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1. 发明授权

US4265745A Permselective membrane 失效
标题翻译：选择膜
公开(公告)号：US4265745A
公开(公告)日：1981-05-05
申请号：US907194
申请日：1978-05-18
申请人： Takeyuki Kawaguchi , Yutaka Taketani , Yuzuru Hayashi , Tomoyoshi Ono , Koh Mori
发明人： Takeyuki Kawaguchi , Yutaka Taketani , Yuzuru Hayashi , Tomoyoshi Ono , Koh Mori
IPC分类号： B01D69/12 , B01D71/46 , B01D71/60 , C08G59/20 , C08G59/50 , B01D13/00
CPC分类号： C08G59/50 , B01D69/125 , B01D71/46 , B01D71/60 , C08G59/20
摘要： A permselective membrane comprising a thin permselective film of a polymeric material, said polymeric material being prepared by cross-linking a polyaddition product between a polyepoxy compound and a polyamino compound having at least two amino groups capable of reacting with epoxy groups with a polyfunctional compound selected from the group consisting of aromatic, heterocyclic and alicyclic compounds containing at least two functional groups selected from acid halide, sulfonyl halide, isocyanate and acid anhydride groups; and a process for producing the same. The permselective membrane of this invention is especially useful for desalination of saline or brackish water by reverse osmosis.
摘要翻译：一种选择性选择性膜，其包括聚合物材料的薄的选择性选择性膜，所述聚合物材料通过将多环氧化合物和具有至少两个能够与环氧基反应的氨基的多氨基化合物与多官能化合物反应选择的聚加成产物交联而制备由选自酰卤，磺酰卤，异氰酸酯和酸酐基团中的至少两个官能团的芳族，杂环和脂环族化合物组成; 及其制造方法。本发明的选择性选择性膜通过反渗透特别用于盐水或微咸水的脱盐。

2. 发明授权

US4260652A Preparation of permselective composite membrane 失效
标题翻译：选择性复合膜的制备
公开(公告)号：US4260652A
公开(公告)日：1981-04-07
申请号：US912547
申请日：1978-06-05
申请人： Yutaka Taketani , Yuzuru Hayashi , Takeyuki Kawaguchi , Tomoyoshi Ono , Ko Mori
发明人： Yutaka Taketani , Yuzuru Hayashi , Takeyuki Kawaguchi , Tomoyoshi Ono , Ko Mori
IPC分类号： B01D71/62 , C08G73/18 , B05D5/00 , C08J9/26 , C08L79/04
CPC分类号： C08G73/18 , B01D71/62 , Y10S524/909
摘要： A process and composition for producing a permselective composite membrane. The process comprises dissolving a specified imidazolone ring-containing aromatic polymer in an aqueous liquid medium containing a water-miscible amine having a pKa of more than 5.0 in a concentration of at least 5% by weight, coating the polymer solution on a microporous substrate, and drying the coating to form an ultrathin film on the substrate. The permselective composite membrane obtained is especially useful as a reverse osomsis membrane.
摘要翻译：用于制备渗透选择性复合膜的方法和组合物。该方法包括将含有咪唑啉酮环的芳族聚合物溶解在含有至少5重量％浓度的pKa大于5.0的水混溶性胺的含水液体介质中，将聚合物溶液涂布在微孔基材上，并干燥涂层以在基底上形成超薄膜。获得的选择性复合膜特别适用于反渗透膜。

