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1. 发明申请

US20080221660A1 Platelet Gel for Treatment of Aneurysms 审中-公开
标题翻译：用于治疗动脉瘤的血小板凝胶
公开(公告)号：US20080221660A1
公开(公告)日：2008-09-11
申请号：US12045909
申请日：2008-03-11
申请人： Jack Chu , Jonathan Morris , Josiah Wilcox , Brian Fernandes
发明人： Jack Chu , Jonathan Morris , Josiah Wilcox , Brian Fernandes
IPC分类号： A61F2/82
CPC分类号： A61L27/3641 , A61L27/3616 , A61L27/3645 , A61L27/507 , A61L27/54 , A61L2300/406 , A61L2300/414 , A61L2300/43 , A61L2300/434
摘要： Methods for ameliorating stent graft migration and endoleak using treatment site-specific platelet gel compositions in combination with stent grafts are disclosed. Also disclosed are platelet gel compositions directly to treatment sites before, during or after stent graft implantation. Additional embodiments include medical devices having platelet gel coatings and/or platelet gel delivery devices useful for treating aneurysms.
摘要翻译：公开了使用处理部位特异性血小板凝胶组合物与支架移植物组合来改善支架移植物迁移和内漏的方法。还公开了在支架移植物植入之前，期间或之后直接用于治疗部位的血小板凝胶组合物。另外的实施方案包括具有用于治疗动脉瘤的血小板凝胶涂层和/或血小板凝胶递送装置的医疗装置。

2. 发明申请

US20060136050A1 Autologous Growth Factors to Promote Tissue In-Growth in Vascular Device 审中-公开
标题翻译：自体生长因子促进组织生长在血管装置中
公开(公告)号：US20060136050A1
公开(公告)日：2006-06-22
申请号：US11276518
申请日：2006-03-03
申请人： Jack Chu , Scott Doig , Brian Fernandes , Trevor Huang , Josiah Wilcox
发明人： Jack Chu , Scott Doig , Brian Fernandes , Trevor Huang , Josiah Wilcox
IPC分类号： A61F2/06
CPC分类号： A61L27/3616 , A61L27/3641 , A61L27/3645 , A61L27/54 , A61L2300/414
摘要： Methods and devices for ameliorating stent graft migration and endoleak using treatment site-specific cell growth promoting compositions in combination with stent grafts are disclosed. Also disclosed is coating of autologous growth factor compositions onto stent grafts prior to stent graft implantation. Additional embodiments include stent grafts having autologous growth factor composition coatings useful for treating aneurysms.
摘要翻译：公开了使用处理位点特异性细胞生长促进组合物与支架移植物组合来改善支架移植物迁移和内漏的方法和装置。还公开了在支架移植物植入之前将自体生长因子组合物涂覆到覆膜支架上。另外的实施方案包括具有用于治疗动脉瘤的自体生长因子组合物涂层的支架移植物。

3. 发明授权

US07727199B2 Methods and devices to deliver injected agents to an aneurysm site 有权
标题翻译：将注射剂递送到动脉瘤部位的方法和装置
公开(公告)号：US07727199B2
公开(公告)日：2010-06-01
申请号：US11276517
申请日：2006-03-03
申请人： Brian Fernandes , Jack Chu
发明人： Brian Fernandes , Jack Chu
IPC分类号： A61M5/178
CPC分类号： A61L27/3616 , A61L27/3641 , A61L27/3645 , A61L27/54 , A61L2300/414
摘要： Method and devices to administer a bioactive material within a vessel while maintaining nearly-constant pressure within the vessel are disclosed. In one embodiment the methods and devices include a multi-lumen catheter to administer bioactive materials and simultaneously drain or evacuate excess fluid or bio-inactive materials at an aneurysm site within a vessel.
摘要翻译：公开了在容器内施用生物活性物质同时保持容器内几乎恒定的压力的方法和装置。在一个实施方案中，所述方法和装置包括多腔导管，用于施用生物活性材料并同时在容器内的动脉瘤部位排出或排出多余的流体或生物惰性材料。

4. 发明授权

US07387645B2 Cellular therapy to heal vascular tissue 有权
标题翻译：细胞疗法治愈血管组织
公开(公告)号：US07387645B2
公开(公告)日：2008-06-17
申请号：US10423193
申请日：2003-04-25
申请人： Brian Fernandes , Jack Chu , Prema Ganesan
发明人： Brian Fernandes , Jack Chu , Prema Ganesan
IPC分类号： A61F2/02 , A01N63/00 , A61K48/00
CPC分类号： A61F2/07 , A61F2002/065 , A61F2002/077
摘要： The present invention encompasses methods and apparatus for minimizing the risks inherent in endovascular grafting for blood vessel therapy and repair. The invention involves delivering adult stem cells, embryonic stem cells, progenitor cells, fibroblasts, or smooth muscle cells to the diseased blood vessel.
摘要翻译：本发明包括用于最小化用于血管治疗和修复的血管内移植中固有的风险的方法和装置。本发明涉及将成体干细胞，胚胎干细胞，祖细胞，成纤维细胞或平滑肌细胞递送至患病血管。

