专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4532041A Asymmetric polyimide reverse osmosis membrane, method for preparation of same and use thereof for organic liquid separations 失效
标题翻译：不对称聚酰亚胺反渗透膜，其制备方法及其在有机液体分离中的应用
公开(公告)号：US4532041A
公开(公告)日：1985-07-30
申请号：US564302
申请日：1983-12-22
申请人： Harry F. Shuey , Wankei Wan
发明人： Harry F. Shuey , Wankei Wan
IPC分类号： B01D71/64 , B01D13/04
CPC分类号： B01D71/64 , B01D61/025 , B01D61/10 , B01D63/10 , B01D67/0011
摘要： Asymmetric polyimide reverse osmosis membranes of high flux and selectivity for organic liquid separations are described. These membranes are prepared from undegraded polyimide by dissolving from 14-30 wt. % of the undegraded polymer in a dual solvent system comprising a polymer pro-solvent/anti-solvent wherein the pro-solvent is DMF and the anti-solvent is dioxane, wherein the ratio of anti-solvent/pro-solvent ranges from about 10:1 or more-1:1, preferably about 8:1-1.5:1, most preferably about 7:1-3:1; the polymer-solvent mixture is spread into a thin film of the desired thickness and permitted to evaporate for a time just sufficient to permit formation of an asymmetric dense active layer, i.e., within the range 2-120 seconds, preferably 2-60 seconds, most preferably 2-20 seconds before being immersed in a gelation bath.The membranes may be fabricated in the form of sheets, tubes, hollow fibers, etc.Mixtures of organic liquids, and especially mixtures of dewaxing solvents such as ketones, aromatic hydrocarbons and mixtures thereof, halogenated hydrocarbons such as dichloromethane, dichloroethane and mixtures of such halogenated hydrocarbons with ketones or aromatic hydrocarbons or other polar dewaxing solvents and dewaxed oils, are separated after completion of dewaxing operations, using the asymmetric polyimide reverse osmosis membrane described above.
摘要翻译：描述了对有机液体分离具有高通量和选择性的不对称聚酰亚胺反渗透膜。这些膜由未降解的聚酰亚胺由14-30wt。包含聚合物前溶剂/反溶剂的双溶剂系统中未降解的聚合物的％，其中前溶剂为DMF，反溶剂为二恶烷，其中反溶剂/前溶剂的比例为约10 ：1或更多-1：1，优选约8：1-1.5：1，最优选约7：1-3：1; 将聚合物 - 溶剂混合物扩散到所需厚度的薄膜中并允许蒸发一段时间，足以允许形成不对称的致密有源层，即在2-120秒，优选2-60秒的范围内，最优选2-20秒，然后浸入凝胶浴中。膜可以以片，管，中空纤维等的形式制造。有机液体的混合物，特别是脱蜡溶剂如酮，芳族烃及其混合物的混合物，卤代烃如二氯甲烷，二氯乙烷及其混合物使用上述的不对称聚酰亚胺反渗透膜，在脱蜡操作完成后，分离出具有酮或芳族烃的卤代烃或其它极性脱蜡溶剂和脱蜡油。

2. 发明申请

US20130143325A1 BIOCOMPATIBLE POLY (AMIC ACID) AND METHOD OF PREPARATION THEREOF 有权
标题翻译：生物成分（AMIC酸）及其制备方法
公开(公告)号：US20130143325A1
公开(公告)日：2013-06-06
申请号：US13639826
申请日：2011-04-08
申请人： Wankei Wan , Donna Padavan
发明人： Wankei Wan , Donna Padavan
IPC分类号： A61L27/34
CPC分类号： A61L27/34 , A61K47/34 , A61L27/18 , A61L27/54 , A61L31/06 , A61L31/10 , A61L31/16 , C12N5/069 , C12N11/08 , C08L77/00
摘要： A method is provided for the preparation of a poly(amic acid) in which ring opening polymerization is employed to react the monomers ethylenediaminetetraacetic dianhydride and paraphenylenediamine in an aprotic solvent. The resulting poly(amic acid) composition is suitable as a biocompatible material, such as a biomedical implant, implant coating material, tissue scaffold material, controlled release drug delivery vehicle, and cellular growth substrate.
摘要翻译：提供了一种用于制备聚（酰胺酸）的方法，其中使用开环聚合反应单体乙二胺四乙酸二酐和对苯二胺在非质子溶剂中。所得聚（酰胺酸）组合物适合作为生物相容性材料，例如生物医学植入物，植入物涂层材料，组织支架材料，控释药物递送载体和细胞生长底物。

