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1. 发明申请

US20060147999A1 Method and apparatus for homology-based complex detection in a protein-protein interaction network 审中-公开
标题翻译：蛋白质 - 蛋白质相互作用网络中基于同源性复合物检测的方法和装置
公开(公告)号：US20060147999A1
公开(公告)日：2006-07-06
申请号：US11296886
申请日：2005-12-07
申请人： Jae Choi , Jong Park , Jae Jung , Seon Park
发明人： Jae Choi , Jong Park , Jae Jung , Seon Park
IPC分类号： G01N33/53 , G06F19/00
CPC分类号： G16B20/00
摘要： Provided are a method and a apparatus for detecting a protein complex using a similarity between different proteins in a protein-protein interaction network. The method includes: (a) producing a virtual complex of a specific organism by mapping proteins contained in a complex of a different organism into proteins of the specific organism using homology information between different proteins; and (b) searching for the produced virtual complex in the protein-protein interaction network of the specific organism.
摘要翻译：提供了使用蛋白质 - 蛋白质相互作用网络中的不同蛋白质之间的相似性来检测蛋白质复合物的方法和装置。该方法包括：（a）使用不同蛋白质之间的同源性信息，通过将不同生物体的复合物中包含的蛋白质映射到特定生物体的蛋白质来产生特定生物体的虚拟复合物; 和（b）搜索特定生物体的蛋白质 - 蛋白质相互作用网络中产生的虚拟复合物。

2. 发明申请

US20070136003A1 Method and system of verifying protein-protein interaction using protein homology relationship 审中-公开
标题翻译：使用蛋白质同源关系验证蛋白质 - 蛋白质相互作用的方法和系统
公开(公告)号：US20070136003A1
公开(公告)日：2007-06-14
申请号：US11635581
申请日：2006-12-08
申请人： Jae Choi , Jong Park , Seon Park
发明人： Jae Choi , Jong Park , Seon Park
IPC分类号： G06F19/00
CPC分类号： G16B20/00 , G16B30/00
摘要： Provided are a method and system for verifying a protein-protein interaction of a species by using a homology relationship between proteins of the species and proteins of other species. The method includes generating one or more protein homology relationships between source proteins of a species and heterogeneous proteins of one or more other species, generating one or more heterogeneous protein interactions corresponding to a specific source protein interaction using the generated one or more protein homology relationships, and determining whether the generated one or more heterogeneous protein interactions are present between the heterogeneous proteins of one or more species. Accordingly, a protein-protein interaction of a specific high-rank organism can be automatically verified by using protein-protein interactions of a low-rank organism that can be easily determined at low costs, without an expensive biological experiment.
摘要翻译：提供了一种通过使用物种的蛋白质和其他物种的蛋白质之间的同源性关系来验证物种的蛋白质 - 蛋白质相互作用的方法和系统。该方法包括在物种的源蛋白质和一种或多种其他物种的异质蛋白质之间产生一种或多种蛋白质同源性关系，使用所产生的一种或多种蛋白质同源性关系产生对应于特定来源蛋白质相互作用的一种或多种异质蛋白质相互作用，以及确定所产生的一种或多种异质蛋白质相互作用是否存在于一种或多种物质的异质蛋白质之间。因此，通过使用可以以低成本容易地测定的低等级生物体的蛋白质 - 蛋白质相互作用，可以自动验证特定高级生物体的蛋白质 - 蛋白质相互作用，而无需昂贵的生物实验。

