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1. 发明授权

US08940337B2 Transparent bacterial cellulose nanocomposite hydrogels 有权
标题翻译：透明细菌纤维素纳米复合水凝胶
公开(公告)号：US08940337B2
公开(公告)日：2015-01-27
申请号：US13520076
申请日：2010-12-23
申请人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
发明人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
IPC分类号： A61K9/50 , C08J3/24 , C08F2/00 , C08F2/44 , C08J3/075 , C08L1/02 , C08L33/06
CPC分类号： C08J3/24 , C08F2/00 , C08F2/44 , C08J3/075 , C08J2333/04 , C08L1/02 , C08L33/066 , Y10S977/773 , Y10S977/906 , Y10T428/31935
摘要： A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength. The disclosed polymer nanocomposite hydrogel and compositions pertain to hydrogel applications, particularly contact lenses and optic components for biosensor.
摘要翻译：提供了一种透明聚合物纳米复合材料水凝胶，其中聚合纳米复合材料水凝胶由水不溶性聚合物制成，即聚（甲基丙烯酸2-羟乙酯）（PHEMA）或/和交联的PHEMA和水不溶性纳米纤维，即细菌纤维素（BC）。公开了聚合物纳米复合材料水凝胶的合成路线。优选的聚合物纳米组合物通过在细菌纤维素存在下在超声波辅助下的HEMA单体的自由基聚合来生产，以增强细菌纤维素，引发剂和单体的混合。然后通过将干燥聚合物纳米复合物浸入水中形成聚合物纳米复合材料水凝胶。公开了一种高透光率聚合物纳米复合水凝胶，其优选BC载量小于0.1％，水含量为约40重量％，良好的机械完整性和强度。所公开的聚合物纳米复合材料水凝胶和组合物涉及水凝胶应用，特别是用于生物传感器的隐形眼镜和光学部件。

2. 发明申请

US20130011385A1 TRANSPARENT BACTERIAL CELLULOSE NANOCOMPOSITE HYDROGELS 有权
标题翻译：透明细菌纤维素纳米复合物水凝胶
公开(公告)号：US20130011385A1
公开(公告)日：2013-01-10
申请号：US13520076
申请日：2010-12-23
申请人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
发明人： Xinsheng Li , Wankei Wan , Chandrakant J. Panchal
IPC分类号： C08L33/14 , A61K38/02 , A61K31/715 , A61K39/395 , B32B27/30 , A61K47/32 , A61K48/00 , B82Y30/00
CPC分类号： C08J3/24 , C08F2/00 , C08F2/44 , C08J3/075 , C08J2333/04 , C08L1/02 , C08L33/066 , Y10S977/773 , Y10S977/906 , Y10T428/31935
摘要： A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength. The disclosed polymer nanocomposite hydrogel and compositions pertain to hydrogel applications, particularly contact lenses and optic components for biosensor.
摘要翻译：提供了一种透明聚合物纳米复合材料水凝胶，其中聚合纳米复合材料水凝胶由水不溶性聚合物制成，即聚（甲基丙烯酸2-羟乙酯）（PHEMA）或/和交联的PHEMA和水不溶性纳米纤维，即细菌纤维素（BC）。公开了聚合物纳米复合材料水凝胶的合成路线。优选的聚合物纳米组合物通过在细菌纤维素存在下在超声波辅助下的HEMA单体的自由基聚合来生产，以增强细菌纤维素，引发剂和单体的混合。然后通过将干燥聚合物纳米复合物浸入水中形成聚合物纳米复合材料水凝胶。公开了一种高透光率聚合物纳米复合水凝胶，其优选BC载量小于0.1％，水含量为约40重量％，良好的机械完整性和强度。所公开的聚合物纳米复合材料水凝胶和组合物涉及水凝胶应用，特别是用于生物传感器的隐形眼镜和光学部件。

3. 发明授权

US4355109A Microbiological production of novel biosurfactants 失效
标题翻译：新生物表面活性剂的微生物生产
公开(公告)号：US4355109A
公开(公告)日：1982-10-19
申请号：US142779
申请日：1980-04-22
申请人： James E. Zajic , Donald F. Gerson , Richard K. Gerson , Chandrakant J. Panchal
发明人： James E. Zajic , Donald F. Gerson , Richard K. Gerson , Chandrakant J. Panchal
IPC分类号： B03D1/004 , C12P1/04
CPC分类号： C12P1/04 , B03D1/004 , Y10S435/843
摘要： Newly isolated microbes of the genera Arthrobacter-Corynebacterium-Nocardia as represented by Corynebacteria Salvinicum strain SFC, produce substantial quantities of materials having outstanding surfactant properties, when grown on carbon supplying substrates under fermentation conditions.
摘要翻译：当发酵条件下生长在碳供应底物上时，新生分离的棒状杆菌 - 诺卡氏菌属（Corynebacteria Salvinicum）SFC表示的微生物产生大量具有优异表面活性剂特性的材料。

4. 发明授权

US4772556A Genetically stable allopolyploid somatic fusion product useful in the production of fuel alcohols 失效
标题翻译：用于生产燃料醇的遗传稳定的异倍体体细胞融合产物
公开(公告)号：US4772556A
公开(公告)日：1988-09-20
申请号：US883421
申请日：1986-07-14
申请人： Graham G. Stewart , Ingeborg Russell , Chandrakant J. Panchal
发明人： Graham G. Stewart , Ingeborg Russell , Chandrakant J. Panchal
IPC分类号： C12N1/18 , C12N15/04 , C12P7/06 , C12N15/00 , C12R1/85
CPC分类号： C12N15/04 , C12N1/18 , C12P7/06 , Y02E50/17 , Y10S435/94
摘要： The present invention relates to a stable, allopolyploid, somatic fusion product useful in the fermentation arts and especially in the production of fuel alcohols. More particularly, the present invention relates to a novel allopolyploid yeast strain, Saccharomyces diastaticus NCYC 1460, which is the product of the spheroplast fusion of:(a) a hybrid, diploid strain of Sacch. diastaticus; and(b) a fusion partner which is a polyploid brewing yeast strain of the species Saccharomyces uvarum (carlsbergensis).The fusion product of the present invention is capable of an enhanced rate of fermentation and a generally higher degree of final attenuation than is typical of either of the fusion partners. Moreover the fusion product also evidences enhanced osmo- and thermo-tolerances and its multiple, non-allelic DEX gene complement renders the organism well suited to the fermentation of substrates containing dextrins and oligosaccharides.
摘要翻译：本发明涉及一种用于发酵领域，特别是生产燃料醇的稳定的异倍体体细胞融合产物。更具体地说，本发明涉及一种新型异折麦酵母菌株，Saccharomyces diastaticus NCYC 1460，它是以下成分之一：（a）Sacchus杂交二倍体菌株的原生质体融合物的产物。 ; us 和（b）融合配偶体，其是酿酒酵母（Carlsbergensis）的多倍体酿造酵母菌株。本发明的融合产物能够比两种融合伴侣的典型特征提高发酵速率和一般较高程度的最终衰减。此外，融合产物还证明增强的渗透和热耐受性及其多重非等位基因DEX基因补体使得生物体非常适合含有糊精和寡糖的底物的发酵。

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