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1. 发明申请

US20110270229A1 CATHETER 审中-公开
标题翻译：导管
公开(公告)号：US20110270229A1
公开(公告)日：2011-11-03
申请号：US13142390
申请日：2009-12-24
申请人： Hayao Tanaka , Kenichi Kanemasa , Yoichi Sakata
发明人： Hayao Tanaka , Kenichi Kanemasa , Yoichi Sakata
IPC分类号： A61M25/00
CPC分类号： A61M25/0147 , A61B1/0057 , A61M25/005 , A61M25/0053 , A61M25/0141 , A61M25/0152 , A61M2025/0161
摘要： A catheter (10) has a main lumen (20), and sub-lumens (30) each of which having a diameter smaller than that of the main lumen (20). The plurality of sub-lumens (30) are arranged along a circumference of the main lumen (20) in a discrete manner, and each of the sub-lumens (30) has an operating wire (40), fixed to the distal end section (15) of the catheter (10), laid therethrough in a freely slidable manner. By pulling the operating wire(s) (40) respectively laid through the sub-lumens (30), the distal end section (15) of the catheter (10) may be bent towards the pulled operating wire(s) (40) laid therethrough.
摘要翻译：导管（10）具有主管腔（20）和子腔（30），每个管腔的直径小于主管腔（20）的直径。多个子腔（30）以离散的方式沿着主腔（20）的圆周布置，并且每个子腔（30）具有操作线（40），固定到远端部（10）的导管（15）以可自由滑动的方式穿过其中。通过拉动分别铺设通过子腔（30）的操作线（40），导管（10）的远端部分（15）可以朝向被铺设的拉动的操作线（40）弯曲通过。

2. 发明申请

US20140020132A1 PLANTS HAVING INCREASED DESICCATION TOLERANCE, INCREASED DROUGHT TOLERANCE OR INCREASED WATER USE EFFICIENCY 有权
标题翻译：增加耐腐蚀性，增加耐旱性或提高使用效率的植物
公开(公告)号：US20140020132A1
公开(公告)日：2014-01-16
申请号：US13919300
申请日：2013-06-17
申请人： Ralph S. Quatrano , Yoichi Sakata , Izumi Yotsui
发明人： Ralph S. Quatrano , Yoichi Sakata , Izumi Yotsui
IPC分类号： C12N15/82
CPC分类号： C12N15/8273 , C07K14/415 , C12N15/8234 , C12N15/8293
摘要： A transgenic plant engineered to have increased desiccation tolerance, increased drought tolerance or increased water use efficiency, the plant transformed with an artificial DNA construct comprising a transcribable nucleic acid molecule encoding a polypeptide requiring both ABA and ABI3 to influence desiccation tolerance. Also provided are DNA constructs and methods of producing a transgenic plant engineered to have increased desiccation tolerance, increased drought tolerance or increased water use efficiency.
摘要翻译：工程改造为具有增加的干燥耐受性，增加的耐旱性或增加的水利用效率的转基因植物，所述植物用包含编码需要ABA和ABI3两者以影响干燥耐受性的多肽的可转录核酸分子的人造DNA构建体转化。还提供了DNA构建体和产生转基因植物的方法，所述转基因植物被工程化以具有增加的干燥耐受性，增加的耐旱性或增加的水利用效率。

