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1. 发明申请

WO2013158114A1 INTEGRATED SENSORS 审中-公开
标题翻译：集成传感器
公开(公告)号：WO2013158114A1
公开(公告)日：2013-10-24
申请号：PCT/US2012/034448
申请日：2012-04-20
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , BRATKOVSKI, Alexandre M. , LI, Zhiyong , WU, Wei , HU, Min , WILLIAMS, R. Stanley , KIM, Ansoon
发明人： BRATKOVSKI, Alexandre M. , LI, Zhiyong , WU, Wei , HU, Min , WILLIAMS, R. Stanley , KIM, Ansoon
IPC分类号： G01N35/00 , G01N21/00
CPC分类号： G01N21/658 , B01L3/5088 , B01L2300/0627 , B01L2300/0819 , B01L2300/161 , G01N21/648 , G01N35/00009 , G01N2035/00019
摘要： Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.
摘要翻译：本文公开了集成传感器的示例。集成传感器的示例包括形成在基板的表面上的基板和感测构件。感测构件包括可折叠信号放大结构和围绕可折叠信号放大结构的区域，其使得能够将暴露于其的液滴自动定位到可折叠信号放大结构。

2. 发明申请

WO2011133144A1 A SELF-ARRANGING, LUMINESCENCE-ENHANCEMENT DEVICE FOR SURFACE-ENHANCED LUMINESCENCE 审中-公开
标题翻译：表面增强发光的自亮装置，增亮装置
公开(公告)号：WO2011133144A1
公开(公告)日：2011-10-27
申请号：PCT/US2010/031809
申请日：2010-04-20
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , LI, Zhiyong , HU, Min , OU, Fung Suong , WU, Wei
发明人： LI, Zhiyong , HU, Min , OU, Fung Suong , WU, Wei
IPC分类号： G01J3/44 , G01N21/65
CPC分类号： G01N21/658 , G01N21/648
摘要： A self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence. The self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence includes a substrate 110, and a plurality 120 of flexible columnar structures. A flexible columnar structure 120-1 of the plurality 120 includes a flexible column 120-1A, and a metallic cap 120-1B coupled to the apex 120-1C of the flexible column 120-1A. At least the flexible columnar structure 120-1 and a second flexible columnar structure 120-2 are configured to self-arrange into a close-packed configuration with at least one molecule 220-1 disposed between at least the metallic cap 120-1B and a second metallic cap 120-2B of respective flexible columnar structure 120-1 and second flexible columnar structure 120-2.
摘要翻译：用于表面增强发光的自配置发光增强装置101。用于表面增强发光的自配置发光增强装置101包括基板110和多个120个柔性柱状结构。多个120的柔性柱状结构120-1包括柔性柱120-1A以及耦合到柔性柱120-1A的顶点120-1C的金属盖120-1B。至少柔性柱状结构120-1和第二柔性柱状结构120-2构造成自配置成紧密堆积构造，其中至少一个分子220-1设置在至少金属盖120-1B和各个柔性柱状结构120-1的第二金属盖120-2B和第二柔性柱状结构120-2。

3. 发明申请

WO2012015443A1 OPTICAL FIBER SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) PROBE 审中-公开
标题翻译：光纤表面增强拉曼光谱（SERS）探头
公开(公告)号：WO2012015443A1
公开(公告)日：2012-02-02
申请号：PCT/US2010/044039
申请日：2010-07-30
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , LI, Zhiyong , HU, Min , WU, Wei
发明人： LI, Zhiyong , HU, Min , WU, Wei
IPC分类号： G01J3/44 , G01N21/65
CPC分类号： G01N21/658
摘要： A surface enhanced Raman spectroscopy (SERS) probe apparatus (100) and a method (300) of SERS probing employ Raman-active surfaces of a plurality of nanoscale field concentrator (NFC) structures (130) at a terminal end (114) of an optical fiber (110). The SERS probe apparatus (100) includes an optical fiber (110) having an optical path (112) and a terminal end (114) that terminates the optical path (112). The SERS probe apparatus (100) further includes a plurality of NFC structures (130) and nanoparticles (140) on surfaces (120) of the plurality of NFC structures (130). First ends of the NFC structures (130) are adjacent to the terminal end (114) of optical fiber (110). The nanoparticles (140) are Raman active to an analyte (102).
摘要翻译：在SERS探测的表面增强拉曼光谱（SERS）探针装置（100）和方法（300）中，在多个纳米尺度场集中器（NFC）结构（130）的末端（114）处使用拉曼活性表面光纤（110）。 SERS探针装置（100）包括具有光路（112）的光纤（110）和终止光路（112）的终端（114）。 SERS探针装置（100）还包括在多个NFC结构（130）的表面（120）上的多个NFC结构（130）和纳米颗粒（140）。 NFC结构（130）的第一端与光纤（110）的终端（114）相邻。纳米颗粒（140）是对分析物（102）有活性的拉曼。

