专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08399511B2 Two types of crystalline of pinocembrin, their preparation and their use for manufacture of pharmaceutical compositions 有权
标题翻译：两种类型的尖晶石结晶，其制备及其用于制备药物组合物的用途
公开(公告)号：US08399511B2
公开(公告)日：2013-03-19
申请号：US13128896
申请日：2008-11-13
申请人： Guanhua Du , Yang Lv , Song Wu , Ke Wang , Ying Chang , Zhihong Yang , Yuanfeng Tong , Mei Gao
发明人： Guanhua Du , Yang Lv , Song Wu , Ke Wang , Ying Chang , Zhihong Yang , Yuanfeng Tong , Mei Gao
IPC分类号： A61K31/353 , C07D311/32
CPC分类号： C07D311/22 , A61K31/353 , C07D403/04 , C07D403/08
摘要： Two crystalline forms of pinocembrin of formula (I): α and β, their preparation and their use for manufacture of pharmaceutical compositions. There exists difference between them in bioavailability. They are used for treating and preventing cerebral ischemic diseases by protective action of neurovascular unit, and enhancing blood drug level in vivo.
摘要翻译：式（I）的噻吗啉的两种结晶形式：α和＆bgr;它们的制备及其在制备药物组合物中的用途。它们之间在生物利用度上存在差异。它们用于通过神经血管单位的保护作用治疗和预防脑缺血疾病，并增加体内血药浓度。

2. 发明申请

US20110213024A1 TWO TYPES OF CRYSTALLINE OF PINOCEMBRIN, THEIR PREPARATION AND THEIR USE FOR MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS 有权
标题翻译：胶囊蛋白的两种类型，其制备方法及其制备药物组合物的用途
公开(公告)号：US20110213024A1
公开(公告)日：2011-09-01
申请号：US13128896
申请日：2008-11-13
申请人： Guanhua Du , Yang Lv , Song Wu , Ke Wang , Ying Chang , Zhihong Yang , Yuanfeng Tong , Mei Gao
发明人： Guanhua Du , Yang Lv , Song Wu , Ke Wang , Ying Chang , Zhihong Yang , Yuanfeng Tong , Mei Gao
IPC分类号： A61K31/352 , C07D311/32 , A61P9/10
CPC分类号： C07D311/22 , A61K31/353 , C07D403/04 , C07D403/08
摘要： Two crystalline forms of pinocembrin of formula (I): α and β, their preparation and their use for manufacture of pharmaceutical compositions. There exists difference between them in bioavailability. They are used for treating and preventing cerebral ischemic diseases by protective action of neurovascular unit, and enhancing blood drug level in vivo.
摘要翻译：式（I）的噻吗啉的两种结晶形式：α和＆bgr;它们的制备及其在制备药物组合物中的用途。它们之间在生物利用度上存在差异。它们用于通过神经血管单位的保护作用治疗和预防脑缺血疾病，并增加体内血药浓度。

3. 发明申请

US20110319401A1 FIVE CRYSTAL FORMS, METHODS OF PREPARATION, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS OF XLF-III-43 有权
标题翻译：五水晶形态，制备方法，药物组合物和XLF-III-43的应用
公开(公告)号：US20110319401A1
公开(公告)日：2011-12-29
申请号：US13131492
申请日：2009-11-28
申请人： Yang Lv , Xiaoguang Chen , Ping Xie , Li Zhang , Cheng Wang
发明人： Yang Lv , Xiaoguang Chen , Ping Xie , Li Zhang , Cheng Wang
IPC分类号： A61K31/539 , A61P13/12 , A61P35/00 , A61P9/12 , A61P3/10 , C07D498/14 , A61P9/00
CPC分类号： C07D311/16 , A61K31/37
摘要： This invention discloses that the five crystal forms of XLF-III-43 can be used as crude drugs. The invention also relates to the preparation methods of the five crystal forms of XLF-III-43 as crude drugs, to the applications of the sterling of the five crystal forms of XLF-III-43 and mixed crystals in different proportions as medicinally active components to develop various kinds of medicines and compound medicines. In addition, this invention also relates to applying the crystal samples of XLF-III-43 as crude drugs to treat kidney dysfunction, cardiocerebral vessel diseases, hypertension, type II diabetic mellitus, complications of hypertension and diabetic mellitus, tumor, precancerosis, edema, and achieves therapeutic effects by enhancing blood drug levels resulted from effects of crystal forms in the processes of treating all kinds of diseases.
摘要翻译：本发明公开了XLF-III-43的五种晶体形式可用作生药。本发明还涉及作为生药的XLF-III-43的五种结晶形式的制备方法，将XLF-III-43的五种晶型和不同比例的混晶的英制应用作为药物活性成分开发各种药品和复合药物。此外，本发明还涉及将XLF-III-43的晶体样品作为生药用于治疗肾功能障碍，心脑血管疾病，高血压，II型糖尿病，高血压和糖尿病并发症，肿瘤，癌前病变，水肿，并且通过在治疗各种疾病的过程中增强由结晶形式的作用引起的血药浓度来达到治疗效果。