3. 发明授权

US5352583A Human tissue plasminogen activator-human plasminogen activator inhibitor complex immunoassay and kit therefor 失效
标题翻译：人体组织纤溶酶原激活物 - 人纤溶酶原激活物抑制剂复合物免疫测定及其试剂盒
公开(公告)号：US5352583A
公开(公告)日：1994-10-04
申请号：US687867
申请日：1991-06-03
申请人： Yoichi Sakata , Kazuhiko Itoh , Shuichiro Hino , Ryoichi Hasegawa , Naomi Okamoto , Atsushi Noro , Toshinobu Murakami
发明人： Yoichi Sakata , Kazuhiko Itoh , Shuichiro Hino , Ryoichi Hasegawa , Naomi Okamoto , Atsushi Noro , Toshinobu Murakami
IPC分类号： G01N33/543 , G01N33/86 , G01N33/53
CPC分类号： G01N33/54393 , G01N33/54306 , G01N33/86 , G01N2333/8132 , G01N2333/9726 , Y10S435/962
摘要： A kit for the immunological assay of the human tissue plasminogen activator-human plasminogen activator inhibitor complex in a human specimen, which kit comprises(i) a monoclonal antibody (first antibody) against a human plasminogen activator inhibitor linked onto an insoluble solid carrier having a specular surface,(ii) a polyclonal antibody (second antibody) against a human tissue plasminogen activator labelled by an enzyme,(iii) a substrate and a reaction-discontinuing agent for the assay of the enzyme activity,(iv) a diluent, and(v) a detergent containing a nonionic surfactant having an HLB (Hydrophile Lipophile Balance) value of at least 16,and a method for the immunological assay of the above complex and a method for the immunological assay of the active human plasminogen activator inhibitor, respectively in a human specimen using this kit.
摘要翻译： PCT No.PCT / JP90 / 01269 Sec。 371日期1991年6月3日 102（e）日期1991年6月3日PCT 1990年10月2日PCT PCT。公开号WO91 / 05257 日期：1991年4月18日。用于人体标本中人组织纤溶酶原激活物 - 人纤溶酶原激活物抑制剂复合物的免疫测定试剂盒，该试剂盒包含（i）针对人类纤溶酶原激活物抑制剂的单克隆抗体（第一抗体）到具有镜面的不溶性固体载体上，（ii）针对由酶标记的人组织纤溶酶原激活物的多克隆抗体（第二抗体），（iii）用于测定酶活性的底物和反应中断剂，（iv）稀释剂，和（v）含有HLB（亲水亲油平衡）值至少为16的非离子表面活性剂的洗涤剂，以及上述复合物的免疫学测定方法和活性人纤溶酶原激活物抑制剂，分别在使用该试剂盒的人体标本中。

4. 发明申请

US20070275414A1 Method of Detecting Thrombosis by Measuring Von Willenbrand Factor-Cleaving Protease 有权
标题翻译：通过测量Von Willebrand因子切割蛋白酶检测血栓形成的方法
公开(公告)号：US20070275414A1
公开(公告)日：2007-11-29
申请号：US10584425
申请日：2004-12-22
申请人： Tomoko Ono , Kenji Soejima , Masaki Hirashima , Wataru Morikawa , Yoichi Sakata
发明人： Tomoko Ono , Kenji Soejima , Masaki Hirashima , Wataru Morikawa , Yoichi Sakata
IPC分类号： G01N33/573 , C12Q1/34
CPC分类号： G01N33/6893 , G01N2333/95 , G01N2800/222 , G01N2800/226 , G01N2800/32 , Y10S436/811 , Y10T436/106664
摘要： A method of detecting thrombosis or the degree of thrombophilia by measuring a von Willebrand factor cleaving protease, and a kit for detecting thrombosis or the degree of thrombophilia, comprising an antibody or a fragment thereof specifically binding to a von Willebrand factor-cleaving protease, are disclosed. The detection method and the detection kit have an excellent convenience, rapidity, and specificity.
摘要翻译：通过测量血管性血友病因子切割蛋白酶检测血栓形成或血栓形成的程度的方法，以及用于检测血栓形成或血栓形成的程度的试剂盒，其包含与血管性血友病变因子切割蛋白酶特异性结合的抗体或其片段，披露检测方法和检测试剂盒具有极佳的便利性，快速性和特异性。

5. 发明授权

US09000201B2 Adsorbent for removing metal compounds and method for same 有权
标题翻译：用于除去金属化合物的吸附剂及其方法
公开(公告)号：US09000201B2
公开(公告)日：2015-04-07
申请号：US13582700
申请日：2011-03-03
申请人： Yoichi Sakata , Haruto Wakabayashi , Kazutaka Yanagita
发明人： Yoichi Sakata , Haruto Wakabayashi , Kazutaka Yanagita
IPC分类号： C07F3/00 , C07F3/06 , C07F5/00 , C07F5/06
CPC分类号： C07F3/06 , C07F5/00 , C07F5/062
摘要： Disclosed are effective and simple adsorbents and methods of using the adsorbents for removing metal impurities generated during storage, transportation and supply of organometallic compounds. The disclosed adsorbents and methods provide for the easy and effective removal of the metallic impurities or compounds generated from decomposition of the organometallic compound during its transportation, storage, and supply. Namely, the disclosed adsorbents and methods permit the stable supply of a high purity organometallic compound desired in the semiconductor and photovoltaic cell.
摘要翻译：公开了有效和简单的吸附剂和使用吸附剂去除在储存，运输和供应有机金属化合物期间产生的金属杂质的方法。所公开的吸附剂和方法提供了容易且有效地除去在其运输，储存和供应期间由有机金属化合物分解产生的金属杂质或化合物。也就是说，所公开的吸附剂和方法允许在半导体和光伏电池中稳定地供应所需的高纯度有机金属化合物。

