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1. 发明授权

US08221409B2 Thermally insulated irrigation catheter assembly 有权
标题翻译：绝热冲洗导管组件
公开(公告)号：US08221409B2
公开(公告)日：2012-07-17
申请号：US11962600
申请日：2007-12-21
申请人： Hong Cao , Huisun Wang
发明人： Hong Cao , Huisun Wang
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00083 , A61B2018/00101 , A61B2218/002
摘要： The present invention relates to ablation electrode assemblies. The present invention further relates to an insulated irrigated ablation electrode assembly. The insulated irrigated ablation electrode assembly of the present invention includes a proximal member, a distal member and an intermediate thermally insulating member. The proximal member includes a body portion defined by an outer surface, an inner cavity defined within the outer body portion, and at least one passageway that extends from the inner cavity to the outer surface of the body portion. The distal member of the electrode assembly includes a distal end. Moreover, the intermediate member of the electrode assembly is disposed between the proximal member and the distal member thereby thermally insulating the proximal member from the distal member.
摘要翻译：本发明涉及消融电极组件。本发明还涉及绝缘灌溉消融电极组件。本发明的绝缘灌溉消融电极组件包括近端构件，远侧构件和中间隔热构件。近端构件包括由外表面限定的主体部分，限定在外主体部分内的内腔以及从内腔延伸到主体部分的外表面的至少一个通道。电极组件的远端构件包括远端。此外，电极组件的中间构件设置在近端构件和远端构件之间，从而使近端构件与远端构件热绝缘。

2. 发明申请

US20080161795A1 Irrigated ablation catheter system with pulsatile flow to prevent thrombus 有权
标题翻译：灌注式消融导管系统具有脉动流量，可预防血栓
公开(公告)号：US20080161795A1
公开(公告)日：2008-07-03
申请号：US11646275
申请日：2006-12-28
申请人： Huisun Wang , Jeremy D. Dando , Hong Cao
发明人： Huisun Wang , Jeremy D. Dando , Hong Cao
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00577 , A61B2218/002
摘要： The invention relates to an ablation catheter which controls the temperature and reduces the coagulation of biological fluids on an electrode of a catheter, prevents the impedance rise of tissue in contact with the electrode, and maximizes the potential energy transfer to the tissue, thereby allowing an increase in the lesion size produced by the ablation. The electrode includes passages positioned to allow saline flow out of an inner cavity of the electrode. This fluid flow is pulsatile to increase turbulence, reducing areas of stagnant flow, and produces a desired cooling effect.
摘要翻译：本发明涉及一种消融导管，其控制温度并减少导管电极上生物流体的凝结，防止与电极接触的组织的阻抗上升，并使能量传递到组织最大化，从而允许增加消融产生的病变大小。电极包括定位成允许盐水从电极的内腔流出的通道。这种流体流动是脉动的，以增加湍流，减少滞留流动的面积，并产生所需的冷却效果。

3. 发明授权

US08460285B2 Ablation catheter electrode having multiple thermal sensors and method of use 有权
公开(公告)号：US08460285B2
公开(公告)日：2013-06-11
申请号：US11647282
申请日：2006-12-29
申请人： Huisun Wang , Hong Cao , Jeremy D. Dando
发明人： Huisun Wang , Hong Cao , Jeremy D. Dando
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B18/14 , A61B2018/00011 , A61B2018/00023 , A61B2018/00577 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , Y10T29/49117
摘要： The invention relates to electrodes used in ablation catheter devices, where the electrodes contain two or more thermal sensors at different positions within the electrode that are capable of detecting temperature differences along the external surface of the electrode. In preferred embodiments, the thermal sensors are separated by one or more thermal insulating members and the thermal sensors are positioned near the external surface of the electrode at about the same distance from the end of the electrode, so that temperature measurements can indicate the position of the electrode with respect to the tissue desired to be ablated.

