专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20110191898A1 Compositions and Methods for Enhanced Amino Acid Levels in Plants 有权
标题翻译：植物中增强的氨基酸水平的组成和方法
公开(公告)号：US20110191898A1
公开(公告)日：2011-08-04
申请号：US12997860
申请日：2009-06-30
申请人： James H. Crowley , Barry S. Goldman , Jintai Huang , Qungang Qi , Willam D. Rapp
发明人： James H. Crowley , Barry S. Goldman , Jintai Huang , Qungang Qi , Willam D. Rapp
IPC分类号： C12N15/87 , C07H21/04 , C12N9/12 , C12N5/10 , A01H5/00
CPC分类号： C12N9/1217 , C12N15/8251 , C12N15/8254
摘要： Threonine is an essential amino acid for humans and in the animal feed industry where its levels in feed rations can significantly impact the cost of production of important meat sources, such as swine and poultry. Threonine as well as essential amino acids lysine and methionine are all synthesized via the aspartate family pathway. Aspartate kinase (AK) is the first enzyme in the pathway, and catalyzes the ATP-dependent phosphorylation of aspartate to form β-aspartyl phosphate. AK constitutes the main regulatory step controlling the metabolic flux through the pathway, and is subject to end product inhibition by Lys and/or Thr. The current invention provides a method to produce a transgenic high free threonine soybean via the overexpression of feed-back-resistant AK enzymes in developing soybean plants and seeds. These modifications provide a method to enhance both plant nitrogen metabolism and crop growth performance.
摘要翻译：苏氨酸是人类和动物饲料工业中必不可少的氨基酸，其饲料配给水平可以显着影响重要肉源的生产成本，如猪和家禽。苏氨酸以及必需氨基酸赖氨酸和甲硫氨酸均通过天冬氨酸家族途径合成。天冬氨酸激酶（AK）是途径中的第一个酶，并催化天冬氨酸形成磷酸二酯的ATP依赖性磷酸化。 AK构成控制通过该途径的代谢通量的主要调节步骤，并且受到Lys和/或Thr的最终产物抑制。本发明提供了一种在开发大豆植物和种子中通过反馈抗性AK酶的过表达产生转基因高游离苏氨酸大豆的方法。这些修饰提供了增强植物氮代谢和作物生长性能的方法。

2. 发明授权

US09090882B2 Compositions and methods for enhanced amino acid levels in plants conferred by lysine and/or threonine feedback insensitive aspartate kinase proteins 有权
标题翻译：赖氨酸和/或苏氨酸反馈不敏感天冬氨酸激酶蛋白质赋予植物氨基酸水平的组合物和方法
公开(公告)号：US09090882B2
公开(公告)日：2015-07-28
申请号：US12997860
申请日：2009-06-30
申请人： James H. Crowley , Barry S. Goldman , Jintai Huang , Qungang Qi , William D. Rapp
发明人： James H. Crowley , Barry S. Goldman , Jintai Huang , Qungang Qi , William D. Rapp
IPC分类号： C12N9/12 , C12N15/82
CPC分类号： C12N9/1217 , C12N15/8251 , C12N15/8254
摘要： Threonine is an essential amino acid for humans and in the animal feed industry where its levels in feed rations can significantly impact the cost of production of important meat sources, such as swine and poultry. Threonine as well as essential amino acids lysine and methionine are all synthesized via the aspartate family pathway. Aspartate kinase (AK) is the first enzyme in the pathway, and catalyzes the ATP-dependent phosphorylation of aspartate to form β-aspartyl phosphate. AK constitutes the main regulatory step controlling the metabolic flux through the pathway, and is subject to end product inhibition by Lys and/or Thr. The current invention provides a method to produce a transgenic high free threonine soybean via the overexpression of feedback-resistant AK enzymes in developing soybean plants and seeds. These modifications provide a method to enhance both plant nitrogen metabolism and crop growth performance.
摘要翻译：苏氨酸是人类和动物饲料工业中必不可少的氨基酸，其饲料配给水平可以显着影响重要肉源的生产成本，如猪和家禽。苏氨酸以及必需氨基酸赖氨酸和甲硫氨酸均通过天冬氨酸家族途径合成。天冬氨酸激酶（AK）是途径中的第一个酶，并催化天冬氨酸形成磷酸二酯的ATP依赖性磷酸化。 AK构成控制通过该途径的代谢通量的主要调节步骤，并且受到Lys和/或Thr的最终产物抑制。本发明提供了一种通过在开发大豆植物和种子中反馈抗性AK酶的过表达产生转基因高游离苏氨酸大豆的方法。这些修饰提供了增强植物氮代谢和作物生长性能的方法。

