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1. 发明授权

US08250904B2 Multi-stage injector for fluid analysis 有权
标题翻译：用于流体分析的多级注射器
公开(公告)号：US08250904B2
公开(公告)日：2012-08-28
申请号：US12039437
申请日：2008-02-28
申请人： Jagdish Shah , William H. Steinecker , Neil William Bostrom , Bhavani Raghuraman
发明人： Jagdish Shah , William H. Steinecker , Neil William Bostrom , Bhavani Raghuraman
IPC分类号： G01N30/04
CPC分类号： G01N30/20 , G01N2030/202
摘要： The present invention generally recites a method, system and apparatus for fluid analysis and more specifically recites a method system and apparatus for multistage injection of a fluid to be analyzed into a fluid analysis instrument.
摘要翻译：本发明总体上叙述了用于流体分析的方法，系统和装置，并且更具体地说明了用于将要分析的流体多级注射到流体分析仪器中的方法系统和装置。

2. 发明申请

US20090158815A1 MULTI-STAGE INJECTOR FOR FLUID ANALYSIS 有权
标题翻译：多级注射器用于流体分析
公开(公告)号：US20090158815A1
公开(公告)日：2009-06-25
申请号：US12039437
申请日：2008-02-28
申请人： Jagdish Shah , William H. Steinecker , Neil William Bostrom , Bhavani Raghuraman
发明人： Jagdish Shah , William H. Steinecker , Neil William Bostrom , Bhavani Raghuraman
IPC分类号： G01N30/04
CPC分类号： G01N30/20 , G01N2030/202
摘要： The present invention generally recites a method, system and apparatus for fluid analysis and more specifically recites a method system and apparatus for multistage injection of a fluid to be analyzed into a fluid analysis instrument.
摘要翻译：本发明总体上叙述了用于流体分析的方法，系统和装置，并且更具体地说明了用于将要分析的流体多级注射到流体分析仪器中的方法系统和装置。

3. 发明申请

US20120048108A1 Differential Acceleration Chromatography 有权
标题翻译：差示加速色谱法
公开(公告)号：US20120048108A1
公开(公告)日：2012-03-01
申请号：US13290482
申请日：2011-11-07
申请人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
发明人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
IPC分类号： B01D53/02
CPC分类号： B01D15/22 , G01N30/32 , G01N30/52 , G01N30/54 , G01N30/6065 , G01N2030/324 , G01N2030/524
摘要： Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.
摘要翻译：描述了通过新技术改进色谱分离的方法和相关系统。分离的改进主要是由于提供了被分离的部件的差速加速。描述了用于提供差速加速度的各种系统和方法，其包括：将塔的横截面增加到塔出口，改变柱内的固定相的厚度或其它组成，以及沿着柱提供温度和/或流动相速度梯度柱。

4. 发明授权

US08778059B2 Differential acceleration chromatography 有权
标题翻译：差速加速色谱法
公开(公告)号：US08778059B2
公开(公告)日：2014-07-15
申请号：US11949362
申请日：2007-12-03
申请人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
发明人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
IPC分类号： G01N30/60 , B01D53/02 , G01N30/26 , G01N30/56
CPC分类号： B01D15/22 , G01N30/32 , G01N30/52 , G01N30/54 , G01N30/6065 , G01N2030/324 , G01N2030/524
摘要： Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.
摘要翻译：描述了通过新技术改进色谱分离的方法和相关系统。分离的改进主要是由于提供了被分离的部件的差速加速。描述了用于提供差速加速度的各种系统和方法，其包括：将塔的横截面增加到塔出口，改变柱内的固定相的厚度或其它组成，以及沿着柱提供温度和/或流动相速度梯度柱。

