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1. 发明申请

US20100185132A1 ACCESS DISCONNECTION SYSTEMS AND METHODS USING CONDUCTIVE CONTACTS 有权
标题翻译：访问断开系统和使用导电触点的方法
公开(公告)号：US20100185132A1
公开(公告)日：2010-07-22
申请号：US12727993
申请日：2010-03-19
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M1/36
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood system includes: an extracorporeal blood machine including an extracorporeal blood circuit; an access device enabling the extracorporeal blood circuit to be connected to a patient; first and second tube connecting members for connecting respectively to first and second tubes of the extracorporeal circuit; first and second electrodes held, at least in part, by the first and second tube connecting members so as to contact blood flowing through the extracorporeal blood circuit, the first and second electrodes enabling an electrical signal to be injected into the extracorporeal blood circuit; first and second contact members contacting the first and second electrodes respectively; and electronics coupled operably to the first and second contact members for applying the electrical signal, the signal used to monitor the access device.
摘要翻译：体外血液系统包括：体外血液机器，包括体外血液回路; 允许体外血液回路连接到患者的进入装置; 第一和第二管连接构件，用于分别连接到体外回路的第一和第二管; 第一和第二电极至少部分地由第一和第二管连接构件保持以接触流过体外血液回路的血液，第一和第二电极能够将电信号注射到体外血液回路中; 分别与第一和第二电极接触的第一和第二接触构件; 以及可操作地耦合到第一和第二接触构件的电子装置，用于施加电信号，用于监测接入装置的信号。

2. 发明授权

US07052480B2 Access disconnection systems and methods 有权
标题翻译：访问断开连接系统和方法
公开(公告)号：US07052480B2
公开(公告)日：2006-05-30
申请号：US10120684
申请日：2002-04-10
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M37/00 , B01D11/00 , C02F1/00 , A61B5/00
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： Apparatuses, devices, systems and methods for detecting access disconnection during medical therapy are provided. The present invention includes an electric circuit coupled to, for example, a blood circuit used during dialysis therapy. The electric circuit can inject an electrical signal into the blood circuit such that changes in an electrical value in response to access disconnection, such as needle drop-out or catheter drop-out, can be effectively detected.
摘要翻译：提供了用于在药物治疗期间检测进入断开的装置，装置，系统和方法。本发明包括耦合到例如在透析治疗期间使用的血液回路的电路。电路可以将电信号注入到血液回路中，使得可以有效地检测出响应于诸如针脱落或导管脱出的进入断开的电值的变化。

3. 发明授权

US08708946B2 Access disconnection systems using conductive contacts 有权
标题翻译：使用导电触点访问断开系统
公开(公告)号：US08708946B2
公开(公告)日：2014-04-29
申请号：US13412249
申请日：2012-03-05
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood machine includes a blood circuit; an access device enabling the blood circuit to be connected to a patient; first and second coupling devices for connecting to first and second tubes of the circuit; first and second electrodes held by the first and second coupling devices to contact blood flowing through the blood circuit, the electrodes enabling an electrical signal to be injected into the circuit; first and second contact members contacting the first and second electrodes, wherein at least one of the coupling devices includes a stem portion enabling at least one of the first and second contact members to contact at least one of the first and second electrodes, respectively, on an outer portion of the at least one electrode without disturbing blood flowing through the coupling device; and electronics coupled operably to the first and second contact members for applying the electrical signal.
摘要翻译：体外血液机器包括血液回路; 使得血液回路连接到患者的进入装置; 用于连接到电路的第一和第二管的第一和第二耦合装置; 由第一和第二耦合装置保持的第一和第二电极，以接触流过血液回路的血液，所述电极使得电信号被注入到电路中; 第一和第二接触构件与第一和第二电极接触，其中至少一个联接装置包括杆部分，使得第一和第二接触构件中的至少一个能够分别接触第一和第二电极中的至少一个，所述至少一个电极的外部部分，而不扰动血液流过所述联接装置; 以及可操作地耦合到第一和第二接触构件的电子装置，用于施加电信号。