4. 发明申请

US20120185974A1 Xenorhabdus SP. Genome Sequences and Uses Thereof 有权
标题翻译： Xenorhabdus SP 基因组序列及其用途
公开(公告)号：US20120185974A1
公开(公告)日：2012-07-19
申请号：US13436027
申请日：2012-03-30
申请人： David R. Corbin , Barry S. Goldman , Gregory J. Hinkle , Joseph E. Huesing , Thomas M. Malvar , Karina C. Krasomil-Osterfeld , Steven C. Slater , Sergei Spiridonov
发明人： David R. Corbin , Barry S. Goldman , Gregory J. Hinkle , Joseph E. Huesing , Thomas M. Malvar , Karina C. Krasomil-Osterfeld , Steven C. Slater , Sergei Spiridonov
IPC分类号： A01H5/00 , C12N15/31 , A01H5/10 , C12N1/21 , C12N1/13 , C12N1/15 , C07K14/24 , C12N5/10
CPC分类号： C07K14/24
摘要： The present invention relates to a nucleic acid sequence from Xenorhabdus that encodes a GroEL protein. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA's, and antibodies, for example, for gene identification and analysis, and preparation of constructs.
摘要翻译：本发明涉及来自Xenorhabdus的编码GroEL蛋白的核酸序列。本发明包括非编码区中存在的核酸分子以及编码蛋白质，蛋白质片段，tRNA，tRNA片段，rRNA和rRNA片段的核酸分子。此外，蛋白质和如此编码的蛋白质的片段以及能够结合蛋白质的抗体包括在本发明中。本发明还涉及使用所公开的核酸分子，蛋白质，蛋白质片段，RNA和抗体的方法，例如用于基因鉴定和分析以及构建体的制备。

5. 发明申请

US20090205084A1 Nucleotide and amino acid sequences from xenorhabdus and uses thereof 审中-公开
标题翻译：来自番茄的核苷酸和氨基酸序列及其用途
公开(公告)号：US20090205084A1
公开(公告)日：2009-08-13
申请号：US12382648
申请日：2009-03-20
申请人： Barry S. Goldman , Karina Krasomil-Osterfeld , Thomas M. Malvar , John W. Pitkin , Steven C. Slater , Wei Wu , Jiamin Zeng
发明人： Barry S. Goldman , Karina Krasomil-Osterfeld , Thomas M. Malvar , John W. Pitkin , Steven C. Slater , Wei Wu , Jiamin Zeng
IPC分类号： A01H5/00 , C12N15/31 , C07K14/195
CPC分类号： C12N15/8286 , A01N63/00 , A01N63/02 , C07K14/24 , Y02A40/162
摘要： The invention provides isolated nucleotide sequences from Xenorhabdus nematophila species Xs86068, and, in particular, nucleotide sequences that encode insect inhibitory proteins, the insecticidal proteins, and compositions that comprise one or more of the insecticidal proteins for use in controlling insect infestation.
摘要翻译：本发明提供了来自杀线虫（Xenorhabdus nematophila）Xs86068的分离的核苷酸序列，特别是编码昆虫抑制蛋白的核苷酸序列，杀虫蛋白和包含一种或多种用于防治昆虫侵袭的杀虫蛋白的组合物。

