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1. 发明授权

US08288357B2 Use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers 有权
标题翻译：使用白三烯B4受体BLT2抑制剂治疗人类癌症
公开(公告)号：US08288357B2
公开(公告)日：2012-10-16
申请号：US12450335
申请日：2008-03-24
申请人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
发明人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
IPC分类号： A61K31/70 , C07H21/02 , C07H21/04
CPC分类号： C07K16/28 , C07K14/705 , C12N15/113 , C12N15/1138 , C12N2310/11 , C12N2310/14 , C12N2310/315
摘要： The present invention relates to a new use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers. More particularly, the present invention relates to a pharmaceutical composition for treating human cancers comprising BLT2 inhibitors and a method for treating human cancers using BLT2 inhibitors.The present inventors revealed the role of BLT2 as a survival factor of human cancers, such as bladder, prostate, pancreatic, and breast cancer and found that the BLT2 inhibitors can be used as anti-cancer drugs. The present inventors revealed that BLT2 has an important role in metastasis of cancer cells and angiogenesis of tumor and demonstrated that the anti-cancer activity of the BLT2 inhibitors is accomplished by inducing the apoptosis of cancer cells, inhibiting the metastasis of cancer cells, or inhibiting the angiogenesis of tumor.
摘要翻译：本发明涉及白三烯B4受体BLT2抑制剂治疗人类癌症的新用途。更具体地，本发明涉及用于治疗包含BLT2抑制剂的人类癌症的药物组合物和使用BLT2抑制剂治疗人类癌症的方法。本发明人揭示了BLT2作为人类癌症如膀胱，前列腺，胰腺和乳腺癌的存活因子的作用，发现BLT2抑制剂可用作抗癌药物。本发明人发现BLT2在癌细胞转移和肿瘤血管生成中具有重要作用，并且证明BLT2抑制剂的抗癌活性是通过诱导癌细胞的凋亡，抑制癌细胞的转移或抑制肿瘤血管生成。

2. 发明申请

US20120213788A1 USE OF INHIBITORS OF LEUKOTRIENE B4 RECEPTOR BLT2 FOR TREATING HUMAN CANCERS 有权
标题翻译：用于治疗人类癌症的白介素B4受体BLT2的抑制剂的使用
公开(公告)号：US20120213788A1
公开(公告)日：2012-08-23
申请号：US13316098
申请日：2011-12-09
申请人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
发明人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
IPC分类号： A61K39/395 , A61K31/7088 , A61K31/713 , G01N33/574 , C07K16/28 , C07H21/02 , C12Q1/68 , C12Q1/02 , A61P35/00 , C12N5/02
CPC分类号： A61K31/713 , A61K31/7088 , A61K2039/505 , C07K16/28 , C07K2317/34 , C07K2317/73 , C07K2317/76 , C12N15/1138 , C12N2310/11 , C12N2310/14 , G01N33/57407 , G01N33/92 , G01N2333/705 , G01N2500/00
摘要： The present invention relates to the use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers. More particularly, the present invention relates to a pharmaceutical composition for treating human cancers comprising BLT2 inhibitors and a method for treating human cancers using BLT2 inhibitors.
摘要翻译：本发明涉及白三烯B4受体BLT2抑制剂用于治疗人类癌症的用途。更具体地，本发明涉及用于治疗包含BLT2抑制剂的人类癌症的药物组合物和使用BLT2抑制剂治疗人类癌症的方法。

