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1. 再颁专利

USRE37495E1 Substituted 1-arylpyrazoles 失效
标题翻译：取代的1-芳基吡唑
公开(公告)号：USRE37495E1
公开(公告)日：2002-01-01
申请号：US08984628
申请日：1997-12-03
申请人： Jörg Stetter , Bernd Alig , Stefan Böhm , Achim Bertsch , Pieter Ooms , Christoph Erdelen , Jürgen Hartwig , Ulrike Wachendorff-Neumann , Andreas Turberg , Norbert Mencke
发明人： Jörg Stetter , Bernd Alig , Stefan Böhm , Achim Bertsch , Pieter Ooms , Christoph Erdelen , Jürgen Hartwig , Ulrike Wachendorff-Neumann , Andreas Turberg , Norbert Mencke
IPC分类号： A01N4340
CPC分类号： C07D231/38 , A01N43/56 , C07C255/30 , C07D231/18 , C07D231/44 , C07D401/04
摘要： The invention relates to new substituted 1-arylpyrazoles of the general formula (I) to a plurality of processes for their preparation, and to their use as pesticides.
摘要翻译：本发明涉及通式（I）的新的取代的1-芳基吡唑，用于制备多种方法及其用作农药。

2. 发明授权

US06221810B1 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives 失效
标题翻译： 3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物
公开(公告)号：US06221810B1
公开(公告)日：2001-04-24
申请号：US09052290
申请日：1998-03-31
申请人： Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Böhm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
发明人： Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Böhm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
IPC分类号： A01N4356
CPC分类号： C07D487/04 , A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/08
摘要： There are provided new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) in which A and B are identical or different and independently of one another in each case represent hydrogen, alkyl, alkenyl, alkynyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl or optionally substituted aryl or A and B together represent the bivalent radical of a saturated or unsaturated, optionally substituted, mono-, bi-, tri- or polycyclic system, X represents alkyl, halogen or alkoxy, Y represents hydrogen, alkyl, halogen, alkoxy or halogenoalkyl, Z represents alkyl, halogen or alkoxy, n represents a number 0, 1, 2 or 3, G represents hydrogen (a) or the groups —CO—R1 (b ), —SO2—R3 (d), or E (g), in which E represents a metal ion equivalent or an ammonium ion, L and M represents oxygen and/or sulphur, and R1, R2, R3, R4, R5, R6 and R7 have the meaning given in the text of the application. The new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) have a particularly pronounced activity against animal pests, in particular against insects and arachnids, and against weeds.
摘要翻译：提供式（I）的新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物，其中A和B彼此相同或不同并且彼此独立地表示氢，烷基，烯基，炔基，烷氧基烷基，烷基硫代烷基，环烷基或任选取代的芳基或A和B一起表示饱和或不饱和的任选取代的单，双，三或多环系统的二价基团，X表示烷基，卤素或烷氧基，Y表示氢，烷基，卤素，烷氧基或卤代烷基，Z表示烷基，卤素或烷氧基，n表示数0,1,2或3，G表示氢（a）或基团-CO-R1（b），-SO2-R3 ）或E（g），其中E表示金属离子当量或铵离子，L和M表示氧和/或硫，R1，R2，R3，R4，R5，R6和R7具有式（I）的新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物对动物具有特别显着的活性 l害虫，特别是对昆虫和蜘蛛，以及对杂草。