5. 发明申请

US20060135942A1 Methods and Devices to Deliver Injected Agents to an Aneurysm Site 有权
标题翻译：将注射剂递送到动脉瘤部位的方法和装置
公开(公告)号：US20060135942A1
公开(公告)日：2006-06-22
申请号：US11276517
申请日：2006-03-03
申请人： Brian Fernandes , Jack Chu
发明人： Brian Fernandes , Jack Chu
IPC分类号： A61M31/00
CPC分类号： A61L27/3616 , A61L27/3641 , A61L27/3645 , A61L27/54 , A61L2300/414
摘要： Method and devices to administer a bioactive material within a vessel while maintaining nearly-constant pressure within the vessel are disclosed. In one embodiment the methods and devices include a multi-lumen catheter to administer bioactive materials and simultaneously drain or evacuate excess fluid or bio-inactive materials at an aneurysm site within a vessel.
摘要翻译：公开了在容器内施用生物活性物质同时保持容器内几乎恒定的压力的方法和装置。在一个实施方案中，所述方法和装置包括多腔导管，用于施用生物活性材料并同时在容器内的动脉瘤部位排出或排出多余的流体或生物惰性材料。

6. 发明申请

US20080187524A1 Cellular Therapy to Heal Vascular Tissue 审中-公开
标题翻译：细胞疗法治愈血管组织
公开(公告)号：US20080187524A1
公开(公告)日：2008-08-07
申请号：US12062230
申请日：2008-04-03
申请人： Brian Fernandes , Jack Chu , Prema Ganesan
发明人： Brian Fernandes , Jack Chu , Prema Ganesan
IPC分类号： A61K35/12 , A61P7/00
CPC分类号： A61F2/07 , A61F2002/065 , A61F2002/077
摘要： The present invention encompasses methods and apparatus for minimizing the risks inherent in endovascular grafting for blood vessel therapy and repair. The invention involves delivering adult stem cells, embryonic stem cells, progenitor cells, fibroblasts, or smooth muscle cells to the diseased blood vessel.
摘要翻译：本发明包括用于最小化用于血管治疗和修复的血管内移植中固有的风险的方法和装置。本发明涉及将成体干细胞，胚胎干细胞，祖细胞，成纤维细胞或平滑肌细胞递送至患病血管。

7. 发明申请

US20060095121A1 Autologous platelet gel on a stent graft 审中-公开
标题翻译：支架移植物上的自体血小板凝胶
公开(公告)号：US20060095121A1
公开(公告)日：2006-05-04
申请号：US10977545
申请日：2004-10-28
申请人： Brian Fernandes , Jack Chu
发明人： Brian Fernandes , Jack Chu
IPC分类号： A61F2/06
CPC分类号： A61L27/3616 , A61L27/3641 , A61L27/3645 , A61L27/54 , A61L2300/414
摘要： Methods for ameliorating stent graft migration and endoleak using treatment site-specific cell growth promoting compositions in combination with stent grafts are disclosed. Also disclosed are application of cell growth promoting compositions such as, but not limited to, autologous platelet gel compositions directly to treatment sites before, during or after stent graft implantation. Additional embodiments include medical devices having autologous platelet gel coatings and/or autologous platelet gel delivery devices useful for treating aneurysms.
摘要翻译：公开了使用处理部位特异性细胞生长促进组合物与支架移植物组合来改善支架移植物迁移和内漏的方法。还公开了将细胞生长促进组合物（例如但不限于自体血小板凝胶组合物）直接施用于支架移植物植入之前，期间或之后的治疗部位。另外的实施方案包括具有自体血小板凝胶涂层和/或可用于治疗动脉瘤的自体血小板凝胶递送装置的医疗装置。

