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1. 发明授权

US4594868A System and plate bending machine for registering in an offset printing press 失效
标题翻译：系统和板材弯曲机，用于记录胶版印刷机
公开(公告)号：US4594868A
公开(公告)日：1986-06-17
申请号：US631200
申请日：1984-07-16
申请人： Hideo Takeuchi , Michiaki Kobayashi , Hiroyuki Hashimoto , Daiji Suzuki
发明人： Hideo Takeuchi , Michiaki Kobayashi , Hiroyuki Hashimoto , Daiji Suzuki
IPC分类号： B41F13/12 , B41F27/00 , B41F33/00 , G03F9/00 , B21D5/04
CPC分类号： B41F27/005 , B41F13/12 , B41F33/0081 , G03F9/00
摘要： A method for registering in an offset printing press comprises: mounting a printing plate on a shiftable table of a plate bending machine; detecting datum fine lines on said plate, by means of optical sensors; shifting the shiftable table so that said datum fine lines are placed at specific positions; inscribing, by means of a register mark inscribing device, register marks for carrying out automatic registering while, at the same time, bending the lateral edges of the printing plate; thereafter mounting the printing plate on a corresponding plate cylinder of a printing press; and carrying out automatic registering. The above plate bending machine comprises plate bending mechanisms, a shiftable table for holding the printing plate, optical detection sensors disposed above the shiftable table and operating to detect datum lines on the plate and thereby to generate signals for the movement of the table and register mark inscribing devices for automatic registering on a plate cylinder of the printing press.
摘要翻译：一种用于记录胶版印刷机的方法，包括：将印版安装在平板折弯机的可移动台上; 通过光学传感器检测所述板上的基准细线; 移动可移动台，使得所述基准细线被放置在特定位置; 通过对准标记刻印装置刻印用于进行自动登记的对准标记，同时弯曲印版的侧边缘; 然后将印版安装在印刷机的对应印版滚筒上; 并进行自动注册。上述板材弯曲机包括板弯曲机构，用于保持印版的可移动台，设置在可移动台上方的光学检测传感器，并操作以检测板上的基准线，从而产生用于移动台和对准标记的信号用于在印刷机的印版滚筒上自动记录的印刷装置。

2. 发明授权

US4582768A Method for forming register marks 失效
标题翻译：形成对准标记的方法
公开(公告)号：US4582768A
公开(公告)日：1986-04-15
申请号：US716822
申请日：1985-03-27
申请人： Hideo Takeuchi , Michiaki Kobayashi , Hiroyuki Hashimoto , Daiji Suzuki
发明人： Hideo Takeuchi , Michiaki Kobayashi , Hiroyuki Hashimoto , Daiji Suzuki
IPC分类号： B41F33/00 , B41F33/14 , G03F9/00 , B41M1/14 , G01B11/16 , G01N33/48
CPC分类号： G03F9/00 , Y10S101/36
摘要： A method for forming or marking register marks used for the automatic registration between a plurality of printing plates in a printing press. A register mark forming or marking device is mounted on a printing frame of an automatic composer so that a register mark can be formed or marked on a printing plate simultaneously with the printing of a film original over the printing plate. Misalignment between the thus formed or marked register marks and patterns or images can be eliminated.
摘要翻译：用于形成或标记用于印刷机中的多个印版之间的自动对准的对准标记的方法。对准标记形成或标记装置安装在自动作曲者的打印框架上，使得可以在印版上形成或标记对准标记，同时在印版上印刷胶片原稿。可以消除由此形成的或标记的对准标记和图案或图像之间的对准。