4. 发明申请

US20080161794A1 Irrigated ablation catheter having a pressure sensor to detect tissue contact 有权
标题翻译：灌注消融导管具有检测组织接触的压力传感器
公开(公告)号：US20080161794A1
公开(公告)日：2008-07-03
申请号：US11646270
申请日：2006-12-28
申请人： Huisun Wang , Hong Cao
发明人： Huisun Wang , Hong Cao
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2090/065 , A61B2218/002
摘要： The invention relates to an irrigated ablation catheter that has a pressure sensor to determine tissue contact as well as methods of using the same. The irrigated ablation catheter contains fluid tubing, an electrode with passages and a lumen and a pressure sensor located inside the lumen of the electrode. In some embodiments, a cooling fluid, such as saline, is passed through the catheter.
摘要翻译：本发明涉及一种具有确定组织接触的压力传感器的灌洗消融导管及其使用方法。灌注消融导管包含流体管，具有通道的电极和内腔，位于电极内腔内的压力传感器。在一些实施例中，诸如盐水的冷却流体通过导管。

5. 发明申请

US20080161797A1 Ablation catheter electrode having multiple thermal sensors and method of use 有权
标题翻译：消融导管电极具有多个热传感器和使用方法
公开(公告)号：US20080161797A1
公开(公告)日：2008-07-03
申请号：US11647282
申请日：2006-12-29
申请人： Huisun Wang , Hong Cao , Jeremy D. Dando
发明人： Huisun Wang , Hong Cao , Jeremy D. Dando
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B18/14 , A61B2018/00011 , A61B2018/00023 , A61B2018/00577 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , Y10T29/49117
摘要： The invention relates to electrodes used in ablation catheter devices, where the electrodes contain two or more thermal sensors at different positions within the electrode that are capable of detecting temperature differences along the external surface of the electrode. In preferred embodiments, the thermal sensors are separated by one or more thermal insulating members and the thermal sensors are positioned near the external surface of the electrode at about the same distance from the end of the electrode, so that temperature measurements can indicate the position of the electrode with respect to the tissue desired to be ablated.
摘要翻译：本发明涉及消融导管装置中使用的电极，其中电极在电极内的不同位置包含能够检测沿着电极外表面的温度差的两个或多个热传感器。在优选实施例中，热传感器被一个或多个绝热构件隔开，并且热传感器位于与电极端部大约相同距离处的电极的外表面附近，使得温度测量可以指示位置电极相对于希望烧蚀的组织。

6. 发明授权

US08690870B2 Irrigated ablation catheter system with pulsatile flow to prevent thrombus 有权
标题翻译：灌注式消融导管系统具有脉动流量，可预防血栓
公开(公告)号：US08690870B2
公开(公告)日：2014-04-08
申请号：US11646275
申请日：2006-12-28
申请人： Huisun Wang , Jeremy D. Dando , Hong Cao
发明人： Huisun Wang , Jeremy D. Dando , Hong Cao
IPC分类号： A61B18/04 , A61B18/18
CPC分类号： A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00577 , A61B2218/002
摘要： The invention relates to an ablation catheter which controls the temperature and reduces the coagulation of biological fluids on an electrode of a catheter, prevents the impedance rise of tissue in contact with the electrode, and maximizes the potential energy transfer to the tissue, thereby allowing an increase in the lesion size produced by the ablation. The electrode includes passages positioned to allow saline flow out of an inner cavity of the electrode. This fluid flow is pulsatile to increase turbulence, reducing areas of stagnant flow, and produces a desired cooling effect.
摘要翻译：本发明涉及一种消融导管，其控制温度并减少导管电极上生物流体的凝结，防止与电极接触的组织的阻抗上升，并使能量传递到组织最大化，从而允许增加消融产生的病变大小。电极包括定位成允许盐水从电极的内腔流出的通道。这种流体流动是脉动的，以增加湍流，减少滞留流动的面积，并产生所需的冷却效果。

