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1. 发明授权

EP1569556B1 FULL FIELD MAMMOGRAPHY WITH TISSUE EXPOSURE CONTROL, TOMOSYNTHESIS, AND DYNAMIC FIELD OF VIEW PROCESSING 有权
标题翻译：利用组织的曝光控制，X射线照相组合和动态视觉场处理满场乳腺癌图像
公开(公告)号：EP1569556B1
公开(公告)日：2012-04-25
申请号：EP03783784.6
申请日：2003-11-26
申请人： HOLOGIC, INC. , Jing, Zhenxue , Hitzke, Georgia , Kennedy, Donald , Smith, Andrew , Stein, Jay A.
发明人： JING, Zhenxue , HITZKE, Georgia , KENNEDY, Donald , SMITH, Andrew , STEIN, Jay, A.
IPC分类号： A61B6/04 , A61B6/00 , A61B3/00
CPC分类号： A61B6/502 , A61B6/025 , A61B6/06 , A61B6/4035 , A61B6/4291 , A61B6/482
摘要： A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast (20 and 22) and of breast density (26, 28, 30 and 32) to automatically derive one or more technic factors (24). The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid (12d) on the x-ray source (12a) and also maintains the field of view of the x-ray receptor (12c). Finally, the system finds an outline that forms a reduced field of view (48) that still encompasses the breast in the image (46), and uses for further processing, transmission or archival storage the data within said reduced field of view (48).

2. 发明公开

EP1569556A1 FULL FIELD MAMMOGRAPHY WITH TISSUE EXPOSURE CONTROL, TOMOSYNTHESIS, AND DYNAMIC FIELD OF VIEW PROCESSING 有权
标题翻译：利用组织的曝光控制，断层合成和动态视觉场处理满场乳腺癌图像
公开(公告)号：EP1569556A1
公开(公告)日：2005-09-07
申请号：EP03783784.6
申请日：2003-11-26
申请人： HOLOGIC, INC. , Jing, Zhenxue , Hitzke, Georgia , Kennedy, Donald , Smith, Andrew , Stein, Jay A.
发明人： JING, Zhenxue , HITZKE, Georgia , KENNEDY, Donald , SMITH, Andrew , STEIN, Jay, A.
IPC分类号： A61B6/04
CPC分类号： A61B6/502 , A61B6/025 , A61B6/06 , A61B6/4035 , A61B6/4291 , A61B6/482
摘要： A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast (20 and 22) and of breast density (26, 28, 30 and 32) to automatically derive one or more technic factors (24). The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid (12d) on the x-ray source (12a) and also maintains the field of view of the x-ray receptor (12c). Finally, the system finds an outline that forms a reduced field of view (48) that still encompasses the breast in the image (46), and uses for further processing, transmission or archival storage the data within said reduced field of view (48).

3. 发明申请

WO2004049949A1 FULL FIELD MAMMOGRAPHY WITH TISSUE EXPOSURE CONTROL, TOMOSYNTHESIS, AND DYNAMIC FIELD OF VIEW PROCESSING 审中-公开
标题翻译：具有组织接触控制，动力学和动态视野处理领域的全场动画
公开(公告)号：WO2004049949A1
公开(公告)日：2004-06-17
申请号：PCT/US2003/037763
申请日：2003-11-26
申请人： HOLOGIC, INC. , JING, Zhenxue , HITZKE, Georgia , KENNEDY, Donald , SMITH, Andrew , STEIN, Jay, A.
发明人： JING, Zhenxue , HITZKE, Georgia , KENNEDY, Donald , SMITH, Andrew , STEIN, Jay, A.
IPC分类号： A61B6/04
CPC分类号： A61B6/502 , A61B6/025 , A61B6/06 , A61B6/4035 , A61B6/4291 , A61B6/482
摘要： A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast (20 and 22) and of breast density (26, 28, 30 and 32) to automatically derive one or more technic factors (24). The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid (12d) on the x-ray source (12a) and also maintains the field of view of the x-ray receptor (12c). Finally, the system finds an outline that forms a reduced field of view (48) that still encompasses the breast in the image (46), and uses for further processing, transmission or archival storage the data within said reduced field of view (48).
摘要翻译：依赖于压缩和固定的乳房（20和22）的厚度估计和乳房密度（26,28,30和32）的自动导出一个或多个技术因素（24）的组织暴露控制的乳房摄影系统。该系统进一步使用将防散射栅格（12d）的焦点保持在x射线源（12a）上并且还保持x射线受体（12c）的视野的断层合成装置。最后，系统找到形成仍然包含图像（46）中的乳房的缩小视场（48）的轮廓，并且用于进一步处理，传输或存档在所述缩小视场（48）内的数据，。

