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1. 发明申请

US20100256726A1 Braided Flange Branch Graft for Branch Vessel 有权
标题翻译：用于分支船的编织法兰分支移植
公开(公告)号：US20100256726A1
公开(公告)日：2010-10-07
申请号：US12816115
申请日：2010-06-15
申请人： David Erickson , Nasser Rafiee , Nareak Douk , Jonathan Morris , Curtis Hanson , Matthew Rust , Sonny Yamasaki , Prema Ganesan
发明人： David Erickson , Nasser Rafiee , Nareak Douk , Jonathan Morris , Curtis Hanson , Matthew Rust , Sonny Yamasaki , Prema Ganesan
IPC分类号： A61F2/84
CPC分类号： A61F2/064 , A61F2/07 , A61F2/90 , A61F2002/061 , A61F2002/821 , A61F2250/0039 , D04C1/06 , D10B2509/06
摘要： A braided flange branch graft formed of a braided super elastic memory material includes a neck between an inner flange and an outer flange. The neck is positioned in a side opening in a sidewall of a main stent graft and the inner flange and outer flange are deployed on opposite sides of the sidewall. The inner flange and the outer flange have a diameter greater than a diameter of the side opening in the sidewall of the main stent graft. Thus, the sidewall of the main stent graft is sandwiched between the inner flange and the outer flange securely and simply mounting the braided flange branch graft to the main stent graft. The braided flange has a substantially unobstructed fluid communication passage therethrough. Further, when stretched into a substantially cylindrical shape for delivery, the braided flange branch graft has a small delivery profile and is extremely flexible.
摘要翻译：由编织超弹性记忆材料形成的编织法兰分支移植物包括在内凸缘和外凸缘之间的颈部。颈部位于主支架移植物的侧壁中的侧开口中，并且内凸缘和外凸缘部署在侧壁的相对侧上。内凸缘和外凸缘的直径大于主支架移植物的侧壁中的侧开口的直径。因此，主支架移植物的侧壁被夹在内凸缘和外凸缘之间，并且将编织法兰分支移植物简单地安装到主支架移植物上。编织法兰具有通过其的基本上无障碍的流体连通通道。此外，当拉伸成基本上圆柱形以用于输送时，编织法兰分支移植物具有小的输送轮廓并且非常灵活。

2. 发明申请

US20080187524A1 Cellular Therapy to Heal Vascular Tissue 审中-公开
标题翻译：细胞疗法治愈血管组织
公开(公告)号：US20080187524A1
公开(公告)日：2008-08-07
申请号：US12062230
申请日：2008-04-03
申请人： Brian Fernandes , Jack Chu , Prema Ganesan
发明人： Brian Fernandes , Jack Chu , Prema Ganesan
IPC分类号： A61K35/12 , A61P7/00
CPC分类号： A61F2/07 , A61F2002/065 , A61F2002/077
摘要： The present invention encompasses methods and apparatus for minimizing the risks inherent in endovascular grafting for blood vessel therapy and repair. The invention involves delivering adult stem cells, embryonic stem cells, progenitor cells, fibroblasts, or smooth muscle cells to the diseased blood vessel.
摘要翻译：本发明包括用于最小化用于血管治疗和修复的血管内移植中固有的风险的方法和装置。本发明涉及将成体干细胞，胚胎干细胞，祖细胞，成纤维细胞或平滑肌细胞递送至患病血管。

3. 发明申请

US20060247760A1 Methods and apparatus for treatment of aneurysms adjacent branch arteries 审中-公开
标题翻译：用于治疗相邻分支动脉的动脉瘤的方法和装置
公开(公告)号：US20060247760A1
公开(公告)日：2006-11-02
申请号：US11117978
申请日：2005-04-29
申请人： Prema Ganesan , Jonathan Morris , David Erickson , Matthew Rust , Curtis Hanson , Jack Chu , Charles Thomas
发明人： Prema Ganesan , Jonathan Morris , David Erickson , Matthew Rust , Curtis Hanson , Jack Chu , Charles Thomas
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/061 , A61F2002/075 , A61F2220/005 , A61F2220/0075
摘要： A polymer coating/ring is employed to aid in the sealing and connection of modular elements used in body flow lumens for the exclusion and bypass of diseased regions of the flow lumen, such as where aneurysm occurs adjacent to branching blood vessels.
摘要翻译：使用聚合物涂层/环来帮助用于身体流动腔中的模块化元件的密封和连接，用于流动腔的患病区域的排除和旁路，例如在分支血管附近发生动脉瘤的地方。

