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1. 发明授权

US08529490B2 Systems and methods for dialysis access disconnection 有权
标题翻译：用于透析访问断开的系统和方法
公开(公告)号：US08529490B2
公开(公告)日：2013-09-10
申请号：US13157010
申请日：2011-06-09
申请人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
发明人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/30 , A61M1/16 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M1/367 , A61M5/16831 , A61M5/5086 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50
摘要： An access disconnection method for a machine employing a blood circuit, the blood circuit having a machine segment and a patient access segment, the method comprising: injecting an electrical signal into the blood circuit between the machine segment and the patient access segment; attempting to cause the electrical signal to flow through only the patient access segment and to bypass the machine segment; and measuring the signal in the patient access segment and determining that an access disconnection event has occurred upon a threshold change in the measured signal.
摘要翻译：一种采用血液循环的机器的接入断开方法，所述血液回路具有机器段和患者接入段，所述方法包括：将电信号注入所述机器段和所述患者接入段之间的血液回路中; 试图使电信号仅流过患者接入段并绕过机器段; 以及测量患者访问段中的信号，并且在测量信号的阈值改变时确定存在接入断开事件已经发生。

2. 发明授权

US4827430A Flow measurement system 失效
标题翻译：流量测量系统
公开(公告)号：US4827430A
公开(公告)日：1989-05-02
申请号：US48307
申请日：1987-05-11
申请人： James D. Aid , Norman F. Cameron , Thomas P. Hartranft
发明人： James D. Aid , Norman F. Cameron , Thomas P. Hartranft
IPC分类号： A61M1/14 , A61M1/16 , G01F1/00 , G01F1/08 , G01F1/12 , G01F25/00 , G01F15/075 , G01P5/20
CPC分类号： G01F1/00 , A61M1/16 , A61M1/1647 , G01F1/08 , G01F1/125
摘要： A flow rate measurement system and method suitable for monitoring filtrate flow in a hemodialysis apparatus, provides a pair of flow meters in series at the input of a dialyzer for producing electrical signals indicative of dialysate flow rate and a pair of flow meters in series at the output of the dialyzer for producing electrical signals indicative of dialysate plus filtrate flow rate. A computer receives the flow rate signals and is programmed to calibrate each flow meter during a calibration phase to correct for any variations in each pair to thereby produce corrective scale factors. During an operational phase of the apparatus, the program monitors the flow meters and provides an alarm if any changes between the readings of either of the pairs of flow meters occurs.

3. 发明授权

US07022098B2 Access disconnection systems and methods 有权
公开(公告)号：US07022098B2
公开(公告)日：2006-04-04
申请号：US10120703
申请日：2002-04-10
申请人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
发明人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
IPC分类号： A61M37/00 , B01D11/00
CPC分类号： A61M1/30 , A61M1/16 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M1/367 , A61M5/16831 , A61M5/5086 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50
摘要： Apparatuses, devices, systems and methods for detecting access disconnection are provided. The present invention includes electrical contacts in fluid and electrical communication with a fluid passing between a patient and a medical system during therapy. In this regard, the present invention can use a direct-contact measurement to detect access disconnection, such as dislodgment of an access device from the patient through which fluid can flow during therapy including, for example, medication delivery, dialysis therapy and the like.

4. 发明授权

US4623328A Pump monitor for photoactivation patient treatment system 失效
标题翻译：用于光活化患者治疗系统的泵监护仪
公开(公告)号：US4623328A
公开(公告)日：1986-11-18
申请号：US665826
申请日：1984-10-29
申请人： Thomas P. Hartranft
发明人： Thomas P. Hartranft
IPC分类号： G01N33/48 , A61M1/00 , A61M1/10 , A61M1/14 , A61M1/36 , H02H7/093 , A61M1/03 , G01D5/34
CPC分类号： H02H7/093 , A61M1/3683 , A61M1/3643 , A61M1/3693 , H01H2071/006
摘要： A preferred patient blood treatment system for the photoactivation of reagents in contact with a patient's blood employs an infusion pump for adding anti-coagulation reagent to the blood during extracorporeal operations. The infusion pump is preferably driven by a stepper motor and monitored by a periodic photo chopper employing a plurality of sensors. The spacing of the sensors and the spacing of the photo choppers work in concert to detect rotation of the stepper motor and to discriminate such from stutter or other characteristic nonrotational faults associated with stepper motors.
摘要翻译：用于与患者血液接触的试剂的光活化的优选患者血液处理系统使用输液泵，用于在体外操作期间向血液中加入抗凝血试剂。输注泵优选地由步进电机驱动并由采用多个传感器的周期性光斩波器监视。传感器的间距和光斩波器的间距协调工作，以检测步进电机的旋转，并将其与步进电机相关的口吃或其他特征非旋转故障进行区分。