3. 发明授权

US08518889B2 Method of treating cancer with antibodies against long-form leukotriene B4 receptor BLT2 有权
标题翻译：用长型白三烯B4受体BLT2抗体治疗癌症的方法
公开(公告)号：US08518889B2
公开(公告)日：2013-08-27
申请号：US13316098
申请日：2011-12-09
申请人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
发明人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
IPC分类号： A61P35/00 , A61K39/00 , A61K39/395 , C07K16/28 , C07K16/30
CPC分类号： A61K31/713 , A61K31/7088 , A61K2039/505 , C07K16/28 , C07K2317/34 , C07K2317/73 , C07K2317/76 , C12N15/1138 , C12N2310/11 , C12N2310/14 , G01N33/57407 , G01N33/92 , G01N2333/705 , G01N2500/00
摘要： The present invention relates to the use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers. More particularly, the present invention relates to a pharmaceutical composition for treating human cancers comprising BLT2 inhibitors and a method for treating human cancers using BLT2 inhibitors.
摘要翻译：本发明涉及白三烯B4受体BLT2抑制剂用于治疗人类癌症的用途。更具体地，本发明涉及用于治疗包含BLT2抑制剂的人类癌症的药物组合物和使用BLT2抑制剂治疗人类癌症的方法。

4. 发明申请

US20110223152A1 USE OF INHIBITORS OF LEUKOTRIENE B4 RECEPTOR BLT2 FOR TREATING HUMAN CANCERS 有权
标题翻译：用于治疗人类癌症的白介素B4受体BLT2的抑制剂的使用
公开(公告)号：US20110223152A1
公开(公告)日：2011-09-15
申请号：US12450335
申请日：2008-03-24
申请人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
发明人： Jae-Hong Kim , Jung-A Choi , Eun-Young Kim , Geun-Young Kim , Chul-Min Kim , Ji-Min Seo , Hyun-Ju Kim , Jin-Wook Lee
IPC分类号： A61K39/395 , A61K31/41 , A61K31/713 , A61K31/704 , A61P35/00 , C12Q1/02 , C07H21/00 , C07K16/28 , C12Q1/68
CPC分类号： C07K16/28 , C07K14/705 , C12N15/113 , C12N15/1138 , C12N2310/11 , C12N2310/14 , C12N2310/315
摘要： The present invention relates to a new use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers. More particularly, the present invention relates to a pharmaceutical composition for treating human cancers comprising BLT2 inhibitors and a method for treating human cancers using BLT2 inhibitors.The present inventors revealed the role of BLT2 as a survival factor of human cancers, such as bladder, prostate, pancreatic, and breast cancer and found that the BLT2 inhibitors can be used as anti-cancer drugs. The present inventors revealed that BLT2 has an important role in metastasis of cancer cells and angiogenesis of tumor and demonstrated that the anti-cancer activity of the BLT2 inhibitors is accomplished by inducing the apoptosis of cancer cells, inhibiting the metastasis of cancer cells, or inhibiting the angiogenesis of tumor.
摘要翻译：本发明涉及白三烯B4受体BLT2抑制剂治疗人类癌症的新用途。更具体地，本发明涉及用于治疗包含BLT2抑制剂的人类癌症的药物组合物和使用BLT2抑制剂治疗人类癌症的方法。本发明人揭示了BLT2作为人类癌症如膀胱，前列腺，胰腺和乳腺癌的存活因子的作用，发现BLT2抑制剂可用作抗癌药物。本发明人发现BLT2在癌细胞转移和肿瘤血管生成中具有重要作用，并且证明BLT2抑制剂的抗癌活性是通过诱导癌细胞的凋亡，抑制癌细胞的转移或抑制肿瘤血管生成。