3. 发明申请

US20120282584A1 SURGICAL TRAINING AIDS AND METHODS OF FABRICATION THEREOF 有权
标题翻译：手术训练艾滋病及其制作方法
公开(公告)号：US20120282584A1
公开(公告)日：2012-11-08
申请号：US13497670
申请日：2010-09-22
申请人： Leonardo Millon , Wankei Wan , Mackenzie Quantz
发明人： Leonardo Millon , Wankei Wan , Mackenzie Quantz
IPC分类号： G09B23/28 , B29C35/16
CPC分类号： B29C39/025 , B29C39/003 , B29C39/42 , B29K2029/04 , B29K2105/0061 , B29L2031/7532 , C08J3/075 , C08J2329/04 , G06F19/00 , G09B23/28 , G09B23/306
摘要： The present invention provides surgical training aids formed from hydrogels and adapted to exhibit realistic mechanical properties mimicking those of real organs. Surgical training aids are preferably fabricated by subjecting a concentration of polyvinyl alcohol to freeze-thaw cycles in a mold designed to approximate the shape of an organ, and process parameters are selected to tailor the mechanical properties of the formed hydrogel to those of the organ simulated by the surgical aid. The mechanical properties of the hydrogel forming the surgical training aid may be tailored by incorporating bacterial cellulose and by applying strain during hydrogel formation, thereby producing controlled anisotropy.
摘要翻译：本发明提供由水凝胶形成并适于显示模拟真实器官的机械特性的现实机械特性的外科训练辅助装置。手术训练辅助剂优选通过使聚乙烯醇的浓度在设计成接近器官形状的模具中进行冻融循环来制造，并且选择工艺参数以将所形成的水凝胶的机械性能与模拟的器官的机械性质通过手术辅助。形成外科训练辅助剂的水凝胶的机械性能可以通过掺入细菌纤维素并通过在水凝胶形成期间施加应变来调整，从而产生受控的各向异性。

4. 发明授权

US08940337B2 Transparent bacterial cellulose nanocomposite hydrogels 有权
标题翻译：透明细菌纤维素纳米复合水凝胶
公开(公告)号：US08940337B2
公开(公告)日：2015-01-27
申请号：US13520076
申请日：2010-12-23
申请人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
发明人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
IPC分类号： A61K9/50 , C08J3/24 , C08F2/00 , C08F2/44 , C08J3/075 , C08L1/02 , C08L33/06
CPC分类号： C08J3/24 , C08F2/00 , C08F2/44 , C08J3/075 , C08J2333/04 , C08L1/02 , C08L33/066 , Y10S977/773 , Y10S977/906 , Y10T428/31935
摘要： A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength. The disclosed polymer nanocomposite hydrogel and compositions pertain to hydrogel applications, particularly contact lenses and optic components for biosensor.
摘要翻译：提供了一种透明聚合物纳米复合材料水凝胶，其中聚合纳米复合材料水凝胶由水不溶性聚合物制成，即聚（甲基丙烯酸2-羟乙酯）（PHEMA）或/和交联的PHEMA和水不溶性纳米纤维，即细菌纤维素（BC）。公开了聚合物纳米复合材料水凝胶的合成路线。优选的聚合物纳米组合物通过在细菌纤维素存在下在超声波辅助下的HEMA单体的自由基聚合来生产，以增强细菌纤维素，引发剂和单体的混合。然后通过将干燥聚合物纳米复合物浸入水中形成聚合物纳米复合材料水凝胶。公开了一种高透光率聚合物纳米复合水凝胶，其优选BC载量小于0.1％，水含量为约40重量％，良好的机械完整性和强度。所公开的聚合物纳米复合材料水凝胶和组合物涉及水凝胶应用，特别是用于生物传感器的隐形眼镜和光学部件。

5. 发明授权

US08367089B2 Nanosilver coated bacterial cellulose 失效
公开(公告)号：US08367089B2
公开(公告)日：2013-02-05
申请号：US12226669
申请日：2007-04-24
申请人： Wankei Wan , Ganesh Guhados
发明人： Wankei Wan , Ganesh Guhados
IPC分类号： A01N25/08 , A01N59/16 , A61K9/70
CPC分类号： C08B15/05 , A61L15/28 , A61L15/46 , A61L2300/104 , A61L2300/404 , A61L2300/606 , A61L2300/624 , B82Y5/00 , C08B15/02 , D06M11/83 , D06M16/00 , D06M23/08 , Y10S977/762 , Y10S977/773 , Y10S977/788 , Y10S977/81 , Y10S977/904 , Y10T428/249921 , Y10T428/2927 , Y10T428/2958 , Y10T442/699 , C08L1/02
摘要： Nanosilver coated bacterial cellulose nanofiber and a method of producing the nanosilver coated bacterial cellulose nanofiber. The nanosilver coated bacterial cellulose nanofiber is produced by preparing a suspension of bacterial cellulose fibers, oxidizing bacterial cellulose fibers; adding the thio-group to the polymer backbone; reacting the resulting product with silver proteinate and enhancing the nanosilver particle size. The nanosilver coated bacterial cellulose nanofibers exhibit antimicrobial properties.