5. 发明申请

US20110237998A1 SYSTEMS AND METHODS FOR DIALYSIS ACCESS DISCONNECTION 有权
标题翻译：用于DIALYSIS ACCESS DISCONNECTION的系统和方法
公开(公告)号：US20110237998A1
公开(公告)日：2011-09-29
申请号：US13157010
申请日：2011-06-09
申请人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
发明人： Ramesh Wariar , James Han , George Lamberson , Thomas P. Hartranft , Thore Falkvall
IPC分类号： A61M1/14 , G01R27/28
CPC分类号： A61M1/30 , A61M1/16 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M1/367 , A61M5/16831 , A61M5/5086 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50
摘要： An access disconnection method for a machine employing a blood circuit, the blood circuit having a machine segment and a patient access segment, the method comprising: injecting an electrical signal into the blood circuit between the machine segment and the patient access segment; attempting to cause the electrical signal to flow through only the patient access segment and to bypass the machine segment; and measuring the signal in the patient access segment and determining that an access disconnection event has occurred upon a threshold change in the measured signal.
摘要翻译：一种采用血液循环的机器的接入断开方法，所述血液回路具有机器段和患者接入段，所述方法包括：将电信号注入所述机器段和所述患者接入段之间的血液回路中; 试图使电信号仅流过患者接入段并绕过机器段; 以及测量患者访问段中的信号，并且在测量信号的阈值改变时确定存在接入断开事件已经发生。

6. 发明申请

US20100185132A1 ACCESS DISCONNECTION SYSTEMS AND METHODS USING CONDUCTIVE CONTACTS 有权
标题翻译：访问断开系统和使用导电触点的方法
公开(公告)号：US20100185132A1
公开(公告)日：2010-07-22
申请号：US12727993
申请日：2010-03-19
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M1/36
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood system includes: an extracorporeal blood machine including an extracorporeal blood circuit; an access device enabling the extracorporeal blood circuit to be connected to a patient; first and second tube connecting members for connecting respectively to first and second tubes of the extracorporeal circuit; first and second electrodes held, at least in part, by the first and second tube connecting members so as to contact blood flowing through the extracorporeal blood circuit, the first and second electrodes enabling an electrical signal to be injected into the extracorporeal blood circuit; first and second contact members contacting the first and second electrodes respectively; and electronics coupled operably to the first and second contact members for applying the electrical signal, the signal used to monitor the access device.
摘要翻译：体外血液系统包括：体外血液机器，包括体外血液回路; 允许体外血液回路连接到患者的进入装置; 第一和第二管连接构件，用于分别连接到体外回路的第一和第二管; 第一和第二电极至少部分地由第一和第二管连接构件保持以接触流过体外血液回路的血液，第一和第二电极能够将电信号注射到体外血液回路中; 分别与第一和第二电极接触的第一和第二接触构件; 以及可操作地耦合到第一和第二接触构件的电子装置，用于施加电信号，用于监测接入装置的信号。

7. 发明授权

US07147615B2 Needle dislodgement detection 有权
标题翻译：针移位检测
公开(公告)号：US07147615B2
公开(公告)日：2006-12-12
申请号：US09888154
申请日：2001-06-22
申请人： Ramesh Wariar , Thomas P. Hartranft , Norm Cameron , Angel Lasso , Hector Caro
发明人： Ramesh Wariar , Thomas P. Hartranft , Norm Cameron , Angel Lasso , Hector Caro
IPC分类号： A61M37/00 , A61M1/00 , A61M31/00 , A61B5/00 , A61B5/04
CPC分类号： A61M5/158 , A61B5/15003 , A61B5/150503 , A61B5/15087 , A61B5/150961 , A61B5/153 , A61M1/3656 , A61M5/16831 , A61M2005/1588 , A61M2205/13 , A61M2205/18 , G01N27/121 , G01N27/223
摘要： An apparatus for detecting dislodgement of a needle inserted into a patient includes a sensor for detecting wetness due to blood and a sensor holder to secure the sensor to the patient such that the sensor detects wetness due to blood loss from the patient upon dislodgement of the needle. Methods and apparatuses for detecting, monitoring and/or controlling blood loss from a patient due to needle dislodgement are also provided.
摘要翻译：用于检测插入到患者中的针的移位的装置包括用于检测由于血液引起的湿度的传感器和用于将传感器固定到患者的传感器保持器，使得传感器检测到针头脱离时由于患者的失血引起的湿度。还提供了用于检测，监测和/或控制由于针脱落引起的患者失血的方法和装置。