4. 发明申请

WO2009042597A1 DEDICATED BREAST RADIATION IMAGING/THERAPY SYSTEM 审中-公开
标题翻译：专用乳腺放射成像/治疗系统
公开(公告)号：WO2009042597A1
公开(公告)日：2009-04-02
申请号：PCT/US2008/077381
申请日：2008-09-23
申请人： HOLOGIC, INC. , BROOKS, Kenneth , STEIN, Jay, A. , SMITH, Andrew, P.
发明人： BROOKS, Kenneth , STEIN, Jay, A. , SMITH, Andrew, P.
IPC分类号： A61B6/04
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/0414 , A61B6/4258 , A61B6/502 , A61N5/10 , A61N5/1081 , A61N5/1082 , A61N2005/1058 , A61N2005/1061 , A61N2005/1087 , A61N2005/1097
摘要： System, apparatus and methods specialized for breast and related tissue radiation therapy and imaging of a prone patient but also usable for supine patient if desired or needed. A special treatment radiation source such as a LINAC unit generates radiation of types and energy ranges specifically matched to breast tissue. Any one or more of several imaging technologies may be used to localize the tissue to be irradiated and to generate information for therapy planning, adjustment, and verification.
摘要翻译：专门用于乳房和相关组织放射治疗的系统，设备和方法以及倾向患者的成像，但如果需要或需要，也可用于仰卧患者。诸如LINAC单元之类的特殊处理辐射源产生与乳房组织特别匹配的类型和能量范围的辐射。可以使用几种成像技术中的一种或多种来定位待照射的组织并产生用于治疗计划，调整和验证的信息。

5. 发明申请

WO2008019125A3 ORTHOVOLTAGE BREAST RADIATION THERAPY 审中-公开
公开(公告)号：WO2008019125A3
公开(公告)日：2008-02-14
申请号：PCT/US2007/017470
申请日：2007-08-03
申请人： HOLOGIC, INC. , SMITH, Andrew , STEIN, Jay, A.
发明人： SMITH, Andrew , STEIN, Jay, A.
IPC分类号： A61N5/10
摘要： X-ray breast imaging and therapy can be carried out in a single compression of the breast using the same x-ray source, can be repeated at different orientation of the x-ray beam relative to the breast, and can be based on the geometry of a known mammography system, or a known breast tomosynthesis system, or a known prone table breast biopsy system.

6. 发明申请

WO2007095330A2 BREAST BIOPSY AND NEEDLE LOCALIZATION USING TOMOSYNTHESIS SYSTEMS 审中-公开
标题翻译：使用酪氨酸酶系统进行乳腺生物学和针状局部化
公开(公告)号：WO2007095330A2
公开(公告)日：2007-08-23
申请号：PCT/US2007/004006
申请日：2007-02-15
申请人： HOLOGIC, INC. , FREITAS, Kenneth, DE. , SHAW, Ian, M. , LAVIOLA, John , NIKLASON, Loren, Thomas , WU, Tao , MARK, Joseph, L. , MILLER, Michael, E. , STEIN, Jay, A. , SMITH, Andrew, P.
发明人： HOLOGIC, INC. , FREITAS, Kenneth, DE. , SHAW, Ian, M. , LAVIOLA, John , NIKLASON, Loren, Thomas , WU, Tao , MARK, Joseph, L. , MILLER, Michael, E. , STEIN, Jay, A. , SMITH, Andrew, P.
CPC分类号： A61B6/025 , A61B6/0435 , A61B6/12 , A61B6/463 , A61B6/466 , A61B6/467 , A61B6/469 , A61B6/502 , A61B10/0233 , A61B10/0275 , A61B90/11 , A61B90/17 , A61B2090/376
摘要： Methods, devices, apparatuses and systems are disclosed for performing mammography, such as utilizing tomosynthesis in combination with breast biopsy.
摘要翻译：公开了用于执行乳房X线照相术的方法，装置，装置和系统，例如与乳房活组织检查结合使用断层合成术。

7. 发明申请

WO2006055830A2 MATCHING GEOMETRY GENERATION AND DISPLAY OF MAMMOGRAMS AND TOMOSYNTHESIS IMAGES 审中-公开
标题翻译：匹配几何生成和显示的动物和图像的图像
公开(公告)号：WO2006055830A2
公开(公告)日：2006-05-26
申请号：PCT/US2005/041941
申请日：2005-11-15
申请人： HOLOGIC, INC. , REN, Baorui , RUTH, Christopher , SMITH, Andrew, P. , WILSON, Kevin , STEIN, Jay, A.
发明人： REN, Baorui , RUTH, Christopher , SMITH, Andrew, P. , WILSON, Kevin , STEIN, Jay, A.
IPC分类号： G06K9/00
CPC分类号： G06K9/6201 , A61B6/502 , G06T3/0006 , G06T7/30 , G06T11/006 , G06T11/60 , G06T2207/10081 , G06T2207/30068
摘要： A method and a system for using tomosynthesis projection images of a patient's breast to reconstruct slice tomosynthesis images such that anatomical structures that appear superimposed in a mammogram are at conforming locations in the reconstructed images.
摘要翻译：一种用于使用患者乳房的断层合成投影图像来重构切片断层合成图像的方法和系统，使得出现叠加在乳房X光检查图中的解剖结构处于重构图像中的符合位置。