8. 发明申请

US20140188665A1 CrowdChunk System, Method, and Computer Program Product for Searching Summaries of Online Reviews of Products 审中-公开
标题翻译： CrowdChunk系统，方法和计算机程序产品，用于搜索产品在线评论摘要
公开(公告)号：US20140188665A1
公开(公告)日：2014-07-03
申请号：US14058263
申请日：2013-10-20
申请人： Douglas Dane Baker , Brian Fernandes , Paulo Malvar Fernandez
发明人： Douglas Dane Baker , Brian Fernandes , Paulo Malvar Fernandez
IPC分类号： G06Q30/06
CPC分类号： G06Q30/0625
摘要： System, method, and computer program product for researching reviews written online to assess the performance and functionality of digital media consumer products bought online or not (e.g. eBooks, movies, TV shows, music, DVD's, etc.). The system extracts reviews from multiple online sources comprising: online “stores”, professional articles, blogs, online magazines, websites, etc.; and, utilizes sentiment analysis algorithms and supervised machine learning analysis to present more informative summaries for each product's reviews, comprising: a sentence that encapsulates a sentiment held by many users; the most positive and negative comments; and a list of features with average scores (e.g. performance, price, etc.). Additionally, the user may view a separate review detail page per product that provides further summaries, such as a short list of other products that the same reviewer gave a very positive review for the features. The user is then able to purchase the product via a link.
摘要翻译：系统，方法和计算机程序产品，用于研究在线评估在线购买或不在线购买的数字媒体消费产品的性能和功能（例如电子书，电影，电视节目，音乐，DVD等）。该系统从多个在线来源提取评论，包括：在线“商店”，专业文章，博客，在线杂志，网站等; 并利用情感分析算法和监督机器学习分析，为每个产品的评论提供更多的内容丰富的摘要，包括：一个封闭许多用户持有的情绪的句子; 最积极和消极的意见; 以及具有平均分数（例如性能，价格等）的功能列表。此外，用户可以查看每个产品的单独的评论详细信息页面，该页面提供更多的摘要，例如同一评审者对功能进行非常积极的评价的其他产品的简短列表。然后用户可以通过链接购买产品。

9. 发明申请

US20120311387A1 METHOD AND APPARATUS FOR LOAD TESTING ONLINE SERVER SYSTEMS 有权
标题翻译：用于负载测试在线服务器系统的方法和设备
公开(公告)号：US20120311387A1
公开(公告)日：2012-12-06
申请号：US13153271
申请日：2011-06-03
申请人： Sreelata Santhosh , Mark Vaden , Brian Fernandes
发明人： Sreelata Santhosh , Mark Vaden , Brian Fernandes
IPC分类号： G06F11/00
CPC分类号： G06F11/3433 , G06F11/3414
摘要： A method includes capturing data that is representative of actions performed by each of a plurality of human user operated clients as they interact with an online software application, loading at least one or more portions of the captured data into one or more automated simulation clients, and using the one or more automated simulation clients to perform load testing of an online server system. A system includes a data capturing stage, one or more automated simulation clients, and a configuration stage. A computer readable storage medium stores one or more computer programs that will cause a processor based system to execute steps including receiving data that was captured during a running of an online software application and that is representative of actions performed by each of a plurality of human user operated clients as they interacted with the online software application, and loading at least one or more portions of the data into one or more automated simulation clients that are configured to perform load testing of an online server system.
摘要翻译：一种方法包括捕获表示由多个人类用户操作的客户端中的每一个在与在线软件应用程序交互时执行的动作的数据，将捕获的数据的至少一个或多个部分加载到一个或多个自动化仿真客户机中，以及使用一个或多个自动化模拟客户端来执行在线服务器系统的负载测试。系统包括数据捕获阶段，一个或多个自动仿真客户端和配置阶段。计算机可读存储介质存储一个或多个计算机程序，其将使基于处理器的系统执行包括接收在线软件应用程序运行期间捕获的数据的步骤，并且其代表由多个人类用户中的每一个执行的动作它们与在线软件应用程序进行交互，并将至少一个或多个数据部分加载到被配置为执行在线服务器系统的负载测试的一个或多个自动仿真客户机中。

10. 发明申请

US20100279767A1 Method for Ladder Ranking in a Game 有权
标题翻译：游戏中梯子排名的方法
公开(公告)号：US20100279767A1
公开(公告)日：2010-11-04
申请号：US12839311
申请日：2010-07-19
申请人： Shekhar V. Dhupelia , Glen Van Datta , Brian Fernandes , Eiko Erika Kato , William McCarroll
发明人： Shekhar V. Dhupelia , Glen Van Datta , Brian Fernandes , Eiko Erika Kato , William McCarroll
IPC分类号： A63F9/24
CPC分类号： A63F13/352 , A63F13/12 , A63F13/335 , A63F13/358 , A63F13/71 , A63F2300/401 , A63F2300/407 , A63F2300/50 , A63F2300/513 , A63F2300/532 , A63F2300/534 , A63F2300/5546 , G06Q10/025 , G06Q20/108 , G06Q40/123 , H04L67/1002 , H04L67/1012 , H04L67/1014 , H04L67/38 , Y10S707/99931 , Y10S707/99936
摘要： Methods for creating an interactive gaming environment are provided. In various embodiments, methods of the present invention may include initializing an interactive game application at a game server which is then characterized as having an active status, notifying a lobby server concerning the active status of the game server, registering the application with a universe management server via the lobby server, and allowing users to join the interactive gaming environment. The users joining the interactive gaming environment may be identified by a server key obtained from the game server.
摘要翻译：提供了创建交互式游戏环境的方法。在各种实施例中，本发明的方法可以包括在游戏服务器上初始化交互式游戏应用程序，该游戏服务器的特征在于具有活动状态，通知大厅服务器关于游戏服务器的活动状态，将应用程序注册到宇宙管理服务器，并允许用户加入交互式游戏环境。可以通过从游戏服务器获得的服务器密钥来识别加入交互式游戏环境的用户。

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