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1. 发明申请

US20080232659A1 Analysis Processing Method and Device 审中-公开
标题翻译：分析处理方法和设备
公开(公告)号：US20080232659A1
公开(公告)日：2008-09-25
申请号：US11883439
申请日：2006-01-31
申请人： Hideji Tajima , Hideo Ikeda , Osamu Segawa
发明人： Hideji Tajima , Hideo Ikeda , Osamu Segawa
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06K2209/07
摘要： The invention relates to image processing, and to a method and device for recognizing the reaction results of a test sample in which various reagents are arranged on a surface, by image analysis, and assay. An object is to provide an analysis processing method and an analysis processing device which can obtain analysis results efficiently and with high accuracy, for objects which are integrated using a wound body which is wound with a linear base substance, and for which positions are uncertain. An analysis processing method for performing analysis based on optical information from a wound object which is wound with a linear base substance in which biological substances of previously determined types are immobilized, and a plurality of these immobilized spots are arranged at previously determined positions, includes: detecting a partial region belonging to the spots, by means of optical information obtained by scanning a surface of the wound body; specifying the spots belonging thereto, based on the detected partial region for the detected spots; and performing analysis of the spots based on the optical information from the specified spots.
摘要翻译：本发明涉及图像处理，以及用于识别其中各种试剂被布置在表面上的测试样品的反应结果的方法和装置，通过图像分析和测定。本发明的目的是提供一种分析处理方法和分析处理装置，该分析处理方法和分析处理装置可以有效地且高精度地获得分析结果，对于使用缠绕有线性基体的卷绕体并且其位置不确定而集成的对象。一种分析处理方法，用于根据来自被固定有先前确定类型的生物物质的线性基质物质的伤口物体的光学信息和多个这些固定化斑点进行分析，所述分析处理方法包括：通过扫描卷绕体的表面获得的光学信息来检测属于斑点的部分区域; 基于检测到的所检测到的部分区域指定属于其的点; 并且基于来自指定点的光学信息来执行点的分析。

2. 发明授权

US08506904B2 Sample arraying/assembling device, its method, and apparatus using sample assembly 失效
标题翻译：样品排列/组装装置，其方法和使用样品组件的装置
公开(公告)号：US08506904B2
公开(公告)日：2013-08-13
申请号：US13252879
申请日：2011-10-04
申请人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
发明人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
IPC分类号： B01L3/00 , B01L99/00 , C12M1/34 , C12M3/00
CPC分类号： B01L3/0241 , B01J2219/0081 , B01L3/5025 , B01L2300/0829 , B01L2300/0845 , B01L2400/0409
摘要： The present invention relates to a sample arraying/assembling device, its method, and an apparatus using a sample assembly, and has an object of providing a sample arraying/assembling device which is adapted to various microplates, and is capable of efficiently and quickly arraying and assembling various samples; its method; and an apparatus using a sample assembly.The present invention includes: a distributing section which is capable of holding respective solutions containing samples to be distributed, and which has a plurality of holding ends arranged in a predetermined matrix; and a wound body which has a plane surface wound with a slender foundation member on which samples are to be distributed at distribution intervals of column or line of the matrix, which is arranged in parallel at the winding intervals of the line or column on the plane surface, so that the respective holding ends can come into contact therewith.
摘要翻译：本发明涉及样品排列/组装装置，其方法和使用样品组件的装置，其目的是提供一种适用于各种微孔板的样品排列/组装装置，并且能够高效且快速地排列并组装各种样品; 其方法; 以及使用样品组件的装置。本发明包括：分配部分，其能够保持包含要分布的样品的各溶液，并且具有以预定矩阵排列的多个保持端; 以及卷绕体，其具有卷绕有细长基础构件的平面，所述基部构件将以矩阵的列或线的分布间隔分布样本，所述分隔间隔以平行于所述线或列的绕组间隔平行布置表面，使得各个保持端可以与其接触。