3. 发明申请

US20070136002A1 Method and system for synchronizing protein information of PPI network DB 审中-公开
标题翻译： PPI网络数据库的蛋白质信息同步方法和系统
公开(公告)号：US20070136002A1
公开(公告)日：2007-06-14
申请号：US11635579
申请日：2006-12-08
申请人： Jae Choi , Jong Park , Myung Lim , Seon Park
发明人： Jae Choi , Jong Park , Myung Lim , Seon Park
IPC分类号： G06F19/00
CPC分类号： G16B50/00 , G16B20/00
摘要： A method and system for keeping a protein-protein interaction (PPI) network database (DB) up-to-date by synchronizing protein information present in the PPI network DB with protein information present in a public DB which is frequently updated and is provided to the public are provided. The method of synchronizing protein information of a protein-protein interaction (PPI) network database (DB) includes: (a) choosing a protein from a PPI network DB which stores a plurality of pieces of PPI information; (b) receiving up-to-date protein information corresponding to the chosen protein from a global protein DB which stores a plurality of pieces of up-to-date protein information that can be provided to the public, and keeping the local protein DB up-to-date by performing a global synchronization operation on a local protein DB such that protein information which corresponds to the chosen protein and is present in the local protein DB can be updated with the received up-to-date protein information, the local protein DB storing a plurality of pieces of protein information corresponding to the PPI network DB; and (c) receiving updated protein information obtained through the global synchronization operation from the local protein DB, and keeping the PPI network up-to-date by performing a local synchronization operation on the PPI network DB such that protein information which corresponds to the chosen protein and is present in the PPI network DB can be updated with the received updated protein information.
摘要翻译：通过将PPI网络DB中存在的蛋白质信息与存在于公共DB中的蛋白质信息同步来保持蛋白质 - 蛋白质相互作用（PPI）网络数据库（DB）的最新方法和系统，所述蛋白质信息经常被更新并提供给公众提供。蛋白质 - 蛋白质相互作用（PPI）网络数据库（DB）的同步蛋白质信息的方法包括：（a）从存储多条PPI信息的PPI网络DB中选择蛋白质; （b）从全球蛋白质DB接收对应于所选择的蛋白质的最新蛋白质信息，其存储可以提供给公众的多条最新蛋白质信息，并保持局部蛋白质DB向上通过对局部蛋白质DB进行全局同步操作，使得可以用接收到的最新蛋白质信息来更新对应于所选蛋白质并存在于局部蛋白质DB中的蛋白质信息，局部蛋白质 DB存储对应于PPI网络DB的多条蛋白质信息; 和（c）从本地蛋白质DB接收通过全局同步操作获得的更新的蛋白质信息，并且通过对PPI网络DB执行本地同步操作来保持PPI网络是最新的，使得与所选择的蛋白质信息相对应的蛋白质信息蛋白质并存在于PPI网络DB中，可以用接收到的更新的蛋白质信息进行更新。

4. 发明申请

US20050137808A1 Method for conceptualizing protein interaction networks using gene ontology 审中-公开
标题翻译：使用基因本体概念化蛋白质相互作用网络的方法
公开(公告)号：US20050137808A1
公开(公告)日：2005-06-23
申请号：US10971872
申请日：2004-10-22
申请人： Jae Choi , Seon Park
发明人： Jae Choi , Seon Park
IPC分类号： G01N33/68 , G06F19/00 , G01N33/48 , G01N33/50
CPC分类号： G16B5/00 , G16B20/00 , G16B45/00 , G16B50/00
摘要： Provided is a method for conceptualizing protein interaction networks. The method conceptualizes and simplifies complicated and enormous protein interaction networks wherein the method comprises the steps of (a) conceptualizing protein nodes that form the protein interaction network as gene ontology concepts to reconfigure the network; (b) integrating nodes including the same concepts in the reconfigured network into one node to generate the network by means of exact match; and (c) integrating several nodes having similar concepts in the generated network into one node to reconfigure the generated network by means of approximate match.
摘要翻译：提供了一种用于概念化蛋白质相互作用网络的方法。该方法概念化并简化了复杂和巨大的蛋白质相互作用网络，其中该方法包括以下步骤：（a）将构成蛋白质相互作用网络的蛋白质节点概念化为基因本体概念以重新配置网络; （b）将包括相同概念的节点在重新配置的网络中集成到一个节点中，以通过精确匹配来生成网络; 以及（c）将具有类似概念的几个节点集成到一个节点中，以通过近似匹配来重构所生成的网络。

5. 发明申请

US20080023691A1 Light emitting diode having vertical topology and method of making the same 有权
标题翻译：具有垂直拓扑的发光二极管及其制造方法
公开(公告)号：US20080023691A1
公开(公告)日：2008-01-31
申请号：US11898368
申请日：2007-09-11
申请人： Jun Jang , Jae Choi , Duk Bae , Hyun Cho , Jong Park , Sun Kim , Jeong Lee
发明人： Jun Jang , Jae Choi , Duk Bae , Hyun Cho , Jong Park , Sun Kim , Jeong Lee
IPC分类号： H01L33/00
CPC分类号： H01L33/405 , H01L33/0075 , H01L33/0079 , H01L33/04 , H01L33/06 , H01L33/20 , H01L33/22 , H01L33/32 , H01L33/38 , H01L33/40 , H01L33/44 , H01L2933/0016 , H01L2933/0083
摘要： An LED having vertical topology and a method of making the same is capable of improving a luminous efficiency and reliability, and is also capable of achieving mass productivity. The method includes forming a semiconductor layer on a substrate; forming a first electrode on the semiconductor layer; forming a supporting layer on the first electrode; generating an acoustic stress wave at the interface between the substrate and semiconductor layer, thereby separating the substrate from the semiconductor layer; and forming a second electrode on the semiconductor layer exposed by the separation of the substrate.
摘要翻译：具有垂直拓扑结构的LED及其制造方法能够提高发光效率和可靠性，并且还能够实现批量生产。该方法包括在衬底上形成半导体层; 在所述半导体层上形成第一电极; 在所述第一电极上形成支撑层; 在衬底和半导体层之间的界面处产生声应力波，从而将衬底与半导体层分离; 以及在通过所述衬底的分离而暴露的所述半导体层上形成第二电极。