4. 发明申请

US20120215151A1 ACCESS DISCONNECTION SYSTEMS USING CONDUCTIVE CONTACTS 有权
标题翻译：使用导电连接的访问断开系统
公开(公告)号：US20120215151A1
公开(公告)日：2012-08-23
申请号：US13412249
申请日：2012-03-05
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M1/14
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood machine includes a blood circuit; an access device enabling the blood circuit to be connected to a patient; first and second coupling devices for connecting to first and second tubes of the circuit; first and second electrodes held by the first and second coupling devices to contact blood flowing through the blood circuit, the electrodes enabling an electrical signal to be injected into the circuit; first and second contact members contacting the first and second electrodes, wherein at least one of the coupling devices includes a stem portion enabling at least one of the first and second contact members to contact at least one of the first and second electrodes, respectively, on an outer portion of the at least one electrode without disturbing blood flowing through the coupling device; and electronics coupled operably to the first and second contact members for applying the electrical signal.
摘要翻译：体外血液机器包括血液回路; 使得血液回路连接到患者的进入装置; 用于连接到电路的第一和第二管的第一和第二耦合装置; 由第一和第二耦合装置保持的第一和第二电极，以接触流过血液回路的血液，所述电极使得电信号被注入到电路中; 第一和第二接触构件与第一和第二电极接触，其中至少一个联接装置包括杆部分，使得第一和第二接触构件中的至少一个能够分别接触第一和第二电极中的至少一个，所述至少一个电极的外部部分，而不扰动血液流过所述联接装置; 以及可操作地耦合到第一和第二接触构件的电子装置，用于施加电信号。

5. 发明授权

US08137300B2 Access disconnection systems and methods using conductive contacts 有权
标题翻译：访问断开系统和使用导电触点的方法
公开(公告)号：US08137300B2
公开(公告)日：2012-03-20
申请号：US12727993
申请日：2010-03-19
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood system includes: an extracorporeal blood machine including an extracorporeal blood circuit; an access device enabling the extracorporeal blood circuit to be connected to a patient; first and second tube connecting members for connecting respectively to first and second tubes of the extracorporeal circuit; first and second electrodes held, at least in part, by the first and second tube connecting members so as to contact blood flowing through the extracorporeal blood circuit, the first and second electrodes enabling an electrical signal to be injected into the extracorporeal blood circuit; first and second contact members contacting the first and second electrodes respectively; and electronics coupled operably to the first and second contact members for applying the electrical signal, the signal used to monitor the access device.
摘要翻译：体外血液系统包括：体外血液机器，包括体外血液回路; 允许体外血液回路连接到患者的进入装置; 第一和第二管连接构件，用于分别连接到体外回路的第一和第二管; 第一和第二电极至少部分地由第一和第二管连接构件保持以接触流过体外血液回路的血液，第一和第二电极能够将电信号注射到体外血液回路中; 分别与第一和第二电极接触的第一和第二接触构件; 以及可操作地耦合到第一和第二接触构件的电子装置，用于施加电信号，用于监测接入装置的信号。

6. 发明授权

US07682328B2 Access disconnection systems and methods 有权
标题翻译：访问断开系统和方法
公开(公告)号：US07682328B2
公开(公告)日：2010-03-23
申请号：US11331609
申请日：2006-01-16
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood system includes: (i) an extracorporeal blood machine; an extracorporeal blood circuit coupled operably to the machine, the extracorporeal blood circuit including first and second blood lines, the blood lines configured to be in blood flow communication with a patient; (ii) an electrical loop including first and second electrodes placed in contact with blood flowing through the extracorporeal blood circuit; (iii) a device configured to inject an electrical signal into the blood circuit via the loop; and (iv) a third electrode placed in contact with blood flowing through the extracorporeal blood circuit, the third electrode configured to enable a change in an electrical value to be measured so that an access disconnection of the extracorporeal blood circuit from the patient can be measured.
摘要翻译：体外血液系统包括：（i）体外血液机器; 体外血液循环，其可操作地耦合到所述机器，所述体外血液回路包括第一和第二血液线，所述血液线被配置为与患者血液流通; （ii）电回路，其包括与流过所述体外血液回路的血液接触的第一和第二电极; （iii）被配置为经由环路将电信号注入到血液回路中的装置; 以及（iv）与流过所述体外血液回路的血液接触的第三电极，所述第三电极被配置为能够测量要测量的电值的变化，从而可以测量体外血液回路与患者的进入断开。

