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1. 发明申请

US20070172388A1 PORTABLE SAMPLE ANALYZER SYSTEM 有权
标题翻译：便携式样品分析仪系统
公开(公告)号：US20070172388A1
公开(公告)日：2007-07-26
申请号：US11615874
申请日：2006-12-22
申请人： Aravind Padmanabhan , James Cox , Bernard Fritz , Tom Rezachek , Peter Reutiman , Ron Bardell , Cleopatra Cabuz
发明人： Aravind Padmanabhan , James Cox , Bernard Fritz , Tom Rezachek , Peter Reutiman , Ron Bardell , Cleopatra Cabuz
IPC分类号： G01N31/22
CPC分类号： G01N35/00603 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L9/527 , B01L2200/027 , B01L2200/04 , B01L2200/0636 , B01L2200/0684 , B01L2200/143 , B01L2200/146 , B01L2300/021 , B01L2300/0627 , B01L2300/0672 , B01L2300/0816 , B01L2300/0877 , B01L2300/14 , B01L2400/0487 , G01N15/1404 , G01N15/1459 , G01N15/1484 , G01N21/53 , G01N29/032 , G01N35/00663 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1452 , G01N2015/1486 , G01N2035/00148 , G01N2035/00247 , G01N2035/1034 , G01N2035/1053 , G01N2291/02433 , G01N2291/02836 , G01N2291/02872
摘要： A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.
摘要翻译：与样品分析仪有关的系统，更具体地说，涉及操作简单且降低向用户提供错误结果的风险的样品分析仪。在一些情况下，样品分析仪可以是便携式样品分析仪，其包括一次性流体盒。不需要对分析仪的操作员进行培训。

2. 发明申请

US20070166196A1 PORTABLE SAMPLE ANALYZER CARTRIDGE 有权
标题翻译：便携式样品分析仪盒
公开(公告)号：US20070166196A1
公开(公告)日：2007-07-19
申请号：US11615927
申请日：2006-12-22
申请人： Ron Bardell , Aravind Padmanabhan , Peter Reutiman , Tom Rezachek , James Cox , Bernard Fritz , Cleopatra Cabuz
发明人： Ron Bardell , Aravind Padmanabhan , Peter Reutiman , Tom Rezachek , James Cox , Bernard Fritz , Cleopatra Cabuz
IPC分类号： G01N33/48
CPC分类号： G01N35/085 , G01N15/1056 , G01N15/12 , G01N15/1459 , G01N15/1484 , G01N35/00603 , G01N35/00663 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1062 , G01N2015/1486 , G06F19/00
摘要： A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.
摘要翻译：与样品分析仪有关的系统，更具体地说，涉及操作简单且降低向用户提供错误结果的风险的样品分析仪。在一些情况下，样品分析仪可以是便携式样品分析仪，其包括一次性流体盒。不需要对分析仪的操作员进行培训。

3. 发明申请

US20070166195A1 ANALYZER SYSTEM 有权
标题翻译：分析仪系统
公开(公告)号：US20070166195A1
公开(公告)日：2007-07-19
申请号：US11615884
申请日：2006-12-22
申请人： Aravind Padmanabhan , James Cox , Bernard Fritz , Tom Rezachek , Peter Reutiman , Ron Bardell , Cleopatra Cabuz
发明人： Aravind Padmanabhan , James Cox , Bernard Fritz , Tom Rezachek , Peter Reutiman , Ron Bardell , Cleopatra Cabuz
IPC分类号： G01N33/48
CPC分类号： G01N35/00603 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L9/527 , B01L2200/027 , B01L2200/04 , B01L2200/0636 , B01L2200/0684 , B01L2200/143 , B01L2200/146 , B01L2300/021 , B01L2300/044 , B01L2300/0627 , B01L2300/0672 , B01L2300/0816 , B01L2300/0877 , B01L2300/14 , B01L2400/0406 , B01L2400/0481 , B01L2400/0487 , G01N15/1404 , G01N15/1459 , G01N15/1484 , G01N21/53 , G01N29/032 , G01N33/5094 , G01N35/00663 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1452 , G01N2015/1486 , G01N2035/00148 , G01N2035/00158 , G01N2035/00247 , G01N2035/1034 , G01N2035/1053 , G01N2291/02433 , G01N2291/02836 , G01N2291/02872
摘要： A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduce risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.
摘要翻译：与样品分析仪相关的系统，更具体地，涉及操作简单且降低向用户提供错误结果的风险的样品分析仪。在一些情况下，样品分析仪可以是便携式样品分析仪，其包括一次性流体盒。不需要对分析仪的操作员进行培训。

