专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2003313200A Evaluation system for active peptide and new active peptide 有权
标题翻译：活性肽和新活性肽的评估系统
公开(公告)号：JP2003313200A
公开(公告)日：2003-11-06
申请号：JP2003042731
申请日：2003-02-20
申请人： Hidechika Okada , Okada Yuubu , 岡田有武 , 秀親岡田
发明人： OKADA HIDECHIKA , WILLIAM CAMPBELL , LAJOS BARANNI , OKADA NORIKO , LAWRENCE KLEIMAN
IPC分类号： C07K14/00 , C07K7/08
摘要： PROBLEM TO BE SOLVED: To provide a new active peptide exerting control action on a target peptide by effectively designing a peptide having reactivity to the target peptide and synthesizing the designed peptide.
SOLUTION: The evaluation system for peptide comprises a calculation means, wherein a hydrophobicity mean value is calculated from front and rear five or few amino acids of the peptide at each position except terminal amino acids and the value is evaluated as an opposite signed value, a calculation means, wherein demerit mark is evaluated based on a degree of inhibition by evaluating a side chain volume uninhibiting approach of α-carbons of the mutually corresponding amino acids within 5 angstroms to each other, and a calculation means, wherein a configuration of merit is evaluated based on accordance of backbone parallelism of peptide skeletons.
COPYRIGHT: (C)2004,JPO
摘要翻译：要解决的问题：通过有效设计对靶肽具有反应性并合成设计的肽的肽来提供新的活性肽对靶肽施加控制作用。肽解决方案：肽的评估系统包括计算装置，其中除了末端氨基酸之外的每个位置，肽的前后五个或几个氨基酸计算疏水性平均值，并且该值被评估为相反的符号值，计算装置，其中基于抑制程度通过评价彼此相互相对应的氨基酸的α-碳的侧链体积不受抑制的方法来评估不同标记，以及计算装置，其中配置基于肽骨架的骨架平行度来评价优点。版权所有（C）2004，JPO

IPRDB

热门服务

关于我们

友情链接

联系方式