3. 发明授权

US4489652A Method, system, and plate bending machine for registering in an offset printing press 失效
标题翻译：方法，系统和板材弯曲机，用于记录胶版印刷机
公开(公告)号：US4489652A
公开(公告)日：1984-12-25
申请号：US434241
申请日：1982-10-14
申请人： Hideo Takeuchi , Michiaki Kobayashi , Hiroyuki Hashimoto , Daiji Suzuki
发明人： Hideo Takeuchi , Michiaki Kobayashi , Hiroyuki Hashimoto , Daiji Suzuki
IPC分类号： B41F27/00 , B41F13/12 , B41F29/00
CPC分类号： B41F27/005 , Y10S101/36
摘要： A method for registering in an offset printing press comprises: mounting a printing plate on a shiftable table of a plate bending machine; detecting datum fine lines on said plate, by means of optical sensors; shifting the shiftable table so that said datum fine lines are placed at specific positions; inscribing, by means of a register mark inscribing device, register marks for carrying out automatic registering while, at the same time, bending the lateral edges of the printing plate; thereafter mounting the printing plate on a corresponding plate cylinder of a printing press; and carrying out automatic registering. The above plate bending machine comprises plate bending mechanisms, a shiftable table for holding the printing plate, optical detection sensors disposed above the shiftable table and operating to detect datum lines on the plate and thereby to generate signals for the movement of the table and register mark inscribing devices for automatic registering on a plate cylinder of the printing press.
摘要翻译：一种用于记录胶版印刷机的方法，包括：将印版安装在平板折弯机的可移动台上; 通过光学传感器检测所述板上的基准细线; 移动可移动台，使得所述基准细线被放置在特定位置; 通过对准标记刻印装置刻印用于进行自动登记的对准标记，同时弯曲印版的侧边缘; 然后将印版安装在印刷机的对应印版滚筒上; 并进行自动注册。上述板材弯曲机包括板弯曲机构，用于保持印版的可移动台，设置在可移动台上方的光学检测传感器，并操作以检测板上的基准线，从而产生用于移动台和对准标记的信号用于在印刷机的印版滚筒上自动记录的印刷装置。

4. 发明授权

US09448241B2 Mass spectrometry method for a polypeptide including a cysteine residue 有权
标题翻译：包含半胱氨酸残基的多肽的质谱法
公开(公告)号：US09448241B2
公开(公告)日：2016-09-20
申请号：US13576124
申请日：2011-03-28
申请人： Jumpei Naito , Shuya Satoh , Manabu Komatsu , Hiroyuki Hashimoto
发明人： Jumpei Naito , Shuya Satoh , Manabu Komatsu , Hiroyuki Hashimoto
IPC分类号： G01N33/68 , H01J49/00
CPC分类号： G01N33/6851 , H01J49/00 , Y10T436/182
摘要： The problem to be solved by the present invention is to provide a method for treating a polypeptide including a cysteine residue for enhancing the sensitivity of detection thereof in mass spectrometry using charged particles. A mass spectrometry method for a polypeptide including a cysteine residue is provided which includes treating the polypeptide including a cysteine residue with a cyanation agent, treating the cyanated polypeptide with a base, and then desorption ionizing the base-treated polypeptides using charged particles for mass spectrometry.
摘要翻译：本发明要解决的问题是提供一种用于在使用带电粒子的质谱法中治疗包含半胱氨酸残基的多肽以提高其检测灵敏度的方法。提供了包括半胱氨酸残基的多肽的质谱法，其包括用氰化剂处理包含半胱氨酸残基的多肽，用碱处理氰化多肽，然后使用带电粒子对基质处理的多肽进行解吸，用于质谱法。

