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1. 发明申请

US20100042208A1 Percutaneous Heart Valve 有权
标题翻译：经皮心脏瓣膜
公开(公告)号：US20100042208A1
公开(公告)日：2010-02-18
申请号：US12582986
申请日：2009-10-21
申请人： Howard C. Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
发明人： Howard C. Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
IPC分类号： A61F2/24 , A61M31/00
CPC分类号： A61F2/2412 , A61F2/243 , Y10S623/904
摘要： A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to the annular ring, claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws in the second position, and leaflet membranes connected to the annular ring, the body member and/or the legs, the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve is designed such that upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding the heart valve in place. The body member and claws may be integrated into a one-piece design. The heart valve may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart.
摘要翻译：经皮插入的双稳态心脏瓣膜假体折叠在导管内，用于经血管输送到患者的心脏用于植入。心脏瓣膜具有环形环，主体部件具有多个腿部，每个腿部在一端连接到环形环，通过施加外力从第一位置到第二位置可调节的爪，以允许进入周围的心脏组织进入第二位置的爪，以及连接到环形环，身体构件和/或腿的小叶膜，小叶膜具有用于阻止血液流过的第一位置和用于允许血液流动的第二位置通过。心脏瓣膜被设计成使得当去除外力时，爪弹性地回复到第一位置，以便夹紧位于爪内的心脏组织，从而将心脏瓣膜保持在适当位置。主体构件和爪可以集成成一体式设计。心脏瓣膜可用作二尖瓣，主动脉瓣，肺动脉瓣或三尖瓣的假体，通过使环形圈适应于心脏的相应二尖瓣，主动脉，肺或三尖瓣开口。

2. 发明授权

US07621948B2 Percutaneous heart valve 有权
标题翻译：经皮心脏瓣膜
公开(公告)号：US07621948B2
公开(公告)日：2009-11-24
申请号：US10565142
申请日：2004-07-20
申请人： Howard C Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
发明人： Howard C Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/243 , Y10S623/904
摘要： A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to the annular ring, claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws in the second position, and leaflet membranes connected to the annular ring, the body member and/or the legs, the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve is designed such that upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding the heart valve in place. The body member and claws may be integrated into a one-piece design. The heart valve may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart.
摘要翻译：经皮插入的双稳态心脏瓣膜假体折叠在导管内，用于经血管输送到患者的心脏用于植入。心脏瓣膜具有环形环，主体部件具有多个腿部，每个腿部在一端连接到环形环，通过施加外力从第一位置到第二位置可调节的爪，以允许进入周围的心脏组织进入第二位置的爪，以及连接到环形环，身体构件和/或腿的小叶膜，小叶膜具有用于阻止血液流过的第一位置和用于允许血液流动的第二位置通过。心脏瓣膜被设计成使得当去除外力时，爪弹性地回复到第一位置，以便夹紧位于爪内的心脏组织，从而将心脏瓣膜保持在适当位置。主体构件和爪可以集成成一体式设计。心脏瓣膜可用作二尖瓣，主动脉瓣，肺动脉瓣或三尖瓣的假体，通过使环形圈适应于心脏的相应二尖瓣，主动脉，肺或三尖瓣开口。

3. 发明授权

US08118866B2 Method for heart valve implantation 有权
标题翻译：心脏瓣膜植入方法
公开(公告)号：US08118866B2
公开(公告)日：2012-02-21
申请号：US12582986
申请日：2009-10-21
申请人： Howard C. Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
发明人： Howard C. Herrmann , Nilesh Mankame , Suresh G. K. Ananthasuresh
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/243 , Y10S623/904
摘要： A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to the annular ring, claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws in the second position, and leaflet membranes connected to the annular ring, the body member and/or the legs, the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve is designed such that upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding the heart valve in place. The body member and claws may be integrated into a one-piece design. The heart valve may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart.
摘要翻译：经皮插入的双稳态心脏瓣膜假体折叠在导管内，用于经血管输送到患者的心脏用于植入。心脏瓣膜具有环形环，主体部件具有多个腿部，每个腿部在一端连接到环形环，通过施加外力从第一位置到第二位置可调节的爪，以允许进入周围的心脏组织进入第二位置的爪，以及连接到环形环，身体构件和/或腿的小叶膜，小叶膜具有用于阻止血液流过的第一位置和用于允许血液流动的第二位置通过。心脏瓣膜被设计成使得当去除外力时，爪弹性地回复到第一位置，以便夹紧位于爪内的心脏组织，从而将心脏瓣膜保持在适当位置。主体构件和爪可以集成成一体式设计。心脏瓣膜可用作二尖瓣，主动脉瓣，肺动脉瓣或三尖瓣的假体，通过使环形圈适应于心脏的相应二尖瓣，主动脉，肺或三尖瓣开口。

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