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1. 发明授权

US6166168A Application of sulfone, ketone and ester containing polyalkyl ether units to medical materials 有权
标题翻译：在医用材料中应用含有聚烷基醚单元的砜，酮和酯
公开(公告)号：US6166168A
公开(公告)日：2000-12-26
申请号：US271292
申请日：1999-03-17
申请人： Hiroaki Kuwahara , Takeyuki Kawaguchi , Satoru Ohmori , Shunichi Matsumura
发明人： Hiroaki Kuwahara , Takeyuki Kawaguchi , Satoru Ohmori , Shunichi Matsumura
IPC分类号： B01D67/00 , B01D71/48 , B01D71/52 , B01D71/68 , B01D71/80 , C08G65/40 , C08G75/23 , C08L67/02 , C08L71/00 , C08L71/02 , C08L81/06 , C08L33/14 , C08G2/00 , C08G75/00 , C08L41/00
CPC分类号： B01D67/0088 , B01D71/48 , B01D71/52 , B01D71/68 , B01D71/76 , B01D71/80 , C08G65/4012 , C08G75/23 , C08L67/025 , C08L71/00 , C08L71/02 , C08L81/06 , C08L2205/05 , Y10S525/906 , C08L2666/02
摘要： A novel polyalkyl ether/polyaryl ether sulfone or ketone copolymer and a specific polyether ester copolymer are useful for producing a medical material to be used to contact the blood; and methods for producing the medical material comprising said polyalkyl ether/polyaryl ether sulfone or ketone copolymer or a specific polyether ester copolymer.
摘要翻译：新型聚烷基醚/聚芳基醚砜或酮共聚物和特定的聚醚酯共聚物可用于生产用于接触血液的医用材料; 以及包含所述聚烷基醚/聚芳基醚砜或酮共聚物或特定聚醚酯共聚物的医疗材料的制造方法。

2. 发明授权

US5969082A Application of sulfone, ketone and ester containing polyalkyl ether units to medical materials 失效
公开(公告)号：US5969082A
公开(公告)日：1999-10-19
申请号：US772981
申请日：1996-12-23
申请人： Hiroaki Kuwahara , Takeyuki Kawaguchi , Satoru Ohmori , Shunichi Matsumura
发明人： Hiroaki Kuwahara , Takeyuki Kawaguchi , Satoru Ohmori , Shunichi Matsumura
IPC分类号： B01D67/00 , B01D71/48 , B01D71/52 , B01D71/68 , B01D71/80 , C08G65/40 , C08G75/23 , C08L67/02 , C08L71/00 , C08L71/02 , C08L81/06 , C08G2/00 , C08G75/00
CPC分类号： B01D67/0088 , B01D71/76 , B01D71/80 , C08G65/4012 , C08G75/23 , C08L67/025 , C08L71/00 , C08L71/02 , C08L81/06 , B01D71/48 , B01D71/52 , B01D71/68 , C08L2205/05 , Y10S525/906
摘要： A novel polyalkyl ether/polyaryl ether sulfone or ketone copolymer and a specific polyether ester copolymer are useful for producing a medical material to be used to contact the blood; and methods for producing the medical material comprising said polyalkyl ether/polyaryl ether sulfone or ketone copolymer or a specific polyether ester copolymer.

3. 发明授权

US5814179A Process for producing a blood dialyzer 失效
标题翻译：生产血液透析器的方法
公开(公告)号：US5814179A
公开(公告)日：1998-09-29
申请号：US654312
申请日：1996-05-28
申请人： Satoru Ohmori , Hironori Matsuda , Takahiro Daido , Takeyuki Kawaguchi
发明人： Satoru Ohmori , Hironori Matsuda , Takahiro Daido , Takeyuki Kawaguchi
IPC分类号： A61M1/18 , B01D63/02 , B01D65/02 , B01D65/06 , B01D67/00 , B32B31/00
CPC分类号： B01D67/0095 , B01D63/021 , B01D65/02 , B01D65/022 , B01D2321/00
摘要： A blood dialyzer is produced by a process in which a plurality of artificial composite fibers having core portions consisting of a water-insoluble core liquid and surrounded by sheath portions consisting of a fiber-forming polymer are subjected to a removal of almost all of the core liquid; the resultant hollow fibers are bundled; the hollow fiber bundle is packed in a cylindrical case having open end; end portions of spaces left between the hollow fibers peripheries and between the hollow fibers and the inside surface of the cylindrical case are sealed with a bonding material, to fix the hollow fiber bundle to the cylindrical case at the end portions thereof; and the hollow fibers in the cylindrical case are cleaned with a cleaning liquid comprising at least one aliphatic monohydric alcohol having 3 to 8 carbon atoms.
摘要翻译：通过这样的方法制造血液透析器，其中将具有由水不溶性核心液体构成的核心部分并由被成纤聚合物组成的鞘部分包围的多个人造复合纤维除去几乎所有的核心液体; 所得中空纤维束缚; 中空纤维束被包装在具有开口端的圆筒形壳体中; 在中空纤维周边之间以及中空纤维与圆筒形壳体的内表面之间留下的空间的端部用接合材料密封，以将中空纤维束固定在其端部处的圆筒形壳体上; 并且用包含至少一种具有3-8个碳原子的脂族一元醇的清洗液清洁圆筒形壳体中的中空纤维。