4. 发明申请

WO2011133143A1 MULTI-PILLAR STRUCTURE FOR MOLECULAR ANALYSIS 审中-公开
标题翻译：用于分子分析的多支架结构
公开(公告)号：WO2011133143A1
公开(公告)日：2011-10-27
申请号：PCT/US2010/031790
申请日：2010-04-20
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , LI, Zhiyong , HU, Min , OU, Fung Suong , WU, Wei , WILLIAMS, R. Stanley
发明人： LI, Zhiyong , HU, Min , OU, Fung Suong , WU, Wei , WILLIAMS, R. Stanley
IPC分类号： G01N21/65 , G01N33/483 , B82B1/00 , G01J3/44
CPC分类号： G01N21/658
摘要： A multi-pillar structure for molecular analysis is provided. The structure comprises at least two nanopoles, each nanopole attached at one end to a substrate and freely movable along its length. The opposite ends of the at least two nanopoles are each capable of movement toward each other to trap at least one analyte molecule at their opposite ends. Each nanopole is coated with a metal coating. An array of such multi-pillar structures is also provided. A method for preparing the multi-pillar structure is further provided.
摘要翻译：提供了一种用于分子分析的多支柱结构。该结构包括至少两个纳米微粒，每个纳米孔一端连接到基底上，并可沿其长度自由移动。至少两个纳米球的相对端各自能够相互移动以在其相对端捕获至少一种分析物分子。每个纳米孔涂有金属涂层。还提供了这种多支柱结构的阵列。还提供了一种制备多支柱结构的方法。

5. 发明申请

WO2013062554A1 APPARATUS FOR FILTERING SPECIES 审中-公开
标题翻译：过滤器物种
公开(公告)号：WO2013062554A1
公开(公告)日：2013-05-02
申请号：PCT/US2011/058130
申请日：2011-10-27
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , KIM, Ansoon , LI, Zhiyong , WU, Wei
发明人： KIM, Ansoon , LI, Zhiyong , WU, Wei
IPC分类号： G01N21/65 , G01N1/28
CPC分类号： G01N21/05 , B82Y20/00 , G01N21/554 , G01N21/658 , G01N33/491 , G01N2001/4088 , G01N2021/651
摘要： An apparatus for filtering species in a fluid includes a body having a first side and a second side, a first set of nano-fingers positioned on the body near the first side, a second set of nano-fingers positioned on the body closer to the second side than the first set of nano-fingers, wherein the nano-fingers in the second set of nano-fingers are arranged on the body at a relatively more densely than the nano-fingers in the first set of nano-fingers, and a cover positioned over the first set of nano-fingers and the second set of nano-fingers to form a channel with the body within which the first and second sets of nano- fingers are positioned.
摘要翻译：用于过滤流体中的物质的装置包括具有第一侧和第二侧的主体，位于第一侧附近的本体上的第一组纳米手指，位于身体上的第二组纳米手指，第二组纳米手指的第二组，其中第二组纳米手指中的纳米手指以比第一组纳米手指中的纳米手指相对更密集地布置在身体上，并且覆盖物定位在第一组纳米指状物和第二组纳米手指之上，以与第一和第二组纳米手指定位的主体形成通道。