5. 发明授权

US07263263B2 Method for monitoring spin imparted on optical fiber and method for making optical fiber by using the same 有权
标题翻译：用于监测在光纤上施加的自旋的方法及其制造方法
公开(公告)号：US07263263B2
公开(公告)日：2007-08-28
申请号：US10629893
申请日：2003-07-29
申请人： Chul-Min Kim , Myung-Ho Jang , Sang-Joon Bae , Young-Il Kwon , Won-Sang Yoo , Joon-Keun Lee
发明人： Chul-Min Kim , Myung-Ho Jang , Sang-Joon Bae , Young-Il Kwon , Won-Sang Yoo , Joon-Keun Lee
IPC分类号： G02B6/02
CPC分类号： G02B6/02285 , C03B37/0253 , C03B37/02745 , C03B37/032 , C03B2203/19 , C03B2203/36 , C03B2205/06 , G01M11/37 , G01N21/47
摘要： A method for monitoring a spin imparted on an optical fiber in order to reduce Polarization Mode Dispersion (PMD) includes the steps of imparting a spin on a high-temperature optical fiber which is drawn from a preform, photographing a dispersion pattern peculiar to the spun optical fiber with a camera from scattered light naturally generated by the spin imparted on the optical fiber, and displaying the photographed dispersion pattern. The method enables monitoring of rate and period of the spin imparted on the optical fiber on the basis of the displayed dispersion pattern.
摘要翻译：为了减少偏振模色散（PMD），用于监测施加在光纤上的自旋的方法包括以下步骤：在从预成型件拉出的高温光纤上进行自旋，拍摄纺丝特有的分散图案具有照相机的光纤由散射光自然产生，通过旋转赋予光纤，并显示拍摄的色散图案。该方法能够基于所显示的色散图案来监视在光纤上施加的旋转的速率和周期。

6. 发明授权

US06173110B2 Magnetic recording and reproduction apparatus having a recording characteristic correction function of a video signal 失效
标题翻译：具有视频信号的记录特性校正功能的磁记录和再现装置
公开(公告)号：US06173110B2
公开(公告)日：2001-01-09
申请号：US09086067
申请日：1998-05-29
申请人： Chul-Min Kim , Masamitsu Seki
发明人： Chul-Min Kim , Masamitsu Seki
IPC分类号： H04N9793
CPC分类号： H04N17/06 , H04N9/83
摘要： A magnetic recording and reproduction apparatus corrects recording characteristics of a video signal. The apparatus comprises a luminance test signal generator for generating a frequency-modulated luminance test signal using a predetermined voltage, and a chroma test signal generator for generating a chroma test signal having a lower frequency. A recording level adjuster respectively adjusts levels of the frequency-modulated luminance test signal and the chroma test signal based on corresponding luminance and chroma recording levels. A recording unit mixes signals level-adjusted by the recording level adjuster to record a mixed test signal on a magnetic tape. A readout and preamplifying unit reads out the mixed test signal from the magnetic tape and preamplifies the read-out signal. A controller determines an optimal luminance recording level and an optimal chroma recording level to record a video signal on the magnetic tape based on the mixed test signal, and supplies the determined luminance recording level and chroma recording level to the recording level adjusting means. Accordingly, the apparatus sets optimal recording levels of the video signal capable of maximizing enhancement of the performance of the tape within a short period of time, and records the video signal, thereby improving a signal-to-noise ratio of the luminance signal and the color signal.
摘要翻译：磁记录和再现装置校正视频信号的记录特性。该装置包括用于使用预定电压产生调频亮度测试信号的亮度测试信号发生器和用于产生具有较低频率的色度测试信号的色度测试信号发生器。记录电平调节器基于对应的亮度和色度记录电平分别调节调频亮度测试信号和色度测试信号的电平。记录单元将由记录电平调节器进行了电平调整的信号混合，以将混合的测试信号记录在磁带上。读出和前置放大单元读出来自磁带的混合测试信号并对读出的信号进行预放大。控制器基于混合测试信号确定最佳亮度记录水平和最佳色度记录水平以将视频信号记录在磁带上，并将所确定的亮度记录水平和色度记录水平提供给记录水平调节装置。因此，该装置设置能够在短时间内使磁带的性能最大化的视频信号的最佳记录电平，并且记录视频信号，从而提高亮度信号和信号的信噪比彩色信号。