4. 发明授权

US06433054B1 Gel-form pressure-sensitive adhesive, and adhesive material and adhesive medicinal preparation both containing the same 失效
标题翻译：凝胶型压敏粘合剂，以及含有相同材料的粘合剂和粘合剂制剂
公开(公告)号：US06433054B1
公开(公告)日：2002-08-13
申请号：US09508765
申请日：2000-03-16
申请人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Susumu Maruo , Hiroaki Kuwahara , Takanori Miyoshi , Michio Iwai
发明人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Susumu Maruo , Hiroaki Kuwahara , Takanori Miyoshi , Michio Iwai
IPC分类号： C08K509
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7069 , A61L15/58 , C08G2170/40 , C08L31/00 , C08L33/00 , C08L67/025 , C08L71/02 , C08L75/04 , C08L2666/04 , C08L2666/14 , C08L2666/28 , C09J131/04 , C09J133/08 , C09J167/00 , C09J167/025 , C09J175/04 , C09J177/00 , C08L67/00 , C08L77/00
摘要： The gel adhesive of the present invention contains an elastomer component (A), a self-adhesive polymer component (B) compatible with the elastomer component (A), and a liquid component (C) compatible with the elastomer component (A) and the self-adhesive polymer (B), the liquid component (C) being held in a mixture of the elastomer component (A) and the self-adhesive polymer (B) without exuding, to form as a whole, a gel, and is useful for forming a self-adhesive layer of an adhesive material or a pharmaceutical-containing self-adhesive layer of an adhering pharmaceutical preparation, which layer is capable of being firmly adhered to a surface to be adhered, and particularly a body skin surface, and of being easily removed therefrom without leaving a portion of the layer on the adhered surface.
摘要翻译：本发明的凝胶粘合剂含有弹性体成分（A），与弹性体成分（A）相容的自粘聚合物成分（B）和与弹性体成分（A）相容的液体成分（C）和自粘聚合物（B），液体组分（C）保持在弹性体组分（A）和自粘聚合物（B）的混合物中而不渗出，从而形成凝胶，并且是有用的用于形成粘合剂材料的自粘合层或粘附药物制剂的含药物的自粘合层，该层能够牢固地粘附到待粘附的表面，特别是身体表皮表面，以及容易地从中去除，而不会在粘合表面上留下一部分层。

5. 发明授权

US4820649A Method and kit having layered device for detecting biological component by interference color 失效
标题翻译：具有用于通过干涉色检测生物成分的分层装置的方法和试剂盒
公开(公告)号：US4820649A
公开(公告)日：1989-04-11
申请号：US99906
申请日：1987-09-22
申请人： Takeyuki Kawaguchi , Takashi Shiro
发明人： Takeyuki Kawaguchi , Takashi Shiro
IPC分类号： G01N21/29 , G01N21/55 , G01N21/75 , G01N33/52 , G01N33/543 , G01N33/53 , G01N33/553
CPC分类号： G01N21/75 , G01N33/525 , G01N33/54366 , G01N21/29 , G01N21/55 , Y10S436/805 , Y10S436/808
摘要： A method for detecting a component of a biological system, which comprises contacting a biological component detecting device composed of a light reflecting substrate (I) substantially free from diffused reflection, a light interference layer (II) formed on the substrate (I), and a layer (III) of a substance for detecting said biological component provided at least in a region on the layer (II), with a solution presumed to contain the biological component to be detected, then forming a light-transmitting reflecting layer (IV) on its surface, and thereafter detecting the color of light interference or the brightness of the reflected light on the surface of the device.
摘要翻译：一种用于检测生物系统的部件的方法，包括使由基本上不含扩散反射的光反射基板（I）构成的生物成分检测装置，形成在基板（I）上的光干涉层（II）和用于检测至少在层（II）上的区域中提供的所述生物成分的物质层（III），其中假定含有要检测的生物成分的溶液，然后形成透光反射层（IV）在其表面上，然后检测装置的表面上的光干涉的颜色或反射光的亮度。