6. 发明授权

US06833447B1 Myxococcus xanthus genome sequences and uses thereof 有权
标题翻译：黄粘球菌基因组序列及其用途
公开(公告)号：US06833447B1
公开(公告)日：2004-12-21
申请号：US09902540
申请日：2001-07-10
申请人： Barry S. Goldman , Gregory J. Hinkle , Steven C. Slater , Roger C. Wiegand
发明人： Barry S. Goldman , Gregory J. Hinkle , Steven C. Slater , Roger C. Wiegand
IPC分类号： C07H2100
CPC分类号： C12N9/0036 , C12Q1/689
摘要： The present invention relates to nucleic acid sequences from the bacterium, Myxococcus xanthus and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins and fragments of proteins. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also encompasses oligonucleotides including primers, e.g. useful for amplifying nucleic acid molecules, and collections of nucleic acid molecules and oligonucleotides, e.g. in microarrays. The invention also provides constructs and transgenic cells and organisms comprising nucleic acid molecules of the invention. The invention also relates to methods of using the disclosed nucleic acid molecules, oligonucleotides, proteins, fragments of proteins, and antibodies, for example, for gene identification and analysis, and preparation of constructs and transgenic cells and organisms.
摘要翻译：本发明涉及来自细菌，黄色索氏杆菌，特别是基因组DNA序列的核酸序列。本发明包括非编码区中存在的核酸分子以及编码蛋白质和蛋白质片段的核酸分子。此外，蛋白质和如此编码的蛋白质的片段以及能够结合蛋白质的抗体包括在本发明中。本发明还包括寡核苷酸，包括引物，例如可用于扩增核酸分子，以及核酸分子和寡核苷酸的集合，例如。在微阵列本发明还提供包含本发明的核酸分子的构建体和转基因细胞和生物体。本发明还涉及使用所公开的核酸分子，寡核苷酸，蛋白质，蛋白质片段和抗体的方法，例如用于基因鉴定和分析，以及构建体和转基因细胞和生物体的制备。

7. 发明授权

US09024113B2 Polynucleotides for expression of microbial starch branching enzymes in plants for production of plants with improved yield 有权
标题翻译：用于在植物中表达微生物淀粉分支酶的多核苷酸用于产量提高的植物
公开(公告)号：US09024113B2
公开(公告)日：2015-05-05
申请号：US11980183
申请日：2007-10-29
申请人： Yongwei Cao , Gregory J. Hinkle , Steven C. Slater , Xianfeng Chen , Barry S. Goldman
发明人： Yongwei Cao , Gregory J. Hinkle , Steven C. Slater , Xianfeng Chen , Barry S. Goldman
IPC分类号： C12N15/82 , A01H5/00 , C07K14/195
CPC分类号： C12N15/8247 , C07K14/195 , C12N15/8241 , C12N15/8243 , C12N15/8251 , C12N15/8261 , C12N15/8273 , C12N15/8274 , C12N15/8279 , Y02A40/146
摘要： Recombinant constructs and methods useful for improvement of plants are provided. In particular, recombinant constructs comprising promoters functional in plant cells positioned for expression of polynucleotides encoding starch branching enzymes from microbial sources are provided. The disclosed constructs and methods find use in production of transgenic plants to provide plants, particularly crop plants, having improved yield.
摘要翻译：提供了可用于改良植物的重组构建体和方法。特别地，提供了包含在植物细胞中起作用的启动子的重组构建体，用于从微生物来源表达编码淀粉分支酶的多核苷酸。所公开的构建体和方法可用于生产转基因植物以提供具有提高的产量的植物，特别是作物植物。

8. 发明授权

US08946511B2 Plant microRNAs and methods of use thereof 有权
公开(公告)号：US08946511B2
公开(公告)日：2015-02-03
申请号：US11974469
申请日：2007-10-12
申请人： Edwards Allen , Barry S. Goldman , Liang Guo , Sara E. Heisel , Shihshieh Huang , Sergey I. Ivashuta , David K. Kovalik , Elysia K. Krieger , James K. Roberts , Yuanji Zhang
发明人： Edwards Allen , Barry S. Goldman , Liang Guo , Sara E. Heisel , Shihshieh Huang , Sergey I. Ivashuta , David K. Kovalik , Elysia K. Krieger , James K. Roberts , Yuanji Zhang
IPC分类号： C12N15/82 , C12N15/00 , A01H5/00
CPC分类号： C12N15/113 , C12N15/8216 , C12N15/8218 , C12N15/8238 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8279 , C12N15/8286 , C12N2310/141 , C12N2320/50 , Y02A40/146 , Y02A40/162
摘要： This invention discloses novel microRNAs and their precursors, and recombinant DNA constructs including such novel miRNAs, miRNA precursors, miRNA promoters, and miRNA recognition sites corresponding to the miRNAs. Included are novel miRNA and miRNA precursors that exhibit nutrient-responsive expression. Also disclosed are miRNA decoy sequences. Further provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention and methods of controlling gene expression using recombinant DNA constructs of this invention.