4. 发明申请

US20050255001A1 PORTABLE SAMPLE ANALYZER WITH REMOVABLE CARTRIDGE 有权
标题翻译：便携式样品分析仪与可拆卸的盒子
公开(公告)号：US20050255001A1
公开(公告)日：2005-11-17
申请号：US10908461
申请日：2005-05-12
申请人： Aravind Padmanabhan , James Cox , Bernard Fritz , Cleopatra Cabuz
发明人： Aravind Padmanabhan , James Cox , Bernard Fritz , Cleopatra Cabuz
IPC分类号： G01N15/14 , G01N33/487 , G01N33/49 , G01N33/48
CPC分类号： G01N15/1404 , G01N2015/1413 , G01N2015/1486 , Y10T436/101666
摘要： A sample analyzer with a removable and/or disposable cartridge for use at the point of care of a patient such as in a doctor's office, in the home, or elsewhere in the field. By providing a removable and/or disposable cartridge with all of the needed reagents and/or fluids, the sample analyzer can be reliably used outside of the laboratory environment, with little or no specialized training.
摘要翻译：具有可拆卸和/或一次性药筒的样品分析器，用于患者的护理点，例如在医生的办公室，家庭或现场的其他地方。通过提供具有所有需要的试剂和/或流体的可拆卸和/或一次性的筒，样品分析仪可以在实验室环境之外被可靠地使用，很少或没有专门的培训。

5. 发明申请

US20050078299A1 Dual use detectors for flow cytometry 有权
标题翻译：双重检测器用于流式细胞术
公开(公告)号：US20050078299A1
公开(公告)日：2005-04-14
申请号：US10938245
申请日：2004-09-09
申请人： Bernard Fritz , James Cox , Aravind Padmanabhan
发明人： Bernard Fritz , James Cox , Aravind Padmanabhan
IPC分类号： G01B11/27 , G01N15/00 , G01N15/02 , G01N15/14 , G01N35/08 , G01N33/48
CPC分类号： G01B11/272 , G01N15/1434 , G01N15/147 , G01N15/1484 , G01N35/085 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0088 , G01N2015/0238 , G01N2015/1075 , G01N2015/1413 , G01N2015/1452 , G01N2015/1497
摘要： An optical alignment system for aligning a light beam with a core flow in a flow stream. The flow stream may have a sheath fluid and a core flow, where the core flow has a current position within the flow stream. A light source may be used to produce a light beam, and an optical element may be used to direct the light beam at the core flow. In some illustrative embodiments, an actuator is provided for moving the optical element, light source and/or flow stream such that the light directed by the optical element is aligned with the current position of the core flow.
摘要翻译：一种用于将光束与流动流中的核心流对准的光学对准系统。流动流可以具有护套流体和芯流，其中核心流具有流动流内的当前位置。可以使用光源来产生光束，并且可以使用光学元件来引导光束在核心流动。在一些说明性实施例中，提供致动器用于移动光学元件，光源和/或流动流，使得由光学元件引导的光与核心流的当前位置对准。

