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1. 发明专利

JP2014138874A Medicament mixing system 审中-公开
标题翻译：药物混合系统
公开(公告)号：JP2014138874A
公开(公告)日：2014-07-31
申请号：JP2014042595
申请日：2014-03-05
申请人： Hospira Inc , ホスピラ・インコーポレイテツド
发明人： YEI F MOY , PYTEL STANLEY F , JOHN S ZIEGLER , JESSE C DARLEY , DOUGLAS S RODENKIRCH
IPC分类号： A61J1/05 , A61J3/00 , A61M5/168
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/1462 , A61J1/1475 , A61J1/2041 , A61J1/2051 , A61J1/2055 , A61J1/2089 , A61M2039/0036 , B65B3/003 , B65D51/002 , B65D75/5883 , B65D81/3211
摘要： PROBLEM TO BE SOLVED: To provide reconstitution systems and systems to mix the contents of two containers from outside the containers.SOLUTION: This invention relates to a system for mixing or reconstituting a medicament contained in a first container 412 with a diluent or fluid contained in a second container 414. The second container has a port docking assembly 418 to engage with the first container. The first container can rotate in the port docking assembly and can slide in axial direction. The port docking assembly has an actuator for pressing a plug fluidly sealing the first container into the first container. The port docking assembly also has a movable plug configured to fluidly seal the second container at a first docking position and provide access to the inside of the second container at a second activated position. Thus, when the first and second containers are at the second activated position, fluid communication is provided between the first and second containers.
摘要翻译：要解决的问题：提供重建系统和系统以从容器外部混合两个容器的内容物。解决方案：本发明涉及一种用于将包含在第一容器412中的药物与包含在第一容器412中的稀释剂或流体混合或重构的系统第二容器414.第二容器具有端口对接组件418以与第一容器接合。第一个容器可以在端口对接组件中旋转，并可沿轴向滑动。端口对接组件具有致动器，用于将流体地密封第一容器的插头压入第一容器。端口对接组件还具有可移动插头，其构造成在第一对接位置处流体地密封第二容器并在第二启动位置提供对第二容器内部的通路。因此，当第一和第二容器处于第二启动位置时，在第一和第二容器之间提供流体连通。

2. 发明专利

JP2011245320A Port closure system for intravenous fluid container 审中-公开
标题翻译：用于静脉流体容器的端口封闭系统
公开(公告)号：JP2011245320A
公开(公告)日：2011-12-08
申请号：JP2011151504
申请日：2011-07-08
申请人： Hospira Inc , ホスピラ・インコーポレイテツド
发明人： DOMKOWSKI JOHN , BURG RICHARD E , CASPARY GLENN A , DANIELS MARC M , OSTLER MARK I , PASINI JOSEPH , PYTEL STANLEY F , SERGOT JOHN , WECKER SHELDON M
IPC分类号： A61J1/10
CPC分类号： A61J1/10 , A61J1/14 , A61M5/162 , A61M39/165 , B29C65/02 , B29C65/08 , B29C65/14 , B29C66/1312 , B29C66/542 , B29C66/543 , B29L2031/7148
摘要： PROBLEM TO BE SOLVED: To provide an additive port closure assembly to reduce the possibility of contamination during storage and use.SOLUTION: A port closure system 10 for use with a fluid container having fluid ports 14, 16 includes administrative and additive port closure assemblies 88, 22. A cap assembly 38 mates with an administrative housing 90, sealing the interior surface of the administrative housing 90. A removable cap 44 provides access to the interior surface. The additive assembly 88 receives a needle and includes a reseal housing 24 which seals closed another fluid port. Another cap assembly 38 mates with the reseal housing 24, sealing an interior face of the reseal housing 24. Another removable cap 44 provides access to the interior face. A reseal element is mechanically retained between the reseal housing 24 and cap assembly 38.
摘要翻译：要解决的问题：提供添加剂端口封闭组件，以减少在储存和使用期间污染的可能性。解决方案：用于与具有流体端口14,16的流体容器一起使用的端口封闭系统10包括管理和加法端口封闭组件88,22。盖组件38与管理壳体90配合，密封管壳可拆卸盖44提供进入内表面的通道。添加剂组件88接收针并且包括密封封闭的另一个流体端口的重新密封壳体24。另一个盖组件38与重新密封外壳24配合，密封重新密封外壳24的内表面。另一可拆卸盖44提供对内表面的通路。重新密封元件被机械地保持在重新密封壳体24和盖组件38之间。版权所有（C）2012，JPO＆INPIT