9. 发明申请

US20130276161A1 TRANSGENIC PLANTS WITH ENHANCED AGRONOMIC TRAITS 审中-公开
公开(公告)号：US20130276161A1
公开(公告)日：2013-10-17
申请号：US13566369
申请日：2012-08-03
申请人： Mark Abad , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Brian Hauge , Steve He , Jacqueline E. Heard , Ping Li , Linda Lutfiyya , Bradley McDill , Robert J. Meister , Peter Morrell , Anil Neelam , Marie Petracek , John Pitkin , M. S. Rajani , Maria F. Rodriguez , Thomas Ruff , T. V. Venkatesh , Xiaoyun Wu , Jianmin Zhao , Albert Iandolino , Monica Ravanello , Kraig Brustad , Paul Chomet , Julie Davis , Virginia Ursin , T. Ambika , Shobha Char , Savitha Madappa , Dhanalakshmi Ramachandra , S. Sangeetha , K. R. Vidya , K. Vijayalakshmi , Todd Dezwaan
发明人： Mark Abad , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Brian Hauge , Steve He , Jacqueline E. Heard , Ping Li , Linda Lutfiyya , Bradley McDill , Robert J. Meister , Peter Morrell , Anil Neelam , Marie Petracek , John Pitkin , M. S. Rajani , Maria F. Rodriguez , Thomas Ruff , T. V. Venkatesh , Xiaoyun Wu , Jianmin Zhao , Albert Iandolino , Monica Ravanello , Kraig Brustad , Paul Chomet , Julie Davis , Virginia Ursin , T. Ambika , Shobha Char , Savitha Madappa , Dhanalakshmi Ramachandra , S. Sangeetha , K. R. Vidya , K. Vijayalakshmi , Todd Dezwaan
IPC分类号： C12N15/82
CPC分类号： C12N15/8273 , C07K14/415 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12Q1/6895 , C12Q2600/13 , G01N33/68 , G01N2333/415 , Y02A40/146
摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.

10. 发明申请

US20110166335A1 Xenorhabdus sp. genome sequences and uses thereof 审中-公开
标题翻译： Xenorhabdus sp。基因组序列及其用途
公开(公告)号：US20110166335A1
公开(公告)日：2011-07-07
申请号：US12289606
申请日：2008-10-30
申请人： David R. Corbin , Barry S. Goldman , Gregory J. Hinkle , Joseph E. Huesing , Thomas M. Malvar , Karina C. Krasomil-Osterfeld , Steven C. Slater , Sergei Spirodonov
发明人： David R. Corbin , Barry S. Goldman , Gregory J. Hinkle , Joseph E. Huesing , Thomas M. Malvar , Karina C. Krasomil-Osterfeld , Steven C. Slater , Sergei Spirodonov
IPC分类号： C07H21/04
CPC分类号： C07K14/24
摘要： The present invention relates to nucleic acid sequences from Xenorhabdus and, in particular, to genomic DNA sequences, and to the insecticidal Xenorhabdus strain Xs85816. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's and fragments of rRNA's. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, RNA's, and antibodies, for example, for gene identification and analysis, and preparation of constructs.
摘要翻译：本发明涉及来自Xenorhabdus，特别是基因组DNA序列的核酸序列，以及杀虫Xenorhabdus菌株Xs85816。本发明包括非编码区中存在的核酸分子以及编码蛋白质，蛋白质片段，tRNA，tRNA片段，rRNA和rRNA片段的核酸分子。此外，蛋白质和如此编码的蛋白质的片段以及能够结合蛋白质的抗体包括在本发明中。本发明还涉及使用所公开的核酸分子，蛋白质，蛋白质片段，RNA和抗体的方法，例如用于基因鉴定和分析以及构建体的制备。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式