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1. 发明授权

US07226412B2 Endoscope system using normal light and fluorescence 有权
标题翻译：内窥镜系统使用正常光和荧光
公开(公告)号：US07226412B2
公开(公告)日：2007-06-05
申请号：US10853846
申请日：2004-05-25
申请人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana , Kazuhiro Gono
发明人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana , Kazuhiro Gono
IPC分类号： A61B1/05 , A61B1/06
CPC分类号： A61B1/00059 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/045 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B5/0071 , A61B5/0084
摘要： An endoscope system in accordance with an embodiment of the present invention includes an endoscope with a monochrome image pickup device for capturing reflected light and fluorescence from the body cavity, an excitation light cut filter which is installed in front of the image pickup device for shielding excitation light, and an endoscope ID which includes information on the type of the endoscope. A light source unit includes a first switching filter that irradiates light including excitation light for a fluorescent image mode and a filter for generating continuous light for a normal-light image mode. The filters switch based between the fluorescent image mode and the normal-light image mode. A second switching filter with a limiting filter that limits certain wavelengths of excitation light of the first switching filter is provided. The limiting filters are switched according to the endoscope ID or observation state in the fluorescence mode. The excitation light cut filter shields excitation light generated by the first and second filters.
摘要翻译：根据本发明的实施例的内窥镜系统包括：内窥镜，具有用于从体腔捕获反射光和荧光的单色图像拾取装置，安装在用于屏蔽激励的图像拾取装置的前方的激发截止滤光器光和内窥镜ID，其包括关于内窥镜的类型的信息。光源单元包括照射包括用于荧光图像模式的激发光的光的第一切换滤光器和用于产生用于正常光图像模式的连续光的滤光器。滤光片基于荧光图像模式和普通光图像模式之间切换。提供了具有限制第一开关滤波器的某些波长的激发光的限制滤波器的第二开关滤波器。根据荧光模式中的内窥镜ID或观察状态来切换限制滤光片。激发光截止滤光器屏蔽由第一和第二滤光器产生的激发光。

2. 发明授权

US07172553B2 Endoscope system using normal light and fluorescence 有权
标题翻译：内窥镜系统使用正常光和荧光
公开(公告)号：US07172553B2
公开(公告)日：2007-02-06
申请号：US10146389
申请日：2002-05-14
申请人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana , Kazuhiro Gono
发明人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana , Kazuhiro Gono
IPC分类号： A61B1/06 , A61B6/00
CPC分类号： A61B1/00059 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/045 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B5/0071 , A61B5/0084
摘要： In the light source unit 3A, a switching filter section 14, which can switch the RGB filter for normal-light observation and a filter for fluorescent observation on the optical path, is installed in front of the lamp 12, where if the fluorescent image mode is selected, the excitation light in a part of the blue wavelength band is supplied to the electronic endoscope 2A, and the excitation light reflected by the subject side is shielded by the excitation light cut filter 27 in front of the CCD 28 so as to obtain the fluorescent image, and also the signal of the fluorescent image and the signals of the two reflected light images which are set in a predetermined wavelength band are passed through the image processing circuit 38, where a matrix circuit for appropriately allocating the color signals of the R, G and B channels is installed, and as a result, the images can be displayed on the monitor 5 in pseudo-colors in hues which allow easy identification of a normal tissue and a pathologically affected tissue.
摘要翻译：在光源单元3A中，在灯12的前方安装可以切换用于普通光观察的RGB滤光器的开关滤波器部分14和用于荧光观察的滤光器，其中如果荧光图像选择蓝色波长带的一部分中的激发光被供给到电子内窥镜2A，并且由CCD 28反射的激励光被CCD28前方的激发光截止滤光器27遮蔽，从而以获得荧光图像，并且将荧光图像的信号和设置在预定波长带中的两个反射光图像的信号通过图像处理电路38，其中用于适当地分配颜色信号的矩阵电路安装了R，G和B通道，结果，图像可以以色调的伪色显示在监视器5上，这允许容易地识别正常组织和病态在逻辑上影响组织。