5. 发明授权

US08754363B2 Method and apparatus for reducing noise in mass signal 有权
标题翻译：用于降低质量信号噪声的方法和装置
公开(公告)号：US08754363B2
公开(公告)日：2014-06-17
申请号：US13575600
申请日：2011-01-31
申请人： Koichi Tanji , Manabu Komatsu , Hiroyuki Hashimoto
发明人： Koichi Tanji , Manabu Komatsu , Hiroyuki Hashimoto
IPC分类号： H01J49/26 , G06F17/14 , H01J49/00
CPC分类号： H01J49/0036 , H01J49/0004
摘要： A more effective noise reduction method is provided. In the method, when mass spectrum information having a spatial distribution is processed, the whole data is taken as three-dimensional data (positional information is stored in an xy plane, and spectral information is stored along a z-axis direction), and three-dimensional wavelet noise reduction is performed by applying preferable basis functions to a spectral direction and a peak distribution direction (in-plane direction).
摘要翻译：提供了更有效的降噪方法。在该方法中，当处理具有空间分布的质谱信息时，将整个数据作为三维数据（位置信息存储在xy平面中，并且光谱信息沿z轴方向存储），并且三个通过对光谱方向和峰分布方向（面内方向）应用优选的基函数来进行维小波噪声降低。

6. 发明授权

US08704194B2 Information acquiring apparatus and information acquiring method for acquiring mass-related information 失效
标题翻译：信息获取装置和用于获取大量相关信息的信息获取方法
公开(公告)号：US08704194B2
公开(公告)日：2014-04-22
申请号：US13083510
申请日：2011-04-08
申请人： Manabu Komatsu , Hiroyuki Hashimoto
发明人： Manabu Komatsu , Hiroyuki Hashimoto
IPC分类号： H01J49/14 , H01J49/10
CPC分类号： H01J49/06 , H01J49/0463
摘要： Target molecules in a sample can be detected at an improved sensitivity by means of a mass spectrometer. A sample with or without a matrix is placed on a substrate and irradiated with a converged and pulsed primary beam selected from an ion beam, a neutral particle beam or a laser beam. Secondary ions and neutral molecules are emitted along with protons from the irradiated point of the sample as an electric field is applied between the substrate and an extraction electrode disposed above the substrate. A proton-control electrode is arranged in axial symmetry with the trajectory of the primary beam. A voltage is applied thereto so that the generated electric field decelerates the flying protons to raise their adhering efficiency to the flying neutral molecules.
摘要翻译：可以通过质谱仪以更高的灵敏度检测样品中的靶分子。将具有或不具有矩阵的样品放置在基底上并用从离子束，中性粒子束或激光束中选择的会聚且脉冲的一次束照射。随着电场施加在基板和设置在基板之上的引出电极之间，二次离子和中性分子与质子的辐射点一起被发射出来。质子控制电极与主光束的轨迹轴对称。施加电压使得所产生的电场使飞行质子减速，以提高它们对飞行中性分子的附着效率。

7. 发明授权

US08702415B2 Apparatus for feeding molten resin 有权
标题翻译：用于进料熔融树脂的设备
公开(公告)号：US08702415B2
公开(公告)日：2014-04-22
申请号：US12670414
申请日：2008-09-03
申请人： Hideto Monzen , Hiroyuki Hashimoto , Takuya Fujikawa , Hiroshi Hayashi , Tsuneo Imatani
发明人： Hideto Monzen , Hiroyuki Hashimoto , Takuya Fujikawa , Hiroshi Hayashi , Tsuneo Imatani
IPC分类号： B29C43/34
CPC分类号： B29C43/34 , B29B11/12 , B29B11/14 , B29B2911/1402 , B29B2911/14026 , B29B2911/14033 , B29B2911/1404 , B29B2911/14106 , B29B2911/14213 , B29B2911/14326 , B29B2911/14333 , B29B2911/1444 , B29B2911/14466 , B29C31/048 , B29C43/08 , B29C47/0016 , B29C47/003 , B29C47/0042 , B29C2043/3466 , B29C2043/3676 , B29C2793/009 , B29K2067/00 , B29K2105/04 , B29K2105/258
摘要： The invention also provides for an apparatus for feeding molten resin, wherein the apparatus includes holding units each having a respective holding portion that is opened and closed to hold a molten resin that is discharged from an extrusion port of a die head of an extruder and is cut by a cutter while moving on a track, in which, after the respective holding portion transfers the molten resin from the extrusion port to a female mold, a side of the respective holding portion is opened and the molten resin is fed down to the female mold in a compression-molding machine, wherein a plurality of longitudinal grooves extending up and down are formed in an inner circumferential surface of the respective holding portion that holds the molten resin.
摘要翻译：本发明还提供一种用于进料熔融树脂的设备，其中该设备包括保持单元，每个保持单元具有打开和关闭的相应的保持部分，以保持从挤出机的模头的挤出口排出的熔融树脂，并且是在轨道上移动时由切割器切割，其中在各个保持部分将熔融树脂从挤出口转移到阴模之后，各个保持部分的一侧被打开，并且熔融树脂被向下馈送到母体在压缩成型机中模具，其中在保持熔融树脂的各个保持部分的内周表面中形成有上下延伸的多个纵向槽。