8. 发明授权

US07052480B2 Access disconnection systems and methods 有权
标题翻译：访问断开连接系统和方法
公开(公告)号：US07052480B2
公开(公告)日：2006-05-30
申请号：US10120684
申请日：2002-04-10
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M37/00 , B01D11/00 , C02F1/00 , A61B5/00
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： Apparatuses, devices, systems and methods for detecting access disconnection during medical therapy are provided. The present invention includes an electric circuit coupled to, for example, a blood circuit used during dialysis therapy. The electric circuit can inject an electrical signal into the blood circuit such that changes in an electrical value in response to access disconnection, such as needle drop-out or catheter drop-out, can be effectively detected.
摘要翻译：提供了用于在药物治疗期间检测进入断开的装置，装置，系统和方法。本发明包括耦合到例如在透析治疗期间使用的血液回路的电路。电路可以将电信号注入到血液回路中，使得可以有效地检测出响应于诸如针脱落或导管脱出的进入断开的电值的变化。

9. 发明授权

US10155082B2 Enhanced signal detection for access disconnection systems 有权
公开(公告)号：US10155082B2
公开(公告)日：2018-12-18
申请号：US11676110
申请日：2007-02-16
申请人： Rodolfo G. Roger , Thomas P. Hartranft , Ramesh Wariar , Angel M. Lasso , George Lamberson
发明人： Rodolfo G. Roger , Thomas P. Hartranft , Ramesh Wariar , Angel M. Lasso , George Lamberson
IPC分类号： A61M37/00 , A61M1/34 , A61M1/16 , A61M1/36 , G01N27/07 , G01N27/10 , A61M5/168 , A61M39/10 , G01N33/49
摘要： An access disconnection system includes an extracorporeal circuit; first and second contacts provided in the extracorporeal circuit; a current source communicating with the first contact and configured to generate a current within fluid flowing through the extracorporeal circuit; and an apparatus positioned to apply a signal at multiple points along a path from the extracorporeal circuit, the signals tending to prevent at least a portion of the current from traveling through a ground path in parallel to the extracorporeal circuit.

10. 发明授权

US08708946B2 Access disconnection systems using conductive contacts 有权
标题翻译：使用导电触点访问断开系统
公开(公告)号：US08708946B2
公开(公告)日：2014-04-29
申请号：US13412249
申请日：2012-03-05
申请人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
发明人： James Han , Thomas P. Hartranft , Thomas D. Kelly , Angel Lasso
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3669 , A61M1/30 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , Y10S439/909
摘要： An extracorporeal blood machine includes a blood circuit; an access device enabling the blood circuit to be connected to a patient; first and second coupling devices for connecting to first and second tubes of the circuit; first and second electrodes held by the first and second coupling devices to contact blood flowing through the blood circuit, the electrodes enabling an electrical signal to be injected into the circuit; first and second contact members contacting the first and second electrodes, wherein at least one of the coupling devices includes a stem portion enabling at least one of the first and second contact members to contact at least one of the first and second electrodes, respectively, on an outer portion of the at least one electrode without disturbing blood flowing through the coupling device; and electronics coupled operably to the first and second contact members for applying the electrical signal.
摘要翻译：体外血液机器包括血液回路; 使得血液回路连接到患者的进入装置; 用于连接到电路的第一和第二管的第一和第二耦合装置; 由第一和第二耦合装置保持的第一和第二电极，以接触流过血液回路的血液，所述电极使得电信号被注入到电路中; 第一和第二接触构件与第一和第二电极接触，其中至少一个联接装置包括杆部分，使得第一和第二接触构件中的至少一个能够分别接触第一和第二电极中的至少一个，所述至少一个电极的外部部分，而不扰动血液流过所述联接装置; 以及可操作地耦合到第一和第二接触构件的电子装置，用于施加电信号。

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