4. 发明授权

US07371228B2 Delivery of therapeutics to treat aneurysms 有权
标题翻译：交付治疗动脉瘤治疗
公开(公告)号：US07371228B2
公开(公告)日：2008-05-13
申请号：US10665936
申请日：2003-09-19
申请人： Jack Chu , Dave Erickson , Prema Ganesan , Jonathan Morris
发明人： Jack Chu , Dave Erickson , Prema Ganesan , Jonathan Morris
IPC分类号： A61K9/22 , A61F13/00 , A61M31/00
CPC分类号： A61L31/16 , A61B2017/00778 , A61F2/07 , A61F2/90 , A61F2002/065 , A61F2002/077 , A61F2250/0067 , A61L2300/00 , A61L2430/36
摘要： A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a reservoir and delivery means in a localized, and, in some embodiments, time-released regimen, to treat, limit and reduce the severity of the aneurysm.
摘要翻译：提供了一种治疗动脉瘤的方法和装置。不同的治疗剂通过储存器和递送装置在局部的，在一些实施方案中被递送到治疗，限制和降低动脉瘤的严重性的方式递送到动脉瘤部位。

5. 发明申请

US20070239252A1 A Mechanism to Ensure Placement of Ostial Renal Stents 审中-公开
标题翻译：确保置入肾支架的机制
公开(公告)号：US20070239252A1
公开(公告)日：2007-10-11
申请号：US11279206
申请日：2006-04-10
申请人： Darren Hopkins , Jack Chu , Jonathan Morris , James Machek , Prema Ganesan , Matthew Rust , Trevor Greenan , James Moriarty
发明人： Darren Hopkins , Jack Chu , Jonathan Morris , James Machek , Prema Ganesan , Matthew Rust , Trevor Greenan , James Moriarty
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2002/821 , A61F2250/0039
摘要： A method of using a delivery system includes advancing a stent to be located within an ostium of a vessel; advancing a basket actuation button of a handle to deploy a basket of the basket assembly; moving the basket into engagement with a parent vessel, the basket having a larger diameter than a diameter of the ostium; deploying the stent within an ostial lesion of the vessel; and contracting the basket.
摘要翻译：使用输送系统的方法包括推进位于血管口内的支架; 推动手柄的篮子致动按钮以部署一篮篮组件; 将篮子移动到与父母船只接合，篮子具有比口的直径更大的直径; 将支架部署在血管的口腔损伤中; 并承包篮子。

6. 发明申请

US20070203565A1 Method for Endovascular Bypass Stent Graft Delivery 有权
标题翻译：血管旁路支架移植方法
公开(公告)号：US20070203565A1
公开(公告)日：2007-08-30
申请号：US11464036
申请日：2006-08-11
申请人： Matthew Rust , Prema Ganesan , Curtis Hanson , Jack Chu
发明人： Matthew Rust , Prema Ganesan , Curtis Hanson , Jack Chu
IPC分类号： A61F2/06 , A61F2/94
CPC分类号： A61F2/07 , A61B17/12022 , A61B17/12109 , A61B17/12118 , A61B17/12131 , A61B17/3403 , A61B2017/00252 , A61F2/06 , A61F2/064 , A61F2/89 , A61F2002/061 , A61F2002/072
摘要： The invention provides a method of providing an endovascular bypass. The method includes the steps of inserting an elastic needle carrying a guidewire adjacent an ostium via a catheter and extending the needle through a branch vessel wall. The method continues by extending the needle through the extravascular space and inserting the needle through a main vessel wall to create an opening. The needle is retracted, leaving the guidewire in place. A bypass stent graft is inserted along the guidewire to provide a pathway between the branch vessel and the main vessel, and the inserted bypass stent graft is expanded. The branch vessel is occluded between the ostium of the bypass stent graft and the main vessel, and a main stent graft is inserted in the main vessel proximate the opening in the main vessel wall.
摘要翻译：本发明提供一种提供血管内旁路的方法。该方法包括以下步骤：通过导管将携带导丝的弹性针插入口附近，并将针延伸穿过分支血管壁。该方法通过将针穿过血管外空间并将针插入主血管壁以创建开口来继续。针缩回，将导丝留在原位。沿着导丝插入旁路支架移植物以提供分支血管和主血管之间的通路，并且插入的旁路支架移植物扩张。分支血管被封闭在旁路支架移植物的口和主血管之间，并且主支架移植物在主血管壁中的开口附近插入主血管。