6. 发明授权

US08128755B2 Cleaning solvent and cleaning method for metallic compound 有权
标题翻译：金属化合物的清洗溶剂和清洗方法
公开(公告)号：US08128755B2
公开(公告)日：2012-03-06
申请号：US12817777
申请日：2010-06-17
申请人： Yoichi Sakata
发明人： Yoichi Sakata
IPC分类号： B08B3/04
CPC分类号： C11D11/0047 , C11D7/264 , C11D7/267 , C11D7/32 , C11D7/3209 , C11D7/5013 , C11D7/5022 , C23F1/10 , C23G5/032 , C23G5/036
摘要： Disclosed are cleaning solvents and cleaning methods for metallic compounds deposited on the equipment that supplies organometallic compounds to the manufacturing tool in the photovoltaic industry or the semiconductor industry. The cleaning solvents and the cleaning methods disclosed not only selectively remove the metallic compound without corroding the equipment, but also improve the ordinary cleaning process. Moreover, the cleaning solvents and the cleaning methods disclosed improve maintenance costs for the supply system because the equipment may be cleaned without being detached from the supply system.
摘要翻译：公开了用于向在光伏工业或半导体工业中的制造工具供应有机金属化合物的设备上沉积的金属化合物的清洁溶剂和清洁方法。所公开的清洗溶剂和清洁方法不仅选择性地除去金属化合物而不会腐蚀设备，而且还改善了普通的清洁工艺。此外，所公开的清洁溶剂和清洁方法提高了供应系统的维护成本，因为可以在不从供应系统脱离的情况下清洁设备。

7. 依法登记的发明

USH1148H Method of separating activated human protein C 失效
公开(公告)号：USH1148H
公开(公告)日：1993-03-02
申请号：US815870
申请日：1992-01-03
申请人： Kenji Wakabayashi , Yoshihiko Sumi , Yataro Ichikawa , Yoichi Sakata , Nobuo Aoki
发明人： Kenji Wakabayashi , Yoshihiko Sumi , Yataro Ichikawa , Yoichi Sakata , Nobuo Aoki
IPC分类号： C07K16/40 , C12N9/64
CPC分类号： C12N9/6464 , C07K16/40 , C12Y304/21069
摘要： A method of separating activated human protein C, which comprises bringing a mixture containing activated human protein C having a gamma-carboxyglutamic acid (Gla) domain in the presence of a calcium ion into contact with a fixed antibody comprising an insoluble carrier and fixed thereto an antibody to a complex of human protein C and a calcium ion bound to the Gla domain whereby the activated human protein C is captured by the fixed antibody in the form in which the calcium ion is bound to the Gla domain. A method is also provided for separating activated human protein C from a mixture containing human protein C and activated human protein C, which comprises bringing a first mixture containing human protein C and activated human protein C having a Gla domain into contact with a first fixed antibody comprising an insoluble carrier and fixed thereto a first antibody to human protein C but not to activated human protein C to form a second mixture substantially free from human protein C while the human protein C is captured by the first fixed antibody, and bringing the second mixture in the presence of a calcium ion into contact with a second fixed antibody comprising an insoluble carrier and fixed thereto a second antibody to a complex of human protein C and a calcium ion bound at the Gla domain, whereby the activated human protein C is captured by the second fixed antibody in the form in which the calcium ion is bound to the Gla domain.