7. 发明申请

US20060113184A1 Lead frame plating apparatus 审中-公开
标题翻译：引线框电镀装置
公开(公告)号：US20060113184A1
公开(公告)日：2006-06-01
申请号：US10538391
申请日：2004-03-17
申请人： Won-Chan Park , Chul-Min Kim
发明人： Won-Chan Park , Chul-Min Kim
IPC分类号： C25B9/00 , C25C7/00
CPC分类号： C25D5/022 , C25D5/026 , C25D17/02 , H01L23/49582 , H01L2924/0002 , H01L2924/00
摘要： Disclosed herein is a lead frame plating apparatus. The lead frame plating apparatus comprises side inlets provided in the diagonal direction at opposite sides for supplying plating solution, a flow mixing room defined with an inner space in the longitudinal direction, a plating solution outlet for guiding the plating solution in the direction of nozzles, and a plating solution distribution part provided with the nozzles at an upper part of the plating solution outlet. Each nozzle is provided, at the lower end thereof, with a divergent-shaped expansion tube such that an inner diameter of the inlet of the expansion tube, larger than that of the nozzle, gradually decreases to an extent of the inner diameter of the nozzle. The lead frame plating apparatus supplies the plating solution through the nozzles with a uniform distribution.
摘要翻译：这里公开了一种引线框电镀装置。引线框电镀装置包括在相对侧的对角方向上设置用于供应电镀液的侧入口，在纵向方向上限定有内部空间的流动混合室，用于沿喷嘴方向引导电镀液的电镀液出口，以及在电镀液出口的上部具有喷嘴的电镀液分配部。每个喷嘴在其下端处设置有发散型膨胀管，使得膨胀管的入口的内径大于喷嘴的入口的内径逐渐减小到喷嘴的内径的程度。引线框电镀装置通过喷嘴以均匀的分布供给电镀液。

8. 发明申请

US20050233671A1 BUBBLE BLOWER AND BUBBLE BLOWER EQUIPPED VEHICLE 失效
标题翻译：泡沫鼓风机和鼓风机配备的汽车
公开(公告)号：US20050233671A1
公开(公告)日：2005-10-20
申请号：US10871596
申请日：2004-06-21
申请人： Chul-Min Kim , Haeng-Chul Shin
发明人： Chul-Min Kim , Haeng-Chul Shin
IPC分类号： A63H17/26 , A63H33/28 , F21V33/00
CPC分类号： F21V33/008 , A63H33/28 , F21Y2115/10
摘要： A bubble blower and a bubble blower equipped vehicle includes: a case; a discharge hole adapted to discharge bubbles, the discharge hole being arranged in a front portion of the case; a detachable cartridge filled with a bubble producing liquid and affixed to a lower portion of the case; a supply path arranged between the detachable cartridge and the discharge hole and adapted to transfer the bubble producing liquid from the detachable cartridge; a blower fan arranged within an inner portion of the case and adapted to produce a stream of air, the bubble producing liquid being sprayed into the stream of air from the supply path to produce bubbles; a handle arranged on a lower portion of the case; a switch arranged on one side of an outer face of the case and adapted to operate the fan; a reflector plate arranged to encircle the discharge hole; and a plurality of Light Emitting Diodes (LEDs) arranged on the reflector plate.
摘要翻译：气泡鼓风机和鼓风机配备车辆包括：壳体; 排出孔，其适于排出气泡，排出孔布置在壳体的前部; 填充有产生气泡的液体并固定到壳体的下部的可拆卸筒; 供给路径，其布置在所述可拆卸筒和排出孔之间，并且适于从可拆卸筒传送产生气泡的液体; 鼓风扇布置在壳体的内部并适于产生空气流，气泡产生液体从供应路径喷射到空气流中以产生气泡; 手柄，布置在壳体的下部; 布置在所述壳体的外表面的一侧并且适于操作所述风扇的开关; 布置成环绕排出孔的反射板; 以及布置在反射板上的多个发光二极管（LED）。