3. 发明授权

US08433115B2 System and method for multi-image based stent visibility enhancement 有权
标题翻译：用于基于多图像的支架可见度增强的系统和方法
公开(公告)号：US08433115B2
公开(公告)日：2013-04-30
申请号：US12846273
申请日：2010-07-29
申请人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roβmeier
发明人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roβmeier
IPC分类号： G06K9/00
CPC分类号： G06K9/6206 , G06K2209/057 , G06T5/001 , G06T5/20 , G06T5/50 , G06T2207/10016 , G06T2207/10121 , G06T2207/30101
摘要： A method for enhancing stent visibility in digital medical images includes providing a time series of 2-dimensional (2D) images of a stent in a vessel, estimating motion of the stent in a subset of images of the time series of images, estimating motion of clutter in the subset of images, where clutter comprises anatomical structures other than the stent, estimating a clutter layer in the subset of images from the estimated clutter motion, estimating a stent layer in the subset of images from the clutter layer and the estimated clutter motion, and minimizing a functional of the estimated stent motion, the estimated stent layer, the estimated clutter motion, and the estimated clutter layer to in calculate a refined stent layer image, where the refined stent layer image has enhanced visibility of the stent.
摘要翻译：一种用于增强数字医学图像中的支架可视性的方法包括在血管中提供支架的二维（2D）图像的时间序列，估计支架在时间序列图像的图像的子集中的运动，估计运动在图像子集中混乱，其中杂波包括除了支架之外的解剖结构，从估计的杂波运动估计图像子集中的杂波层，估计来自杂波层的图像子集中的支架层和估计的杂波运动并且在计算精制的支架层图像时，将精确的支架层图像具有增强的支架的可视性，并且将估计的支架运动，估计的支架层，估计的杂波运动和估计的杂波层的功能最小化。

4. 发明授权

US08249355B2 Method and device for noise suppression in medical images 有权
标题翻译：医学图像中噪声抑制的方法和装置
公开(公告)号：US08249355B2
公开(公告)日：2012-08-21
申请号：US12313566
申请日：2008-11-21
申请人： Stefan Böhm , Sandra Martin
发明人： Stefan Böhm , Sandra Martin
IPC分类号： G06K9/40 , G06T5/00
CPC分类号： A61B6/504 , A61B6/12 , G06T5/002 , G06T7/13 , G06T2207/10116 , G06T2207/20012 , G06T2207/30004
摘要： The invention relates to a method for noise suppression in medical images comprising steps of measuring the gradient field strength of an image pixel and selecting a suitable filter mask for noise suppression as a function of the gradient field strength, with the value of the gradient field strength being compared with a predetermined threshold value. The method is repeated when an additional image pixel is selected. A decision is made per read-in image pixel as to which type of filter mask is used for filtering. A selection can be made between filter masks of different sizes or isotropic or anisotropic or directional filter masks. The decision is based on the measured gradient field strength of the respective pixel. The use of different filter masks allows the signal-to-noise ratio to be improved, without distorting structures like edges for instance and without generating artificial structures in homogenous noise regions.
摘要翻译：本发明涉及一种医学图像中的噪声抑制方法，包括以下步骤：测量图像像素的梯度场强，并根据梯度场强度选择合适的噪声抑制滤波器掩模，梯度场强与预定阈值进行比较。当选择附加图像像素时重复该方法。每个读入图像像素决定使用哪种类型的滤波器掩码进行滤波。可以选择不同尺寸的滤光片或各向同性或各向异性或方向滤光片。该决定基于相应像素的测量的梯度场强度。使用不同的滤波器掩模允许提高信噪比，而不会像边缘这样的结构变形，而不会在同质噪声区域中产生人造结构。

5. 发明授权

US07539336B2 X-ray diagnostic apparatus and method for operating an x-ray diagnostic apparatus for determining quality values 有权
标题翻译：用于操作用于确定质量值的X射线诊断装置的X射线诊断装置和方法
公开(公告)号：US07539336B2
公开(公告)日：2009-05-26
申请号：US11293444
申请日：2005-12-02
申请人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
发明人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
IPC分类号： G06K9/00
CPC分类号： G06T7/0002 , A61B6/504 , A61B6/583 , H04N5/325 , Y10S128/922
摘要： The invention relates to an angiographic x-ray diagnostic apparatus with an x-ray radiator having an x-ray tube, with a patient positioning table having a radiation-transparent positioning plate and mattress, with an x-ray detector, with an imaging system, an image processing unit and a measuring device to which the output signals of the x-ray detector are fed and which has a first device for determining a value determining the reproduction quality of clinically relevant objects, a second device for determining local variances of the noise in a homogenous image region of different x-ray images and a device for taking the ratio of the output values of the two devices.
摘要翻译：本发明涉及具有x射线管的x射线辐射器的血管造影X射线诊断装置，其中患者定位台具有辐射透明的定位板和床垫，具有x射线检测器，具有成像系统，图像处理单元和测量装置，X射线检测器的输出信号被馈送到该图像处理单元和测量装置，并且具有用于确定确定临床相关对象的再现质量的值的第一装置，用于确定临床相关对象的再现质量的第二装置，在不同X射线图像的均匀图像区域中的噪声和用于获取两个装置的输出值的比率的装置。