6. 发明申请

US20050255600A1 PORTABLE SAMPLE ANALYZER CARTRIDGE 有权
标题翻译：便携式样品分析仪盒
公开(公告)号：US20050255600A1
公开(公告)日：2005-11-17
申请号：US10908460
申请日：2005-05-12
申请人： Aravind Padmanabhan , James Cox , Cleopatra Cabuz
发明人： Aravind Padmanabhan , James Cox , Cleopatra Cabuz
IPC分类号： B01L3/00 , B01L9/00 , G01N15/00 , G01N15/14 , G01N33/48
CPC分类号： B01L3/502715 , B01L9/527 , B01L2200/027 , B01L2200/04 , B01L2200/0636 , B01L2200/146 , B01L2300/0672 , B01L2300/0816 , B01L2300/0877 , B01L2300/14 , B01L2400/0487 , G01N15/1484 , G01N35/00722 , G01N2015/0073 , G01N2015/0084 , G01N2015/0088 , G01N2015/1413 , G01N2015/1486 , G01N2035/00891
摘要： A sample analyzer cartridge for use at a point of care of a patient such as in a doctor's office, in the home, or elsewhere in the field. By providing a removable and/or disposable cartridge with all of the needed reagents and/or fluids, the sample analyzer can be reliably used outside of the laboratory environment, with little or no specialized training.
摘要翻译：在患者的护理点使用的样品分析器盒，例如在医生的办公室，家庭或现场的其他地方。通过提供具有所有需要的试剂和/或流体的可拆卸和/或一次性的筒，样品分析仪可以在实验室环境之外被可靠地使用，很少或没有专门的培训。

7. 发明申请

US20070031289A1 MICROFLUIDIC CARD FOR RBC ANALYSIS 有权
标题翻译： RBC分析微流感卡
公开(公告)号：US20070031289A1
公开(公告)日：2007-02-08
申请号：US11428289
申请日：2006-06-30
申请人： James Cox , Aravind Padmanabhan , Ron Bardell , Christopher Zins
发明人： James Cox , Aravind Padmanabhan , Ron Bardell , Christopher Zins
IPC分类号： G01N33/00
CPC分类号： G01N15/1459 , B01L3/502723 , B01L3/502746 , B01L3/502761 , B01L3/502776 , B01L2200/0636 , B01L2200/0684 , B01L2200/10 , B01L2300/0816 , B01L2300/0887 , B01L2400/0406 , B01L2400/0415 , B01L2400/0427 , B01L2400/0487 , B01L2400/086 , G01N15/1404 , G01N15/1484 , G01N2015/0073 , G01N2015/1006 , G01N2015/1486 , G01N2015/149
摘要： A microfluidic circuit cartridge for a complete blood count, including analyses of red blood cells. Various parameters of the red blood cells may be attained. The cartridge may have sphering mechanism which has a channel or loop with a configuration for reducing or eliminating cell settling. The channel or loop may incorporate a combination of straight and curve paths in the context of gravity. The channel may alternatively have a hydrophilic or hydrophobic inside surface. Again alternatively, the channel may have an electro-wettable inside surface. Or, the channel may be subject to an electric or magnetic field. There may also be a mechanism for reducing or eliminating clumping of a sample.
摘要翻译：用于完整血细胞计数的微流体电路盒，包括红细胞分析。可以获得红细胞的各种参数。盒可以具有球形机构，其具有通道或环，其具有用于减少或消除细胞沉降的构造。通道或环路可以在重力的上下文中包含直线和曲线路径的组合。通道也可以具有亲水或疏水的内表面。或者，通道可以具有电润湿的内表面。或者，通道可能受到电场或磁场的影响。还可以存在减少或消除样品团块的机理。

