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    • 2. 发明申请
    • COMPOSITION CONTAINING 4-O-METHYLHONOKIOL FOR TREATING OR PREVENTING AMYLOID- RELATED DISEASES
    • 含有4-O-甲基羟基木酚醇的组合物用于治疗或预防淀粉样蛋白相关性疾病
    • WO2010036052A3
    • 2010-07-22
    • PCT/KR2009005485
    • 2009-09-25
    • BIOLAND LTDKIM KI HOKIM KI SOOKIM YOUNG HEUIKIM JIN GUKKIM KYOUNG TAEHAN CHANG SUNGLEE SANG IL
    • KIM KI HOKIM KI SOOKIM YOUNG HEUIKIM JIN GUKKIM KYOUNG TAEHAN CHANG SUNGLEE SANG IL
    • A61K31/085A23L1/29A23L1/30A61K31/05A61P25/28
    • A61K31/085A23L2/52A23L33/105A61K31/05A61K36/575
    • The present invention relates to a composition for treating or preventing amyloid-related diseases, said composition containing 4-O-methylhonokiol as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition which contains as an active ingredient and which is useful in treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorders, memory impairment, amyloidosis, etc. The inventors of the present invention first found that 4-O-methylhonokiol of the present invention inhibits the formation of beta-amyloid, and it is evidenced that 4-O-methylhonokiol can be used in the treatment and prevention of amyloid-related diseases. The inventors of the present invention have performed animal tests such as a water maze test, a passive avoidance test, and the like using experimental rats to find that 4-O-methylhonokiol is effective in the treatment or prevention of amyloid-related diseases such as Alzheimer's disease, cognitive disorders, memory impairment, amyloidosis, etc. The inventors of the prevent invention further have performed an acetylcholinesterase activity inhibition test using the cortex and hippocampus of the brain of a rat to find that 4-O-methylhonokiol is significantly effective in the treatment or prevention of Alzheimer's disease specifically from among the amyloid-related diseases.
    • 本发明涉及用于治疗或预防淀粉样蛋白相关疾病的组合物,所述组合物含有4-O-甲基和厚朴酚作为活性成分。 更具体地说,本发明涉及含有作为活性成分并可用于治疗或预防淀粉样蛋白相关疾病如阿尔茨海默病,认知障碍,记忆障碍,淀粉样变性等的药物组合物。本发明的发明人 首先发现本发明的4-O-甲基和厚朴酚抑制β-淀粉样蛋白的形成,并且证明4-O-甲基和厚朴酚可用于治疗和预防淀粉样蛋白相关疾病。 本发明的发明人使用实验大鼠进行了水迷宫试验,被动回避试验等动物试验,结果发现4-O-甲基和厚朴酚有效治疗或预防淀粉样蛋白相关疾病,例如 阿尔茨海默病,认知障碍,记忆障碍,淀粉样变性等。本发明的发明人进一步使用大鼠脑的皮质和海马进行了乙酰胆碱酯酶活性抑制试验,发现4-O-甲基和厚朴酚在 特别是从淀粉样蛋白相关疾病中治疗或预防阿尔茨海默病。
    • 6. 发明授权
    • Decoration having integrally formed image code and method for manufacturing the same
    • 具有整体形成图像编码的装饰及其制造方法
    • KR101194680B1
    • 2012-10-29
    • KR20120031954
    • 2012-03-28
    • KIM KYOUNG TAE
    • KIM KYOUNG TAE
    • B44C1/24B44C1/22B44C3/00
    • B44C1/24B44C1/221B44F1/08G06K19/06037G06K19/06103
    • PURPOSE: A decoration integrated with an image code and manufacturing method thereof are provided to enable a user to effectively recognize the image code using a mobile terminal which stores a code recognition application. CONSTITUTION: A decoration model is manufactured(S1100). The decoration model includes a body unit and a code unit. An image code is formed on the code unit. A casted decoration is manufactured using the decoration model(S1200). The casted decoration includes a code surface where the code unit is engraved and a body which has a similar shape with the body unit. The surface of the body and the code surface are processed(S1300). [Reference numerals] (S1100) Step of manufacturing a decoration model including a body unit and a code unit in which an image code is formed; (S1200) Step of manufacturing a casted decoration model including a body, of which shape is the same as the body unit, and a code surface which is obtained by engraving the code unit; (S1300) Step of surface processing the surface of the body and the code surface
    • 目的:提供一种集成了图像代码的装饰及其制造方法,以使用户能够使用存储代码识别应用的移动终端来有效地识别图像代码。 规定:制造装饰模型(S1100)。 装饰模型包括身体单位和代码单元。 在代码单元上形成图像代码。 使用装饰模型制造铸造装饰(S1200)。 铸造的装饰包括代码单元被雕刻的代码表面和与主体单元具有相似形状的主体。 处理体表面和代码表面(S1300)。 (附图标记)(S1100)制造包括主体单元和其中形成图像代码的代码单元的装饰模型的步骤; (S1200)制造包括与身体单元相同形状的主体的铸造装饰模型的步骤以及通过雕刻代码单元获得的代码表面; (S1300)表面处理体表面和编码面的步骤
    • 7. 发明授权
    • CD 표면 연마기
    • ABRADER紧凑盘表面
    • KR101580426B1
    • 2015-12-24
    • KR20150006634
    • 2015-01-14
    • KIM KYOUNG TAE
    • KIM KYOUNG TAE
    • G11B7/26
    • G11B7/26
    • 본발명은, CD(Compact disk : 이하 CD라고칭함)의표면에융착된표시부를연마해서제거함으로써 CD의재질로사용되는폴리카보네이트(Polycarbonate)를재활용할수 있게하는 CD 표면연마기에관한것이다. 본발명에따르면, CD의소재인폴리카보네이트를재활용하기위한 CD 표시부를자동으로고속연마제거할수 있는수단을제시함으로써폐 CD의폴리카보네이트재활용을촉진하고그 수율및 경제성을확보할수 있게한다.
    • 本发明涉及一种CD表面研磨剂,其将融合在光盘表面上的显示部分(称为CD)磨蚀以去除显示部分,以便再循环用作CD的材料的聚碳酸酯。 本发明提供一种能够自动且快速地研磨和除去CD显示部件以再循环用作CD的材料的聚碳酸酯以促进所使用的CD的聚碳酸酯的再循环并提高回收率和经济效率的单元。