4. 发明授权

US08729280B2 Five crystal forms, methods of preparation, pharmaceutical compositions and applications of XLF-III-43 有权
标题翻译：五种晶体形式，制备方法，药物组合物和XLF-III-43的应用
公开(公告)号：US08729280B2
公开(公告)日：2014-05-20
申请号：US13131492
申请日：2009-11-28
申请人： Yang Lv , Xiaoguang Chen , Ping Xie , Li Zhang , Cheng Wang
发明人： Yang Lv , Xiaoguang Chen , Ping Xie , Li Zhang , Cheng Wang
IPC分类号： C07D311/00
CPC分类号： C07D311/16 , A61K31/37
摘要： This invention discloses that the five crystal forms of XLF-III-43 can be used as crude drugs. The invention also relates to the preparation methods of the five crystal forms of XLF-III-43 as crude drugs, to the applications of the sterling of the five crystal forms of XLF-III-43 and mixed crystals in different proportions as medicinally active components to develop various kinds of medicines and compound medicines. In addition, this invention also relates to applying the crystal samples of XLF-III-43 as crude drugs to treat kidney dysfunction, cardiocerebral vessel diseases, hypertension, type II diabetic mellitus, complications of hypertension and diabetic mellitus, tumor, precancerosis, edema, and achieves therapeutic effects by enhancing blood drug levels resulted from effects of crystal forms in the processes of treating all kinds of diseases.
摘要翻译：本发明公开了XLF-III-43的五种晶体形式可用作生药。本发明还涉及作为生药的XLF-III-43的五种结晶形式的制备方法，将XLF-III-43的五种晶型和不同比例的混晶的英制应用作为药物活性成分开发各种药品和复合药物。此外，本发明还涉及将XLF-III-43的晶体样品作为生药用于治疗肾功能障碍，心脑血管疾病，高血压，II型糖尿病，高血压和糖尿病并发症，肿瘤，癌前病变，水肿，并且通过在治疗各种疾病的过程中增强由结晶形式的作用引起的血药浓度来达到治疗效果。

5. 发明申请

US20120322886A1 USE OF A SATURATED AMINES COMPOUND IN MANUFACTURE OF MEDICAMENTS FOR MOBILIZING PERIPHERAL BLOOD HEMATOPOIETIC STEM CELL 审中-公开
标题翻译：饱和氨基化合物在制造外周血中HEMATOPOIETIC STEM细胞的药物制备中的应用
公开(公告)号：US20120322886A1
公开(公告)日：2012-12-20
申请号：US13514873
申请日：2010-12-08
申请人： Xuetao Pei , Wei Shi , Yanhua Li , Xiangliang Ren , Yang Lv , Shuangshuang Shi , Lin Chen , Xue Nan , Wen Yue
发明人： Xuetao Pei , Wei Shi , Yanhua Li , Xiangliang Ren , Yang Lv , Shuangshuang Shi , Lin Chen , Xue Nan , Wen Yue
IPC分类号： A61K31/132 , A61P7/00
CPC分类号： A61K31/132
摘要： The invention provides a new use of a saturated amine compound, i.e., in manufacture of peripheral blood hematopoietic stem cell mobilizing agents. Experiments show that this compound (Code No. TA01) can efficiently mobilize hematopoietic stem cells into peripheral blood, and is a new type of hematopoietic stem cell mobilizing agents. The invention can play an important role in research and development of mobilizing agents for mobilizing hematopoietic stem cells into peripheral blood and has a promising application perspective.
摘要翻译：本发明提供饱和胺化合物的新用途，即制造外周血造血干细胞移动剂。实验表明，该化合物（代号TA01）可以有效地将造血干细胞移植到外周血中，是一种新型的造血干细胞移动剂。本发明可以在将造血干细胞动员到外周血中的动员剂的研究和开发中发挥重要作用，具有广阔的应用前景。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式