7. 发明申请

US20050278013A1 Method for endovascular bypass stent graft delivery 审中-公开
标题翻译：血管内旁路支架移植物输送方法
公开(公告)号：US20050278013A1
公开(公告)日：2005-12-15
申请号：US10891397
申请日：2004-07-14
申请人： Matthew Rust , Prema Ganesan , Curtis Hanson , Jack Chu
发明人： Matthew Rust , Prema Ganesan , Curtis Hanson , Jack Chu
IPC分类号： A61B17/00 , A61B17/12 , A61B17/34 , A61F2/02 , A61F2/06
CPC分类号： A61F2/07 , A61B17/12022 , A61B17/12109 , A61B17/12118 , A61B17/12131 , A61B17/3403 , A61B2017/00252 , A61F2/06 , A61F2/064 , A61F2/89 , A61F2002/061 , A61F2002/072
摘要： The invention provides a method of providing an endovascular bypass. The method includes the steps of inserting an elastic needle carrying a guidewire adjacent an ostium via a catheter and extending the needle through a branch vessel wall. The method continues by extending the needle through the extravascular space and inserting the needle through a main vessel wall to create an opening. The needle is retracted, leaving the guidewire in place. A bypass stent graft is inserted along the guidewire to provide a pathway between the branch vessel and the main vessel, and the inserted bypass stent graft is expanded. The branch vessel is occluded between the ostium of the bypass stent graft and the main vessel, and a main stent graft is inserted in the main vessel proximate the opening in the main vessel wall.
摘要翻译：本发明提供一种提供血管内旁路的方法。该方法包括以下步骤：通过导管将携带导丝的弹性针插入口附近，并将针延伸穿过分支血管壁。该方法通过将针穿过血管外空间并将针插入主血管壁以创建开口来继续。针缩回，将导丝留在原位。沿着导丝插入旁路支架移植物以提供分支血管和主血管之间的通路，并且插入的旁路支架移植物扩张。分支血管被封闭在旁路支架移植物的口和主血管之间，并且主支架移植物在主血管壁中的开口附近插入主血管。

8. 发明授权

US10307244B2 Methods and apparatus for treatment of aneurysms adjacent branch arteries 有权
公开(公告)号：US10307244B2
公开(公告)日：2019-06-04
申请号：US13091363
申请日：2011-04-21
申请人： Prema Ganesan , Jonathan Morris , David R. Erickson , Matthew Rust , Curtis Hanson , Jack Chu , Charles Thomas
发明人： Prema Ganesan , Jonathan Morris , David R. Erickson , Matthew Rust , Curtis Hanson , Jack Chu , Charles Thomas
IPC分类号： A61F2/07 , A61F2/06 , A61F2/89 , A61F2/90
摘要： A polymer coating/ring is employed to aid in the sealing and connection of modular elements used in body flow lumens for the exclusion and bypass of diseased regions of the flow lumen, such as where aneurysm occurs adjacent to branching blood vessels.

9. 发明授权

US09636439B2 Delivery of therapeutics to treat aneurysms 有权
公开(公告)号：US09636439B2
公开(公告)日：2017-05-02
申请号：US12062245
申请日：2008-04-03
申请人： Jack Chu , Dave Erickson , Prema Ganesan , Jonathan Morris
发明人： Jack Chu , Dave Erickson , Prema Ganesan , Jonathan Morris
IPC分类号： A61M1/00 , A61L31/16 , A61F2/07 , A61B17/00 , A61F2/06 , A61F2/90
CPC分类号： A61L31/16 , A61B2017/00778 , A61F2/07 , A61F2/90 , A61F2002/065 , A61F2002/077 , A61F2250/0067 , A61L2300/00 , A61L2430/36
摘要： A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a reservoir and delivery means in a localized, and, in some embodiments, time-released regimen, to treat, limit and reduce the severity of the aneurysm.

10. 发明授权

US07955374B2 Modular branch vessel stent-graft assembly 有权
标题翻译：模块化分支血管支架移植组件
公开(公告)号：US07955374B2
公开(公告)日：2011-06-07
申请号：US11219353
申请日：2005-09-02
申请人： David R. Erickson , Prema Ganesan
发明人： David R. Erickson , Prema Ganesan
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/075 , A61F2002/821
摘要： Modular branch vessel stent-graft assemblies for the treatment arterial or vascular disease at the branch of two or more arteries or blood flow passageways, including, for example, abdominal aortic aneurysms are assembled in a patient's trunk/parent artery, from at least two components; a first component and a second component. The first and second components each include a first and second window, or fenestration. The second component couples with the first component by fitting at least partially in the first component to form the modular branch vessel stent-graft assembly with two selectively locatable branch openings. As the first and second components are deployed, the second component is selectively position able relative to first component so that the first and second component first and second windows overlap to form two branch openings whose longitudinal and angular positions are selectable within a range.
摘要翻译：用于治疗在两个或更多个动脉或血液通道（包括例如腹主动脉瘤）的分支处的动脉或血管疾病的模块化分支血管支架 - 移植组件被组装在患者的躯干/父动脉中，至少两个组分 ; 第一组件和第二组件。第一和第二部件各自包括第一和第二窗口或开窗。第二部件通过至少部分地配合在第一部件中而与第一部件相连，以形成具有两个可选择定位的分支开口的模块化分支血管支架移植物组件。当第一和第二部件被部署时，第二部件相对于第一部件选择性地定位，使得第一和第二部件第一和第二窗口重叠以形成两个分支开口，其纵向和角度位置可在一个范围内选择。

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