6. 发明申请

US20130011385A1 TRANSPARENT BACTERIAL CELLULOSE NANOCOMPOSITE HYDROGELS 有权
标题翻译：透明细菌纤维素纳米复合物水凝胶
公开(公告)号：US20130011385A1
公开(公告)日：2013-01-10
申请号：US13520076
申请日：2010-12-23
申请人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
发明人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
IPC分类号： C08L33/14 , A61K38/02 , A61K31/715 , A61K39/395 , B32B27/30 , A61K47/32 , A61K48/00 , B82Y30/00
CPC分类号： C08J3/24 , C08F2/00 , C08F2/44 , C08J3/075 , C08J2333/04 , C08L1/02 , C08L33/066 , Y10S977/773 , Y10S977/906 , Y10T428/31935
摘要： A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength. The disclosed polymer nanocomposite hydrogel and compositions pertain to hydrogel applications, particularly contact lenses and optic components for biosensor.
摘要翻译：提供了一种透明聚合物纳米复合材料水凝胶，其中聚合纳米复合材料水凝胶由水不溶性聚合物制成，即聚（甲基丙烯酸2-羟乙酯）（PHEMA）或/和交联的PHEMA和水不溶性纳米纤维，即细菌纤维素（BC）。公开了聚合物纳米复合材料水凝胶的合成路线。优选的聚合物纳米组合物通过在细菌纤维素存在下在超声波辅助下的HEMA单体的自由基聚合来生产，以增强细菌纤维素，引发剂和单体的混合。然后通过将干燥聚合物纳米复合物浸入水中形成聚合物纳米复合材料水凝胶。公开了一种高透光率聚合物纳米复合水凝胶，其优选BC载量小于0.1％，水含量为约40重量％，良好的机械完整性和强度。所公开的聚合物纳米复合材料水凝胶和组合物涉及水凝胶应用，特别是用于生物传感器的隐形眼镜和光学部件。

7. 发明申请

US20100183699A1 COMPOSITIONS AND METHODS TO CROSS LINK POLYMER FIBERS 审中-公开
标题翻译：组合物和交联聚合物纤维的方法
公开(公告)号：US20100183699A1
公开(公告)日：2010-07-22
申请号：US12691020
申请日：2010-01-21
申请人： Wankei Wan , Mina Mekhail
发明人： Wankei Wan , Mina Mekhail
IPC分类号： C07D311/02 , C09K3/00 , C08L77/00 , C07K1/00 , C07H1/00 , C08K5/1545 , C12N5/00 , A61K38/17 , A61F2/02 , A61K38/39 , A61P17/00
CPC分类号： C07K1/14 , A61K31/352 , A61L27/24 , A61L27/50 , A61L2400/12 , C08L77/00 , C08L89/00 , D01D5/0038
摘要： Novel compositions comprising genipin for cross-linking polymer fibers, are provided. In aspects of the invention the compositions further comprise a solvent system, wherein said solvent system comprises alcohol solvent and water. The genipin-based compositions are useful in methods for promoting the stabilization of fibers in an aqueous environment, and in tissue engineering. The novel genipin-based composition is also useful in methods of treating dermatological conditions.
摘要翻译：提供了包含用于交联聚合物纤维的京尼平的新型组合物。在本发明的方面，组合物还包含溶剂体系，其中所述溶剂体系包含醇溶剂和水。基于京尼平的组合物可用于在水性环境中以及在组织工程中促进纤维的稳定化的方法。基于新奇基蛋白的组合物也可用于治疗皮肤病学的方法。