8. 发明授权

US4902614A Monoclonal antibody to human protein C 失效
标题翻译：人类蛋白C的单克隆抗体
公开(公告)号：US4902614A
公开(公告)日：1990-02-20
申请号：US804255
申请日：1985-12-03
申请人： Kenji Wakabayashi , Yoshihiko Sumi , Yataro Ichikawa , Yoichi Sakata , Jun Mimuro , Nobuo Aoki
发明人： Kenji Wakabayashi , Yoshihiko Sumi , Yataro Ichikawa , Yoichi Sakata , Jun Mimuro , Nobuo Aoki
IPC分类号： C07K16/40 , G01N33/86
CPC分类号： C07K16/40 , G01N33/86 , G01N2333/96461 , Y10S435/815
摘要： A monoclonal antibody which is specific to human protein C which has calcium bound at the gammacarboxyglutamic acid(Gla) domain and does not recognize human protein C which is not bound to calcium at the Gla domain. The monoclonal antibody is used in an immunoassay method for determining human protein C having a Gla domain and in a method for recovering human protein C having a Gal domain.
摘要翻译：对人蛋白C特异性的单克隆抗体，其具有在γ-氨基谷氨酸（Gla）结构域处结合钙并且不识别在Gla结构域不与钙结合的人蛋白质C。单克隆抗体用于测定具有Gla结构域的人蛋白C的免疫测定方法和用于回收具有Gal结构域的人蛋白C的方法。

9. 发明授权

US08088624B2 Method of detecting thrombosis by measuring von Willenbrand factor-cleaving protease 有权
标题翻译：通过测量von Willebrand因子切割蛋白酶检测血栓形成的方法
公开(公告)号：US08088624B2
公开(公告)日：2012-01-03
申请号：US10584425
申请日：2004-12-22
申请人： Tomoko Ono , Kenji Soejima , Masaki Hirashima , Wataru Morikawa , Yoichi Sakata
发明人： Tomoko Ono , Kenji Soejima , Masaki Hirashima , Wataru Morikawa , Yoichi Sakata
IPC分类号： G01N33/86 , G01N33/53 , G01N33/00
CPC分类号： G01N33/6893 , G01N2333/95 , G01N2800/222 , G01N2800/226 , G01N2800/32 , Y10S436/811 , Y10T436/106664
摘要： A method of detecting thrombosis or the degree of thrombophilia by measuring a von Willebrand factor cleaving protease, and a kit for detecting thrombosis or the degree of thrombophilia, comprising an antibody or a fragment thereof specifically binding to a von Willebrand factor-cleaving protease, are disclosed. The detection method and the detection kit have an excellent convenience, rapidity, and specificity.
摘要翻译：通过测量血管性血友病因子切割蛋白酶检测血栓形成或血栓形成的程度的方法，以及用于检测血栓形成或血栓形成的程度的试剂盒，其包含与血管性血友病变因子切割蛋白酶特异性结合的抗体或其片段，披露检测方法和检测试剂盒具有极佳的便利性，快速性和特异性。

10. 发明申请

US20110214689A1 CLEANING SOLVENT AND CLEANING METHOD FOR METALLIC COMPOUND 有权
标题翻译：用于金属化合物的清洁溶剂和清洁方法
公开(公告)号：US20110214689A1
公开(公告)日：2011-09-08
申请号：US12817777
申请日：2010-06-17
申请人： Yoichi Sakata
发明人： Yoichi Sakata
IPC分类号： C23G1/02 , C11D3/60
CPC分类号： C11D11/0047 , C11D7/264 , C11D7/267 , C11D7/32 , C11D7/3209 , C11D7/5013 , C11D7/5022 , C23F1/10 , C23G5/032 , C23G5/036
摘要： Disclosed are cleaning solvents and cleaning methods for metallic compounds deposited on the equipment that supplies organometallic compounds to the manufacturing tool in the photovoltaic industry or the semiconductor industry. The cleaning solvents and the cleaning methods disclosed not only selectively remove the metallic compound without corroding the equipment, but also improve the ordinary cleaning process. Moreover, the cleaning solvents and the cleaning methods disclosed improve maintenance costs for the supply system because the equipment may be cleaned without being detached from the supply system.
摘要翻译：公开了用于向在光伏工业或半导体工业中的制造工具供应有机金属化合物的设备上沉积的金属化合物的清洁溶剂和清洁方法。所公开的清洗溶剂和清洁方法不仅选择性地除去金属化合物而不会腐蚀设备，而且还改善了普通的清洁工艺。此外，所公开的清洁溶剂和清洁方法提高了供应系统的维护成本，因为可以在不从供应系统脱离的情况下清洁设备。

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