6. 发明申请

WO2011049582A1 RAMAN SPECTROSCOPY LIGHT AMPLIFYING STRUCTURE 审中-公开
标题翻译：拉曼光谱放大结构
公开(公告)号：WO2011049582A1
公开(公告)日：2011-04-28
申请号：PCT/US2009/061904
申请日：2009-10-23
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , WU, Wei , LI, Jingjing , LI, Zhiyong , WANG, Shih-Yuan , BRATKOVSKI, Alexandre
发明人： WU, Wei , LI, Jingjing , LI, Zhiyong , WANG, Shih-Yuan , BRATKOVSKI, Alexandre
IPC分类号： G01J3/44 , G01N21/65
CPC分类号： G01N21/658
摘要： A light amplifying structure (100) for Raman spectroscopy includes a resonant cavity (108). A distance between a first portion (102B) and a second portion (102A) of the structure (100) forming the resonant (cavity (108) is used to amplify excitation light emitted from a light source (420) into the resonant cavity (108) at a first resonant frequency of the resonant cavity (108). Also, the resonant cavity (108) amplifies radiated light radiated from a predetermined molecule excited by the excitation light in the resonant cavity at a second resonant frequency of the resonant cavity (108).
摘要翻译：用于拉曼光谱的光放大结构（100）包括谐振腔（108）。形成谐振腔（108）的结构（100）的第一部分（102B）和第二部分（102A）之间的距离用于将从光源（420）发射的激发光放大到谐振腔（108）谐振腔（108）在谐振腔（108）的第二谐振频率处放大从由谐振腔中的激发光激发的预定分子辐射的辐射光）。

7. 发明申请

WO2006081565A1 MONOLITHIC SYSTEM AND METHOD FOR ENHANCED RAMAN SPECTROSCOPY 审中-公开
标题翻译：用于增强拉曼光谱的单体系统和方法
公开(公告)号：WO2006081565A1
公开(公告)日：2006-08-03
申请号：PCT/US2006/003264
申请日：2006-01-26
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , ISLAM, M., Saiful , WANG, Shih-Yuan , WU, Wei , LI, Zhiyong , WILLIAMS, R., Stanley
发明人： ISLAM, M., Saiful , WANG, Shih-Yuan , WU, Wei , LI, Zhiyong , WILLIAMS, R., Stanley
IPC分类号： G01N21/65 , G01J3/44
CPC分类号： G01N21/658 , G01N2201/0873
摘要： Devices, systems, and methods for enhancing Raman spectroscopy and hyper-Raman are disclosed. A molecular analysis device (100', 100") for performing Raman spectroscopy comprises a substrate (110) and a laser source (120) disposed on the substrate (110). The laser source (120) may be configured for generating a laser radiation (125), which may irradiate an analyte (31 ) disposed on a Raman enhancement structure (300). The Raman enhancement structure (300) may be disposed in a waveguide (130). The molecular analysis device (100', 100") also includes a wavelength demultiplexer (240) and radiation sensors (290) disposed on the substrate (110) and configured for receiving a Raman scattered radiation (160), which may be generated by the irradiation of the analyte (310) and Raman enhancement structure (300).
摘要翻译：公开了用于增强拉曼光谱和超拉曼的装置，系统和方法。用于进行拉曼光谱分析的分子分析装置（100'，100“）包括基板（110）和设置在基板（110）上的激光源（120），激光源（120）可以被配置为产生激光辐射（125），其可以照射设置在拉曼增强结构（300）上的分析物（31），拉曼增强结构（300）可以设置在波导管（130）中，分子分析装置（100'，100“）还包括布置在衬底（110）上并被配置用于接收拉曼散射辐射（160）的波长解复用器（240）和辐射传感器（290），其可以通过分析物（310）的照射和拉曼增强结构（300）。