8. 发明授权

US08956638B2 Biocompatible poly (amic acid) and method of preparation thereof 有权
标题翻译：生物相容性聚（酰胺酸）及其制备方法
公开(公告)号：US08956638B2
公开(公告)日：2015-02-17
申请号：US13639826
申请日：2011-04-08
申请人： Wankei Wan , Donna Padavan
发明人： Wankei Wan , Donna Padavan
IPC分类号： A61L27/34 , A61K47/34 , A61L31/10 , C08G69/26 , C08G69/28 , A61L27/18 , A61L27/54 , A61L31/06 , A61L31/16 , C12N5/071 , C12N11/08
CPC分类号： A61L27/34 , A61K47/34 , A61L27/18 , A61L27/54 , A61L31/06 , A61L31/10 , A61L31/16 , C12N5/069 , C12N11/08 , C08L77/00
摘要： A method is provided for the preparation of a poly(amic acid) in which ring opening polymerization is employed to react the monomers ethylenediaminetetraacetic dianhydride and paraphenylenediamine in an aprotic solvent. The resulting poly(amic acid) composition is suitable as a biocompatible material, such as a biomedical implant, implant coating material, tissue scaffold material, controlled release drug delivery vehicle, and cellular growth substrate.
摘要翻译：提供了一种用于制备聚（酰胺酸）的方法，其中使用开环聚合反应单体乙二胺四乙酸二酐和对苯二胺在非质子溶剂中。所得聚（酰胺酸）组合物适合作为生物相容性材料，例如生物医学植入物，植入物涂层材料，组织支架材料，控释药物递送载体和细胞生长底物。

9. 发明申请

US20090214623A1 ANISOTROPIC HYDROGELS 有权
标题翻译：各向异性水凝胶
公开(公告)号：US20090214623A1
公开(公告)日：2009-08-27
申请号：US11909880
申请日：2006-03-30
申请人： Wankei Wan , Leonardo E. Millon , Hadi Mohammadi
发明人： Wankei Wan , Leonardo E. Millon , Hadi Mohammadi
IPC分类号： A61K9/70 , A61K9/10 , A61K31/727 , A61K35/12
CPC分类号： C08L29/04 , A61B17/2251 , A61F7/10 , A61F2007/0098 , A61L15/24 , A61L15/44 , A61L15/60 , A61L15/62 , A61L27/16 , A61L27/52 , A61L27/54 , A61L29/041 , A61L29/145 , A61L29/16 , A61L31/048 , A61L31/145 , A61L31/16 , A61L2300/00 , C08F8/00 , C08J3/075 , C08J2329/04 , F16L9/00 , C08F16/06
摘要： The invention relates to an anisotropic hydrogel and a method of producing the anisotropic hydrogel. The hydrogel exhibiting anisotropic properties is poly(vinyl alcohol) produced by preparing a solution of poly(vinyl alcohol) with a pre-selected concentration, thermally cycling the solution by freezing and thawing, stretching the hydrogel and thermally cycling the hydrogel at least one more time The anisotropic hydrogel is used for tissue replacement and reconstruction, bioagent entrapment and delivery, in preparing ultrasound or radiofrequency thermal therapy transmission pads and substitutes for ice bags, as denture base, in soft contact lens material, for wound covering bandages and phantoms for medical-related use.
摘要翻译：本发明涉及各向异性水凝胶以及各向异性水凝胶的制造方法。显示各向异性性质的水凝胶是通过制备具有预选浓度的聚（乙烯醇）溶液而制备的聚（乙烯醇），通过冷冻和解冻热循环溶液，拉伸水凝胶并热水循环水凝胶至少一种时间各向异性水凝胶用于组织置换和重建，生物捕获和递送，在制备超声波或射频热疗传播垫和替代冰袋，作为义齿基底，软隐形眼镜材料中，用于伤口覆盖绷带和医疗用体相关使用。

10. 发明授权

US4853129A Modified regenerated cellulose membrane for non-aqueous separations 失效
标题翻译：改性再生纤维素膜用于非水分离
公开(公告)号：US4853129A
公开(公告)日：1989-08-01
申请号：US50771
申请日：1987-05-18
申请人： Wankei Wan
发明人： Wankei Wan
IPC分类号： C10G73/00
CPC分类号： C10G73/00 , B01D61/10 , B01D67/0093 , B01D71/10 , B01D2323/30 , B01D2323/36 , B01D2325/20
摘要： Regenerated cellulose membranes used for the separation of organic liquids, for example, ketone dewaxing solvents from dewaxed oil or NMP extraction solvents from extract, have their solute rejection capability enhanced by chemical modification by contacting said membrane with a bifunctional reagent that is reactive with the hydroxy groups in the anhydroglucose units of the regenerated cellulose polymer. The reaction of the bifunctional reagent with the hydroxy groups in the polymer results in the crosslinking of the polymer which, in turn, results in the improvement of the membrane's selectivity in organic liquid separations applications.
摘要翻译：用于分离有机液体的再生纤维素膜，例如脱蜡油的酮脱蜡溶剂或萃取液中的NMP提取溶剂，通过使所述膜与与羟基反应的双官能试剂接触，通过化学改性增强其溶质排除能力在再生纤维素聚合物的脱水葡萄糖单元中的基团。双官能试剂与聚合物中的羟基的反应导致聚合物的交联，其又导致膜在有机液体分离应用中的选择性的改善。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式