3. 发明授权

US07658710B2 Endoscope system using normal light and fluorescence 有权
标题翻译：内窥镜系统使用正常光和荧光
公开(公告)号：US07658710B2
公开(公告)日：2010-02-09
申请号：US11611929
申请日：2006-12-18
申请人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana , Kazuhiro Gono
发明人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana , Kazuhiro Gono
IPC分类号： A61B1/045
CPC分类号： A61B1/00059 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/045 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B5/0071 , A61B5/0084
摘要： An endoscope system includes a light source for supplying three narrow wavelength bands including one wavelength band for exciting fluorescence, an excitation light cut filter for transmitting light having a wavelength greater than either 470 nm or 490 nm, and an image capturing unit for capturing the light transmitted by the excitation light cut filter and outputting three wavelength band signals corresponding to the three narrow wavelength bands of the light source. Also included are first, second and third frame memories for inputting and storing the three wavelength band signals, respectively, and first, second and third output ends for outputting first, second and third color signals, respectively, to a monitor for displaying an image. An image processor receives signals from the first, second and third frame memories respectively and selects among the first output end, the second output end and third output end for outputting the received signals to the monitor.
摘要翻译：一种内窥镜系统，包括用于提供包括用于激发荧光的一个波长带的三个窄波长带的光源，用于透射波长大于470nm或490nm的光的激发截止滤光器和用于捕获光的图像捕获单元由激发光截止滤波器传输并输出对应于光源的三个窄波长带的三个波长带信号。还包括用于分别输入和存储三个波长带信号的第一，第二和第三帧存储器，以及分别将第一，第二和第三颜色信号输出到用于显示图像的监视器的第一，第二和第三输出端。图像处理器分别从第一，第二和第三帧存储器接收信号，并在第一输出端，第二输出端和第三输出端之间进行选择，以将接收的信号输出到监视器。

4. 发明授权

US07204803B2 Endoscope device, endoscope and image processing device for endoscope 有权
标题翻译：内窥镜装置，内窥镜及内窥镜用图像处理装置
公开(公告)号：US07204803B2
公开(公告)日：2007-04-17
申请号：US10647405
申请日：2003-08-25
申请人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana
发明人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana
IPC分类号： A61B1/04
CPC分类号： A61B1/045 , A61B1/00009 , A61B1/00059 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B5/0071 , A61B5/0084 , H04N2005/2255 , Y10S600/921
摘要： An image processing device for an endoscope, wherein a wavelength band filter for shielding at least a part of the blue wavelength band is disposed in front of an image pickup element built into the endoscope, for image processing the signal output by said image pickup element includes means for generating color image signals whilst switching between a normal-light image mode using white light and a fluorescence image mode including fluorescence information and adjusting means for adjusting the gain of a prescribed color signal of said color image signals.
摘要翻译：一种用于内窥镜的图像处理装置，其中用于屏蔽蓝色波长带的至少一部分的波长带滤波器被布置在内置于内窥镜中的图像拾取元件的前面，用于对由所述图像拾取元件输出的信号进行图像处理包括用于在使用白光的正常光图像模式和包括荧光信息的荧光图像模式之间切换时产生彩色图像信号的装置和用于调节所述彩色图像信号的规定颜色信号的增益的调整装置。