3. 发明授权

US08413489B2 Column tip processing device and column tip processing method 有权
标题翻译：柱尖处理装置和柱尖处理方法
公开(公告)号：US08413489B2
公开(公告)日：2013-04-09
申请号：US12665430
申请日：2008-06-18
申请人： Hideji Tajima , Osamu Segawa , Masanari Tsujimura
发明人： Hideji Tajima , Osamu Segawa , Masanari Tsujimura
IPC分类号： G01N30/84
CPC分类号： G01N35/10 , G01N1/405 , G01N30/6043 , G01N30/6091 , G01N2035/1053
摘要： The present invention relates to a column tip processing device and a column tip processing method, and its objective is to enhance the contact between a packing and a fluid as a subject to be processed whereby accomplishing a highly efficient reaction as well as an accurate processing, which has a nozzle head having a single or multiple-channeled nozzle, a suction and discharge mechanism, one or more types of column tips in which a packing is enclosed, a stage provided with a fluid housing part group including a plurality of fluid housing parts in which various solutions are or can be housed, and moving means for moving the nozzle head relatively to the fluid housing part group, and also has a controlling part which controls the suction and discharge mechanism and the moving means with regard to quantities, pressure, flow rate, the number of cycles, time or position of the suction or discharge by the nozzle based on a structural requirement relating to the structure of the one or more types of column tips to be fitted to the nozzle and a processing requirement relating to the processing contents involving one or more types of subject fluids subjected to the suction or discharge of the column tips.
摘要翻译：本发明涉及柱尖处理装置和柱尖处理方法，其目的是增强填料和作为待处理对象的流体之间的接触，从而实现高效反应以及精确的处理，其具有具有单通道或多通道喷嘴的喷嘴头，抽吸和排出机构，其中封装有填料的一种或多种类型的塔尖，设置有包括多个流体容纳部分的流体容纳部分组其中各种解决方案是或可以容纳的，以及用于相对于流体容纳部分组移动喷嘴头的移动装置，并且还具有控制部分，其控制吸入和排出机构以及移动装置的数量，压力，基于与一个或多个结构相关的结构要求，喷嘴的吸入或排出的流量，循环次数，时间或位置要安装到喷嘴的柱头类型以及涉及处理内容的处理要求涉及一种或多种类型的受到吸收或排出柱头的主体流体。

4. 发明申请

US20090298160A1 Reaction vessel and reaction controller 失效
标题翻译：反应容器和反应控制器
公开(公告)号：US20090298160A1
公开(公告)日：2009-12-03
申请号：US11664980
申请日：2005-10-05
申请人： Hideji Tajima , Yoshinao Hirahara , Osamu Segawa
发明人： Hideji Tajima , Yoshinao Hirahara , Osamu Segawa
IPC分类号： C12M1/00
CPC分类号： G01N21/0332 , B01L3/0275 , B01L3/502 , B01L3/5021 , B01L3/50851 , B01L2200/147 , B01L2300/0654 , B01L2300/0829 , B01L2300/0877 , B01L2300/1805 , B01L2400/0409 , B01L2400/0478 , G01N21/6428 , G01N21/6452 , G01N35/0099 , G01N2035/00376 , G01N2035/00524
摘要： The invention relates to a reaction vessel and a reaction controller, wherein temperature control of a liquid stored within the vessel can be performed with a high accuracy and faithful responsiveness. The reaction container and the reaction controller comprise one or a plurality of reaction chambers in which liquid is storable, and a wall that surrounds the reaction chamber, and the entirety or a part of the wall is formed by a temperature raising and lowering body that can raise or lower the temperature thereof according to a signal from an instructing part provided outside.
摘要翻译：本发明涉及一种反应容器和反应控制器，其中可以以高精度和忠实的响应性进行存储在容器内的液体的温度控制。反应容器和反应控制器包括一个或多个反应室，液体可存储在其中，并且包围反应室的壁，壁的整体或一部分由升温和降温体形成，根据来自外部指示部的信号升高或降低其温度。

5. 发明申请

US20070178580A1 Sample arraying/assembling device, its method, and apparatus using sample assembly 失效
标题翻译：样品排列/组装装置，其方法和使用样品组件的装置
公开(公告)号：US20070178580A1
公开(公告)日：2007-08-02
申请号：US10561550
申请日：2004-06-21
申请人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
发明人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
IPC分类号： C12M3/00
CPC分类号： B01L3/0241 , B01J2219/0081 , B01L3/5025 , B01L2300/0829 , B01L2300/0845 , B01L2400/0409
摘要： The present invention relates to a sample arraying/assembling device, its method, and an apparatus using a sample assembly, and has an object of providing a sample arraying/assembling device which is adapted to various microplates of International Standards, and is capable of efficiently and quickly arraying and assembling various samples; its method; and an apparatus using a sample assembly. The present invention is constituted to comprise: a distributing section which is capable of holding respective solutions containing samples to be distributed, and which has a plurality of holding ends arranged in a predetermined matrix; and a wound body which has a plane surface wound with a string-like or thread-like slender foundation member on which samples are to be distributed at distribution intervals of column or line of the matrix, which is arranged in parallel at the winding intervals of the line or column on the plane surface, so that the respective holding ends can come into contact therewith.
摘要翻译：本发明涉及一种样品排列/组装装置，其方法和使用样品组件的装置，其目的是提供一种适用于国际标准的各种微孔板的样品排列/组装装置，并且能够有效地并快速排列和组装各种样品; 其方法; 以及使用样品组件的装置。本发明构成为包括：分配部，其能够保持包含要分配的样品的各溶液，并且具有以预定矩阵排列的多个保持端; 以及卷绕体，其具有卷绕有弦状或螺纹状的细长基础构件的平面，所述基部构件将以矩阵的列或线的分布间隔分布样本，所述分隔间隔以在平面上的线或柱，使得相应的保持端可以与其接触。

