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1. 发明授权

US07998129B2 Device for facilitating cardioplegia delivery in patients with aortic insufficiency 有权
标题翻译：用于促进主动脉瓣关闭不全患者心脏停搏的装置
公开(公告)号：US07998129B2
公开(公告)日：2011-08-16
申请号：US10591963
申请日：2005-03-10
申请人： Howard C Herrmann , Y Joseph Woo
发明人： Howard C Herrmann , Y Joseph Woo
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61B17/12022 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B2017/00243 , A61B2017/1205 , A61M1/3659 , A61M1/3664 , A61M25/0084
摘要： A method and device that addresses the problem of an incompetent aortic valve by using a simple cardioplegia catheter that can deliver cardioplegia solution to the coronary arteries through the usual aortic cannulation site even in the presence of aortic valve incompetence. The device includes a cardioplegia cannula (32) with an additional lumen containing a nitinol wire (34) inside it that allows advancement of a folded nitinol umbrella (36) with a non-porous membrane or a compressed nitinol ring that covers the aortic valve when opened. During installation, after puncture of the aorta by the coaxial needle and removal of the coaxial needle but before installation of the cardioplegia solution through the central lumen of the catheter, the nitinol umbrella (in folded position) or nitinol ring (in compressed position) is advanced through the second lumen into the aorta just above the aortic valve. The nitinol umbrella is unfolded using the nitinol wire to expose the inverted umbrella configuration with attached membrane and is then advanced as a unit with the cardioplegia catheter until the nitinol umbrella covers the aortic valve at its deployed position.
摘要翻译：一种通过使用简单的心麻痹导管来解决无能的主动脉瓣的问题的方法和装置，即使在存在主动脉瓣不能力的情况下，也可以通过通常的主动脉插管部位将心麻痹液提供给冠状动脉。该装置包括心麻痹套管（32），其具有在其内部含有镍钛诺导线（34）的附加内腔，其允许利用覆盖主动脉瓣的无孔膜或压缩的镍钛诺环使折叠的镍钛诺（36）推进，开了在安装过程中，在通过同轴针穿刺主动脉并取出同轴针之后，但是在通过导管的中央腔安装心麻痹液之前，尼诺诺伞（折叠位置）或镍钛诺环（压缩位置）是通过第二管腔进入主动脉瓣正上方的主动脉。镍钛诺伞使用镍钛诺丝展开，暴露具有附着膜的倒置伞形结构，然后以心麻痹导管作为一个单元前进，直到镍钛诺伞在其展开位置覆盖主动脉瓣。

2. 发明授权

US07621948B2 Percutaneous heart valve 有权
标题翻译：经皮心脏瓣膜
公开(公告)号：US07621948B2
公开(公告)日：2009-11-24
申请号：US10565142
申请日：2004-07-20
申请人： Howard C Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
发明人： Howard C Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/243 , Y10S623/904
摘要： A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to the annular ring, claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws in the second position, and leaflet membranes connected to the annular ring, the body member and/or the legs, the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve is designed such that upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding the heart valve in place. The body member and claws may be integrated into a one-piece design. The heart valve may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart.
摘要翻译：经皮插入的双稳态心脏瓣膜假体折叠在导管内，用于经血管输送到患者的心脏用于植入。心脏瓣膜具有环形环，主体部件具有多个腿部，每个腿部在一端连接到环形环，通过施加外力从第一位置到第二位置可调节的爪，以允许进入周围的心脏组织进入第二位置的爪，以及连接到环形环，身体构件和/或腿的小叶膜，小叶膜具有用于阻止血液流过的第一位置和用于允许血液流动的第二位置通过。心脏瓣膜被设计成使得当去除外力时，爪弹性地回复到第一位置，以便夹紧位于爪内的心脏组织，从而将心脏瓣膜保持在适当位置。主体构件和爪可以集成成一体式设计。心脏瓣膜可用作二尖瓣，主动脉瓣，肺动脉瓣或三尖瓣的假体，通过使环形圈适应于心脏的相应二尖瓣，主动脉，肺或三尖瓣开口。

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