5. 发明授权

US06960165B2 Endoscope with a single image pick-up element for fluorescent and normal-light images 有权
标题翻译：具有用于荧光和正常光图像的单个图像拾取元件的内窥镜
公开(公告)号：US06960165B2
公开(公告)日：2005-11-01
申请号：US10145966
申请日：2002-05-14
申请人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana
发明人： Hitoshi Ueno , Takeshi Ozawa , Kazunari Nakamura , Isami Hirao , Hiroshi Ibe , Koichi Yoshimitsu , Yuichi Morizane , Mamoru Kaneko , Shunya Akimoto , Masaki Terakubo , Katsuichi Imaizumi , Nobuyuki Doguchi , Sakae Takehana
IPC分类号： A61B1/04 , A61B1/045 , A61B5/00 , A61B1/06 , A61B6/00
CPC分类号： A61B1/045 , A61B1/00009 , A61B1/00059 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B5/0071 , A61B5/0084 , H04N2005/2255 , Y10S600/921
摘要： In a light source unit, a switchable filter section in which an RGB filter and a fluorescence observation filter can be shifted into the light path is disposed in front of a lamp. When fluorescence image mode is selected, excitation light in a part of the wavelength band of the blue wavelength band is supplied to an electronic endoscope, and the excitation light which is reflected by the subject is shielded by an excitation light shielding filter situated in front of a CCD, whereby a fluorescence image can be obtained. On the other hand, if normal-light image mode is selected, then R, G, B light is supplied sequentially, and even under illumination of B light, the color component image in the wavelength bands which are not shielded by the excitation light shielding filter are captured, thereby yielding a normal-light image also, and hence making it possible to capture both a fluorescence image and a normal-light image by means of a single image pickup element.
摘要翻译：在光源单元中，在灯的前面设置有可以将RGB滤光器和荧光观察滤光器移入光路的可切换滤光器部。当选择荧光图像模式时，蓝色波长带的波长带的一部分中的激发光被提供给电子内窥镜，被被摄体反射的激发光被位于前方的激发光屏蔽滤光器屏蔽 CCD，由此可以获得荧光图像。另一方面，如果选择了常规光图像模式，则顺序地提供R，G，B光，并且即使在B光照明下，也不会被激发光屏蔽屏蔽的波长带中的分色图像过滤器被捕获，从而也产生正常光图像，因此可以通过单个图像拾取元件捕获荧光图像和正常光图像。

6. 发明授权

US06772003B2 Endoscope apparatus 有权
标题翻译：内窥镜装置
公开(公告)号：US06772003B2
公开(公告)日：2004-08-03
申请号：US10207697
申请日：2002-07-29
申请人： Mamoru Kaneko , Akira Hasegawa , Katsuichi Imaizumi , Shunya Akimoto , Naoki Miura , Katsuya Ono , Hideyuki Takaoka , Kazuhiro Gono , Junichi Nozawa
发明人： Mamoru Kaneko , Akira Hasegawa , Katsuichi Imaizumi , Shunya Akimoto , Naoki Miura , Katsuya Ono , Hideyuki Takaoka , Kazuhiro Gono , Junichi Nozawa
IPC分类号： A61B600
CPC分类号： G02B23/2407 , A61B1/0005 , A61B1/00096 , A61B1/05 , A61B1/0638 , A61B1/0646 , G02B21/22
摘要： A general-light observation light image can be obtained by illuminating the polarized frame sequence light or polarized white light, for example. In addition, a parallel polarized component and a vertical polarized component with respect to a polarizing direction of illuminating light, which is polarized in a specific direction are captured. Then, image data, which is a difference between both of the polarized component is calculated and is displayed in a display device. Thus, a scattered light component in a living-body tissue surface side can be extracted with good S/N, which can improve the diagnosis functionality.
摘要翻译：例如，可以通过照射偏振帧序列光或偏振白光来获得普通光观察光图像。此外，捕获相对于沿特定方向极化的照明光的偏振方向的平行偏振分量和垂直偏振分量。然后，计算两个偏振分量之间的差异的图像数据，并将其显示在显示装置中。因此，可以以良好的S / N提取生物体组织表面侧的散射光分量，这可以提高诊断功能。