6. 发明授权

US11207029B2 Method for denoising time series images of a moved structure for medical devices 有权
公开(公告)号：US11207029B2
公开(公告)日：2021-12-28
申请号：US15478853
申请日：2017-04-04
申请人： Stefan Böhm , Boris Stowasser
发明人： Stefan Böhm , Boris Stowasser
IPC分类号： A61B6/00 , G06T5/00 , G06T7/00 , A61B5/00 , G06T7/11
摘要： Embodiments provide a method for denoising time series images of a moved structure for a medical device. A movement detector detects the moved structure. The movement detector obtains a measurement of the similarity of two images that each represent the same section of the moved structure. The two images originate from two different time series images. A ratio between spatial and temporal denoising is defined for the section as a function of the measurement of the similarity.

7. 发明授权

US08355557B2 System and method for decomposed temporal filtering for X-ray guided intervention application 有权
标题翻译：用于X射线引导干预应用的分解时间滤波的系统和方法
公开(公告)号：US08355557B2
公开(公告)日：2013-01-15
申请号：US12571487
申请日：2009-10-01
申请人： Yunqiang Chen , Ti-chiun Chang , Tong Fang , Sandra Knoth , Stefan Böhm , Peter Durlak
发明人： Yunqiang Chen , Ti-chiun Chang , Tong Fang , Sandra Knoth , Stefan Böhm , Peter Durlak
IPC分类号： G06K9/00 , A61B6/02 , A61B6/00
CPC分类号： G06T5/50 , G06T2207/20224 , G06T2207/30041 , G06T2207/30101
摘要： A method for temporally filtering medical images during a fluoroscopy guided intervention procedure includes providing a mask image, a fluoroscopy intervention image acquired at a current time during a medical intervention procedure, forming a subtraction image by subtracting the mask image from the intervention image, calculating a motion image of a moving structure in the subtraction image, forming a residual image by subtracting the motion image from the subtraction image, temporally filtering the residual image with a filtered image from a previous time, and adding the motion image to the temporally filtered residual image.
摘要翻译：一种在荧光透视引导介入手术过程中对医学图像进行临时过滤的方法包括提供掩模图像，在医疗介入过程中当前时间获取的荧光透视干预图像，通过从干预图像中减去掩模图像形成减影图像，在减法图像中的运动结构的运动图像，通过从减法图像中减去运动图像形成残差图像，并用先前时间用滤波图像对剩余图像进行时间滤波，并将运动图像与时间滤波残差图像相加。