5. 发明授权

US08512457B2 Differential acceleration chromatography 有权
标题翻译：差速加速色谱法
公开(公告)号：US08512457B2
公开(公告)日：2013-08-20
申请号：US13290482
申请日：2011-11-07
申请人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
发明人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
IPC分类号： B01D53/02 , G01N30/02 , G01N30/56
CPC分类号： B01D15/22 , G01N30/32 , G01N30/52 , G01N30/54 , G01N30/6065 , G01N2030/324 , G01N2030/524
摘要： Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.
摘要翻译：描述了通过新技术改进色谱分离的方法和相关系统。分离的改进主要是由于提供了被分离的部件的差速加速。描述了用于提供差速加速度的各种系统和方法，其包括：将塔的横截面增加到塔出口，改变柱内的固定相的厚度或其它组成，以及沿着柱提供温度和/或流动相速度梯度柱。

6. 发明申请

US20090139934A1 DIFFERENTIAL ACCELERATION CHROMATOGRAPHY 有权
标题翻译：差异加速色谱法
公开(公告)号：US20090139934A1
公开(公告)日：2009-06-04
申请号：US11949362
申请日：2007-12-03
申请人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
发明人： William H. Steinecker , Jagdish Shah , Oleg Zhdaneev , Gordon R. Lambertus , Hua Chen
IPC分类号： B01D15/08
CPC分类号： B01D15/22 , G01N30/32 , G01N30/52 , G01N30/54 , G01N30/6065 , G01N2030/324 , G01N2030/524
摘要： Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.
摘要翻译：描述了通过新技术改进色谱分离的方法和相关系统。分离的改进主要是由于提供了被分离的部件的差速加速。描述了用于提供差速加速度的各种系统和方法，其包括：将塔的横截面增加到塔出口，改变柱内的固定相的厚度或其它组成，以及沿着柱提供温度和/或流动相速度梯度柱。

7. 发明授权

US08377309B2 Methods and apparatus for making a chromatography column 有权
标题翻译：制备色谱柱的方法和设备
公开(公告)号：US08377309B2
公开(公告)日：2013-02-19
申请号：US12947528
申请日：2010-11-16
申请人： William H. Steinecker
发明人： William H. Steinecker
IPC分类号： B01D15/08
CPC分类号： B01D15/206 , B05D7/222 , B05D2490/60 , G01N30/6073 , G01N2030/567
摘要： Methods for depositing a stationary phase in a tube for chromatography, in particular, as a variable gradient column are disclosed. The methods include providing a tube having a first end and a second end, the tube containing a fluid composition comprising a stationary phase precursor and a solvent, connecting the first end of the tube to a flow device, removing the solvent from a meniscus of the fluid composition, the solvent exiting the tube at the second end, and operating the flow device while removing the solvent such that the amount of the stationary phase precursor deposited within the tube changes as the meniscus retreats within the tube to deposit a stationary phase having a thickness gradient along the length of the interior of the tube.
摘要翻译：公开了在用于色谱的管中沉积固定相的方法，特别是作为可变梯度柱。所述方法包括提供具有第一端和第二端的管，所述管含有包含固定相前体和溶剂的流体组合物，将管的第一端连接到流动装置，从溶液的弯液面中除去溶剂流体组合物，溶剂在第二端离开管，并且在除去溶剂的同时操作流动装置，使得沉积在管内的固定相前体的量随着管内的弯液面的后退而变化，以沉积具有沿着管内部长度的厚度梯度。