6. 发明授权

US08445265B2 Reaction vessel and reaction controller 失效
公开(公告)号：US08445265B2
公开(公告)日：2013-05-21
申请号：US11664980
申请日：2005-10-05
申请人： Hideji Tajima , Yoshinao Hirahara , Osamu Segawa
发明人： Hideji Tajima , Yoshinao Hirahara , Osamu Segawa
IPC分类号： C12M1/34 , G01N21/00
CPC分类号： G01N21/0332 , B01L3/0275 , B01L3/502 , B01L3/5021 , B01L3/50851 , B01L2200/147 , B01L2300/0654 , B01L2300/0829 , B01L2300/0877 , B01L2300/1805 , B01L2400/0409 , B01L2400/0478 , G01N21/6428 , G01N21/6452 , G01N35/0099 , G01N2035/00376 , G01N2035/00524
摘要： The invention relates to a reaction vessel and a reaction controller, wherein temperature control of a liquid stored within the vessel can be performed with a high accuracy and faithful responsiveness. The reaction container and the reaction controller comprise one or a plurality of reaction chambers in which liquid is storable, and a wall that surrounds the reaction chamber, and the entirety or a part of the wall is formed by a temperature raising and lowering body that can raise or lower the temperature thereof according to a signal from an instructing part provided outside.

7. 发明申请

US20130084606A1 Composition for Preventing Evaporation of Reaction Solution During Nucleic Acid Amplification Reaction 审中-公开
标题翻译：用于防止核酸扩增反应期间反应溶液蒸发的组合物
公开(公告)号：US20130084606A1
公开(公告)日：2013-04-04
申请号：US13703603
申请日：2011-06-22
申请人： Takaki Sugimoto , Tetsuya Ueda , Osamu Segawa , Michinori Koizuka , Hideji Tajima
发明人： Takaki Sugimoto , Tetsuya Ueda , Osamu Segawa , Michinori Koizuka , Hideji Tajima
IPC分类号： C08L91/06 , C12Q1/68 , C12P19/34
CPC分类号： C08L91/06 , B01L3/0275 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L2200/0673 , B01L2200/142 , C08L91/00 , C08L2205/02 , C12P19/34 , C12Q1/6846 , C12Q1/6848 , C12Q2547/107 , Y02P20/149
摘要： The present invention provides a composition capable of hermetically sealing a PCR reaction vessel without using a closure member or adhesive seal. Disclosed is a composition for preventing evaporation of a nucleic acid amplification reaction solution during nucleic acid amplification reaction, which is a liquid during the reaction and becomes a solid through chemical or thermal changes after completion of the reaction. Also disclosed is a composition for preventing evaporation of a nucleic acid amplification reaction solution during nucleic acid amplification reaction, wherein the melting point of the composition is 0-15° C. Also disclosed is a composition for preventing evaporation of a nucleic acid amplification reaction solution during nucleic acid amplification reaction, wherein the melting point of the composition is 5-10° C.
摘要翻译：本发明提供能够不使用封闭构件或粘合剂密封而密封PCR反应容器的组合物。公开了用于在核酸扩增反应期间防止核酸扩增反应溶液蒸发的组合物，其在反应期间为液体，并且在反应完成后通过化学或热变化而变为固体。还公开了用于在核酸扩增反应期间防止核酸扩增反应溶液蒸发的组合物，其中组合物的熔点为0-15℃。还公开了一种用于防止核酸扩增反应溶液蒸发的组合物在核酸扩增反应期间，其中组合物的熔点为5-10℃