7. 发明授权

US07591816B2 Irrigated ablation catheter having a pressure sensor to detect tissue contact 有权
标题翻译：灌注消融导管具有检测组织接触的压力传感器
公开(公告)号：US07591816B2
公开(公告)日：2009-09-22
申请号：US11646270
申请日：2006-12-28
申请人： Huisun Wang , Hong Cao
发明人： Huisun Wang , Hong Cao
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2090/065 , A61B2218/002
摘要： The invention relates to an irrigated ablation catheter that has a pressure sensor to determine tissue contact as well as methods of using the same. The irrigated ablation catheter contains fluid tubing, an electrode with passages and a lumen and a pressure sensor located inside the lumen of the electrode. In some embodiments, a cooling fluid, such as saline, is passed through the catheter.
摘要翻译：本发明涉及一种具有确定组织接触的压力传感器的灌洗消融导管及其使用方法。灌注消融导管包含流体管，具有通道的电极和内腔，位于电极内腔内的压力传感器。在一些实施例中，诸如盐水的冷却流体通过导管。

8. 发明授权

US10130418B2 Irrigated ablation electrode having smooth edges to minimize tissue char 有权
公开(公告)号：US10130418B2
公开(公告)日：2018-11-20
申请号：US12346634
申请日：2008-12-30
申请人： Huisun Wang , Sacha Hall
发明人： Huisun Wang , Sacha Hall
IPC分类号： A61B18/14 , A61B18/00
摘要： The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002″ to about 0.008″.

9. 发明授权

US09408694B2 Tip for medical implant delivery system 有权
标题翻译：医疗植入物输送系统的提示
公开(公告)号：US09408694B2
公开(公告)日：2016-08-09
申请号：US13211447
申请日：2011-08-17
申请人： Huisun Wang , Valerie J. Glazier
发明人： Huisun Wang , Valerie J. Glazier
IPC分类号： A61F2/24 , A61F2/966
CPC分类号： A61F2/2436 , A61F2/2433 , A61F2/966 , A61F2250/0018 , A61F2250/0019
摘要： A delivery system for delivering and deploying a medical implant, such as a prosthetic heart valve, includes an elongated support member, a sheath, and a tip. The sheath is movable relative to the elongated support member between a distal position overlying the medical implant and a proximal position exposing the medical implant for release from the delivery system. The tip is attached to the elongated support member and is positioned at a distal end of the sheath when the sheath is in the distal position. The tip has a compressed condition and an expanded condition, and a maximum diameter in the expanded condition that is larger than the outer diameter of the sheath.
摘要翻译：用于递送和部署诸如假体心脏瓣膜的医疗植入物的递送系统包括细长的支撑构件，护套和尖端。护套可以在覆盖医疗植入物的远侧位置和暴露医疗植入物以远离输送系统的近端位置之间相对于细长支撑构件移动。当护套处于远侧位置时，尖端附接到细长的支撑构件并且定位在护套的远端。尖端具有压缩状态和膨胀状态，并且膨胀状态中的最大直径大于护套的外径。

10. 发明授权

US08778019B2 Staged deployment devices and method for transcatheter heart valve delivery 有权
标题翻译：分期部署装置和经导管心脏瓣膜输送的方法
公开(公告)号：US08778019B2
公开(公告)日：2014-07-15
申请号：US13234782
申请日：2011-09-16
申请人： Bradley Charles Knippel , Huisun Wang , Ralph Joseph Thomas , Jacob John Daly
发明人： Bradley Charles Knippel , Huisun Wang , Ralph Joseph Thomas , Jacob John Daly
IPC分类号： A61F2/84 , A61F2/24 , A61F2/966
CPC分类号： A61F2/2436 , A61F2/95 , A61F2/962 , A61F2/966 , A61F2002/9517 , A61F2002/9534
摘要： A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve.
摘要翻译：用于可折叠心脏瓣膜的递送装置包括操作手柄和导管组件。操作手柄包括限定其中的移动空间的框架，可在移动空间内沿纵向方向移动的滑架组件和具有锁定和解锁状态的联接器，联接器可操作地连接到滑架组件以与其一起运动。导管组件包括轴，围绕该轴限定了阀接收室，所述轴可操作地连接到框架或托架组件中的一个，以及可操作地连接到托架组件的远侧护套，用于在托架组件之间运动，该封闭状态适于将阀门保持在隔室中，并且适于完全展开阀门的打开状态。

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