7. 发明授权

US07324674B2 Image processing device for fluorescence observation 有权
标题翻译：用于荧光观察的图像处理装置
公开(公告)号：US07324674B2
公开(公告)日：2008-01-29
申请号：US10601496
申请日：2003-06-23
申请人： Takeshi Ozawa , Katsuichi Imaizumi , Shunya Akimoto , Kazuhiro Gono
发明人： Takeshi Ozawa , Katsuichi Imaizumi , Shunya Akimoto , Kazuhiro Gono
IPC分类号： G06K9/00
CPC分类号： A61B1/0638 , A61B1/00009 , A61B1/0005 , A61B1/00186 , A61B1/043 , A61B1/0646 , A61B1/0669
摘要： An image processing device having a very straightforward construction, for obtaining an image in which normal tissue and diseased tissue are easy to identify, comprises: an image synthesizing section that generates a synthesized image by synthesizing an image signal of reflected light image produced by illumination light obtained by illuminating body tissue with illumination light and an image signal of a fluorescent image obtained by illuminating the body tissue with excitation light; and a gain adjustment section that adjusts the gain of the image signal of the reflected light image and/or the image signal of the fluorescent image such that the boundary of the hues of the normal tissue and diseased tissue found from the optical characteristics of the respective tissues is contained in a predetermined range with respect to a prescribed standard chromaticity diagram, depending on whether the body tissue that is displayed on the synthesized image generated by the image synthesizing section is normal tissue or diseased tissue.
摘要翻译：一种具有非常简单的结构的图像处理装置，用于获得容易识别正常组织和病变组织的图像，包括：图像合成部，其通过合成由照明光产生的反射光图像的图像信号来生成合成图像通过用照明光照射身体组织获得的图像信号和通过用激发光照射身体组织而获得的荧光图像的图像信号; 以及增益调整部，其调整反射光图像的图像信号的增益和/或荧光图像的图像信号，使得从各自的光学特性发现正常组织和患病组织的色调的边界根据由图像合成部生成的合成图像上显示的身体组织是正常组织还是患病组织，组织相对于规定的标准色度图包含在预定范围内。

8. 发明授权

US08049777B2 Insertion support system for specifying a location of interest as an arbitrary region and also appropriately setting a navigation leading to the specified region 有权
标题翻译：插入支持系统，用于将感兴趣的位置指定为任意区域，并且还适当地设置导向指定区域的导航
公开(公告)号：US08049777B2
公开(公告)日：2011-11-01
申请号：US11412397
申请日：2006-04-27
申请人： Shunya Akimoto , Junichi Ohnishi , Fumihiro Asano , Hiroshi Moriya , Koichi Yamazaki , Takashi Ishida
发明人： Shunya Akimoto , Junichi Ohnishi , Fumihiro Asano , Hiroshi Moriya , Koichi Yamazaki , Takashi Ishida
IPC分类号： A62B1/04
CPC分类号： A61B1/2676 , A61B5/06 , A61B6/00 , A61B90/10
摘要： According to an insertion support system of the present invention, when a biopsy area is specified at a periphery of the bronchi, the barycenter of the biopsy area is extracted. A circle centering on the barycenter is determined as a search area. The search area is expanded until the bronchi are located within the search area. A point in the search area to which the bronchi first reach is determined as an end point. A first route choice connecting the end point and a start point is determined. If the first route choice has not been registered yet, the first route choice is registered as a first registered route. Accordingly, a location of interest can be specified as an arbitrary region, and navigation leading to the specified region is appropriately set.
摘要翻译：根据本发明的插入支撑系统，当在支气管周边指定活检区域时，提取活检区域的重心。以重心为中心的圆确定为搜索区域。搜索区域扩展到支气管位于搜索区域内。支气管首先到达的检索区域的一个点被确定为终点。确定连接终点和起始点的第一路线选择。如果第一路线选择尚未登记，则将第一路线选择登记为第一登记路线。因此，可以将感兴趣的位置指定为任意区域，并且适当地设定导向指定区域的导航。

