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1. 发明授权

US07908007B2 System and method for detection enhancement programming 有权
公开(公告)号：US07908007B2
公开(公告)日：2011-03-15
申请号：US12566284
申请日：2009-09-24
申请人： James O. Gilkerson , Vickie L. Conley , Scott R. Stubbs , Douglas J. Lang
发明人： James O. Gilkerson , Vickie L. Conley , Scott R. Stubbs , Douglas J. Lang
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/3622 , A61N1/37 , A61N1/3962 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： A system and method of enabling detection enhancements selected from a plurality of detection enhancements. In a system having a plurality of clinical rhythms, including a first clinical rhythm, where each of the detection enhancements is associated with the clinical rhythms, the first clinical rhythm is selected. The first clinical rhythm is associated with first and second detection enhancements. When the first clinical rhythm is selected, parameters of the first and second detection enhancements are set automatically. A determination is made as to whether changes are to be made to the parameters. If so, one or more of the parameters are modified under user control.

2. 发明授权

US08855766B2 System and method for detection enhancement programming 有权
标题翻译：用于检测增强编程的系统和方法
公开(公告)号：US08855766B2
公开(公告)日：2014-10-07
申请号：US13286408
申请日：2011-11-01
申请人： James O. Gilkerson , Vickie L. Conley , Scott R. Stubbs , Douglas J. Lang
发明人： James O. Gilkerson , Vickie L. Conley , Scott R. Stubbs , Douglas J. Lang
IPC分类号： A61N1/37 , A61N1/372 , A61N1/39
CPC分类号： A61N1/3987 , A61N1/37247 , A61N1/37252 , A61N1/3925
摘要： A system and method of enabling detection enhancements selected from a plurality of detection enhancements. In a system having a plurality of clinical rhythms, including a first clinical rhythm, where each of the detection enhancements is associated with the clinical rhythms, the first clinical rhythm is selected. The first clinical rhythm is associated with first and second detection enhancements. When the first clinical rhythm is selected, parameters of the first and second detection enhancements are set automatically. A determination is made as to whether changes are to be made to the parameters. If so, one or more of the parameters are modified under user control.
摘要翻译：一种启用从多个检测增强中选择的检测增强的系统和方法。在具有多个临床节律的系统中，包括第一临床节律，其中每个检测增强与临床节律相关联，选择第一临床节律。第一种临床节律与第一和第二检测增强有关。当选择第一临床节律时，自动设置第一和第二检测增强的参数。确定是否对参数进行改变。如果是这样，则在用户控制下修改一个或多个参数。

3. 发明授权

US08639331B2 Systems and methods for providing arrhythmia therapy in MRI environments 有权
标题翻译：在MRI环境中提供心律失常治疗的系统和方法
公开(公告)号：US08639331B2
公开(公告)日：2014-01-28
申请号：US12639848
申请日：2009-12-16
申请人： Scott R. Stubbs , James O. Gilkerson , Diane Schuster
发明人： Scott R. Stubbs , James O. Gilkerson , Diane Schuster
IPC分类号： A61N1/00
CPC分类号： A61N1/3931 , A61N1/3688 , A61N1/37 , A61N1/3718
摘要： Systems and methods for arrhythmia therapy in MRI environments are disclosed. Various systems disclosed utilize ATP therapy rather than ventricular shocks when patients are subjected to electromagnetic fields in an MRI scanner bore and shock therapy is not available. As the patient is moved out from within the scanner bore and away from the MRI scanner, the magnetic fields diminish in strength eventually allowing a high voltage capacitor within the IMD to charge if necessary. The system may detect when the electromagnetic fields no longer interfere with the shock therapy and will transition the IMD back to a normal operational mode where shock therapy can be delivered. Then, if the arrhythmia still exists, the system will carry out all of the system's prescribed operations, including the delivery of electric shocks to treat the arrhythmia.
摘要翻译：公开了MRI环境中心律失常治疗的系统和方法。所公开的各种系统利用ATP治疗而不是心室休克，当患者在MRI扫描器孔中经受电磁场并且不能使用休克疗法时。当患者从扫描仪孔内移出并远离MRI扫描仪时，磁场的强度减弱，最终允许IMD内的高电压电容器根据需要进行充电。该系统可以检测何时电磁场不再干扰休克疗法，并将IMD转移回正常的操作模式，其中可以进行休克疗法。那么，如果心律失常仍然存在，系统将执行系统的所有规定的操作，包括交付电击治疗心律失常。