7. 发明授权

US08529490B2 Systems and methods for dialysis access disconnection 有权
标题翻译：用于透析访问断开的系统和方法
公开(公告)号：US08529490B2
公开(公告)日：2013-09-10
申请号：US13157010
申请日：2011-06-09
申请人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
发明人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/30 , A61M1/16 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M1/367 , A61M5/16831 , A61M5/5086 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50
摘要： An access disconnection method for a machine employing a blood circuit, the blood circuit having a machine segment and a patient access segment, the method comprising: injecting an electrical signal into the blood circuit between the machine segment and the patient access segment; attempting to cause the electrical signal to flow through only the patient access segment and to bypass the machine segment; and measuring the signal in the patient access segment and determining that an access disconnection event has occurred upon a threshold change in the measured signal.
摘要翻译：一种采用血液循环的机器的接入断开方法，所述血液回路具有机器段和患者接入段，所述方法包括：将电信号注入所述机器段和所述患者接入段之间的血液回路中; 试图使电信号仅流过患者接入段并绕过机器段; 以及测量患者访问段中的信号，并且在测量信号的阈值改变时确定存在接入断开事件已经发生。

8. 发明授权

US07022098B2 Access disconnection systems and methods 有权
公开(公告)号：US07022098B2
公开(公告)日：2006-04-04
申请号：US10120703
申请日：2002-04-10
申请人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
发明人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
IPC分类号： A61M37/00 , B01D11/00
CPC分类号： A61M1/30 , A61M1/16 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M1/367 , A61M5/16831 , A61M5/5086 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50
摘要： Apparatuses, devices, systems and methods for detecting access disconnection are provided. The present invention includes electrical contacts in fluid and electrical communication with a fluid passing between a patient and a medical system during therapy. In this regard, the present invention can use a direct-contact measurement to detect access disconnection, such as dislodgment of an access device from the patient through which fluid can flow during therapy including, for example, medication delivery, dialysis therapy and the like.

9. 发明申请

US20060116623A1 Access disconnection systems and methods 有权
标题翻译：访问断开系统和方法
公开(公告)号：US20060116623A1
公开(公告)日：2006-06-01
申请号：US11331609
申请日：2006-01-16
申请人： James Han , Thomas Hartranft , Thomas Kelly , Angel Lasso
发明人： James Han , Thomas Hartranft , Thomas Kelly , Angel Lasso
IPC分类号： A61M37/00
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood system includes: (i) an extracorporeal blood machine; an extracorporeal blood circuit coupled operably to the machine, the extracorporeal blood circuit including first and second blood lines, the blood lines configured to be in blood flow communication with a patient; (ii) an electrical loop including first and second electrodes placed in contact with blood flowing through the extracorporeal blood circuit; (iii) a device configured to inject an electrical signal into the blood circuit via the loop; and (iv) a third electrode placed in contact with blood flowing through the extracorporeal blood circuit, the third electrode configured to enable a change in an electrical value to be measured so that an access disconnection of the extracorporeal blood circuit from the patient can be measured.
摘要翻译：体外血液系统包括：（i）体外血液机器; 体外血液循环，其可操作地耦合到所述机器，所述体外血液回路包括第一和第二血液线，所述血液线被配置为与患者血液流通; （ii）电回路，其包括与流过所述体外血液回路的血液接触的第一和第二电极; （iii）被配置为经由环路将电信号注入到血液回路中的装置; 以及（iv）与流过所述体外血液回路的血液接触的第三电极，所述第三电极被配置为能够测量要测量的电值的变化，从而可以测量体外血液回路与患者的通路断开。

10. 发明申请

US20110237998A1 SYSTEMS AND METHODS FOR DIALYSIS ACCESS DISCONNECTION 有权
标题翻译：用于DIALYSIS ACCESS DISCONNECTION的系统和方法
公开(公告)号：US20110237998A1
公开(公告)日：2011-09-29
申请号：US13157010
申请日：2011-06-09
申请人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
发明人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
IPC分类号： A61M1/14 , G01R27/28
CPC分类号： A61M1/30 , A61M1/16 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M1/367 , A61M5/16831 , A61M5/5086 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50
摘要： An access disconnection method for a machine employing a blood circuit, the blood circuit having a machine segment and a patient access segment, the method comprising: injecting an electrical signal into the blood circuit between the machine segment and the patient access segment; attempting to cause the electrical signal to flow through only the patient access segment and to bypass the machine segment; and measuring the signal in the patient access segment and determining that an access disconnection event has occurred upon a threshold change in the measured signal.
摘要翻译：一种采用血液循环的机器的接入断开方法，所述血液回路具有机器段和患者接入段，所述方法包括：将电信号注入所述机器段和所述患者接入段之间的血液回路中; 试图使电信号仅流过患者接入段并绕过机器段; 以及测量患者访问段中的信号，并且在测量信号的阈值改变时确定存在接入断开事件已经发生。

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