8. 发明授权

US08415615B2 Information acquisition method 失效
标题翻译：信息采集方法
公开(公告)号：US08415615B2
公开(公告)日：2013-04-09
申请号：US13351675
申请日：2012-01-17
申请人： Shuya Satoh , Hiroyuki Hashimoto
发明人： Shuya Satoh , Hiroyuki Hashimoto
IPC分类号： H01J49/26
CPC分类号： H01J49/142 , Y10T436/24 , Y10T436/25 , Y10T436/25875
摘要： Provided is a method that achieves both of soft ionization and high ionization efficiency of a substance to be analyzed at each measurement site without impairing a two-dimensional distribution state of the substance to be analyzed in desorption ionization mass spectrometry of a substance to be measured. By applying, to a substance to be analyzed, an ionization assisting reagent including an organic acid including a functional group represented by —(CF2)COOH and having a boiling point of 150° C. or more, and a polyhydric alcohol having a melting point of 20° C. or less and a boiling point of 150° C. or more at normal pressure, the organic acid, which is a component of the ionization assisting reagent, effectively donates a proton to the substance to be analyzed, thereby improving ionization efficiency, and the polyhydric alcohol, which is a component of the ionization assisting reagent, inhibits fragmentation.
摘要翻译：本发明提供了一种能够在每个测量部位实现待分析物质的软电离和高电离效率的方法，而不会在待测物质的解吸电离质谱中损害待分析物质的二维分布状态。通过将被分析物质应用于包含由 - （CF 2）COOH表示的官能团和沸点为150℃以上的有机酸的电离助剂和具有150℃以上的沸点的多元醇在常压下为20℃以下，沸点为150℃以上，作为电离辅助剂的成分的有机酸能够有效地向待分析物质提供质子，从而提高离子化作为电离助剂的成分的多元醇抑制分解。