6. 发明授权

US08007288B2 Apparatus for connecting a multi-conductor cable to a pin grid array connector 有权
标题翻译：用于将多芯电缆连接到针格阵列连接器的装置
公开(公告)号：US08007288B2
公开(公告)日：2011-08-30
申请号：US12566923
申请日：2009-09-25
申请人： Kelley E. Yetter , Anand Desai , John Pyle , Jae Choi
发明人： Kelley E. Yetter , Anand Desai , John Pyle , Jae Choi
IPC分类号： H01R12/00
CPC分类号： H01R31/06 , G01N29/262 , G01R1/0416 , H01R12/7082 , H01R12/712 , H01R2201/20 , H05K1/144 , H05K2201/10189 , H05K2201/10325 , H05K2201/10356 , H05K2201/10378
摘要： An apparatus for connecting a multi-conductor cable of a first device to a pin grid array connector of a second device, wherein said apparatus comprises a first printed circuit board (PCB) for terminating the conductors of the cable, which are connected to a first PCB surface mounted connector mounted on the first PCB. The first PCB surface mounted connector is mated with a second PCB surface mounted connector mounted on a second PCB, on which a PCB surface mounted socket grid array is also mounted for mating to the pin grid array connector of the second device. This apparatus allows the same (i.e., standardized) multi-conductor cable with the same first PCB and the same first PCB surface mounted connector to be used regardless of what style connector is used by the second device.
摘要翻译：一种用于将第一装置的多导体电缆连接到第二装置的针阵列连接器的装置，其中所述装置包括用于端接所述电缆的导体的第一印刷电路板（PCB），所述第一印刷电路板连接到第一装置 PCB表面安装连接器安装在第一个PCB上。第一PCB表面安装连接器与安装在第二PCB上的第二PCB表面安装连接器配合，其上还安装有PCB表面安装的插座格栅阵列，用于配合到第二设备的引脚格栅阵列连接器。该装置允许使用具有相同的第一PCB和相同的第一PCB表面安装的连接器的相同（即标准化）多导体电缆，而不管第二装置使用什么样的连接器。

7. 发明授权

US07845849B1 Testing BGA solder joints by localized pulsed-heat thermography 有权
标题翻译：通过局部脉冲热热成像测试BGA焊点
公开(公告)号：US07845849B1
公开(公告)日：2010-12-07
申请号：US12103389
申请日：2008-04-15
申请人： Jae Choi , Mark Woolley
发明人： Jae Choi , Mark Woolley
IPC分类号： G01K1/00 , G01N25/00
CPC分类号： G01R31/048 , G01N25/72 , G01R31/304
摘要： A pulse of heat or cold is applied and conducted transversely through a ball grid array device and a printed circuit board via a selected one of the solder joints between them. Heat diffused through the other solder joints is neutralized by a thermal bias shield. The shield is then removed and a thermographic image of the printed circuit board is taken. The process is repeated for each solder joint, and the images are compared to identify defective solder joints.
摘要翻译：施加热或冷的脉冲并通过球栅阵列器件和印刷电路板通过它们之间的所选焊接点之一横向地传导。通过其他焊点扩散的热被热偏置屏蔽中和。然后取下屏蔽层，并拍摄印刷电路板的热成像图像。对每个焊点重复该过程，并比较图像以识别有缺陷的焊点。

8. 发明申请

US20070295494A1 Flat Type Heat Transferring Device and Manufacturing Method of the Same 审中-公开
标题翻译：平板式传热装置及其制造方法
公开(公告)号：US20070295494A1
公开(公告)日：2007-12-27
申请号：US11768689
申请日：2007-06-26
申请人： George Mayer , Jae Choi , Ki Nam
发明人： George Mayer , Jae Choi , Ki Nam
IPC分类号： F28F3/12
CPC分类号： F28D15/0233 , F28D15/046 , Y10T29/49353
摘要： The present invention relates to a flat type heat transferring device, and manufacturing method of the same, which is comprises of a capillary wick that is provided inside a case and formed by weaving a wire in the horizontal direction and the vertical direction so as to absorb a liquid coolant, and a linear member that is formed to have a different wire diameter from the wire of the capillary wick and woven in the capillary wick to form a space where a vapor coolant flows. Accordingly, the mechanically stabilized support rigidity can be secured and an ultra thin configuration can be implemented with a light-weight, in particular, the problem of degrading the capillary force is resolved, and it has the effect that the cooling efficiency can be improved with smooth flowing of a coolant.
摘要翻译：扁平型传热装置及其制造方法技术领域本发明涉及一种扁平型传热装置及其制造方法，其特征在于，包括：设置在壳体内部并通过在水平方向和垂直方向上编织电线形成的毛细管芯，以吸收液体冷却剂和线性构件，其被形成为具有与毛细管芯的线不同的线直径并且在毛细管芯中织造以形成蒸气冷却剂流动的空间。因此，可以确保机械稳定的支撑刚度，并且可以以轻的重量实现超薄结构，特别是解决了降低毛细管力的问题，并且具有可以通过以下方式改善冷却效率：冷却液流畅。