8. 发明申请

US20120053090A1 SAMPLE ARRAYING/ASSEMBLING DEVICE, ITS METHOD, AND APPARATUS USING SAMPLE ASSEMBLY 失效
标题翻译：样品阵列/装配装置，方法和使用样品装配的装置
公开(公告)号：US20120053090A1
公开(公告)日：2012-03-01
申请号：US13252879
申请日：2011-10-04
申请人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
发明人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
IPC分类号： C40B50/14 , C40B60/14 , C40B60/00
CPC分类号： B01L3/0241 , B01J2219/0081 , B01L3/5025 , B01L2300/0829 , B01L2300/0845 , B01L2400/0409
摘要： The present invention relates to a sample arraying/assembling device, its method, and an apparatus using a sample assembly, and has an object of providing a sample arraying/assembling device which is adapted to various microplates, and is capable of efficiently and quickly arraying and assembling various samples; its method; and an apparatus using a sample assembly.The present invention includes: a distributing section which is capable of holding respective solutions containing samples to be distributed, and which has a plurality of holding ends arranged in a predetermined matrix; and a wound body which has a plane surface wound with a slender foundation member on which samples are to be distributed at distribution intervals of column or line of the matrix, which is arranged in parallel at the winding intervals of the line or column on the plane surface, so that the respective holding ends can come into contact therewith.
摘要翻译：本发明涉及样品排列/组装装置，其方法和使用样品组件的装置，其目的是提供一种适用于各种微孔板的样品排列/组装装置，并且能够高效且快速地排列并组装各种样品; 其方法; 以及使用样品组件的装置。本发明包括：分配部分，其能够保持包含要分布的样品的各溶液，并且具有以预定矩阵排列的多个保持端; 以及卷绕体，其具有卷绕有细长基础构件的平面，所述基部构件将以矩阵的列或线的分布间隔分布样本，所述分隔间隔以平行于所述线或列的绕组间隔平行布置表面，使得各个保持端可以与其接触。

9. 发明授权

US08034303B2 Sample arraying/assembling device, its method, and apparatus using sample assembly 失效
标题翻译：样品排列/组装装置，其方法和使用样品组件的装置
公开(公告)号：US08034303B2
公开(公告)日：2011-10-11
申请号：US10561550
申请日：2004-06-21
申请人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
发明人： Hideji Tajima , Yukiko Miyashita , Osamu Segawa
IPC分类号： B01L3/00 , B01L99/00 , C12M1/34 , C12M3/00
CPC分类号： B01L3/0241 , B01J2219/0081 , B01L3/5025 , B01L2300/0829 , B01L2300/0845 , B01L2400/0409
摘要： The present invention relates to a sample arraying/assembling device, its method, and an apparatus using a sample assembly, and has an object of providing a sample arraying/assembling device which is adapted to various microplates of International Standards, and is capable of efficiently and quickly arraying and assembling various samples; its method; and an apparatus using a sample assembly.The present invention is constituted to comprise: a distributing section which is capable of holding respective solutions containing samples to be distributed, and which has a plurality of holding ends arranged in a predetermined matrix; and a wound body which has a plane surface wound with a string-like or thread-like slender foundation member on which samples are to be distributed at distribution intervals of column or line of the matrix, which is arranged in parallel at the winding intervals of the line or column on the plane surface, so that the respective holding ends can come into contact therewith.
摘要翻译：本发明涉及一种样品排列/组装装置，其方法和使用样品组件的装置，其目的是提供一种适用于国际标准的各种微孔板的样品排列/组装装置，并且能够有效地并快速排列和组装各种样品; 其方法; 以及使用样品组件的装置。本发明构成为包括：分配部，其能够保持包含要分配的样品的各溶液，并且具有以预定矩阵排列的多个保持端; 以及卷绕体，其具有卷绕有弦状或螺纹状的细长基础构件的平面，所述基部构件将以矩阵的列或线的分布间隔分布样本，所述分隔间隔以在平面上的线或柱，使得相应的保持端可以与其接触。

10. 发明授权

US5056427A Sealing of cavity on reagent tray 失效
标题翻译：在试剂盒上密封
公开(公告)号：US5056427A
公开(公告)日：1991-10-15
申请号：US493520
申请日：1990-03-14
申请人： Munechika Sakabe , Osamu Segawa
发明人： Munechika Sakabe , Osamu Segawa
IPC分类号： B01J19/16 , B01L3/00 , B01L7/00
CPC分类号： B01L3/50851 , B01J19/16 , B01L3/50853 , B01L7/00
摘要： A thermal reaction apparatus for sealing liquid within cavities includes a tray having cavities for storing therein liquid. The cavities have openings arranged at varying levels in thickness direction of the tray. A planar sealing member is disposed on the tray to cover the openings and is comprised of a pair of flexible sheets and viscous fluid filled between the flexible sheets. A pressure plate is disposed on the planar sealing member for applying thereto pressure effective to locally flow the viscous fluid to enable the sealing member to seal the varying levels of the cavity openings to thereby prevent evaporation of the liquid stored in the cavities. Alternatively, the elastic sealing member is comprised of an elastic sheet and projections arranged in registration with the respective cavities, and the pressure plate is disposed in contact with the projections for applying there to pressure effective to deform locally the sealing member through the projections to enable the sealing member to fittably seal the cavity openings. Or, the pressure plate may have projections, instead of the sealing member, in contact with the planar sealing member in registration to the respective cavities.

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