6. 发明授权

US4353802A Semipermeable composite membrane 失效
标题翻译：半透膜复合膜
公开(公告)号：US4353802A
公开(公告)日：1982-10-12
申请号：US86192
申请日：1979-10-18
申请人： Shigeyoshi Hara , Yuzuru Hayashi , Takeyuki Kawaguchi , Noriaki Sasaki , Yutaka Taketani , Hiroyoshi Minematsu
发明人： Shigeyoshi Hara , Yuzuru Hayashi , Takeyuki Kawaguchi , Noriaki Sasaki , Yutaka Taketani , Hiroyoshi Minematsu
IPC分类号： B01D61/08 , B01D69/12 , B01D71/40 , B01D71/44 , B01D71/48 , B01D71/52 , B01D71/60 , B01D71/66 , B01D71/82 , B01D13/00
CPC分类号： B01D71/60 , B01D69/125 , B01D71/44
摘要： A semipermeable composite membrane comprising a thin semipermeable film of a polymeric material deposited on one side of a microporous substrate, the polymeric material being prepared by crosslinking a soluble polymer containing at least 30 mole % of a recurring unit of the formula ##STR1## wherein all symbols are as defined herein, and having at least 0.5 milliequivalent, per gram of said polymer, of an amino group containing 1 or 2 active hydrogen atoms, with a polyfunctional compound containing at least two functional groups capable of reacting with the amino group having 1 or 2 active hydrogen atoms; and a process for preparing the same. The semipermeable composite membrane of this invention is especially useful for desalination of saline or brackish water by reverse osmosis.
摘要翻译：一种半透性复合膜，其包含沉积在微孔基材的一侧上的聚合材料的薄的半透膜，所述聚合物材料通过交联含有至少30摩尔％的式（IMAGE）的重复单元的可溶性聚合物制备，其中所有符号如本文所定义，并且每克所述聚合物具有至少0.5毫当量的含有1或2个活性氢原子的氨基，和具有至少两个能够与具有1个氨基的氨基反应的官能团的多官能化合物或2个活性氢原子; 及其制备方法。本发明的半透膜复合膜特别适用于通过反渗透脱盐盐水或微咸水。

7. 发明授权

US5658466A Method of sterilizing a blood dialyzer having semipermeable polymeric membranes by .gamma.-ray irradiation 失效
标题翻译：通过γ射线照射对具有半透性聚合物膜的血液透析器进行灭菌的方法
公开(公告)号：US5658466A
公开(公告)日：1997-08-19
申请号：US404311
申请日：1995-03-15
申请人： Takeyuki Kawaguchi , Hironori Matsuda , Masaaki Tsukioka , Takahiro Daido
发明人： Takeyuki Kawaguchi , Hironori Matsuda , Masaaki Tsukioka , Takahiro Daido
IPC分类号： A61L2/08 , B01D65/02 , A61L2/00
CPC分类号： A61L2/08 , B01D65/022 , B01D2321/28 , B01D2321/346
摘要： A blood dialyzer having semipermeable polymeric dialyzing membranes is sterilized by impregnating the dialyzing membranes, for example, dialyzing hollow fibers, with an aqueous solution of a .gamma.-ray-absorbent and water-soluble dihydric aliphatic alcohol and irradiating .gamma.-rays to the dialyzing membranes, to prevent the deterioration of the dialyzing membranes and the generation of ultraviolet-ray-absorbent substance in the dialyzing membrane.
摘要翻译：具有半透性聚合物透析膜的血液透析器通过用γ-射线吸收剂和水溶性二羟基脂肪醇的水溶液浸渍透析膜，例如透析中空纤维来灭菌，并将γ射线照射到透析膜，以防止透析膜的劣化和透析膜中的紫外线吸收物质的产生。