9. 发明申请

US20070141082A1 Cell surface expression vector of parvovirus antigen and microorganisms transformed thereof 审中-公开
标题翻译：细小病毒抗原的细胞表面表达载体及其转化的微生物
公开(公告)号：US20070141082A1
公开(公告)日：2007-06-21
申请号：US10588359
申请日：2005-02-04
申请人： Moon-Hee Sung , Chul Kim , Chang Jung , Seung Hong , Jong Lee , Jae Choi , Motomitsu Sewaki , Jong Kim
发明人： Moon-Hee Sung , Chul Kim , Chang Jung , Seung Hong , Jong Lee , Jae Choi , Motomitsu Sewaki , Jong Kim
IPC分类号： A61K39/155 , C12N15/74 , C12N1/21
CPC分类号： C07K14/005 , C12N15/74 , C12N2750/14322
摘要： The present invention relates to a surface expression vector expressing a parvovirus antigen on the surface of microorganisms, the vector containing not only a gene encoding the capsid antigen protein of parvovirus causing canine parvovirus (CPV) infection and feline panleukopenia (FLP) but also at least one of pgsB, pgsC and pgsA genes encoding a poly-gamma-glutamate synthetase complex. Also, the present invention relates to microorganisms transformed with the surface expression vector, and parvovirus vaccines containing the transformed microorganisms. According to the present invention, the use of the recombinant bacterial strains expressing the parvovirus antigen on their surface allows the economical production of vaccines for the treatment and prevention of canine parvovirus infection and feline panleukopenia.
摘要翻译：本发明涉及表达微生物表面细小病毒抗原的表面表达载体，该载体不仅包含编码引起犬细小病毒（CPV）感染和猫泛白细胞减少症（FLP）的细小病毒的衣壳抗原蛋白的基因，而且至少编码聚-γ-谷氨酸合成酶复合物的pgsB，pgsC和pgsA基因之一。此外，本发明涉及用表面表达载体转化的微生物，以及含有转化的微生物的细小病毒疫苗。根据本发明，在其表面上使用表达细小病毒抗原的重组细菌菌株可以经济地生产用于治疗和预防犬细小病毒感染和猫泛白细胞减少症的疫苗。

10. 发明申请

US20070136033A1 Method for designing insulation thickness of 22.9kV class High-temperature superconducting cable using conversion coefficient 审中-公开
标题翻译： 22.9kV级绝缘厚度的设计方法使用转换系数的高温超导电缆
公开(公告)号：US20070136033A1
公开(公告)日：2007-06-14
申请号：US11338352
申请日：2006-01-24
申请人： Sang Kim , Dong Kwag , Hyeon Cheon , Jae Choi
发明人： Sang Kim , Dong Kwag , Hyeon Cheon , Jae Choi
IPC分类号： G06F17/10
CPC分类号： G06F17/50 , G06F2217/36 , G06F2217/78 , G06F2217/80 , H01B3/008
摘要： Disclosed herein is a method for designing an insulation thickness of a 22.9 kV high-temperature superconducting cable wherein conversion coefficients for use in the transmission of electric power. In the insulation thickness designing method, differently from a conventional design method wherein only AC insulation breakdown electric-field, impulse insulation breakdown electric-field, and partial discharge initiation electric-field characteristics of an insulation sheet sample are applied to cable insulation thickness design equations, conversion coefficients, which are obtained in consideration of the effects of shape, area, and thickness along with the respective electric-field values, to the cable insulation thickness design equations, thereby achieving an increase in the accuracy of the insulation thickness of the high-temperature superconducting cable to be manufactured.
摘要翻译：本文公开了一种用于设计用于电力传输的转换系数的22.9kV高温超导电缆的绝缘厚度的方法。在绝缘厚度设计方法中，与绝缘层样品的绝缘击穿电场，脉冲绝缘击穿电场和局部放电起始电场特性的传统设计方法不同的是，应用于电缆绝缘厚度设计方程式，考虑到形状，面积和厚度以及各自的电场值对电缆绝缘厚度设计方程的影响而获得的转换系数，从而实现了高的绝缘厚度的精度的提高要制造的超导电缆。

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