8. 发明申请

US20070041013A1 A LIGHT SCATTERING AND IMAGING OPTICAL SYSTEM 有权
标题翻译：光散射和成像光学系统
公开(公告)号：US20070041013A1
公开(公告)日：2007-02-22
申请号：US11161776
申请日：2005-08-16
申请人： Bernard Fritz , James Cox , Peter Reutiman
发明人： Bernard Fritz , James Cox , Peter Reutiman
IPC分类号： G01N21/00
CPC分类号： G01N15/1463 , G01N15/1434 , G01N15/1484 , G01N21/4788 , G01N21/53 , G01N2015/1447 , G01N2015/1493 , G01N2021/4707 , G01N2021/4716 , G02B5/1819 , G02B27/4244
摘要： An optical element for conveying scattered and image light to several detectors. The optical element may have the properties of a diffractive beam splitter and imaging lens. The detected light may be from an illuminated target. Further, there may be an optical element for conveying scattered light from a target via several zones to specific detectors, respectively. The latter optical element may include a multiple annular zone diffractive structure on a hybrid lens.
摘要翻译：用于将散射和图像光传送到多个检测器的光学元件。光学元件可以具有衍射分束器和成像透镜的特性。检测到的光可以来自被照射的目标。此外，可以存在用于将来自目标的散射光分别经由若干区域传送到特定检测器的光学元件。后者的光学元件可以包括混合透镜上的多个环形区域衍射结构。

9. 发明申请

US20070146720A1 Spectrometer method and apparatus for near infrared to terahertz wavelengths 审中-公开
标题翻译：近红外到太赫兹波长的光谱仪方法和装置
公开(公告)号：US20070146720A1
公开(公告)日：2007-06-28
申请号：US11350541
申请日：2006-02-09
申请人： James Cox , Roland Wood , Bernard Fritz , Fouad Nusseibeh
发明人： James Cox , Roland Wood , Bernard Fritz , Fouad Nusseibeh
IPC分类号： G01B9/02 , G01J3/45
CPC分类号： G01J3/4531 , G01J3/0202 , G01J3/2823 , G01J3/42 , G01J3/4532
摘要： In accordance with the principles of the invention, a lamellar grating interferometer breaks the radiation down into its wavelength components. The two sets of teeth of the grating are moved relative to each other. The spectral output of the interferometer is focused on an array of detectors and data is stored for a large number of positions of the grating teeth. The collected data is then Fourier transformed to recover the spectrum of the radiation.
摘要翻译：根据本发明的原理，层状光栅干涉仪将辐射分解成其波长分量。光栅的两组齿相对于彼此移动。干涉仪的光谱输出集中在一组检测器上，数据存储在光栅齿的大量位置。然后将收集的数据进行傅里叶变换以恢复辐射的光谱。

10. 发明申请

US20060023207A1 Cytometer having fluid core stream position control 有权
标题翻译：血细胞计数器具有流体核心流位置控制
公开(公告)号：US20060023207A1
公开(公告)日：2006-02-02
申请号：US10899607
申请日：2004-07-27
申请人： James Cox , Bernard Fritz
发明人： James Cox , Bernard Fritz
IPC分类号： G01N1/10 , G01N21/00
CPC分类号： G01N15/1404 , Y10T436/118339
摘要： A cytometer having two or more chambers or regions in a containment structure of sheathing fluid that may be used to provide hydrodynamic focusing of another fluid having particles to be observed. The latter fluid may be a core stream which may have its lateral position in a flow or measurement channel affected by control of at least one of the parameters of the several segments of the sheathing fluid. The lateral position of the core stream may be aligned with a light source and detector for a count and observation of the particles. Electrical signals from the detector may be fed back to a processor which may control one or more parameters of the sheathing fluid in the various chambers or regions via pumps, valves, and flow and pressure sensors. This control of parameters may provide for the positioning of the core stream. This cytometer may be miniaturized.
摘要翻译：具有在护套液体的容纳结构中的两个或更多个腔室或区域的细胞计数器，其可用于提供具有待观察颗粒的另一种流体的流体动力聚焦。后一流体可以是芯流，其可以在流动或测量通道中具有其横向位置，该流动或测量通道受到护套流体的几个段的参数中的至少一个参数的控制的影响。核心流的横向位置可以与光源和检测器对准，用于计数和观察颗粒。来自检测器的电信号可以被反馈到处理器，处理器可以通过泵，阀和流量和压力传感器来控制各个室或区域中的护套流体的一个或多个参数。参数的这种控制可以提供核心流的定位。该细胞仪可以小型化。

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