3. 发明申请

WO2006071781A3 PORT CLOSURE SYSTEM FOR INTRAVENOUS FLUID CONTAINER 审中-公开
标题翻译：用于静脉流体容器的端口封闭系统
公开(公告)号：WO2006071781A3
公开(公告)日：2006-08-17
申请号：PCT/US2005046819
申请日：2005-12-21
申请人： HOSPIRA INC , DOMKOWSKI JOHN , BURG RICHARD E , CASPARY GLENN A , DANIELS MARC M , OSTLER MARK I , PASINI JOSEPH , PYTEL STANLEY F , SERGOT JOHN , WECKER SHELDON M
发明人： DOMKOWSKI JOHN , BURG RICHARD E , CASPARY GLENN A , DANIELS MARC M , OSTLER MARK I , PASINI JOSEPH , PYTEL STANLEY F , SERGOT JOHN , WECKER SHELDON M
IPC分类号： A61M5/00
CPC分类号： A61J1/1406 , A61J1/10 , A61M5/162 , A61M39/165 , B29C65/02 , B29C65/08 , B29C65/14 , B29C66/1312 , B29C66/542 , B29C66/543 , B29L2031/7148
摘要： A port closure system for use with a fluid container having fluid ports includes administrative and additive port closure assemblies. The administrative assembly receives a piercing pin and includes an administrative housing which seals closed one fluid port. A sleeve extends from an interior surface past a base surface in the administrative housing. The sleeve has an upper portion and a lower portion, of differing diameters. A cap assembly mates with the administrative housing, sealing the interior surface of the administrative housing. A removable cap provides access to the interior surface. The additive assembly receives a needle and includes a reseal housing which seals closed another fluid port. Another cap assembly mates with the reseal housing, sealing an interior face of the reseal housing. Another removable cap provides access to the interior face. A reseal element is mechanically retained between the reseal housing and cap assembly.
摘要翻译：与具有流体端口的流体容器一起使用的端口封闭系统包括管理和加法端口封闭组件。管理组件接收穿孔针，并包括封闭一个流体端口的管理外壳。套管从内表面延伸经过管理外壳中的基面。套筒具有不同直径的上部和下部。盖帽与行政房屋配合，密封行政房屋的内部表面。可拆卸盖可以进入内表面。添加剂组件接收针并且包括密封封闭的另一流体端口的重新密封壳体。另一个盖组件与重新密封外壳配合，密封重新密封外壳的内表面。另一个可拆卸盖可以进入内部面。重新密封元件机械地保持在重新密封壳体和盖组件之间。

4. 发明申请

WO2008003045A3 MEDICAL FLUID CONTAINER 审中-公开
标题翻译：医用流体容器
公开(公告)号：WO2008003045A3
公开(公告)日：2008-12-11
申请号：PCT/US2007072361
申请日：2007-06-28
申请人： HOSPIRA INC , BURG RICHARD E , ROSKRES MARTIN H , RAMSAY GEORGE M , OSTLER MARK I , DANIELS MARC M , BAKER MARY BETH , DOMKOWSKI JOHN , CASPARY GLENN A , PASINI JOSEPH , PYTEL STANLEY F , SERGOT JOHN , WECKER SHELDON M
发明人： BURG RICHARD E , ROSKRES MARTIN H , RAMSAY GEORGE M , OSTLER MARK I , DANIELS MARC M , BAKER MARY BETH , DOMKOWSKI JOHN , CASPARY GLENN A , PASINI JOSEPH , PYTEL STANLEY F , SERGOT JOHN , WECKER SHELDON M
IPC分类号： A61B19/00 , A61M19/00
CPC分类号： A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/18 , A61J1/201 , A61J1/2096 , A61M5/162 , A61M39/165 , B29C65/02 , B29C65/08 , B29C65/14 , B29C66/1122 , B29C66/12821 , B29C66/1286 , B29C66/1312 , B29C66/53263 , B29C66/5344 , B29C66/542 , B29C66/71 , B29C66/72341 , B29C66/72343 , B29C66/8322 , B29L2031/7148 , B29K2023/14 , B29K2023/00 , B29K2023/12 , B29K2023/08
摘要： A flexible non-PVC, non-DEHP polyolefin container or bag for medical fluids has an elongated container body formed of polyolefin film. The container has one or more ports equipped with a polyolefin fill tube and port closure assembly. The container includes a concave seam on at least one of its longitudinal sides.
摘要翻译：用于药液的柔性非PVC，非DEHP聚烯烃容器或袋具有由聚烯烃薄膜形成的细长容器体。该容器具有一个或多个配备有聚烯烃填充管和端口闭合组件的端口。该容器在其至少一个纵向侧面上包括凹形接缝。