3. 发明授权

US4353802A Semipermeable composite membrane 失效
标题翻译：半透膜复合膜
公开(公告)号：US4353802A
公开(公告)日：1982-10-12
申请号：US86192
申请日：1979-10-18
申请人： Shigeyoshi Hara , Yuzuru Hayashi , Takeyuki Kawaguchi , Noriaki Sasaki , Yutaka Taketani , Hiroyoshi Minematsu
发明人： Shigeyoshi Hara , Yuzuru Hayashi , Takeyuki Kawaguchi , Noriaki Sasaki , Yutaka Taketani , Hiroyoshi Minematsu
IPC分类号： B01D61/08 , B01D69/12 , B01D71/40 , B01D71/44 , B01D71/48 , B01D71/52 , B01D71/60 , B01D71/66 , B01D71/82 , B01D13/00
CPC分类号： B01D71/60 , B01D69/125 , B01D71/44
摘要： A semipermeable composite membrane comprising a thin semipermeable film of a polymeric material deposited on one side of a microporous substrate, the polymeric material being prepared by crosslinking a soluble polymer containing at least 30 mole % of a recurring unit of the formula ##STR1## wherein all symbols are as defined herein, and having at least 0.5 milliequivalent, per gram of said polymer, of an amino group containing 1 or 2 active hydrogen atoms, with a polyfunctional compound containing at least two functional groups capable of reacting with the amino group having 1 or 2 active hydrogen atoms; and a process for preparing the same. The semipermeable composite membrane of this invention is especially useful for desalination of saline or brackish water by reverse osmosis.
摘要翻译：一种半透性复合膜，其包含沉积在微孔基材的一侧上的聚合材料的薄的半透膜，所述聚合物材料通过交联含有至少30摩尔％的式（IMAGE）的重复单元的可溶性聚合物制备，其中所有符号如本文所定义，并且每克所述聚合物具有至少0.5毫当量的含有1或2个活性氢原子的氨基，和具有至少两个能够与具有1个氨基的氨基反应的官能团的多官能化合物或2个活性氢原子; 及其制备方法。本发明的半透膜复合膜特别适用于通过反渗透脱盐盐水或微咸水。

4. 发明授权

US4302336A Semipermeable composite membrane 失效
标题翻译：半透膜复合膜
公开(公告)号：US4302336A
公开(公告)日：1981-11-24
申请号：US72044
申请日：1979-09-04
申请人： Takeyuki Kawaguchi , Yutaka Taketani , Noriaki Sasaki , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara
发明人： Takeyuki Kawaguchi , Yutaka Taketani , Noriaki Sasaki , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara
IPC分类号： C08J9/28 , B01D69/12 , B01D71/40 , B01D71/44 , B01D71/60 , B01D71/82 , C08G85/00 , B01D3/00 , B01D13/00
CPC分类号： B01D71/60 , B01D69/125 , B01D71/44 , C08G85/004
摘要： A semipermeable composite membrane comprising a thin semipermeable film of a polymeric material deposited on one side of a microporous substrate, said polymeric material being prepared by crosslinking a soluble polymer containing at least 30 mole % of a recurring unit of the formula ##STR1## wherein all symbols are as defined in claim 1, and having at least 0.2 milliequivalent, per gram of said polymer, of an amino group containing 1 or 2 active hydrogen atoms, with a polyfunctional compound containing at least two functional groups capable of reacting with the amino group having 1 or 2 active hydrogen atoms; and a process for preparing the same. The semipermeable composite membrane of this invention is especially useful for desalination of saline or brackish water by reverse osmosis.
摘要翻译：一种半透膜复合膜，其包含沉积在微孔基材的一侧上的聚合物材料的薄的半透膜，所述聚合物材料通过交联含有至少30摩尔％的式“IMAGE”的重复单元的可溶性聚合物制备，其中所有符号如权利要求1中所定义，并且每克所述聚合物具有至少0.2毫当量的含有1或2个活性氢原子的氨基，和具有至少两个能够与氨基反应的官能团的多官能化合物具有1或2个活性氢原子; 及其制备方法。本发明的半透膜复合膜特别适用于通过反渗透脱盐盐水或微咸水。

