Scott Hanson , Edward Anderson , Patrick Russo , Dennis Wahr
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor preferably also includes a plurality of arms and preferably, does not include a cover. Preferably, the elongate member has a first end fixedly connected to the left atrial anchor and a portion, proximal to the first end, passing through the right atrial anchor. Preferably, the elongate member is flexible.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚右心房锚优选地包括多个臂和附接到臂的盖。左心房锚优选地还包括多个臂，优选地不包括盖。优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的部分，穿过右心房锚。优选地，细长构件是柔性的。

8. 发明申请

US20060116659A1 Emboli protection device and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US20060116659A1
公开(公告)日：2006-06-01
申请号：US11337126
申请日：2006-01-19
申请人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
发明人： Dennis Wahr , Thomas Ressemann , Peter Keith , David Blaeser , Michael Berman
IPC分类号： A61M31/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a lesion within a blood vessel, e.g., a coronary artery, includes advancing a sheath into the blood vessel, the sheath having a lumen extending to a port at a distal end of the sheath and further having an occlusive member within a distal region of the sheath. The occlusive member is then positioned within the blood vessel proximal to the lesion. Subsequently, the occlusive member is deployed, thereby stopping antegrade flow across the lesion. A contrast agent can then be infused through a port in the sheath. A dilation balloon is then advanced across the lesion. Suction is then applied to the lumen to induce retrograde flow across the lesion after dilating the lesion.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。治疗血管（例如冠状动脉）内的病变的方法包括使鞘进入血管，护套具有延伸到护套远端端口处的内腔，并且还具有闭塞构件护套的远端区域。然后将闭塞性构件定位在靠近病变的血管内。随后，闭塞成员被部署，从而阻止穿过病变的顺行流动。然后可以通过护套中的端口注入造影剂。然后将扩张气囊推进穿过病变。然后在扩张病变之后，将吸引应用于管腔以诱导穿过病变的逆行流。

9. 发明申请

US20050267526A1 Closure devices, related delivery methods and tools, and related methods of use 审中-公开
标题翻译：关闭装置，相关的运送方式和工具以及相关的使用方法
公开(公告)号：US20050267526A1
公开(公告)日：2005-12-01
申请号：US11185951
申请日：2005-07-21
申请人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
发明人： Dennis Wahr , David Blaeser , Peter Keith , Thomas Ressemann
IPC分类号： A61B17/00 , A61B17/12 , A61B18/14 , A61M25/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2018/00214 , A61B2018/00273 , A61B2018/00351
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor also includes a plurality of arms and preferably does not include a cover. Preferably, the elongate member has a first end of fixedly connected to the left atrial anchor and a portion, proximal to the first end, releasably connected to the right atrial anchor.
摘要翻译：提供了一种用于密封心脏中卵圆孔（PFO）的装置。该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚右心房锚优选地包括多个臂和附接到臂的盖。左心房锚还包括多个臂，优选地不包括盖。优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的可释放地连接到右心房锚的部分。

10. 发明授权

US5549553A Dilation ballon for a single operator exchange intravascular catheter or similar device 失效
标题翻译：用于单个操作者的透气气囊交换血管内导管或类似装置
公开(公告)号：US5549553A
公开(公告)日：1996-08-27
申请号：US567810
申请日：1995-12-06
申请人： Thomas V. Ressemann , Timothy Stivland , David Blaeser
发明人： Thomas V. Ressemann , Timothy Stivland , David Blaeser
IPC分类号： A61F2/958 , A61M25/09 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61M25/1002 , A61M2025/0025 , A61M2025/0047 , A61M2025/0183
摘要： A dilation balloon is provided for an intravascular catheter having an elongated shaft with a proximal portion, a distal portion, and an inflation lumen extending therethrough. In one aspect of the invention, the dilation balloon includes a balloon member having a chamber therein in fluid communication with the inflation lumen. The balloon member defines a portion of a guide wire lumen which coextends with a portion of the balloon member for receiving a guide wire. In another aspect of the invention, a balloon is connected to the distal portion of the catheter shaft and a guide wire lumen is spaced exteriorly from the shaft and coextends with a portion of the balloon. In yet another aspect of the invention, a process for making a dilation balloon includes the step of providing a longitudinal member having a first elongated lumen and a second elongated lumen. A first portion of the longitudinal member which defines the first lumen is blow molded into an inflatable balloon which defines an interior chamber for receiving inflation fluid. A second portion of the longitudinal member which defines the second lumen is blow molded into a longitudinal rib which defines a guide wire lumen coextending with said chamber.
摘要翻译：提供了一种用于血管内导管的扩张气囊，其具有细长轴，其具有近端部分，远端部分和从其延伸穿过的充气腔。在本发明的一个方面，扩张气囊包括气囊构件，其中腔室与膨胀腔流体连通。气囊构件限定导丝管腔的一部分，其与球囊构件的一部分共同延伸以用于接收导丝。在本发明的另一方面，气囊连接到导管轴的远端部分，并且导丝管腔与轴隔开并与气囊的一部分共同延伸。在本发明的另一方面，一种制造膨胀气囊的方法包括提供具有第一细长内腔和第二细长内腔的纵向构件的步骤。限定第一内腔的纵向构件的第一部分被吹塑成可充气气囊，其限定用于接收充气流体的内部室。限定第二内腔的纵向构件的第二部分被吹塑成纵向肋，该纵向肋限定与所述腔共同延伸的导丝管腔。

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