4. 发明申请

US20100211123A1 SYSTEMS AND METHODS FOR PROVIDING ARRHYTHMIA THERAPY IN MRI ENVIRONMENTS 有权
标题翻译：在MRI环境中提供ARRHYTHMIA治疗的系统和方法
公开(公告)号：US20100211123A1
公开(公告)日：2010-08-19
申请号：US12639848
申请日：2009-12-16
申请人： Scott R. Stubbs , James O. Gilkerson , Diane Schuster
发明人： Scott R. Stubbs , James O. Gilkerson , Diane Schuster
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3931 , A61N1/3688 , A61N1/37 , A61N1/3718
摘要： Systems and methods for arrhythmia therapy in MRI environments are disclosed. Various systems disclosed utilize ATP therapy rather than ventricular shocks when patients are subjected to electromagnetic fields in an MRI scanner bore and shock therapy is not available. As the patient is moved out from within the scanner bore and away from the MRI scanner, the magnetic fields diminish in strength eventually allowing a high voltage capacitor within the IMD to charge if necessary. The system may detect when the electromagnetic fields no longer interfere with the shock therapy and will transition the IMD back to a normal operational mode where shock therapy can be delivered. Then, if the arrhythmia still exists, the system will carry out all of the system's prescribed operations, including the delivery of electric shocks to treat the arrhythmia.
摘要翻译：公开了MRI环境中心律失常治疗的系统和方法。所公开的各种系统利用ATP治疗而不是心室休克，当患者在MRI扫描器孔中经受电磁场并且不能使用休克疗法时。当患者从扫描仪孔内移出并远离MRI扫描仪时，磁场的强度减弱，最终允许IMD内的高电压电容器根据需要进行充电。该系统可以检测何时电磁场不再干扰休克疗法，并将IMD转移回正常的操作模式，其中可以进行休克疗法。那么，如果心律失常仍然存在，系统将执行系统的所有规定的操作，包括交付电击治疗心律失常。

5. 发明授权

US08565874B2 Implantable medical device with automatic tachycardia detection and control in MRI environments 有权
标题翻译：在MRI环境中具有自动心动过速检测和控制的植入式医疗设备
公开(公告)号：US08565874B2
公开(公告)日：2013-10-22
申请号：US12907517
申请日：2010-10-19
申请人： Scott R. Stubbs , James O. Gilkerson , Hiten J. Doshi , Diane Schuster
发明人： Scott R. Stubbs , James O. Gilkerson , Hiten J. Doshi , Diane Schuster
IPC分类号： A61N1/08 , A61B5/05
CPC分类号： A61N1/3962 , A61N1/056 , A61N1/086 , A61N1/37 , A61N1/3718
摘要： An implantable medical device (IMD) includes a lead having one or more sensing electrodes and one or more therapy delivery electrodes, and a sensor configured to detect the presence of static and time-varying scan fields in a magnetic resonance imaging (MRI) environment. A controller, in electrical communication with the lead and the sensor, is configured to process signals related to tachycardia events sensed via the one or more sensing electrodes and to deliver pacing and shock therapy signals via the one or more therapy delivery electrodes. The controller compares the sensed static and time-varying scan fields to static and time-varying scan field thresholds. The controller controls delivery of anti-tachycardia pacing and shock therapy signals as a function of the detected tachycardia events, the comparison of the sensed static scan field to the static scan field threshold, and the comparison of the time-varying scan fields to the time-varying scan field thresholds.
摘要翻译：可植入医疗装置（IMD）包括具有一个或多个感测电极和一个或多个治疗递送电极的引线，以及配置成检测磁共振成像（MRI）环境中静态和时变扫描场的存在的传感器。与引线和传感器电连通的控制器被配置为处理与通过一个或多个感测电极感测的心动过速相关的信号，并且经由一个或多个治疗传递电极输送起搏和休克治疗信号。控制器将感测到的静态和时变扫描场与静态和时变扫描场阈值进行比较。控制器控制作为检测到的心动过速事件的函数的抗心动过速起搏和休克治疗信号的传递，感测的静态扫描场与静态扫描场阈值的比较，以及时变扫描场与时间的比较 - 扫描场阈值变化。

