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1. 发明授权

US3862112A Alkali extraction of microbial cellular proteins at high temperature 失效
标题翻译： ALKALI在高温下提取微生物细胞蛋白
公开(公告)号：US3862112A
公开(公告)日：1975-01-21
申请号：US28779372
申请日：1972-09-11
申请人： HITACHI LTD
发明人： ISHIDA MASAHIKO , OGURI YOSHITAKA , MUROI TADASHI , SHIMIZU NORIO
IPC分类号： A23J1/18 , A23J1/00 , C12N1/00 , C12P21/00 , C07G7/00
CPC分类号： A23J1/008 , C12N1/005 , Y10S435/822 , Y10S435/911 , Y10S435/921 , Y10S435/923 , Y10S435/946 , Y10S435/947 , Y10S530/82 , Y10S530/822 , Y10S530/825
摘要： A method of extracting microbial cellular proteins which comprises subjecting an aqueous dispersion containing microbial cells to an extraction in the presence of about 0.1 to about 1% by weight of NaOH or KOH at a temperature of about 100* to about 200* C. According to this method, microbial cellular proteins can be effectively extracted in high yields.
摘要翻译：一种提取微生物细胞蛋白质的方法，其包括在约100至约200℃的温度下，使含有微生物细胞的水性分散体在约0.1至约1重量％的NaOH或KOH存在下进行萃取。

2. 发明专利

DE3688311T2 未知
公开(公告)号：DE3688311T2
公开(公告)日：1993-10-28
申请号：DE3688311
申请日：1986-10-13
申请人： HITACHI LTD
发明人： SHIMIZU NORIO , FUKUZONO SHINICHI , NISHIMURA NOBUKO , FUJIMORI KIYOSHI , ODAWARA YOJI
IPC分类号： C12N15/09 , C12M1/12 , C12N1/00 , C12N1/10 , C12N1/16 , C12N1/20 , C12N1/21 , C12N1/38 , C12N5/00 , C12N5/10 , C12N9/38 , C12N15/00 , C12N15/70 , C12P1/00 , C12R1/19 , C12N15/56
摘要： This invention relates to an efficient process for culturing recombinant cells which comprises a step of removing a cell proliferation inhibiting substance and/or a substance which inhibits induction of the desired product and a step of inducing production of the desired product.

4. 发明专利

DE69010529D1 未知
公开(公告)号：DE69010529D1
公开(公告)日：1994-08-18
申请号：DE69010529
申请日：1990-03-14
申请人： HITACHI LTD
发明人： TAKEUCHI KOUJI , KAWAGUCHI HIDEO , ISHIBASHI TADASHI , SHIMIZU NORIO
IPC分类号： C12M1/36 , C12M3/02 , C12N5/00
摘要： The invention relates to a method and an apparatus for cultivating animal cells. Cultures of animal cells stable for a long time are accomplished by calculating the ratio (L/G) of the amount of lactic acid formed by the cultivation of the animal cells to the amount of glucose consumed thereby, within a predetermined time period determining the growth conditions of the animal cells therefrom and thus controlling the cultivation conditions. When the ratio L/G, which is preferably from greater than 0 to 0.6, is outside the desired range, the dissolved oxygen concentration and/or the glucose concentration in the culture medium may be controlled by increasing the dissolved oxygen concentration in the culture medium and/or decreasing the glucose concentration therein.

5. 发明专利

DE3871573D1 未知
公开(公告)号：DE3871573D1
公开(公告)日：1992-07-09
申请号：DE3871573
申请日：1988-02-19
申请人： HITACHI LTD
发明人： SHIMIZU NORIO , FUKUZONO SHINICHI , FUJIMORI KIYOSHI , NISHIMURA NOBUKO , ODAWARA YOJI
IPC分类号： C12M1/36 , C12N1/00 , C12N1/20 , C12P1/00 , C12P21/02
摘要： In a method for cultivation of microorganisms or animal cell or plant cells to produce metabolites, high density cultivation, high cell yield and high production of desired products can be achieved by performing cultivation through monitoring acetate concentration in culture broth and regulating assimilation of acetate in the culture broth by the microorganisms or animal cell or plant cells to control the acetate concentration to a set value or less, and as an apparatus for such cultivation, preferred is an apparatus comprising a culture tank for performing cultivation, an acetate concentration analyzer in culture broth, a substrate tank for storing substrate, a substrate feeding device of variable flow type for feeding substrate and a control device for outputting a signal for controlling a substrate flow from the substrate feeding device based on a signal from the analyzer.

6. 发明专利

DE2938291A1 未知
公开(公告)号：DE2938291A1
公开(公告)日：1980-04-03
申请号：DE2938291
申请日：1979-09-21
申请人： HITACHI LTD
发明人： SHIMIZU NORIO , ODAWARA YOZI , HITACHI IBARAKI , MAZAKI YASUNORI
IPC分类号： C02F3/12 , C02F3/34 , C12K3/00 , C02C1/02 , C02C5/10
摘要： The invention relates to an improvement of the floc-formation property of activated sludge contained in waste water. A waste water treatment process comprises steps culturing a novel strain-Alcaligenes faecalis HRL-1 - and adding the cultured cells to to-be-treated waste water.

8. 发明专利

DE69628389D1 未知
公开(公告)号：DE69628389D1
公开(公告)日：2003-07-03
申请号：DE69628389
申请日：1996-11-08
申请人： HITACHI LTD
发明人： YASUDA KENJI , UMEMURA SHIN-ICHIRO , TAKEDA KAZUO , TAMURA MITSURU , SHIMIZU NORIO
IPC分类号： G01N1/36 , B01D21/00 , B01D43/00 , B01J19/10 , B01J8/16
摘要： An apparatus for exerting an ultrasound beam on a sample solution containing particles to be concentrated, separated or arranged permits arbitrarily controlling the spatial distribution of the potential energy created by the ultrasound beam and concentrating, separating or periodically arranging the particles. Irradiation ultrasound sources (631, 632) for generating ultrasound beams are provided on a chamber holding said solution to create an ultrasonic intensity distribution for producing a position potential energy distribution used to exert on each particle a force forwarded in a predetermined direction or a force staying at a predetermined region. Thus, a specific spatial distribution of the potential energy can be realised by ultrasound beams each having a specific intensity, a specific frequency and a specific phase or by an ultrasound beam formed by the mutual superposition of such beams. Further, at least one suction hole (671) for recovering separated solvents or particles is defined in a wall surface of the chamber, which is orthogonal to the flow of the sample solution.

9. 发明专利

DE69122545D1 未知
公开(公告)号：DE69122545D1
公开(公告)日：1996-11-14
申请号：DE69122545
申请日：1991-02-21
申请人： HITACHI LTD
发明人： SHIMIZU NORIO , FUJIMORI KIYOSHI , FUKUZONO SHINICHI , KOTOMURA NAOE
IPC分类号： C12N1/21 , C07K14/48 , C12N1/11 , C12N15/12 , C12P21/02 , C12R1/19 , C12N15/71

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