8. 发明授权

US07826651B2 Method for operating an x-ray diagnostic apparatus for determining quality values 有权
标题翻译：用于操作用于确定质量值的x射线诊断装置的方法
公开(公告)号：US07826651B2
公开(公告)日：2010-11-02
申请号：US12401295
申请日：2009-03-10
申请人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
发明人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
IPC分类号： G06K9/00
CPC分类号： G06T7/0002 , A61B6/504 , A61B6/583 , H04N5/325 , Y10S128/922
摘要： A method for checking an x-ray diagnostic apparatus is provided. Fluoroscopic series of x-ray images of a technical phantom are digitally acquired and stored. Difference between a dynamic image and a background image is calculated. A measuring field is predicted. Priori information about the shape of a clinically relevant object is determined. Hough transformation on a gray value image corresponding to the difference is applied. Contrast of the object from the Hough-transformed gray value image is determined. A square of the determined contrast is calculated. A noise variance is calculated by determining a sum of a noise variance of a homogenous image region and a variance of the background image. A contrast-to-noise ratio of the determined contrast and the calculated noise variance is determined. A square of the contrast-to-noise ratio is dynamically averaged. A Clinical Relevant Fluoroscopy Performance index for the x-ray diagnostic apparatus is determined.
摘要翻译：提供了一种用于检查x射线诊断装置的方法。数字获取和存储技术幻像的荧光系列X射线图像。计算动态图像和背景图像之间的差异。预测测量场。确定关于临床相关对象的形状的优先信息。应用与差异对应的灰度值图像上的霍夫变换。确定来自霍夫变换灰度值图像的对象的对比度。计算确定的对比度的平方。通过确定均匀图像区域的噪声方差和背景图像的方差的和来计算噪声方差。确定所确定的对比度和所计算的噪声方差的对比噪声比。动态平均对比噪声比的平方。确定X线诊断仪的临床相关荧光检查性能指标。

9. 发明申请

US20090257637A1 Method for providing variously processed image data and x-ray image system 有权
标题翻译：用于提供各种处理的图像数据和x射线图像系统的方法
公开(公告)号：US20090257637A1
公开(公告)日：2009-10-15
申请号：US12310940
申请日：2007-09-20
申请人： Stefan Böhm , Klaus Finkler , Bernhard Geiger
发明人： Stefan Böhm , Klaus Finkler , Bernhard Geiger
IPC分类号： G06K9/00
CPC分类号： G06T5/50 , G06T11/00 , G06T15/503 , G06T2200/24 , G06T2207/30004 , G06T2210/52
摘要： Modern image processing systems for the postprocessing of X-ray images require a large number of input parameters and take a great deal of time. So that calculations do not need to be made sequentially for different sets of input parameters, parallel processors are used, in which the same image processing program is executed in each case, but with different input parameters in each case. A large number of processed X-ray images is thus obtained, which in particular can also be displayed simultaneously. From the multiple processed x-ray images, a repeated postprocessing of a processed x-ray image can take place by mixing.
摘要翻译：用于后期处理X射线图像的现代图像处理系统需要大量的输入参数并花费大量的时间。因此，对于不同的输入参数集，不需要依次进行计算，因此使用并行处理器，其中在每种情况下执行相同的图像处理程序，但是在每种情况下具有不同的输入参数。因此获得了大量的经处理的X射线图像，其特别地也可以同时显示。从多个经处理的X射线图像中，可以通过混合来进行经处理的X射线图像的重复后处理。

10. 发明授权

US07148903B2 Image reconstruction method and computer program product 有权
标题翻译：图像重建方法和计算机程序产品
公开(公告)号：US07148903B2
公开(公告)日：2006-12-12
申请号：US10778381
申请日：2004-02-13
申请人： Thomas Brunner , Stefan Böhm , Joachim Hornegger , Christian Neumair
发明人： Thomas Brunner , Stefan Böhm , Joachim Hornegger , Christian Neumair
IPC分类号： G09G5/00
CPC分类号： G06T17/00 , G06T11/005 , G06T2207/30004
摘要： In a method for reconstructing a three-dimensional subject a number of projections of a three-dimensional subject is acquired by an acquisition arrangement. Each projection is a dataset of spatially contiguous data values. The projections are provided to a computer. A first part of the data values of the projections is replaced by new data values, and a second part of the data values of the projections remains unchanged. Thus changed projections are generated, using which a reconstruction of an image of the subject is determined by the computer.
摘要翻译：在重建三维对象的方法中，通过采集装置获取三维对象的多个投影。每个投影是空间连续数据值的数据集。将投影提供给计算机。投影的数据值的第一部分被新的数据值替代，并且投影的数据值的第二部分保持不变。因此，产生了由计算机确定被摄体图像的重建的改变的投影。

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