8. 发明申请

WO2023028532A1 SYSTEMS AND METHODS FOR MEASURING MOVEMENT OF A COMPRESSED BREAST 审中-公开
公开(公告)号：WO2023028532A1
公开(公告)日：2023-03-02
申请号：PCT/US2022/075419
申请日：2022-08-24
申请人： HOLOGIC, INC.
发明人： REN, Baorui , STEIN, Jay, A.
IPC分类号： A61B6/04 , A61B6/00
摘要： A method of imaging a breast compressed with a paddle including a foam compressive element. The method emits an x-ray energy from an x-ray source towards the breast and the foam compressive element and a marker disposed adjacent the foam compressive element. The x-ray energy is emitted over a predetermined time period. The marker includes a physical characteristic. The x-ray energy is detected at a detector disposed opposite the breast from the x-ray source. An image of the compressed breast and the marker is generated based on the detected x-ray energy. The marker in the generated image includes an image characteristic associated with the physical characteristic. The image characteristic is compared to the physical characteristic. A signal is sent when the image characteristic deviates from the physical characteristic by a threshold.

9. 发明申请

WO2003021629A1 DIGITAL FLAT PANEL X-RAY RECEPTOR POSITIONING IN DIAGNOSTIC RADIOLOGY 审中-公开
标题翻译：数字平板X射线摄影定位诊断放射学
公开(公告)号：WO2003021629A1
公开(公告)日：2003-03-13
申请号：PCT/US2002/027604
申请日：2002-08-28
申请人： HOLOGIC, INC.
发明人： SMITH, Andrew, P. , STEIN, Jay, A. , WILSON, Kevin, E. , CABRAL, Richard, E. , ROSSI, Remo , MILLER, James, D.
IPC分类号： H01J31/50
CPC分类号： A61B6/0457 , A61B6/06 , A61B6/105 , A61B6/4233 , A61B6/4291 , A61B6/4464 , A61B6/488 , A61B6/547 , A61B6/56 , A61B6/563 , A61B6/583 , A61B2560/0271
摘要： A digital, flat panel, two-dimensional x-ray detector (34) moves reliably, safely and conveniently to a variety of positions for different x-ray protocols for a standing, sitting or recumbent patient. The system makes it practical to use the same detector for a number or protocols that otherwise may require different equipment, and takes advantage of desirable characteristics of flat panel digital detectors while alleviating the effects of less desirable characteristics such as high cost, weight and fragility of such detectors.
摘要翻译：数字平板二维X射线检测器（34）可靠地，安全且方便地移动到用于不同x射线方案的各种位置，用于站立，坐着或卧床的患者。该系统使得使用相同的检测器用于可能需要不同设备的数量或协议，并且利用平板数字检测器的期望特性，同时减轻不太理想的特性的影响，例如高成本，重量和脆弱性这样的检测器。

10. 发明申请

WO1988000697A1 BONE DENSITOMETER 审中-公开
标题翻译：骨密度测定仪
公开(公告)号：WO1988000697A1
公开(公告)日：1988-01-28
申请号：PCT/US1987001659
申请日：1987-07-14
申请人： HOLOGIC, INC.
发明人： HOLOGIC, INC. , STEIN, Jay, A.
IPC分类号： G01N23/04
CPC分类号： G01N23/083 , A61B6/405 , A61B6/482 , A61B6/505 , H05G1/26 , H05G1/46
摘要： In an x-ray bone densitometer, a rotating device (12) carries a calibration material through the beam. The densitometer uses an x-ray tube (1) operated at two different voltages to generate a pencil beam (8). An integrating detector (5) is timed to integrate the detector signal of the patient-attenuated beam over each pulse, the signals are converted to digital values and a digital computer (13) converts the set of values produced by the raster scan into a representation of the bone density of the patient. Multiple reference detectors (7, 8) with differing absorbers (9, 10) are used by the system to continuously correct for variation in x-ray tube voltage and current. Calibration is accomplished by the digital computer on the basis of passing the pencil beam through known bone-representing substance as the densitometer scans portions of the patient (4) having bone and adjacent portions having only flesh.
摘要翻译：在x射线骨密度计中，旋转装置（12）通过束携带校准材料。密度计使用在两个不同电压下操作的X射线管（1）来产生笔杆（8）。积分检测器（5）被定时以将每个脉冲上的患者衰减波束的检测器信号进行积分，信号被转换成数字值，并且数字计算机（13）将由光栅扫描产生的一组值转换为表示的患者的骨密度。系统使用具有不同吸收体（9,10）的多个参考探测器（7,8）来连续校正X射线管电压和电流的变化。基于通过已知的骨代表物质使铅笔束通过已知的骨代表物质进行校准，因为密度计扫描具有骨骼的患者（4）的部分和仅具有肉体的相邻部分。

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