6. 发明申请

US20110137359A1 IMPLANTABLE MEDICAL DEVICE WITH AUTOMATIC TACHYCARDIA DETECTION AND CONTROL IN MRI ENVIRONMENTS 有权
标题翻译： MRI环境中具有自动TACHYCARDIA检测和控制的可植入医疗器械
公开(公告)号：US20110137359A1
公开(公告)日：2011-06-09
申请号：US12907517
申请日：2010-10-19
申请人： Scott R. Stubbs , James O. Gilkerson , Hiten J. Doshi , Diane Schuster
发明人： Scott R. Stubbs , James O. Gilkerson , Hiten J. Doshi , Diane Schuster
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/056 , A61N1/086 , A61N1/37 , A61N1/3718
摘要： An implantable medical device (IMD) includes a lead having one or more sensing electrodes and one or more therapy delivery electrodes, and a sensor configured to detect the presence of static and time-varying scan fields in a magnetic resonance imaging (MRI) environment. A controller, in electrical communication with the lead and the sensor, is configured to process signals related to tachycardia events sensed via the one or more sensing electrodes and to deliver pacing and shock therapy signals via the one or more therapy delivery electrodes. The controller compares the sensed static and time-varying scan fields to static and time-varying scan field thresholds. The controller controls delivery of anti-tachycardia pacing and shock therapy signals as a function of the detected tachycardia events, the comparison of the sensed static scan field to the static scan field threshold, and the comparison of the time-varying scan fields to the time-varying scan field thresholds.
摘要翻译：可植入医疗装置（IMD）包括具有一个或多个感测电极和一个或多个治疗递送电极的引线，以及配置成检测磁共振成像（MRI）环境中静态和时变扫描场的存在的传感器。与引线和传感器电连通的控制器被配置为处理与通过一个或多个感测电极感测的心动过速相关的信号，并且经由一个或多个治疗传递电极输送起搏和休克治疗信号。控制器将感测到的静态和时变扫描场与静态和时变扫描场阈值进行比较。控制器控制作为检测到的心动过速事件的函数的抗心动过速起搏和休克治疗信号的传递，感测的静态扫描场与静态扫描场阈值的比较，以及时变扫描场与时间的比较 - 扫描场阈值变化。

7. 发明授权

US08649862B2 Therapy circuit protection for implantable medical device 有权
标题翻译：可植入医疗器械的治疗电路保护
公开(公告)号：US08649862B2
公开(公告)日：2014-02-11
申请号：US13166297
申请日：2011-06-22
申请人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
发明人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/025 , A61N1/3706 , A61N1/3937 , A61N1/3962 , A61N2001/083
摘要： A medical device can include a therapy circuit configured to provide a specified electrostimulation therapy to a tissue site, the specified electrostimulation therapy including a scheduled completion, the therapy circuit including a protection circuit configured to adjust specification of the electrostimulation therapy being provided so as to provide an adjusted electrostimulation therapy before the scheduled completion. The medical device can include a monitoring circuit comprising a comparator. The monitoring circuit can be configured to trigger the protection circuit to inhibit the therapy circuit when the therapy circuit output parameter exceeds the specified threshold as indicated by the comparator.
摘要翻译：医疗设备可以包括治疗电路，其被配置为向组织部位提供特定的电刺激治疗，所述指定的电刺激治疗包括计划完成，所述治疗电路包括保护电路，该保护电路被配置为调整提供的电刺激治疗的规格，在计划完成之前进行调整的电刺激治疗。医疗装置可以包括包括比较器的监视电路。当比较器所指示的治疗电路输出参数超过指定的阈值时，监视电路可被配置为触发保护电路来抑制治疗电路。