5. 发明授权

US4242208A Semipermeable composite membrane and process for preparation thereof 失效
标题翻译：半透膜复合膜及其制备方法
公开(公告)号：US4242208A
公开(公告)日：1980-12-30
申请号：US39559
申请日：1979-05-16
申请人： Takeyuki Kawaguchi , Yutaka Taketani , Hiroyoshi Minematsu , Noriaki Sasaki , Yuzuru Hayashi , Shigeyoshi Hara
发明人： Takeyuki Kawaguchi , Yutaka Taketani , Hiroyoshi Minematsu , Noriaki Sasaki , Yuzuru Hayashi , Shigeyoshi Hara
IPC分类号： B01D71/82 , B01D69/12 , B01D71/62 , B01D71/66 , B01D39/00 , B01D13/00 , B05D5/00 , C08C19/22
CPC分类号： B01D71/66 , B01D69/125 , B01D71/62
摘要： A semipermeable composite membrane comprising a thin semipermeable film of a polymeric material deposited on one side of the microporous substrate, said polymeric material being prepared by interfacial crosslinking of a polymer containing a recurring unit of the formula ##STR1## wherein each of R.sub.1 and R.sub.2 represents a hydrogen atom or a methyl group, and W.sub.1 represents a direct bonding or a sulfonyl group (--SO.sub.2 --), with a polyfunctional compound containing at least two functional groups selected from acid halide, sulfonyl halide, isocyanate, N-haloformyl, haloformate and acid anhydride groups; and a process for producing the same. The semipermeable composite membrane of this invention is especially useful for desalination of saline or brackish water by reverse osmosis.
摘要翻译：一种半透膜复合膜，其包含沉积在微孔基材的一侧上的聚合材料的薄的半透膜，所述聚合物材料通过含有式（I）的重复单元的聚合物的界面交联制备，其中每个R 1 并且R 2表示氢原子或甲基，并且W 1表示直接键合或磺酰基（-SO 2 - ），其中多官能化合物含有至少两个选自酰卤，磺酰卤，异氰酸酯，N-卤代甲酰基，卤代甲酸酯和酸酐基团; 及其制造方法。本发明的半透膜复合膜特别适用于通过反渗透脱盐盐水或微咸水。

6. 发明授权

US4388189A Process for preparation of improved semipermeable composite membranes 失效
标题翻译：改良半透膜复合膜的制备方法
公开(公告)号：US4388189A
公开(公告)日：1983-06-14
申请号：US220081
申请日：1980-12-24
申请人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara
发明人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara
IPC分类号： B01D71/28 , B01D69/12 , B01D71/38 , B01D71/48 , B01D71/52 , B01D71/60 , B01D71/66 , B01D71/82 , B01D31/00
CPC分类号： B01D69/125 , B01D71/60
摘要： In a process for producing a semipermeable composite membrane which comprises forming on a microporous substrate a thin layer of a polymeric material comprising a polyamino polymer containing at least 1 milliequivalent, per gram of the polymer in the dry state, of active amino groups selected from primary amino groups and secondary amino groups, and thereafter interfacially crosslinking a surface portion of said thin layer with a crosslinking agent having at least two functional groups (a) capable of easily reacting with either the primary or secondary amino groups or both in said polymer; the improvement wherein(1) said polymeric material contains dispersed therein a polyfunctional compound having at least two functional groups (b) substantially incapable of reacting with the primary or secondary amino groups in said polymer at a temperature at which the interfacial crosslinking is carried out, but capable of reacting easily with either the primary or secondary amino groups or both in said polymer at a temperature at least 30.degree. C. higher than said crosslinking temperature, and(2) the interfacially crosslinked thin layer is heated to a temperature at which said polyfunctional compound reacts with the primary or secondary amino groups or both in said polymer.
摘要翻译：在一种制备半透膜复合膜的方法中，该方法包括在微孔基材上形成包含聚氨基聚合物的聚合物材料的薄层，所述聚合物材料含有至少1毫当量的每克干燥状态的聚合物，选自主要氨基和仲氨基，然后用具有至少两个能够容易地与所述聚合物中的伯或仲氨基反应的二官能团（a）的交联剂与所述薄层的表面部分进行界面交联; 改进之处在于（1）所述聚合材料含有分散有至少两个官能团的多官能化合物（b）在进行界面交联的温度下基本上不能与所述聚合物中的伯或仲氨基发生反应，但能够在高于所述交联温度的至少30℃的温度下容易地与所述聚合物中的伯或仲氨基或两者反应，和（2）将界面交联的薄层加热至所述多官能化合物与所述聚合物中的伯或仲氨基或两者反应。