8. 发明申请

WO2013048446A1 DEVICES TO DETECT A SUBSTANCE AND METHODS OF PRODUCING SUCH A DEVICE 审中-公开
标题翻译：检测物质的装置和生产这种装置的方法
公开(公告)号：WO2013048446A1
公开(公告)日：2013-04-04
申请号：PCT/US2011/054283
申请日：2011-09-30
申请人： HEWLET-PACKARD DEVELOPMENT COMPANY, L.P. , WU, Wei , LI, Zhiyong , KIM, Ansoon , HU, Min , STUKE, Michael Josef
发明人： WU, Wei , LI, Zhiyong , KIM, Ansoon , HU, Min , STUKE, Michael Josef
IPC分类号： G01N1/36 , G01N21/64 , G01N21/65 , G01N33/00
CPC分类号： G01N31/22 , B01L3/5085 , B01L3/50853 , B01L2200/141 , B01L2300/0636 , B01L2300/069 , B01L2300/0819 , B82Y15/00 , G01N21/648 , G01N21/658 , G01N2201/0227 , G01N2201/023 , Y10T436/25
摘要： Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.
摘要翻译：公开了检测物质的装置和制造这种装置的方法。用于检测物质的示例性装置包括限定外部可触及室的壳体和用于封闭室的至少一部分的密封件。该示例性装置还包括基底，其包括位于腔室内的纳米颗粒。纳米颗粒暴露于物质时与物质反应。该示例性装置还包括室内的非分析溶液以保护纳米颗粒免于过早暴露。

9. 发明申请

WO2011040923A1 WAVEGUIDES CONFIGURED WITH ARRAYS OF FEATURES FOR PERFORMING RAMAN SPECTROSCOPY 审中-公开
标题翻译：配置有执行拉曼光谱特征的阵列的波形
公开(公告)号：WO2011040923A1
公开(公告)日：2011-04-07
申请号：PCT/US2009/059219
申请日：2009-10-01
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , TANG, Jing , WU, Wei , XIA, Qiangfei
发明人： TANG, Jing , WU, Wei , XIA, Qiangfei
IPC分类号： G01J3/44 , G01N21/65 , G01N33/483
CPC分类号： G01N21/658 , G01N21/7743
摘要： Embodiments of the present invention are directed to systems for performing surface-enhanced Raman spectroscopy. In one embodiment, a system for performing Raman spectroscopy includes a waveguide layer (102,402,702,902) configured with at least one array of features, and a material (110,410,710,910) disposed on at least a portion of the features. Each array of features and the waveguide layer are configured to provide guided-mode resonance for at least one wavelength of electromagnetic radiation. The electromagnetic radiation produces enhanced Raman scattered light from analyte molecules located on or in proximity to the material.
摘要翻译：本发明的实施例涉及用于进行表面增强拉曼光谱的系统。在一个实施例中，用于执行拉曼光谱的系统包括配置有至少一个特征阵列的波导层（102,402,702,902）和布置在特征的至少一部分上的材料（110,410,710,910）。每个特征阵列和波导层被配置为为至少一个波长的电磁辐射提供导模谐振。电磁辐射产生来自位于材料上或附近的分析物分子的增强的拉曼散射光。

10. 发明申请

WO2009075684A1 CONTROLLABLE OPTICAL RING RESONATOR HAVING PERIODICALLY SPACED CONTROL ELECTRODES 审中-公开
标题翻译：具有周期性空间控制电极的可控光环谐振器
公开(公告)号：WO2009075684A1
公开(公告)日：2009-06-18
申请号：PCT/US2007/087307
申请日：2007-12-12
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , MORRIS, Terrel L. , TAN, Michael R. , WU, Wei , WANG, Shih-Yuan
发明人： MORRIS, Terrel L. , TAN, Michael R. , WU, Wei , WANG, Shih-Yuan
IPC分类号： G02B6/12 , G01C19/72
CPC分类号： G01C19/721 , G02F1/3132 , G02F2203/15
摘要： A controllable optical ring resonator, a photonic system and a method of controlling an optical ring resonator employ control electrodes periodically spaced apart along a closed loop optical path of an optical waveguide. The controllable optical ring resonator includes the optical waveguide and a plurality of the periodically spaced control electrodes. The photonic system includes an input optical waveguide segment and the controllable optical ring resonator adjacent and optically coupled to the segment. The method includes providing the plurality of periodically spaced control electrodes, providing an optical signal within the optical path, and addressing one or more of the control electrodes to interact with the optical signal within the optical path.
摘要翻译：可控光环谐振器，光子系统和控制光环谐振器的方法采用沿着光波导的闭环光路周期性间隔开的控制电极。可控光环谐振器包括光波导和多个周期性间隔的控制电极。光子系统包括输入光波导段和可控光环谐振器，其邻近并光耦合到段。该方法包括提供多个周期性间隔的控制电极，在光路内提供光信号，以及寻址一个或多个控制电极以与光路内的光信号相互作用。

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