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    • 6. 发明申请
    • Cytometer having fluid core stream position control
    • 血细胞计数器具有流体核心流位置控制
    • US20060023207A1
    • 2006-02-02
    • US10899607
    • 2004-07-27
    • James CoxBernard Fritz
    • James CoxBernard Fritz
    • G01N1/10G01N21/00
    • G01N15/1404Y10T436/118339
    • A cytometer having two or more chambers or regions in a containment structure of sheathing fluid that may be used to provide hydrodynamic focusing of another fluid having particles to be observed. The latter fluid may be a core stream which may have its lateral position in a flow or measurement channel affected by control of at least one of the parameters of the several segments of the sheathing fluid. The lateral position of the core stream may be aligned with a light source and detector for a count and observation of the particles. Electrical signals from the detector may be fed back to a processor which may control one or more parameters of the sheathing fluid in the various chambers or regions via pumps, valves, and flow and pressure sensors. This control of parameters may provide for the positioning of the core stream. This cytometer may be miniaturized.
    • 具有在护套液体的容纳结构中的两个或更多个腔室或区域的细胞计数器,其可用于提供具有待观察颗粒的另一种流体的流体动力聚焦。 后一流体可以是芯流,其可以在流动或测量通道中具有其横向位置,该流动或测量通道受到护套流体的几个段的参数中的至少一个参数的控制的影响。 核心流的横向位置可以与光源和检测器对准,用于计数和观察颗粒。 来自检测器的电信号可以被反馈到处理器,处理器可以通过泵,阀和流量和压力传感器来控制各个室或区域中的护套流体的一个或多个参数。 参数的这种控制可以提供核心流的定位。 该细胞仪可以小型化。