8. 发明授权

US08306630B2 Apparatus to selectively increase medical device lead inner conductor inductance 有权
标题翻译：用于选择性地增加医疗器件引线内部导体电感的装置
公开(公告)号：US08306630B2
公开(公告)日：2012-11-06
申请号：US12905336
申请日：2010-10-15
申请人： Scott R. Stubbs , Jeffrey E. Stahmann , Arthur J. Foster , Ronald W. Kunkel
发明人： Scott R. Stubbs , Jeffrey E. Stahmann , Arthur J. Foster , Ronald W. Kunkel
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/086
摘要： A medical device lead includes an insulative lead body, outer and inner conductive coils, and a flexible core assembly. The outer conductive coil extends through the lead body and is coupled to a first electrode at a distal end of the outer conductive coil. The inner conductive coil extends coaxially with the outer conductive coil, is coupled to a second electrode at a distal end of the inner conductive coil, and includes a central lumen. The flexible core assembly is disposed in the central lumen and is comprised of a material that has a saturation magnetization of at least about 1.5 T and a relative permeability of greater than one. The flexible core assembly includes a positioning interface configured for manipulation of the flexible core assembly such that the flexible core assembly translates through the central lumen during insertion and extraction of the flexible core assembly.
摘要翻译：医疗器械引线包括绝缘引线体，外部和内部导电线圈以及柔性芯组件。外部导电线圈延伸穿过引线体并且在外部导电线圈的远端处耦合到第一电极。与外部导电线圈同轴地延伸的内部导电线圈耦合到内部导电线圈的远端处的第二电极，并且包括中心腔。柔性芯组件设置在中心腔中，并且由具有至少约1.5T的饱和磁化强度和大于1的相对磁导率的材料构成。柔性芯组件包括配置用于操纵柔性芯组件的定位接口，使得柔性芯组件在插入和拔出柔性芯组件期间通过中心腔平移。

9. 发明申请

US20120004694A1 THERAPY CIRCUIT PROTECTION FOR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：可植入医疗器械的治疗电路保护
公开(公告)号：US20120004694A1
公开(公告)日：2012-01-05
申请号：US13166297
申请日：2011-06-22
申请人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
发明人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/025 , A61N1/3706 , A61N1/3937 , A61N1/3962 , A61N2001/083
摘要： A medical device can include a therapy circuit configured to provide a specified electrostimulation therapy to a tissue site, the specified electrostimulation therapy including a scheduled completion, the therapy circuit including a protection circuit configured to adjust specification of the electrostimulation therapy being provided so as to provide an adjusted electrostimulation therapy before the scheduled completion. The medical device can include a monitoring circuit comprising a comparator. The monitoring circuit can be configured to trigger the protection circuit to inhibit the therapy circuit when the therapy circuit output parameter exceeds the specified threshold as indicated by the comparator.
摘要翻译：医疗设备可以包括治疗电路，其被配置为向组织部位提供特定的电刺激治疗，所述指定的电刺激治疗包括计划完成，所述治疗电路包括保护电路，该保护电路被配置为调整提供的电刺激治疗的规格，在计划完成之前进行调整的电刺激治疗。医疗装置可以包括包括比较器的监视电路。当比较器所指示的治疗电路输出参数超过指定的阈值时，监视电路可被配置为触发保护电路来抑制治疗电路。

10. 发明申请

US20110166449A1 METHOD AND APPARATUS FOR RADIATION EFFECTS DETECTION 失效
标题翻译：辐射效应检测方法与装置
公开(公告)号：US20110166449A1
公开(公告)日：2011-07-07
申请号：US13044003
申请日：2011-03-09
申请人： Jeffrey E. Stahmann , William J. Linder , Scott R. Stubbs , Keith R. Maile
发明人： Jeffrey E. Stahmann , William J. Linder , Scott R. Stubbs , Keith R. Maile
IPC分类号： A61B6/00
CPC分类号： A61N1/37 , A61N1/3718
摘要： An implantable medical apparatus comprises a solid state electronic circuit, an ionizing radiation exposure sensor, an ionizing radiation dose rate sensor, and a controller circuit. The ionizing radiation exposure sensor is configured to detect an exposure of the solid state electronic circuit to ionizing radiation, and generate an indication of a non-single-event-upset (non-SEU) effect to the solid state electronic circuit from the exposure to ionizing radiation, wherein the sensor comprises an accumulated ionizing radiation exposure sensor. The controller circuit is configured to blank the indication from the accumulated ionizing radiation exposure sensor when the radiation dose rate sensor indicates that flux ionizing radiation exceeds a flux ionizing radiation threshold.
摘要翻译：一种可植入医疗装置，包括固态电子电路，电离辐射曝光传感器，电离辐射剂量率传感器和控制器电路。电离辐射曝光传感器被配置为检测固态电子电路对电离辐射的曝光，并且产生对固态电子电路的非单事件不适（非SEU）效应的指示，从曝光到电离辐射，其中所述传感器包括累积的电离辐射曝光传感器。控制器电路被配置为当辐射剂量率传感器指示通量电离辐射超过通量电离辐射阈值时，从累积的电离辐射曝光传感器中消除指示。

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