9. 发明申请

US20050020878A1 Endoscope 有权
标题翻译：内窥镜
公开(公告)号：US20050020878A1
公开(公告)日：2005-01-27
申请号：US10498155
申请日：2003-07-31
申请人： Junichi Ohnishi , Shunya Akimoto , Eiichi Kobayashi
发明人： Junichi Ohnishi , Shunya Akimoto , Eiichi Kobayashi
IPC分类号： A61B1/04 , A61B1/267 , A61B1/00
CPC分类号： A61B1/00147 , A61B1/00009 , A61B1/0005 , A61B1/042 , A61B1/2676
摘要： In an endoscope device 1 in accordance with the present invention, a navigation screen 51 is displayed. The navigation screen 51 includes: an endoscopic live image display area 52 in which a live image produced by a bronchoscope 2 is displayed; a VBS image display area 53 in which a VBS image is displayed; and a thumbnail VBS image area 54 in which images constructed by reducing VBS images that represent all branch points on a route are displayed as thumbnail VBS images representing branch points. Consequently, an endoscope can be reliably navigated to reach a target region using guide images that represent actual branch positions.
摘要翻译：在根据本发明的内窥镜装置1中，显示导航画面51。导航画面51包括：显示由支气管镜2产生的实时图像的内窥镜实时图像显示区域52; 显示VBS图像的VBS图像显示区域53; 以及缩略图VBS图像区域54，其中通过减少表示路线上的所有分支点的VBS图像构成的图像被显示为表示分支点的缩略图VBS图像。因此，可以使用代表实际分支位置的引导图像，可靠地导航内窥镜到达目标区域。

10. 发明申请

US20050272971A1 Medical treatment system, endoscope system, endoscope insert operation program, and endoscope device 审中-公开
标题翻译：医疗系统，内窥镜系统，内窥镜插入操作程序和内窥镜装置
公开(公告)号：US20050272971A1
公开(公告)日：2005-12-08
申请号：US10523423
申请日：2003-08-29
申请人： Junichi Ohnishi , Shunya Akimoto , Kunihide Kaji , Eiichi Kobayashi , Akito Saito , Takao Shibasaki , Taiji Mine
发明人： Junichi Ohnishi , Shunya Akimoto , Kunihide Kaji , Eiichi Kobayashi , Akito Saito , Takao Shibasaki , Taiji Mine
IPC分类号： A61B1/018 , A61B1/04 , A61B1/267 , A61B1/00
CPC分类号： A61B34/20 , A61B1/00009 , A61B1/00048 , A61B1/0005 , A61B1/00089 , A61B1/00101 , A61B1/018 , A61B1/042 , A61B1/2676 , A61B5/065 , A61B5/068 , A61B2090/061 , A61B2090/067
摘要： An analyzing unit 9 is connected to an inserting-operation information collecting unit 5, an endoscope video output unit 6, and a processing device 2, and receives live inserting-operation information and endoscope image, standard inserting-operation information as stored information, and an endoscope image correlated therewith (endoscope image which is obtained by picking up an image of a sample at the position of a distal-end portion of an inserting portion detected based on the inserting-operation information). The analyzing unit 9 collects in real time the inserting-operation information and the endoscope image from the inserting-operation information collecting unit 5 and the endoscope video output unit 6 under the bronchoscope operation of an operator. Further, the analyzing unit 9 sequentially analyzes the collected inserting-operation information and endoscope image by comparing with the standard inserting-operation information and endoscope image correlated with the inserting-operation information, which are stored in a storing unit 2A of the processing device 2, outputs an analysis result to a notifying unit 10, and monitors the inserting operation of the endoscope inserting portion performed by the operator.
摘要翻译：分析单元9连接到插入操作信息收集单元5，内窥镜视频输出单元6和处理设备2，并且接收实时插入操作信息和内窥镜图像，标准插入操作信息作为存储信息，以及与其相关联的内窥镜图像（通过在基于插入操作信息检测出的插入部的前端部的位置拾取样本的图像而获得的内窥镜图像）。分析单元9在操作者的支气管镜操作下从插入操作信息收集单元5和内窥镜视频输出单元6实时收集插入操作信息和内窥镜图像。此外，分析单元9通过与存储在处理设备的存储单元2A中的插入操作信息相关的标准插入操作信息和内窥镜图像进行比较，顺序地分析收集的插入操作信息和内窥镜图像如图2所示，将分析结果输出到通知单元10，并且监视由操作者进行的内窥镜插入部的插入操作。

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