7. 发明授权

US4360434A Amphoteric ion-permeable composite membrane 失效
标题翻译：两性离子渗透复合膜
公开(公告)号：US4360434A
公开(公告)日：1982-11-23
申请号：US225324
申请日：1981-01-15
申请人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara , Fumio Ueda
发明人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Yuzuru Hayashi , Shigeyoshi Hara , Fumio Ueda
IPC分类号： B01D67/00 , B01D69/12 , B01D71/60 , C08J5/22 , G01N27/40 , B05D3/10 , B05D5/00
CPC分类号： B01D67/0093 , B01D69/125 , B01D71/60 , G01N27/40 , B01D2323/30 , Y10T428/249978 , Y10T428/249981
摘要： An amphoteric ion-permeable composite membrane composed of a microporous substrate, and supported on the substrate, a thin amphoteric ion-exchange film formed of an active amino group-containing polymer which has been interfacially crosslinked at least at the surface portion of the thin film, said membrane being produced by forming a thin layer comprising an active amino group-containing polymer containing 1.0 to 23 milliequivalents/g, as amino equivalent, of an active amino group selected from primary and secondary amino groups and 0 to 18 milliequivalents/g, as amino equivalent, of a tertiary amino group and/or an ammonium salt group per molecule with the total amino content thereof being in the range of 2.0 to 23 milliequivalents/g on the microporous substrate and then contacting the thin layer on the substrate interfacially with a polyfunctional aromatic compound containing at least two functional groups selected from carbonyl halide groups, sulfonyl halide groups, carboxylic acid anhydride groups, sulfonic acid anhydride groups and derivative groups of carboxylic acids and sulfonic acids having equivalent reactivity to the aforesaid halide and anhydride groups.
摘要翻译：由微孔基材构成并负载在基板上的两性离子透过性复合膜由至少在薄膜的表面部分进行了界面交联的含活性氨基聚合物形成的薄的两性离子交换膜所述膜通过形成包含含有选自伯氨基和仲氨基的活性氨基和0至18毫当量/克的作为氨基当量的1.0至23毫当量/克的含有活性氨基的聚合物的薄层，作为氨基当量的每个分子的叔氨基和/或铵盐基团，其总氨基含量在微孔基材上在2.0至23毫当量/ g的范围内，然后使基底上的薄层与含有至少两个选自羰基卤基，磺酰卤基，羧酸的官能团的多官能芳族化合物酸酐基团，磺酸酐基团和与上述卤化物和酸酐基团具有等同反应性的羧酸和磺酸的衍生基团。

8. 发明授权

US4820649A Method and kit having layered device for detecting biological component by interference color 失效
标题翻译：具有用于通过干涉色检测生物成分的分层装置的方法和试剂盒
公开(公告)号：US4820649A
公开(公告)日：1989-04-11
申请号：US99906
申请日：1987-09-22
申请人： Takeyuki Kawaguchi , Takashi Shiro
发明人： Takeyuki Kawaguchi , Takashi Shiro
IPC分类号： G01N21/29 , G01N21/55 , G01N21/75 , G01N33/52 , G01N33/543 , G01N33/53 , G01N33/553
CPC分类号： G01N21/75 , G01N33/525 , G01N33/54366 , G01N21/29 , G01N21/55 , Y10S436/805 , Y10S436/808
摘要： A method for detecting a component of a biological system, which comprises contacting a biological component detecting device composed of a light reflecting substrate (I) substantially free from diffused reflection, a light interference layer (II) formed on the substrate (I), and a layer (III) of a substance for detecting said biological component provided at least in a region on the layer (II), with a solution presumed to contain the biological component to be detected, then forming a light-transmitting reflecting layer (IV) on its surface, and thereafter detecting the color of light interference or the brightness of the reflected light on the surface of the device.
摘要翻译：一种用于检测生物系统的部件的方法，包括使由基本上不含扩散反射的光反射基板（I）构成的生物成分检测装置，形成在基板（I）上的光干涉层（II）和用于检测至少在层（II）上的区域中提供的所述生物成分的物质层（III），其中假定含有要检测的生物成分的溶液，然后形成透光反射层（IV）在其表面上，然后检测装置的表面上的光干涉的颜色或反射光的亮度。