5. 发明专利

AU2013237696B2 Medicament admixing system 未知
公开(公告)号：AU2013237696B2
公开(公告)日：2015-09-24
申请号：AU2013237696
申请日：2013-10-03
申请人： HOSPIRA INC
发明人： RODENKIRCH DOUGLAS S , DARLEY JESSE C , MOY YEI F , PYTEL STANLEY F , ZIEGLER JOHN S
IPC分类号： A61F5/30
摘要： MEDICAMENT ADMIXING SYSTEM A system (410) for mixing or reconstituting a drug contained in a first container (412) with a diluent or fluid contained in a second container (414). The second container (414) has a port docking assembly (418) for engaging the first container (412). The first container (412) is rotatable and axially slidable within the port docking assembly (418). The port docking assembly (418) has an actuator (484) to urge a stopper fluidly sealing the first container into the interior of the first container (412). The port docking assembly (418) further includes a movable plug (489) constructed to fluidly seal the second container (414) in a first, docked position and to provide access to the interior of the second container (414) in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

6. 发明专利

ES2425541T3 Sistema de mezclado de medicamento 未知
公开(公告)号：ES2425541T3
公开(公告)日：2013-10-16
申请号：ES10160160
申请日：2008-08-01
申请人： HOSPIRA INC
发明人： MOY YEI F , PYTEL STANLEY F , ZIEGLER JOHN S , DARLEY JESSE C , RODENKIRCH DOUGLAS S
IPC分类号： A61J1/20 , A61J1/10 , B65D51/00 , B65D75/58 , B65D81/32
摘要： Sistema (410) para mezclar un medicamento en un primer envase (412) con un fluido en un segundo envase(414), que comprende: un primer envase (412) que define una abertura (424) y una cavidad interna (426) conectada de manera fluidaa dicha abertura (424); un obturador (428) situado dentro de dicha abertura (424) definida por dicho primer envase (412), sellandofrente a los fluidos dicho obturador (428) a dicha cavidad interna (426) definida por dicho primer 10 envase (412)de un ambiente externo de dicho primer envase (412); un elemento de cuerpo (416) situado alrededor de al menos una parte de dicho primer envase (412),presentando dicho elemento de cuerpo (416) un primer elemento de acoplamiento (450) que se extienderadialmente desde el mismo; un segundo envase (414) que define una cavidad interior (415); una carcasa (482) de boca de entrada conectada a dicho segundo envase (414), definiendo dicha carcasa(482) de boca de entrada una primera abertura en un primer extremo (494) del mismo para recibir dicho primerenvase (412), y una segunda abertura (514) en un segundo extremo (496) del mismo, y un tapón (489) móvilque sella dicha segunda abertura (514) definida por dicha carcasa (482) de boca de entrada; un segundo elemento de acoplamiento (486) situado dentro de una primera cavidad (506) definida por dicha decarcasa (482) de boca de entrada, estando dicho segundo elemento de acoplamiento (486) realizado paraacoplarse con dicho primer elemento de acoplamiento (450) cuando dicho primer envase (412) está insertadodentro de dicha primera abertura de dicha carcasa (482) de boca de entrada; y un actuador (484) dispuesto dentro de dicha cavidad interior (506) definida por dicha carcasa (482) de boca deentrada, estando configurado dicho tapón (489) para moverse axialmente en relación con dicho actuador (484),presentando dicho actuador (484) una pluralidad de elementos de pared lateral (501) que se extiendenaxialmente hacia dicha primera abertura en dicho primer extremo (494) de dicha carcasa (482) de boca deentrada, definiendo dicha pluralidad de elementos de pared lateral (501) una o más aberturas (505) entre losmismos, definiendo dichos elementos de pared lateral (501) de dicho actuador (484) una cavidad central (521),estando dicho actuador (484) realizado para mover dicho obturador (428) desde una primera posición anclada,en la que el mismo sella frente a los fluidos dicho primer envase (412) hasta una segunda posición activada, enla que está ubicada en dicha cavidad interna (426) definida por dicho primer envase (412), por medio de lo cualen la posición activada hay comunicación fluídica entre el primer envase (412) y el segundo envase (414).