9. 发明申请

US20110146202A1 METAL MOLD FOR COMPRESSION-MOLDING PREFORM, PREFORM, SYSTEM FOR ASEPTICALLY FILLING BEVERAGES AND FOODS USING THE SAME AND METHOD OF PRODUCING BLOW-MOLDED CONTAINERS 有权
标题翻译：用于压缩成型预制件的金属模具，用于自助填充饮料的系统和使用其的食品和生产吹塑容器的方法
公开(公告)号：US20110146202A1
公开(公告)日：2011-06-23
申请号：US13059750
申请日：2009-08-19
申请人： Tsuneo Imatani , Takeshi Iwashita , Hiroyuki Hashimoto , Hideto Monzen , Hotaka Fukabori , Hiroyuki Kondou
发明人： Tsuneo Imatani , Takeshi Iwashita , Hiroyuki Hashimoto , Hideto Monzen , Hotaka Fukabori , Hiroyuki Kondou
IPC分类号： B65B55/02 , B32B1/02 , B29C49/02
CPC分类号： B65B3/022 , B29B11/12 , B29B11/14 , B29B2911/1402 , B29B2911/14026 , B29B2911/14033 , B29B2911/1404 , B29B2911/14106 , B29B2911/14213 , B29B2911/14326 , B29B2911/14333 , B29B2911/14413 , B29B2911/1444 , B29B2911/14466 , B29C43/08 , B29C43/34 , B29C43/42 , B29C49/02 , B29C49/64 , B29C2049/028 , B29D22/003 , B29K2067/00 , B29K2067/046 , B29K2105/258 , B29L2001/00 , B65B55/027 , B67B3/003 , B67C7/00 , B67C2003/227 , Y10T428/1397
摘要： [Problem] To realize a predetermined “aseptic level of the containers” without introducing a container sterilizing machine and to reduce the burden for adjusting the temperature of the preform.[Means for Solution] A metal mold for molding, wherein a space width (t2) of at least the body portion in the space width for forming a thickness of from the body portion to the bottom portion of the preform is set to lie in a range of 1.18 to 2.11 times as great as a space width (t1) for forming a thickness of an upper end portion of the mouth portion of the preform. At the time of the compression molding, the preform is taken out in the state of a high temperature from a compression-molding machine 31 and is fed to a bottle-producing unit C while maintaining the state of a high temperature. Further, the inner surfaces of a clean box I in which the units are placed and the outer surfaces of the units are sterilized, and the interior of the clean box I maintains a positive-pressure state with the filtered clean air. The bottle-producing unit C and a filling/sealing unit D are neighboring and directly coupled to each other in the same clean box, and are partitioned by a WBZ 54.
摘要翻译： [问题]在不引入容器消毒机的情况下实现预定的“无菌水平的容器”，并且减少调节预成型件的温度的负担。 [解决方案]一种用于模制的金属模具，其中，用于形成从预制件的主体部分到底部的厚度的空间宽度中的至少主体部分的空间宽度（t2）设置在为形成预成型体的口部的上端部的厚度的空间宽度（t1）的1.18〜2.11倍的范围。在压缩成型时，预成型体在高温状态下从压缩成型机31取出，并在保持高温状态的同时供给到制瓶单元C. 此外，其中放置单元的清洁箱I的内表面和单元的外表面被灭菌，并且清洁箱I的内部与被过滤的清洁空气保持正压状态。制瓶单元C和填充/密封单元D相邻并且在相同的清洁盒中彼此直接耦合，并且被WBZ 54分隔开。

10. 发明授权

US07851749B2 Method for obtaining information and device therefor 有权
标题翻译：获取信息的方法及其设备
公开(公告)号：US07851749B2
公开(公告)日：2010-12-14
申请号：US12017584
申请日：2008-01-22
申请人： Manabu Komatsu , Hiroyuki Hashimoto , Yohei Murayama , Kazuhiro Ban
发明人： Manabu Komatsu , Hiroyuki Hashimoto , Yohei Murayama , Kazuhiro Ban
IPC分类号： H01J49/00
CPC分类号： H01J49/142
摘要： A method for obtaining information on a mass of an object by time-of-flight mass spectrometry. This method includes placing colloidal metal particles for promoting ionization of the object inside the object at a depth ranging from 0.1 nm to 100 nm in opposition to a primary beam for the ionization; irradiating the object with the primary beam selected from the group of ions, neutral particles, and electrons, which can be focused, pulsed, and are capable of scanning, and laser beams, which can be focused, pulsed, and are capable of scanning to ionize a constituent of the object and to allow the ionized constituent to fly out of the object; and obtaining information on the mass of the flying constituent of the object by time-of-flight mass spectrometry.
摘要翻译：一种通过飞行时间质谱法获得物体质量信息的方法。该方法包括将胶体金属颗粒放置在与离子化的主光束相反的0.1nm至100nm范围内的物体内部物体的离子化; 用可以被聚焦，脉冲和能够扫描的离子，中性粒子和电子组中选择的主要束照射物体，以及可以被聚焦，脉冲且能够扫描的激光束电离物体的成分并使离子化成分从物体飞出; 并通过飞行时间质谱法获得关于物体飞行成分质量的信息。

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