9. 发明授权

US5658466A Method of sterilizing a blood dialyzer having semipermeable polymeric membranes by .gamma.-ray irradiation 失效
标题翻译：通过γ射线照射对具有半透性聚合物膜的血液透析器进行灭菌的方法
公开(公告)号：US5658466A
公开(公告)日：1997-08-19
申请号：US404311
申请日：1995-03-15
申请人： Takeyuki Kawaguchi , Hironori Matsuda , Masaaki Tsukioka , Takahiro Daido
发明人： Takeyuki Kawaguchi , Hironori Matsuda , Masaaki Tsukioka , Takahiro Daido
IPC分类号： A61L2/08 , B01D65/02 , A61L2/00
CPC分类号： A61L2/08 , B01D65/022 , B01D2321/28 , B01D2321/346
摘要： A blood dialyzer having semipermeable polymeric dialyzing membranes is sterilized by impregnating the dialyzing membranes, for example, dialyzing hollow fibers, with an aqueous solution of a .gamma.-ray-absorbent and water-soluble dihydric aliphatic alcohol and irradiating .gamma.-rays to the dialyzing membranes, to prevent the deterioration of the dialyzing membranes and the generation of ultraviolet-ray-absorbent substance in the dialyzing membrane.
摘要翻译：具有半透性聚合物透析膜的血液透析器通过用γ-射线吸收剂和水溶性二羟基脂肪醇的水溶液浸渍透析膜，例如透析中空纤维来灭菌，并将γ射线照射到透析膜，以防止透析膜的劣化和透析膜中的紫外线吸收物质的产生。

10. 发明授权

US06433054B1 Gel-form pressure-sensitive adhesive, and adhesive material and adhesive medicinal preparation both containing the same 失效
标题翻译：凝胶型压敏粘合剂，以及含有相同材料的粘合剂和粘合剂制剂
公开(公告)号：US06433054B1
公开(公告)日：2002-08-13
申请号：US09508765
申请日：2000-03-16
申请人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Susumu Maruo , Hiroaki Kuwahara , Takanori Miyoshi , Michio Iwai
发明人： Takeyuki Kawaguchi , Hiroyoshi Minematsu , Susumu Maruo , Hiroaki Kuwahara , Takanori Miyoshi , Michio Iwai
IPC分类号： C08K509
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7069 , A61L15/58 , C08G2170/40 , C08L31/00 , C08L33/00 , C08L67/025 , C08L71/02 , C08L75/04 , C08L2666/04 , C08L2666/14 , C08L2666/28 , C09J131/04 , C09J133/08 , C09J167/00 , C09J167/025 , C09J175/04 , C09J177/00 , C08L67/00 , C08L77/00
摘要： The gel adhesive of the present invention contains an elastomer component (A), a self-adhesive polymer component (B) compatible with the elastomer component (A), and a liquid component (C) compatible with the elastomer component (A) and the self-adhesive polymer (B), the liquid component (C) being held in a mixture of the elastomer component (A) and the self-adhesive polymer (B) without exuding, to form as a whole, a gel, and is useful for forming a self-adhesive layer of an adhesive material or a pharmaceutical-containing self-adhesive layer of an adhering pharmaceutical preparation, which layer is capable of being firmly adhered to a surface to be adhered, and particularly a body skin surface, and of being easily removed therefrom without leaving a portion of the layer on the adhered surface.
摘要翻译：本发明的凝胶粘合剂含有弹性体成分（A），与弹性体成分（A）相容的自粘聚合物成分（B）和与弹性体成分（A）相容的液体成分（C）和自粘聚合物（B），液体组分（C）保持在弹性体组分（A）和自粘聚合物（B）的混合物中而不渗出，从而形成凝胶，并且是有用的用于形成粘合剂材料的自粘合层或粘附药物制剂的含药物的自粘合层，该层能够牢固地粘附到待粘附的表面，特别是身体表皮表面，以及容易地从中去除，而不会在粘合表面上留下一部分层。

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