8. 发明申请

US20120118805A1 METHODS AND APPARATUS FOR MAKING A CHROMATOGRAPHY COLUMN 有权
标题翻译：制作色谱柱的方法和装置
公开(公告)号：US20120118805A1
公开(公告)日：2012-05-17
申请号：US12947374
申请日：2010-11-16
申请人： William H. Steinecker
发明人： William H. Steinecker
IPC分类号： B01D15/08 , B05D7/22
CPC分类号： B01D15/206 , G01N30/56 , G01N30/6065 , G01N30/6078 , G01N2030/567
摘要： Methods for depositing a stationary phase in a tube for chromatography, in particular, as a variable gradient column are disclosed. The methods include providing a tube, loading the tube with a concentration gradient of a stationary phase precursor along its length, and removing the solvent such that the stationary phase precursor is deposited within the tube as a stationary phase to form a chromatography column. The concentration gradient is formed by combining at least a first fluid and a second fluid, with the first fluid containing the stationary phase precursor in a solvent.
摘要翻译：公开了在用于色谱的管中沉积固定相的方法，特别是作为可变梯度柱。所述方法包括提供管，沿其长度加载具有固定相前体的浓度梯度的管，并除去溶剂，使得固定相前体作为固定相沉积在管内以形成色谱柱。浓度梯度通过将至少第一流体和第二流体组合而形成，其中第一流体包含固定相前体在溶剂中。

9. 发明授权

US09638681B2 Real-time compositional analysis of hydrocarbon based fluid samples 有权
公开(公告)号：US09638681B2
公开(公告)日：2017-05-02
申请号：US13249535
申请日：2011-09-30
申请人： Oleg Zhdaneev , Christopher Harrison , Youxiang Zuo , Dingan Zhang , William H. Steinecker , Gordon R. Lambertus , Neil Bostrom
发明人： Oleg Zhdaneev , Christopher Harrison , Youxiang Zuo , Dingan Zhang , William H. Steinecker , Gordon R. Lambertus , Neil Bostrom
IPC分类号： E21B49/08 , E21B49/10 , G01N33/28 , G01N21/3504 , G01N30/86 , G01N21/359 , G01N21/64 , G01N21/3577 , G01N30/88
CPC分类号： G01N33/2823 , E21B49/10 , G01N21/3504 , G01N21/3577 , G01N21/359 , G01N21/643 , G01N30/8658 , G01N2030/8854
摘要： Accurate, real-time formation fluids analysis can be accomplished using the systems and techniques described herein. A fluid analyzer includes a first mode of analysis, such as an optical analyzer, configured to determine a physical (optical) property of a fluid sample. The fluid analyzer also includes another mode of analysis, such as a composition analyzer, such as a gas chromatograph, configured to determine a component composition of the fluid sample. A data processor is configured to determine a quantity, such as a weight percentage, of a target component of the fluid sample in response results obtained from the first and second modes of analysis. Beneficially, the results are obtained at least in near real-time, allowing for interim results, such as results from the first analyzer to be used for one or more of tuning the compositional analyzer and for implementing quality control.

10. 发明申请

US20130206667A1 APPARATUS FOR MAKING A CHROMATOGRAPHY COLUMN 审中-公开
标题翻译：用于制作色谱柱的装置
公开(公告)号：US20130206667A1
公开(公告)日：2013-08-15
申请号：US13755594
申请日：2013-01-31
申请人： William H. Steinecker
发明人： William H. Steinecker
IPC分类号： B01D15/22
CPC分类号： B01D15/22 , B01D15/206 , B05D7/222 , B05D2490/60 , G01N30/6052 , G01N30/6065 , G01N30/6073 , G01N2030/567
摘要： Variable geometry columns for chromatography are disclosed that include a tube having an interior surface and an inlet end and an outlet end, a stationary phase deposited along substantially the length of the interior surface of the tube, and/or deposited on surface area-increasing members positioned within the tube. The resulting column has a gradually enlarging cross-sectional area that is narrower at the inlet end than toward the outlet end attributable to (1) the cross-section of the tube, (2) a variable deposition of the stationary phase, or (3) a combination thereof.
摘要翻译：公开了用于层析的可变几何柱，其包括具有内表面和入口端和出口端的管，沿着管的内表面的大致长度沉积的固定相和/或沉积在表面积增加构件位于管内。所得到的柱具有逐渐扩大的横截面积，其在入口端处比朝向出口端窄，归因于（1）管的横截面，（2）固定相的可变沉积，或（3 ）其组合。

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