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    • 8. 发明授权
    • Method of measuring quantity of substrate
    • 测量基材数量的方法
    • US08668820B2
    • 2014-03-11
    • US12802608
    • 2010-06-10
    • Shoji MiyazakiHiroyuki TokunagaYoshinobu Tokuno
    • Shoji MiyazakiHiroyuki TokunagaYoshinobu Tokuno
    • G01N27/327
    • G01N27/327A61B5/1486A61B2562/0295C12Q1/001C12Q1/005C12Q1/006G01N27/26G01N27/3272G01N27/3274G01N33/48771G01N33/5438
    • A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
    • 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极,插入到测量装置中,该测量装置包括用于可拆卸地支撑生物传感器的支撑部分,要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时,生物传感器的电极中的一个连接到测量装置的第一和第二连接端子,并且具有这样的结构,使得电极在第一和第二 由驱动电源施加电压引起的连接端子。
    • 9. 发明申请
    • BIOLOGICAL SAMPLE MEASURING DEVICE AND METHOD FOR MEASURING BIOLOGICAL SAMPLE USING SAME
    • 生物样品测量装置和使用其测量生物样品的方法
    • US20130337571A1
    • 2013-12-19
    • US14003090
    • 2012-05-10
    • Daiki MizuokaHiroyuki TokunagaTsuyoshi Takahashi
    • Daiki MizuokaHiroyuki TokunagaTsuyoshi Takahashi
    • G01N33/66
    • G01N33/66G01N27/3273G01N27/3274Y10T436/144444
    • With this biological sample measuring device, the determination section performs measurement at specific intervals in a first measurement period from the start of measurement until a first time, and performs measurement at specific intervals in a second measurement period that comes after the first measurement period, calculates the difference between the measurement values in corresponding specific periods, and finds a plurality of first difference determination values, on the basis of a plurality of current values measured in the first measurement period and a plurality of current values measured in the second measurement period, finds a second difference determination value by finding the difference at specific intervals in the plurality of first difference determination values, and determines whether or not a reagent movement error and/or exposure error of the biological sample measurement sensor has occurred, on the basis of the first and second difference determination values.
    • 在该生物样本测定装置中,决定部在从开始测量直到第一次的第一测量期间内以特定间隔进行测量,并且在第一测定周期之后的第二测定期间内,以规定间隔进行测定, 基于在第一测量周期中测量的多个电流值和在第二测量周期中测量的多个电流值,在相应的特定周期中的测量值之间的差异,并且找到多个第一差分确定值,找到 第二差分确定值,通过在多个第一差分确定值中以特定间隔找到差异,并且基于第一差异确定值确定生物样本测量传感器的试剂移动误差和/或曝光误差是否已经发生 和第二差分确定值。
    • 10. 发明授权
    • Biosensor
    • 生物传感器
    • US08475638B2
    • 2013-07-02
    • US12823676
    • 2010-06-25
    • Hiroyuki TokunagaShoji MiyazakiEriko Yamanishi
    • Hiroyuki TokunagaShoji MiyazakiEriko Yamanishi
    • G01N27/327
    • C12Q1/001G01N27/3272
    • In a biosensor that detects introduction of a sample liquid into a specimen supply path using a detecting electrode, a means of improving accuracy of detection is provided. The biosensor has: an electrode system including measuring electrode, counter electrode, and detecting electrode on first electrically insulating support; specimen supply path for introducing the sample liquid; and reagent layer used for quantifying a substrate contained in the sample liquid. The means is characterized in that detecting electrode is spaced from measuring electrode by a distance sufficient for the sample liquid to sufficiently cover measuring electrode before the sample liquid reaches detecting electrode.
    • 在使用检测电极检测样本液体进入样本供给路径的生物传感器中,提供提高检测精度的手段。 生物传感器具有:电极系统,其包括第一电绝缘支撑件上的测量电极,对电极和检测电极; 用于引入样品液的样品供应路径; 以及用于定量样品液体中所含的基板的试剂层。 该装置的特征在于,检测电极与测量电极隔开足够的距离,使得样品液体在样品液体到达检测电极之前足以覆盖测量电极。