9. 发明授权

US06953376B1 Bubble blower and bubble blower equipped vehicle 失效
标题翻译：鼓风机和鼓风机配备车辆
公开(公告)号：US06953376B1
公开(公告)日：2005-10-11
申请号：US10871596
申请日：2004-06-21
申请人： Chul-Min Kim , Haeng-Chul Shin
发明人： Chul-Min Kim , Haeng-Chul Shin
IPC分类号： A63H17/26 , A63H33/28 , F21V33/00
CPC分类号： F21V33/008 , A63H33/28 , F21Y2115/10
摘要： A bubble blower and a bubble blower equipped vehicle includes: a case; a discharge hole adapted to discharge bubbles, the discharge hole being arranged in a front portion of the case; a detachable cartridge filled with a bubble producing liquid and affixed to a lower portion of the case; a supply path arranged between the detachable cartridge and the discharge hole and adapted to transfer the bubble producing liquid from the detachable cartridge; a blower fan arranged within an inner portion of the case and adapted to produce a stream of air, the bubble producing liquid being sprayed into the stream of air from the supply path to produce bubbles; a handle arranged on a lower portion of the case; a switch arranged on one side of an outer face of the case and adapted to operate the fan; a reflector plate arranged to encircle the discharge hole; and a plurality of Light Emitting Diodes (LEDs) arranged on the reflector plate.
摘要翻译：气泡鼓风机和鼓风机配备车辆包括：壳体; 排出孔，其适于排出气泡，排出孔布置在壳体的前部; 填充有产生气泡的液体并固定到壳体的下部的可拆卸筒; 供给路径，其布置在所述可拆卸筒和排出孔之间，并且适于从可拆卸筒传送产生气泡的液体; 鼓风扇布置在壳体的内部并适于产生空气流，气泡产生液体从供应路径喷射到空气流中以产生气泡; 手柄，布置在壳体的下部; 布置在所述壳体的外表面的一侧并且适于操作所述风扇的开关; 布置成环绕排出孔的反射板; 以及布置在反射板上的多个发光二极管（LED）。

10. 发明授权

US07823419B2 Optical fiber drawing furnace with gas flow tubes 有权
标题翻译：光纤拉丝炉采用气流管
公开(公告)号：US07823419B2
公开(公告)日：2010-11-02
申请号：US12365057
申请日：2009-02-03
申请人： Sang-Joon Bae , Young-Il Kwon , Joon-Keun Lee , Chul-Min Kim , Myung-Ho Jang
发明人： Sang-Joon Bae , Young-Il Kwon , Joon-Keun Lee , Chul-Min Kim , Myung-Ho Jang
IPC分类号： C03B37/029
CPC分类号： C03B37/029 , C03B2203/36 , C03B2205/81 , C03B2205/83 , C03B2205/90 , C03B2205/96 , C03B2205/98
摘要： A furnace for drawing an optical fiber includes a body having an upper and lower openings for supplying a preform and discharging a drawn optical fiber, a heating unit installed in the body for receiving and melting the preform, an atmosphere blocking tube installed to the lower opening for discharging the drawn optical fiber and blocking the optical fiber from the atmosphere, an upper introduction port formed at an upper portion of the body for introducing an inert gas toward the preform and partially discharged outside through a gap between the preform and the upper opening, a central and lower introduction ports formed at central and lower portions for introducing an inert gas into the body, a first flow guiding means for guiding the inert gas introduced through the central introduction port upward and then flowed down along a surface of the preform, and a second flow guiding means for guiding the inert gas introduced through the lower introduction port upward and then discharged outside through the atmosphere blocking tube along a surface of the drawn optical fiber.
摘要翻译：用于拉制光纤的炉包括具有用于供应预成型件和排出拉制的光纤的上开口和下开口的主体，安装在本体中用于接收和熔化预成型件的加热单元，安装到下开口的气氛阻挡管为了排出拉制的光纤并将光纤从大气中阻挡，形成在主体的上部的上部引入口用于向预成型件引入惰性气体，并通过预成型件和上部开口之间的间隙部分地排出外部，形成在中部和下部的用于将惰性气体引入体内的中心和下部引入口，用于引导通过中心引入口引入的惰性气体沿着预成型件的表面向下流动的第一流动引导装置，以及用于引导通过下引入口引入的惰性气体然后排出的第二流引导装置沿着拉制的光纤的表面通过气氛阻挡管。

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