8. 发明授权

US4388189A Process for preparation of improved semipermeable composite membranes 失效
标题翻译：改良半透膜复合膜的制备方法
公开(公告)号：US4388189A
公开(公告)日：1983-06-14
申请号：US220081
申请日：1980-12-24
申请人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara
发明人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara
IPC分类号： B01D71/28 , B01D69/12 , B01D71/38 , B01D71/48 , B01D71/52 , B01D71/60 , B01D71/66 , B01D71/82 , B01D31/00
CPC分类号： B01D69/125 , B01D71/60
摘要： In a process for producing a semipermeable composite membrane which comprises forming on a microporous substrate a thin layer of a polymeric material comprising a polyamino polymer containing at least 1 milliequivalent, per gram of the polymer in the dry state, of active amino groups selected from primary amino groups and secondary amino groups, and thereafter interfacially crosslinking a surface portion of said thin layer with a crosslinking agent having at least two functional groups (a) capable of easily reacting with either the primary or secondary amino groups or both in said polymer; the improvement wherein(1) said polymeric material contains dispersed therein a polyfunctional compound having at least two functional groups (b) substantially incapable of reacting with the primary or secondary amino groups in said polymer at a temperature at which the interfacial crosslinking is carried out, but capable of reacting easily with either the primary or secondary amino groups or both in said polymer at a temperature at least 30.degree. C. higher than said crosslinking temperature, and(2) the interfacially crosslinked thin layer is heated to a temperature at which said polyfunctional compound reacts with the primary or secondary amino groups or both in said polymer.
摘要翻译：在一种制备半透膜复合膜的方法中，该方法包括在微孔基材上形成包含聚氨基聚合物的聚合物材料的薄层，所述聚合物材料含有至少1毫当量的每克干燥状态的聚合物，选自主要氨基和仲氨基，然后用具有至少两个能够容易地与所述聚合物中的伯或仲氨基反应的二官能团（a）的交联剂与所述薄层的表面部分进行界面交联; 改进之处在于（1）所述聚合材料含有分散有至少两个官能团的多官能化合物（b）在进行界面交联的温度下基本上不能与所述聚合物中的伯或仲氨基发生反应，但能够在高于所述交联温度的至少30℃的温度下容易地与所述聚合物中的伯或仲氨基或两者反应，和（2）将界面交联的薄层加热至所述多官能化合物与所述聚合物中的伯或仲氨基或两者反应。

9. 发明授权

US4265745A Permselective membrane 失效
标题翻译：选择膜
公开(公告)号：US4265745A
公开(公告)日：1981-05-05
申请号：US907194
申请日：1978-05-18
申请人： Takeyuki Kawaguchi , Yutaka Taketani , Yuzuru Hayashi , Tomoyoshi Ono , Koh Mori
发明人： Takeyuki Kawaguchi , Yutaka Taketani , Yuzuru Hayashi , Tomoyoshi Ono , Koh Mori
IPC分类号： B01D69/12 , B01D71/46 , B01D71/60 , C08G59/20 , C08G59/50 , B01D13/00
CPC分类号： C08G59/50 , B01D69/125 , B01D71/46 , B01D71/60 , C08G59/20
摘要： A permselective membrane comprising a thin permselective film of a polymeric material, said polymeric material being prepared by cross-linking a polyaddition product between a polyepoxy compound and a polyamino compound having at least two amino groups capable of reacting with epoxy groups with a polyfunctional compound selected from the group consisting of aromatic, heterocyclic and alicyclic compounds containing at least two functional groups selected from acid halide, sulfonyl halide, isocyanate and acid anhydride groups; and a process for producing the same. The permselective membrane of this invention is especially useful for desalination of saline or brackish water by reverse osmosis.
摘要翻译：一种选择性选择性膜，其包括聚合物材料的薄的选择性选择性膜，所述聚合物材料通过将多环氧化合物和具有至少两个能够与环氧基反应的氨基的多氨基化合物与多官能化合物反应选择的聚加成产物交联而制备由选自酰卤，磺酰卤，异氰酸酯和酸酐基团中的至少两个官能团的芳族，杂环和脂环族化合物组成; 及其制造方法。本发明的选择性选择性膜通过反渗透特别用于盐水或微咸水的脱盐。

10. 发明授权

US06291106B1 Electrolytic-solution-supporting polymer film and secondary battery 有权
标题翻译：电解液支撑聚合物膜和二次电池
公开(公告)号：US06291106B1
公开(公告)日：2001-09-18
申请号：US09314139
申请日：1999-05-19
申请人： Takahiro Daido , Takeyuki Kawaguchi
发明人： Takahiro Daido , Takeyuki Kawaguchi
IPC分类号： H01M618
CPC分类号： H01M10/052 , H01M2/16 , H01M2/162 , H01M2/1653 , H01M2/1666 , H01M2/1673 , H01M10/0525 , H01M10/0565 , H01M2300/0085
摘要： A high-strength, heat-resistant and high-safety electrolytic-solution-supporting polymer film which can be applied to secondary batteries typified by lithium and lithium ion secondary batteries and which has an ionic conductivity of at least 5×10−4 S/cm at 25° C., a puncture strength of at least 300 g and a mechanical heat resistance of at least 300° C.
摘要翻译：一种高强度，耐热，高安全性的电解液支撑聚合物膜，可应用于以锂和锂离子二次电池为代表的二次电池，其离子电导率至少为5×10 -4 S / cm 25℃，穿刺强度为至少300g，机械耐热性为至少300℃。

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