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1. 发明申请

WO2007047189A2 TARGETED BIOCIDES 审中-公开
标题翻译：目标生物
公开(公告)号：WO2007047189A2
公开(公告)日：2007-04-26
申请号：PCT/US2006/039361
申请日：2006-10-10
申请人： IOGENETICS, LLC , IMBODEN, Michael , RIGGS, Michael, W. , SCHAEFER, Deborah
发明人： IMBODEN, Michael , RIGGS, Michael, W. , SCHAEFER, Deborah
IPC分类号： A61K39/40 , C07K16/12
CPC分类号： C07K16/14 , A61K2039/505 , C07K16/20 , C07K2317/12 , C07K2317/622 , C07K2317/76 , C07K2319/30 , C07K2319/55
摘要： The present invention relates to retroviral constructs that encode novel monoclonal antibodies, novel fusion proteins, and chimeric monoclonal antibodies and to methods of using and producing the same. In particular, the present invention relates to methods of producing a fusion protein comprising a microorganism targeting molecule ( e.g., immunoglobulin or innate immune system receptor molecule) and a biocide ( e.g ., bactericidal enzyme) in transgenic animals ( e.g., bovines) and in cell cultures. The present invention also relates to therapeutic and prophylactic methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in health care ( e.g ., human and veterinary), agriculture ( e.g., animal and plant production), and food processing ( e.g., beef carcass processing). The present invention also relates to methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in various diagnostic applications in number of diverse fields such as agriculture, medicine, and national defense.
摘要翻译：本发明涉及编码新单克隆抗体，新型融合蛋白和嵌合单克隆抗体的逆转录病毒构建体及其使用和生产方法。特别地，本发明涉及在转基因动物（例如牛）和细胞中产生包含微生物靶向分子（例如，免疫球蛋白或先天性免疫系统受体分子）和杀生物剂（例如，杀菌酶）的融合蛋白的方法文化。本发明还涉及在医疗保健（例如人类和兽医），农业（例如动物和植物生产）和食品加工（例如，动物和植物生产）中使用包含微生物靶向分子和杀生物剂的融合蛋白的治疗和预防方法，牛肉屠体处理）。本发明还涉及在农业，医药，国防等不同领域的多种诊断应用中使用包含微生物靶向分子和杀生物剂的融合蛋白的方法。

2. 发明公开

EP1933874A2 TARGETED BIOCIDES 审中-公开
标题翻译：靶向杀生物
公开(公告)号：EP1933874A2
公开(公告)日：2008-06-25
申请号：EP06825629.6
申请日：2006-10-10
申请人： IOGENETICS, LLC , Arizona Board of Regents on behalf of the University of Arizona
发明人： IMBODEN, Michael , RIGGS, Michael, W. , SCHAEFER, Deborah
IPC分类号： A61K39/40 , C07K16/12
CPC分类号： C07K16/14 , A61K2039/505 , C07K16/20 , C07K2317/12 , C07K2317/622 , C07K2317/76 , C07K2319/30 , C07K2319/55
摘要： The present invention relates to retroviral constructs that encode novel monoclonal antibodies, novel fusion proteins, and chimeric monoclonal antibodies and to methods of using and producing the same. In particular, the present invention relates to methods of producing a fusion protein comprising a microorganism targeting molecule (e.g., immunoglobulin or innate immune system receptor molecule) and a biocide (e.g., bactericidal enzyme) in transgenic animals (e.g., bovines) and in cell cultures. The present invention also relates to therapeutic and prophylactic methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in health care (e.g., human and veterinary), agriculture (e.g., animal and plant production), and food processing (e.g., beef carcass processing). The present invention also relates to methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in various diagnostic applications in number of diverse fields such as agriculture, medicine, and national defense.

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