7. 发明专利

AU2009248480A1 Port closure system for intravenous fluid container 未知
公开(公告)号：AU2009248480A1
公开(公告)日：2010-01-07
申请号：AU2009248480
申请日：2009-12-14
申请人： HOSPIRA INC
发明人： DOMKOWSKI JOHN , PYTEL STANLEY F , CASPARY GLENN A , WECKER SHELDON M , OSTLER MARK I , BURG RICHARD E , PASINI JOSEPH , SERGOT JOHN , DANIELS MARC M
IPC分类号： B65D51/00
摘要： A port closure system for use with a fluid container having fluid ports includes administrative and additive port closure assemblies. The administrative assembly receives a piercing pin and includes an administrative housing which seals closed one fluid port. A sleeve extends from an interior surface past a base surface in the administrative housing. The sleeve has an upper portion and a lower portion, of differing diameters. A cap assembly mates with the administrative housing, sealing the interior surface of the administrative housing. A removable cap provides access to the interior surface. The additive assembly receives a needle and includes a reseal housing which seals closed another fluid port. Another cap assembly mates with the reseal housing, sealing an interior face of the reseal housing. Another removable cap provides access to the interior face. A reseal element is mechanically retained between the reseal housing and cap assembly.

8. 发明专利

AU2007265010A1 Medical fluid container 未知
公开(公告)号：AU2007265010A1
公开(公告)日：2008-01-03
申请号：AU2007265010
申请日：2007-06-28
申请人： HOSPIRA INC
发明人： BAKER MARY BETH , BURG RICHARD E , ROSKRES MARTIN H , RAMSAY GEORGE M , PASINI JOSEPH , WECKER SHELDON M , DANIELS MARC M , DOMKOWSKI JOHN , SERGOT JOHN , CASPARY GLENN A , PYTEL STANLEY F , OSTLER MARK I
IPC分类号： A61B19/00 , A61M19/00

9. 发明专利

AU2013237696A1 Medicament admixing system 未知
公开(公告)号：AU2013237696A1
公开(公告)日：2013-10-24
申请号：AU2013237696
申请日：2013-10-03
申请人： HOSPIRA INC
发明人： RODENKIRCH DOUGLAS S , DARLEY JESSE C , MOY YEI F , PYTEL STANLEY F , ZIEGLER JOHN S
IPC分类号： A61F5/30
摘要： MEDICAMENT ADMIXING SYSTEM A system (410) for mixing or reconstituting a drug contained in a first container (412) with a diluent or fluid contained in a second container (414). The second container (414) has a port docking assembly (418) for engaging the first container (412). The first container (412) is rotatable and axially slidable within the port docking assembly (418). The port docking assembly (418) has an actuator (484) to urge a stopper fluidly sealing the first container into the interior of the first container (412). The port docking assembly (418) further includes a movable plug (489) constructed to fluidly seal the second container (414) in a first, docked position and to provide access to the interior of the second container (414) in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

10. 发明专利

AU2008293763B2 Medicament admixing system 未知
公开(公告)号：AU2008293763B2
公开(公告)日：2013-04-18
申请号：AU2008293763
申请日：2008-08-01
申请人： HOSPIRA INC
发明人： DARLEY JESSE C , PYTEL STANLEY F , ZIEGLER JOHN S , MOY YEI F , RODENKIRCH DOUGLAS S
IPC分类号： B65D39/00 , B65D39/08
摘要： A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

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